NSTL国家科技图书文献中心

1. Levetiracetam pharmacokinetics in venovenous extracorporeal membrane oxygenation: A case report NSTL国家科技图书文献中心

Solomon, Diana | Gaines, Devon ... - 《Perfusion》 - 2025,40(4) - 1041～1044 - 共4页

摘要： pharmacokinetics of levetiracetam in a critically ill patient | membrane oxygenation on the pharmacokinetics* of this* | literature describing the pharmacokinetics* of medications* | This case report describes the | supported on venovenous membrane oxygenation. While

关键词： extracorporeal membrane oxygenation | pharmacokinetics | levetiracetam

2. Concerns Regarding the Use of Kirchhoff’s Laws in Pharmacokinetics NSTL国家科技图书文献中心

Svein,Øie - 《AAPS PharmSciTech》 - 2025,26(1) - Article: 30～Article: 30 - 共7页

摘要： voltage laws also pertain to pharmacokinetics* (1–3). It* | translations of the Kirchhoff’s Laws to pharmacokinetics. | Abstract Over the last two years the idea that | the principles presented in Kirchhoff’s circuit and | is claimed that these principles make the

关键词： bioavailability | clearance | Kirchhoff’s Laws | pharmacokinetics

3. Population pharmacokinetics of bedaquiline: a systematic review NSTL国家科技图书文献中心

Jin, Jie | Cao, Jie ... - 《European journal of clinical pharmacology》 - 2025,81(3) - 347～363 - 共17页

摘要： inception to October 1, 2023. Population pharmacokinetics | Background and objectivesBedaquiline (BDQ | ) plays a critical role in the treatment of multidrug | -resistant tuberculosis (MDR-TB). However, the large | pharmacokinetic (PK) variability of BDQ presents a significant

关键词： Multidrug-resistant tuberculosis | Bedaquiline | Population pharmacokinetics | Individualized dose adjustment | Nonlinear mixed-effects model

4. Pharmacokinetics of Enrofloxacin and Its Metabolite Ciprofloxacin in Nanyang Cattle NSTL国家科技图书文献中心

Yang, Fang | Sun, Long-Ji ... - 《Journal of Veterinary Pharmacology and Therapeutics》 - 2025,48(1) - 30～36 - 共7页

摘要： the pharmacokinetics* of enrofloxacin and its* | The objective of this study was to determine | metabolite, ciprofloxacin, in Nanyang cattle after a single | intravenous (IV), and intramuscular (IM) administration of | enrofloxacin at 2.5 mg/kg body weight (BW). Blood samples

关键词： ciprofloxacin | enrofloxacin | HPLC | Nanyang cattle | pharmacokinetics

5. Inorganic mercury pharmacokinetics in man: a hybrid model NSTL国家科技图书文献中心

Farris, Fred | Awaness, Ayda ... - 《Xenobiotica》 - 2025,55(1) - 4～15 - 共12页

摘要： simulates inorganic mercury [Hg(II)] pharmacokinetics* in* | A four-compartment model is presented that | blood, tissue, and excreta over a 70-day period | . Simulations are validated against data collected from five | human subjects, and previously analyzed.In the model

关键词： Mercury | inorganic mercury | pharmacokinetics, hybrid model | multicompartment model | mercury transport

6. Multiorgan-on-a-chip for cancer drug pharmacokinetics-pharmacodynamics (PK-PD) modeling and simulations NSTL国家科技图书文献中心

Mohammed, Abdurehman... | Kurucaovali, Filiz ... - 《Journal of pharmacokinetics and pharmacodynamics》 - 2025,52(1) - Article: 1～Article: 1 - 共13页

摘要： generate pharmacokinetics* (PK) data. The PK and PD data* | Cancer is one of the most common and fatal | diseases worldwide and kills millions of people every | year. Cancer drug resistance, lack of efficacy, and | safety are significant problems in cancer patients. A

关键词： Multiorgan-on-a-chip | Breast cancer | Pharmacometrics | Pharmacokinetics | Pharmacodynamics | Safety | Efficacy

7. Studying the Influence of Ischemic Liver Damage on the Pharmacokinetics of a Phenolic Antioxidant NSTL国家科技图书文献中心

Yanovskaya, E. A. | Frelikh, G. A.... - 《Bulletin of experimental biology and medicine》 - 2025,178(3) - 323～326 - 共4页

摘要： pharmacokinetics of 2,6-diisobornyl-4-methylphenol, a phenolic | pharmacokinetics. Analysis of actual blood plasma samples | : changes in the pharmacokinetics* of the phenolic* | A new approach has been developed to study the | antioxidant, after intragastric administration at a dose of

关键词： pharmacokinetics | ischemia/reperfusion | liver | 2,6-diisobornyl-4-methylphenol | catheterization

8. Unveiling the Essence of Isoliquiritigenin: Exploring Its Chemistry, Pharmacokinetics, and Pharmacological Potential NSTL国家科技图书文献中心

Nihal, P. Mohamed | Mohapatra, Debasish ... - 《Chemistry Africa》 - 2025,8(1) - 23～42 - 共20页

摘要：, structure-activity relationships (SAR), pharmacokinetics | meticulously elucidated. Insights into its pharmacokinetics | chemistry, pharmacokinetics, and mode of action enriches | Isoliquiritigenin (ISL), a prominent chalcone | -type flavonoid primarily derived from liquorice roots

关键词： Isoliquiritigenin | Chemistry | Pharmacokinetics | Pharmacology | Cancer | Molecular targets

9. Pharmacokinetics of islatravir in participants with moderate hepatic impairment NSTL国家科技图书文献中心

Matthews, Randolph P... | Patel, Munjal ... - 《Antimicrobial agents and chemotherapy.》 - 2025,69(4) - e0155324～e0155324 - 共10页

摘要：; thus, ISL pharmacokinetics* (PK) may be affected by* | Islatravir (ISL) is a nucleoside reverse | transcriptase translocation inhibitor in development for the | treatment of HIV-1 infection. People living with HIV are | at risk of liver disease. ISL is metabolized by

关键词： islatravir | pharmacokinetics | human immunodeficiency virus | hepatic impairment | liver disease

10. Pharmacokinetics after bariatric surgery: adverse effects and drug safety issues in bariatric patients NSTL国家科技图书文献中心

Porat, Daniel | Dahan, Arik - 《Expert review of clinical pharmacology》 - 2025,18(3) - 101～108 - 共8页

摘要： may impact oral drug absorption/pharmacokinetics | absorption/pharmacokinetics, leading to potential treatment | pharmacokinetics and risk of adverse effects. Among them | altered post-bariatric pharmacokinetics* of various drugs* | Introduction: Medication management after

摘要： pharmacokinetics of levetiracetam in a critically ill patient | membrane oxygenation on the pharmacokinetics* of this* | literature describing the pharmacokinetics* of medications* | This case report describes the | supported on venovenous membrane oxygenation. While

关键词： extracorporeal membrane oxygenation | pharmacokinetics | levetiracetam

摘要： voltage laws also pertain to pharmacokinetics* (1–3). It* | translations of the Kirchhoff’s Laws to pharmacokinetics. | Abstract Over the last two years the idea that | the principles presented in Kirchhoff’s circuit and | is claimed that these principles make the

关键词： bioavailability | clearance | Kirchhoff’s Laws | pharmacokinetics

摘要： inception to October 1, 2023. Population pharmacokinetics | Background and objectivesBedaquiline (BDQ | ) plays a critical role in the treatment of multidrug | -resistant tuberculosis (MDR-TB). However, the large | pharmacokinetic (PK) variability of BDQ presents a significant

关键词： Multidrug-resistant tuberculosis | Bedaquiline | Population pharmacokinetics | Individualized dose adjustment | Nonlinear mixed-effects model

摘要： the pharmacokinetics* of enrofloxacin and its* | The objective of this study was to determine | metabolite, ciprofloxacin, in Nanyang cattle after a single | intravenous (IV), and intramuscular (IM) administration of | enrofloxacin at 2.5 mg/kg body weight (BW). Blood samples

关键词： ciprofloxacin | enrofloxacin | HPLC | Nanyang cattle | pharmacokinetics

摘要： simulates inorganic mercury [Hg(II)] pharmacokinetics* in* | A four-compartment model is presented that | blood, tissue, and excreta over a 70-day period | . Simulations are validated against data collected from five | human subjects, and previously analyzed.In the model

关键词： Mercury | inorganic mercury | pharmacokinetics, hybrid model | multicompartment model | mercury transport

摘要： generate pharmacokinetics* (PK) data. The PK and PD data* | Cancer is one of the most common and fatal | diseases worldwide and kills millions of people every | year. Cancer drug resistance, lack of efficacy, and | safety are significant problems in cancer patients. A

关键词： Multiorgan-on-a-chip | Breast cancer | Pharmacometrics | Pharmacokinetics | Pharmacodynamics | Safety | Efficacy

摘要： pharmacokinetics of 2,6-diisobornyl-4-methylphenol, a phenolic | pharmacokinetics. Analysis of actual blood plasma samples | : changes in the pharmacokinetics* of the phenolic* | A new approach has been developed to study the | antioxidant, after intragastric administration at a dose of

关键词： pharmacokinetics | ischemia/reperfusion | liver | 2,6-diisobornyl-4-methylphenol | catheterization

摘要：, structure-activity relationships (SAR), pharmacokinetics | meticulously elucidated. Insights into its pharmacokinetics | chemistry, pharmacokinetics, and mode of action enriches | Isoliquiritigenin (ISL), a prominent chalcone | -type flavonoid primarily derived from liquorice roots

关键词： Isoliquiritigenin | Chemistry | Pharmacokinetics | Pharmacology | Cancer | Molecular targets

摘要：; thus, ISL pharmacokinetics* (PK) may be affected by* | Islatravir (ISL) is a nucleoside reverse | transcriptase translocation inhibitor in development for the | treatment of HIV-1 infection. People living with HIV are | at risk of liver disease. ISL is metabolized by

关键词： islatravir | pharmacokinetics | human immunodeficiency virus | hepatic impairment | liver disease

摘要： may impact oral drug absorption/pharmacokinetics | absorption/pharmacokinetics, leading to potential treatment | pharmacokinetics and risk of adverse effects. Among them | altered post-bariatric pharmacokinetics* of various drugs* | Introduction: Medication management after

关键词： Bariatric surgery | biopharmaceutics | drug safety | pharmacokinetics | pharmacotherapy | oral absorption

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： pharmacokinetics of levetiracetam in a critically ill patient | membrane oxygenation on the pharmacokinetics of this | literature describing the pharmacokinetics of medications | This case report describes the | supported on venovenous membrane oxygenation. While

关键词： extracorporeal membrane oxygenation | pharmacokinetics | levetiracetam

摘要： voltage laws also pertain to pharmacokinetics (1–3). It | translations of the Kirchhoff’s Laws to pharmacokinetics. | Abstract Over the last two years the idea that | the principles presented in Kirchhoff’s circuit and | is claimed that these principles make the

关键词： bioavailability | clearance | Kirchhoff’s Laws | pharmacokinetics

摘要： inception to October 1, 2023. Population pharmacokinetics | Background and objectivesBedaquiline (BDQ | ) plays a critical role in the treatment of multidrug | -resistant tuberculosis (MDR-TB). However, the large | pharmacokinetic (PK) variability of BDQ presents a significant

关键词： Multidrug-resistant tuberculosis | Bedaquiline | Population pharmacokinetics | Individualized dose adjustment | Nonlinear mixed-effects model

摘要： the pharmacokinetics of enrofloxacin and its | The objective of this study was to determine | metabolite, ciprofloxacin, in Nanyang cattle after a single | intravenous (IV), and intramuscular (IM) administration of | enrofloxacin at 2.5 mg/kg body weight (BW). Blood samples

关键词： ciprofloxacin | enrofloxacin | HPLC | Nanyang cattle | pharmacokinetics

摘要： simulates inorganic mercury [Hg(II)] pharmacokinetics in | A four-compartment model is presented that | blood, tissue, and excreta over a 70-day period | . Simulations are validated against data collected from five | human subjects, and previously analyzed.In the model

关键词： Mercury | inorganic mercury | pharmacokinetics, hybrid model | multicompartment model | mercury transport

摘要： generate pharmacokinetics (PK) data. The PK and PD data | Cancer is one of the most common and fatal | diseases worldwide and kills millions of people every | year. Cancer drug resistance, lack of efficacy, and | safety are significant problems in cancer patients. A

关键词： Multiorgan-on-a-chip | Breast cancer | Pharmacometrics | Pharmacokinetics | Pharmacodynamics | Safety | Efficacy

摘要： pharmacokinetics of 2,6-diisobornyl-4-methylphenol, a phenolic | pharmacokinetics. Analysis of actual blood plasma samples | : changes in the pharmacokinetics of the phenolic | A new approach has been developed to study the | antioxidant, after intragastric administration at a dose of

关键词： pharmacokinetics | ischemia/reperfusion | liver | 2,6-diisobornyl-4-methylphenol | catheterization

摘要：, structure-activity relationships (SAR), pharmacokinetics | meticulously elucidated. Insights into its pharmacokinetics | chemistry, pharmacokinetics, and mode of action enriches | Isoliquiritigenin (ISL), a prominent chalcone | -type flavonoid primarily derived from liquorice roots

关键词： Isoliquiritigenin | Chemistry | Pharmacokinetics | Pharmacology | Cancer | Molecular targets

摘要：; thus, ISL pharmacokinetics (PK) may be affected by | Islatravir (ISL) is a nucleoside reverse | transcriptase translocation inhibitor in development for the | treatment of HIV-1 infection. People living with HIV are | at risk of liver disease. ISL is metabolized by

关键词： islatravir | pharmacokinetics | human immunodeficiency virus | hepatic impairment | liver disease

摘要： may impact oral drug absorption/pharmacokinetics | absorption/pharmacokinetics, leading to potential treatment | pharmacokinetics and risk of adverse effects. Among them | altered post-bariatric pharmacokinetics of various drugs | Introduction: Medication management after

关键词： Bariatric surgery | biopharmaceutics | drug safety | pharmacokinetics | pharmacotherapy | oral absorption

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： pharmacokinetics of levetiracetam in a critically ill patient | membrane oxygenation on the pharmacokinetics* of this* | literature describing the pharmacokinetics* of medications* | This case report describes the | supported on venovenous membrane oxygenation. While

摘要： voltage laws also pertain to pharmacokinetics* (1–3). It* | translations of the Kirchhoff’s Laws to pharmacokinetics. | Abstract Over the last two years the idea that | the principles presented in Kirchhoff’s circuit and | is claimed that these principles make the

摘要： the pharmacokinetics* of enrofloxacin and its* | The objective of this study was to determine | metabolite, ciprofloxacin, in Nanyang cattle after a single | intravenous (IV), and intramuscular (IM) administration of | enrofloxacin at 2.5 mg/kg body weight (BW). Blood samples

摘要： simulates inorganic mercury [Hg(II)] pharmacokinetics* in* | A four-compartment model is presented that | blood, tissue, and excreta over a 70-day period | . Simulations are validated against data collected from five | human subjects, and previously analyzed.In the model

摘要： generate pharmacokinetics* (PK) data. The PK and PD data* | Cancer is one of the most common and fatal | diseases worldwide and kills millions of people every | year. Cancer drug resistance, lack of efficacy, and | safety are significant problems in cancer patients. A

摘要： pharmacokinetics of 2,6-diisobornyl-4-methylphenol, a phenolic | pharmacokinetics. Analysis of actual blood plasma samples | : changes in the pharmacokinetics* of the phenolic* | A new approach has been developed to study the | antioxidant, after intragastric administration at a dose of

摘要：; thus, ISL pharmacokinetics* (PK) may be affected by* | Islatravir (ISL) is a nucleoside reverse | transcriptase translocation inhibitor in development for the | treatment of HIV-1 infection. People living with HIV are | at risk of liver disease. ISL is metabolized by

摘要： may impact oral drug absorption/pharmacokinetics | absorption/pharmacokinetics, leading to potential treatment | pharmacokinetics and risk of adverse effects. Among them | altered post-bariatric pharmacokinetics* of various drugs* | Introduction: Medication management after