NSTL国家科技图书文献中心

1. TMCO1 promotes ferroptosis and ECM deposition in glaucomatous trabecular meshwork via ERK1/2 signaling NSTL国家科技图书文献中心

Zhang, Yang | Han, Ruiqi ... - 《Biochimica et biophysica acta.Molecular basis of disease》 - 2025,1871(1) - 167530～167530 - 共15页

摘要： ferroptosis in human trabecular* meshwork cells (HTMCs* | extracellular matrix (ECM) deposition in the trabecular | meshwork (TM). Transmembrane and coiled-coil domain | Glaucoma, a leading cause of global blindness | , is marked by irreversible retinal ganglion cells

关键词： glaucoam | trabecular meshwork | ferroptosis | ECM deposition | ERK/MAPK

2. Autophagy activation ameliorates the fibrosis of trabecular meshwork cells induced by TGFβ2 through the promotion of fibrotic proteins degradation NSTL国家科技图书文献中心

Gang,Wang | Rumeng,Zhao ... - 《Human cell》 - 2025,38(1) - Article 4～Article 4 - 共12页

摘要： partial glaucoma patients, and induced trabecular | meshwork (TM) fibrosis, which could cause TM cells | Abstract The level of transforming growth | factor-beta2 (TGFβ2) is elevated in aqueous humor of | dysfunction and lead to intraocular pressure (IOP) elevation

关键词： Autophagy | Trabecular meshwork cells | Fibrosis | TGFβ2 | Smad3 | Rapamycin

3. Silencing miR-126-5p protects trabecular meshwork cells against chronic oxidative injury by upregulating HSPB8 to activate PI3K/AKT pathway NSTL国家科技图书文献中心

Jia, Tianqi | Guo, Yujia ... - 《Journal of molecular histology》 - 2025,56(1) - Article: 58～Article: 58 - 共11页

摘要： the pathophysiology of the trabecular* meshwork (TM* | investigated the function of miR-126-5p in human trabecular | meshwork cells (TMCs) under chronic oxidative stress (COS | Chronic oxidative stress (COS) is related to | ) in glaucoma. MicroRNAs (miRNAs) have a key role in

关键词： Glaucoma | miR-126-5p | PI3K/AKT pathway | HSPB8

4. Identification of a chromatin regulator signature and potential candidate drugs for primary open-angle glaucoma NSTL国家科技图书文献中心

Zhang, Xinyue | Xiao, Lulu ... - 《Epigenomics》 - 2025,17(5/6) - 377～387 - 共11页

摘要： expression profile of CRs in trabecular* meshwork (TM* | human trabecular* meshwork cell (HTMC) oxidative stress* | AimsThis research aims to establish a | chromatin regulator (CR) signature to provide new | epigenetic insights into the pathogenesis of primary open

关键词： Glaucoma | POAG | chromatin regulators | trabecular meshwork | oxidative stress

5. Preliminary antifibrotic and vasoconstrictor effects of adrenaline in Schlemm's canal and suprachoroidal minimally invasive glaucoma surgery in primary open-angle glaucoma NSTL国家科技图书文献中心

Luo, Jinyuan | Fajardo-Sanchez, Jul...... - 《Graefe's archive for clinical and experimental ophthalmology》 - 2025,263(2) - 489～500 - 共12页

摘要：). Methods Human trabecular* meshwork (TM) cells were* | risk of bleeding from the trabecular* meshwork and* | Purpose To investigate the antifibrotic and | vasoconstrictor effects of adrenaline in Schlemm's canal and | suprachoroidal minimally invasive glaucoma surgery (MIGS

关键词： Glaucoma | Adrenaline | Fibrosis | MIGS

6. Glaucoma Surgery SOS: Emergency Department Utilization Greater among Younger and First-Time Surgical Patients with Glaucoma NSTL国家科技图书文献中心

Gross, Andrew W. | Aggarwal, Sahil ... - 《Ophthalmology..Glaucoma.》 - 2025,8(1) - 37～45 - 共9页

摘要： trabecular meshwork bypass stent to present to the ED with | glaucoma surgery. Trabecular* meshwork bypass stent, but* | not trabecular* meshwork excision and/or Schlemm* | Purpose: To describe the frequency, findings | , and interventions of patients' emergency department

关键词： Emergency department | Glaucoma surgery | Postoperative

7. Manufacturing and characterisation of 3D-printed sustained-release Timolol implants for glaucoma treatment NSTL国家科技图书文献中心

Paleel, Fathima | Qin, Mengqi ... - 《Drug delivery and translational research》 - 2025,15(1) - 242～252 - 共11页

摘要： implants on cell viability in human trabecular meshwork | trabecular cells. This study shows proof of concept that | Timolol maleate (TML) is a beta-blocker drug | that is commonly used to lower the intraocular | pressure in glaucoma. This study focused on using a 3D

关键词： Glaucoma | Timolol | 3D printing | Drug-eluting implants | Sustained-release

8. Investigational drugs for glaucoma: novel mechanistic approaches of preclinical agents NSTL国家科技图书文献中心

Irkec, Murat | Konstas, Anastasios ...... - 《Expert opinion on investigational drugs.》 - 2025,34(3) - 231～243 - 共13页

摘要： targeting trabecular* meshwork function, neuroprotection* | IntroductionGlaucoma is a neurodegenerative | disease that causes irreversible blindness worldwide. It | results from retinal ganglion cell (RGC) loss and | progressive optic nerve damage, mainly associated with

关键词： Adenosine | brimonidine | glaucoma | nanoformulation | neuroprotection | nutrients

9. Physiological activation of liver X receptor provides protection against ocular inflammation in uveitic glaucoma NSTL国家科技图书文献中心

Ju, Hyun Hee | Lee, Jiyoung ... - 《Biochimica et biophysica acta.Molecular basis of disease》 - 2025,1871(1) - 167573～167573 - 共13页

摘要： human trabecular* meshwork cells in response to CMV* | Virus-induced trabeculitis is considered a | significant cause of uveitic glaucoma, being marked by a | sudden increase in intraocular pressure and relatively | mild inflammation in the anterior chamber of the eye

关键词： Liver X receptor | Cytomegalovirus | Uveitic glaucoma

10. 3D Finite Element Modeling of Femtosecond Laser Trabeculotomy NSTL国家科技图书文献中心

Djotyan, Gagik P. | Mikula, Eric R.... - 《Lasers in surgery and medicine.》 - 2025,57(2) - 219～228 - 共10页

摘要： trabecular meshwork (TM) to decrease intraocular pressure | ObjectivesFemtosecond laser image guided high | precision trabeculotomy (FLigHT) is a novel open-angle | glaucoma treatment. The procedure non-invasively creates | aqueous humor (AH) drainage channel from the anterior

摘要： ferroptosis in human trabecular* meshwork cells (HTMCs* | extracellular matrix (ECM) deposition in the trabecular | meshwork (TM). Transmembrane and coiled-coil domain | Glaucoma, a leading cause of global blindness | , is marked by irreversible retinal ganglion cells

关键词： glaucoam | trabecular meshwork | ferroptosis | ECM deposition | ERK/MAPK

摘要： partial glaucoma patients, and induced trabecular | meshwork (TM) fibrosis, which could cause TM cells | Abstract The level of transforming growth | factor-beta2 (TGFβ2) is elevated in aqueous humor of | dysfunction and lead to intraocular pressure (IOP) elevation

关键词： Autophagy | Trabecular meshwork cells | Fibrosis | TGFβ2 | Smad3 | Rapamycin

摘要： the pathophysiology of the trabecular* meshwork (TM* | investigated the function of miR-126-5p in human trabecular | meshwork cells (TMCs) under chronic oxidative stress (COS | Chronic oxidative stress (COS) is related to | ) in glaucoma. MicroRNAs (miRNAs) have a key role in

关键词： Glaucoma | miR-126-5p | PI3K/AKT pathway | HSPB8

摘要： expression profile of CRs in trabecular* meshwork (TM* | human trabecular* meshwork cell (HTMC) oxidative stress* | AimsThis research aims to establish a | chromatin regulator (CR) signature to provide new | epigenetic insights into the pathogenesis of primary open

关键词： Glaucoma | POAG | chromatin regulators | trabecular meshwork | oxidative stress

摘要：). Methods Human trabecular* meshwork (TM) cells were* | risk of bleeding from the trabecular* meshwork and* | Purpose To investigate the antifibrotic and | vasoconstrictor effects of adrenaline in Schlemm's canal and | suprachoroidal minimally invasive glaucoma surgery (MIGS

关键词： Glaucoma | Adrenaline | Fibrosis | MIGS

摘要： trabecular meshwork bypass stent to present to the ED with | glaucoma surgery. Trabecular* meshwork bypass stent, but* | not trabecular* meshwork excision and/or Schlemm* | Purpose: To describe the frequency, findings | , and interventions of patients' emergency department

关键词： Emergency department | Glaucoma surgery | Postoperative

摘要： implants on cell viability in human trabecular meshwork | trabecular cells. This study shows proof of concept that | Timolol maleate (TML) is a beta-blocker drug | that is commonly used to lower the intraocular | pressure in glaucoma. This study focused on using a 3D

关键词： Glaucoma | Timolol | 3D printing | Drug-eluting implants | Sustained-release

摘要： targeting trabecular* meshwork function, neuroprotection* | IntroductionGlaucoma is a neurodegenerative | disease that causes irreversible blindness worldwide. It | results from retinal ganglion cell (RGC) loss and | progressive optic nerve damage, mainly associated with

关键词： Adenosine | brimonidine | glaucoma | nanoformulation | neuroprotection | nutrients

摘要： human trabecular* meshwork cells in response to CMV* | Virus-induced trabeculitis is considered a | significant cause of uveitic glaucoma, being marked by a | sudden increase in intraocular pressure and relatively | mild inflammation in the anterior chamber of the eye

关键词： Liver X receptor | Cytomegalovirus | Uveitic glaucoma

摘要： trabecular meshwork (TM) to decrease intraocular pressure | ObjectivesFemtosecond laser image guided high | precision trabeculotomy (FLigHT) is a novel open-angle | glaucoma treatment. The procedure non-invasively creates | aqueous humor (AH) drainage channel from the anterior

关键词： aqueous humor | femtosecond laser trabeculotomy | finite element modeling | intraocular pressure | open-angle glaucoma

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： ferroptosis in human trabecular meshwork cells (HTMCs | extracellular matrix (ECM) deposition in the trabecular | meshwork (TM). Transmembrane and coiled-coil domain | Glaucoma, a leading cause of global blindness | , is marked by irreversible retinal ganglion cells

关键词： glaucoam | trabecular meshwork | ferroptosis | ECM deposition | ERK/MAPK

摘要： partial glaucoma patients, and induced trabecular | meshwork (TM) fibrosis, which could cause TM cells | Abstract The level of transforming growth | factor-beta2 (TGFβ2) is elevated in aqueous humor of | dysfunction and lead to intraocular pressure (IOP) elevation

关键词： Autophagy | Trabecular meshwork cells | Fibrosis | TGFβ2 | Smad3 | Rapamycin

摘要： the pathophysiology of the trabecular meshwork (TM | investigated the function of miR-126-5p in human trabecular | meshwork cells (TMCs) under chronic oxidative stress (COS | Chronic oxidative stress (COS) is related to | ) in glaucoma. MicroRNAs (miRNAs) have a key role in

关键词： Glaucoma | miR-126-5p | PI3K/AKT pathway | HSPB8

摘要： expression profile of CRs in trabecular meshwork (TM | human trabecular meshwork cell (HTMC) oxidative stress | AimsThis research aims to establish a | chromatin regulator (CR) signature to provide new | epigenetic insights into the pathogenesis of primary open

关键词： Glaucoma | POAG | chromatin regulators | trabecular meshwork | oxidative stress

摘要：). Methods Human trabecular meshwork (TM) cells were | risk of bleeding from the trabecular meshwork and | Purpose To investigate the antifibrotic and | vasoconstrictor effects of adrenaline in Schlemm's canal and | suprachoroidal minimally invasive glaucoma surgery (MIGS

关键词： Glaucoma | Adrenaline | Fibrosis | MIGS

摘要： trabecular meshwork bypass stent to present to the ED with | glaucoma surgery. Trabecular meshwork bypass stent, but | not trabecular meshwork excision and/or Schlemm | Purpose: To describe the frequency, findings | , and interventions of patients' emergency department

关键词： Emergency department | Glaucoma surgery | Postoperative

摘要： implants on cell viability in human trabecular meshwork | trabecular cells. This study shows proof of concept that | Timolol maleate (TML) is a beta-blocker drug | that is commonly used to lower the intraocular | pressure in glaucoma. This study focused on using a 3D

关键词： Glaucoma | Timolol | 3D printing | Drug-eluting implants | Sustained-release

摘要： targeting trabecular meshwork function, neuroprotection | IntroductionGlaucoma is a neurodegenerative | disease that causes irreversible blindness worldwide. It | results from retinal ganglion cell (RGC) loss and | progressive optic nerve damage, mainly associated with

关键词： Adenosine | brimonidine | glaucoma | nanoformulation | neuroprotection | nutrients

摘要： human trabecular meshwork cells in response to CMV | Virus-induced trabeculitis is considered a | significant cause of uveitic glaucoma, being marked by a | sudden increase in intraocular pressure and relatively | mild inflammation in the anterior chamber of the eye

关键词： Liver X receptor | Cytomegalovirus | Uveitic glaucoma

摘要： trabecular meshwork (TM) to decrease intraocular pressure | ObjectivesFemtosecond laser image guided high | precision trabeculotomy (FLigHT) is a novel open-angle | glaucoma treatment. The procedure non-invasively creates | aqueous humor (AH) drainage channel from the anterior

关键词： aqueous humor | femtosecond laser trabeculotomy | finite element modeling | intraocular pressure | open-angle glaucoma

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： ferroptosis in human trabecular* meshwork cells (HTMCs* | extracellular matrix (ECM) deposition in the trabecular | meshwork (TM). Transmembrane and coiled-coil domain | Glaucoma, a leading cause of global blindness | , is marked by irreversible retinal ganglion cells

摘要： the pathophysiology of the trabecular* meshwork (TM* | investigated the function of miR-126-5p in human trabecular | meshwork cells (TMCs) under chronic oxidative stress (COS | Chronic oxidative stress (COS) is related to | ) in glaucoma. MicroRNAs (miRNAs) have a key role in

摘要： expression profile of CRs in trabecular* meshwork (TM* | human trabecular* meshwork cell (HTMC) oxidative stress* | AimsThis research aims to establish a | chromatin regulator (CR) signature to provide new | epigenetic insights into the pathogenesis of primary open

摘要：). Methods Human trabecular* meshwork (TM) cells were* | risk of bleeding from the trabecular* meshwork and* | Purpose To investigate the antifibrotic and | vasoconstrictor effects of adrenaline in Schlemm's canal and | suprachoroidal minimally invasive glaucoma surgery (MIGS

摘要： trabecular meshwork bypass stent to present to the ED with | glaucoma surgery. Trabecular* meshwork bypass stent, but* | not trabecular* meshwork excision and/or Schlemm* | Purpose: To describe the frequency, findings | , and interventions of patients' emergency department

摘要： targeting trabecular* meshwork function, neuroprotection* | IntroductionGlaucoma is a neurodegenerative | disease that causes irreversible blindness worldwide. It | results from retinal ganglion cell (RGC) loss and | progressive optic nerve damage, mainly associated with

摘要： human trabecular* meshwork cells in response to CMV* | Virus-induced trabeculitis is considered a | significant cause of uveitic glaucoma, being marked by a | sudden increase in intraocular pressure and relatively | mild inflammation in the anterior chamber of the eye