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1. Unveiling the metabolomic profile of growth hormone deficiency children using NMR spectroscopy NSTL国家科技图书文献中心

Eftychia A.,Aggelaki |  Aristeidis,Giannakop...... -  《Metabolomics》 - 2025,21(1) - Article: 25~Article: 25 - 共13页

摘要: GHD. Plasma, serum, and urine samples were collected |  that metabolome plays a pivotal role in GHD, but | Abstract Introduction The diagnosis of Growth |  Hormone Deficiency (GHD) during childhood has been the |  subject of much controversy over the last few years
关键词: Growth hormone deficiency |  Metabolomics |  NMR spectroscopy |  IGF-1

2. 5-Aminolevulinate acid improves boar semen quality by enhancing the sperm mitochondrial function NSTL国家科技图书文献中心

Wang, Shanpeng |  Wang, Qi... -  《Theriogenology》 - 2025,239 - 共15页

摘要: mg/kg/d). After nine weeks of treatment, serum and |  serum testosterone levels. Metabolomic analysis |  boar semen quality by enhancing seminal plasma |  metabolome, sperm mitochondrial function and overall | 5-Aminolevulinic acid (5-ALA) is a crucial
关键词: Boars |  Fertility |  Mitochondrial protein |  Semen quality

3. Plasma Instead of Serum Avoids Critical Confounding of Clinical Metabolomics Studies by Platelets NSTL国家科技图书文献中心

Hagn, Gerhard |  Meier-Menches, Samue...... -  《Journal of proteome research》 - 2024,23(8) - 3064~3075 - 共12页 - 被引量:1

摘要: serum compared to plasma. A prospective, randomized |  the serum metabolome may be substantially confounded |  bioanalytical method supporting clinical investigations. Serum |  and plasma are commonly used without rational |  prioritization. Serum is collected after blood coagulation, a
关键词: acetylsalicylic acid |  clinical metabolomics |  confounders |  serum |  drug effects |  lipidmediators |  metabolomics |  omega-3 fatty acids |  plasma |  platelets...

4. Metabolic signatures of population exposure to metal mixtures: A metabolome-wide association study NSTL国家科技图书文献中心

Wu L. |  Xin Y.... -  《Environmental Pollution》 - 2024,360(Nov.) - 1.1~1.7 - 共7页

摘要: concentrations of 23 metal elements. The serum metabolome was |  to assess the serum metabolic signatures of people |  exposed to metal mixtures. Serum and urine samples were | , China, in September 2019. Inductively coupled plasma | -MS). A metabolome-wide association study (MWAS) was
关键词: Metal mixture effect |  MWAS |  Quantile g-computation |  Serum metabolome

5. Unraveling the potential of segment scan mass spectral acquisition for chemical isotope labeling LC-MS-based metabolome analysis: Performance assessment across different types of biological samples NSTL国家科技图书文献中心

Wang, Chu-Fan |  Li, Liang -  《Analytica chimica acta》 - 2024,1288 - ARTN 342137~ - 共9页

摘要:, serum/ plasma, cell/tissue extracts, saliva, etc.), we | -MS is a powerful tool for metabolome analysis with |  scan method for metabolome analysis of different |  for CIL LC-Orbitrap-MS-based metabolome analysis of | Background: Chemical isotope labeling (CIL) LC
关键词: Metabolomics |  Chemical isotope labeling |  Orbitrap MS |  Segment scan |  Metabolic complexity |  DYNAMIC-RANGE |  SPECTROMETRY

6. A metabolomic perspective on the mechanisms by which environmental pollutants and lifestyle lead to male infertility NSTL国家科技图书文献中心

Wen Yang |  Rong Hua... -  《Andrology》 - 2024,12(4) - 719~739 - 共21页 - 被引量:3

摘要: the metabolites in serum, seminal plasma, urine |  metabolome, the related metabolic pathways, and the |  metabolic landscape of semen and seminal plasma in general |  differences in semen and seminal plasma biomarkers between | Abstract The incidence of male infertility (MI
关键词: biomarkers |  male infertility (MI) |  metabolic profiling |  metabolomics |  MI pathogenesis |  non‐genetic factors

7. Multi-dimensional metabolomic profiling reveals dysregulated ornithine metabolism hallmarks associated with a severe acute pancreatitis phenotype NSTL国家科技图书文献中心

Yang, Jinxi |  Shi, Na... -  《Translational research: the journal of laboratory and clinical medicine》 - 2024,263 - 28~44 - 共17页 - 被引量:1

摘要: inflammatory process. The plasma metabolome of AP patients is |  targeted metabolomics was used to analyze plasma samples |  determination of serum and pancreatic tissue metabolic | To reveal dysregulated metabolism hallmark |  that was associated with a severe acute pancreatitis
关键词: Targeted metabolomics |  Mass spectrometry imaging |  Severe acute pancreatitis |  Ornithine metabolism |  Arginase2 |  C-REACTIVE PROTEIN |  BASIC-AMINO-ACIDS |  L-ARGININE |  INFLAMMATION |  ACTIVATION...

8. Using Machine Learning to Construct the Blood-Follicle Distribution Models of Various Trace Elements and Explore the Transport-Related Pathways with Multiomics Data NSTL国家科技图书文献中心

Guohuan Zhang |  Weinan Lin... -  《Environmental Science & Technology: ES&T》 - 2024,58(18) - 7743~7757 - 共15页 - 被引量:2

摘要: both serum and follicular fluid (FF) samples from the |  features of the metabolome, lipidome, and proteome in |  both plasma and FF samples. Multiomics features |  serum with transfer efficiencies of 1.19-4.38, while a |  serum levels with a random forest model.
关键词: blood-follicle barrier |  trace elements |  multiomics |  machine learning

9. A novel endogenous retention-index for minimizing retention-time variations in metabolomic analysis with reversed-phase ultrahigh-performance liquid-chromatography and mass spectrometry NSTL国家科技图书文献中心

Chen, Qinsheng |  Lu, Qinwei... -  《Talanta: The International Journal of Pure and Applied Analytical Chemistry》 - 2024,268(Pt.1) - ARTN 125318~ - 共6页

摘要: matrices including human serum, plasma, fecal, urine |  min for most metabolites in a model metabolome | Consistent retention time (tR) of metabolites |  is vital for identification in metabolomic analysis |  with ultrahighperformance liquid-chromatography (UPLC
关键词: Straight-chain acylcarnitines |  Endogenous retention-index |  Metabonomics/metabolomics |  Ultrahigh-performance liquid-chromatography-mass spectrometry |  Metabolic profiling |  ACYLCARNITINES |  ANNOTATION |  METLIN

10. Mild processing and addition of milk fat globule membrane in infant formula may better mimic intragastric behavior of human milk: A proof of concept trial in healthy males NSTL国家科技图书文献中心

Roelofs, Julia J. M. |  Tjoelker, Reina S.... -  《Food hydrocolloids》 - 2024,151(Jun.) - 1.1~1.8 - 共8页 - 被引量:1

摘要: postprandial plasma metabolome of an experimental minimally |  differ. EF yielded higher serum concentrations of | Background: During breastfeeding the |  macronutrient composition of breastmilk changes gradually from |  relatively low-fat (foremilk) to relatively high-fat
关键词: Infant formula |  Emulsion stability |  Gastric behavior |  Digestion |  MRI
检索条件plasma serum metabolome

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