NSTL国家科技图书文献中心

1. DNA Phosphorothioate Modification Systems and Associated Phage Defense Systems NSTL国家科技图书文献中心

Wang, Lianrong | Tang, Yaqian ... - 《Annual Review of Microbiology》 - 2024,78 - 447～462 - 共16页

摘要： modification-associated defense* systems. We also describe* | notable applications of PT systems* in the engineering of* | phage-resistant bacterial strains, RNA editing, and | In contrast to the well-known DNA methylation | of nucleobases, DNA phosphorothioate (PT

关键词： DNA phosphorothioate modification | DNA PT modification | DndFGH | SspE | ScoMcrA | phage-resistant strains | sulfur-binding domain

2. Genomic insights into the phage-defense systems of Stenotrophomonas maltophilia clinical isolates NSTL国家科技图书文献中心

Zhuang Z. | Cheng Y.-Y.... - 《Microbiological Research》 - 2024,278 - 共12页 - 被引量：1

摘要： the phage* defense systems. To systematically | in relation to phage-defense mechanisms, which* | immunocompromised patients. Although phage* therapy is one of* | main challenges of phage* therapeutics include* | accumulation of phage* resistant mutations and acquisition of*

关键词： Pan-immunity | Phage-defense | Prophage | Stenotrophomonas maltophilia | Virulence

3. Bacterial defense systems exhibit synergistic anti-phage activity NSTL国家科技图书文献中心

Wu, Yi | Garushyants, Sofya K...... - 《Cell Host & Microbe》 - 2024,32(4) - 共23页 - 被引量：14

摘要：Bacterial defense* against phage predation* | involves diverse defense* systems acting individually and* | . We investigated >100 defense* systems in 42,925* | association. For several pairs of defense systems | -phage* activity. Some defense system pairs that are*

关键词： GENE-TRANSFER | ANTIVIRAL DEFENSE | R PACKAGE | RESTRICTION | BIOLOGY | CLASSIFICATION | ENDONUCLEASE | ORGANIZATION | MECHANISM | SEQUENCE

4. Bacterial homologs of innate eukaryotic antiviral defenses with anti-phage activity highlight shared evolutionary roots of viral defenses NSTL国家科技图书文献中心

van den Berg, Daan F... | Costa, Ana Rita ... - 《Cell Host & Microbe》 - 2024,32(8) - 共26页

摘要： defense systems to protect against phage predation. Some | phage defense systems related to innate antiviral | antiviral defense* systems onto prokaryotic genomes, using* | defense systems, including factors preventing viral | . Collectively, these defense systems* support the concept of*

关键词： DNA-BINDING | WEB SERVER | CLUSTAL-W | INOSITOL | ALIGNMENT | DOMAINS | GENE | MONOPHOSPHATASE | IDENTIFICATION | VISUALIZATION

5. RNA-based regulation in bacteria-phage interactions NSTL国家科技图书文献中心

Saunier M. | Fortier L.-C.... - 《Anaerobe》 - 2024,87 - 102851～102851 - 共6页 - 被引量：2

摘要： components of several anti-phage* defense systems in* | -phage* defense systems are largely discussed. Newly* | discovered defense* systems such as retrons and CBASS* | -recognized regulatory roles in crossroad of phage-bacteria | -phage* interactions with a particular focus on*

关键词： Abortive infection | Anti-Phage defense | Clostridioides difficile | CRISPR-Cas | Prophages | Regulatory RNAs | Toxin-antitoxin

6. Strategic combination of bacteriophages with highly susceptible cells for enhanced intestinal settlement and resistant cell killing NSTL国家科技图书文献中心

Ha, Eun-Jin | Hong, Seung-Min ... - 《Biochemical and Biophysical Research Communications》 - 2024,709 - 共6页

摘要： defense systems carried on mobile genetic elements | defense systems, exhibiting considerable resistance to | (phage) therapy has been successful in controlling MDR | , but phage-resistant variants have rapidly emerged | through the horizontal transmission of diverse phage

关键词： O78 serogroup avian pathogenic E. coli | Bacteriophage therapy | Phage susceptibility | Phage shedding | Enhanced resistance cell killing

7. Molecular basis of Gabija anti-phage supramolecular assemblies NSTL国家科技图书文献中心

Xiao-Yuan Yang | Zhangfei Shen ... - 《Nature structural & molecular biology》 - 2024,31(8) - 1243～1250 - 共8页 - 被引量：4

摘要： defense systems in prokaryotes, Gabija consists of a | supramolecular complex for anti-phage* defense. Further* | As one of the most prevalent anti-phage | study defines a framework for understanding anti-phage | immune defense* by the GajAB complex.*

关键词： prevalent | anti-phage | defense

8. Phage fibers and spikes: a nanoscale Swiss army knife for host infection NSTL国家科技图书文献中心

Ouyang, Ruochen | Ongenae, Veronique ... - 《Current opinion in microbiology》 - 2024,77 - ARTN 102429～ - 共7页 - 被引量：4

摘要： phage defense systems, initially determined by the | . However, finding a suitable phage* relies on numerous* | infection cycle. The host range of a phage* is, besides* | fundamental mechanisms during phage* infection. In this* | different phage* tail and head fibers, spike models, and*

关键词： BACTERIOPHAGE | ADSORPTION | MOTILITY | FLAGELLA | PROTEINS | PBS1

9. A Vibrio cholerae Type IV restriction system targets glucosylated 5-hydroxymethylcytosine to protect against phage infection NSTL国家科技图书文献中心

Jasper B. Gomez | Christopher M. Water... - 《Journal of bacteriology.》 - 2024,206(9) - e0014324～e0014324 - 共19页

摘要： evolved a myriad of phage* defense systems. Although | several novel defense systems have been discovered, we* | this region is a phage* defense island. Our study* | evolutionary interplay between restriction systems and phage | defense systems. Some of these systems specifically

关键词： Vibrio cholerae | phage | restriction | modification | Type IV

10. The vibriophage-encoded inhibitor OrbA abrogates BREX-mediated defense through the ATPase BrxC NSTL国家科技图书文献中心

Reid T. Oshiro | Drew T. Dunham ... - 《Journal of bacteriology.》 - 2024,206(11) - e0020624～e0020624 - 共6页

摘要： interrogate how defense* systems function. A relatively* | defense systems using different | defense systems, as they are powerful tools for | to restrict the proliferation of the other. Phage | -encoded defense* inhibitors have proven powerful tools to*

摘要： modification-associated defense* systems. We also describe* | notable applications of PT systems* in the engineering of* | phage-resistant bacterial strains, RNA editing, and | In contrast to the well-known DNA methylation | of nucleobases, DNA phosphorothioate (PT

关键词： DNA phosphorothioate modification | DNA PT modification | DndFGH | SspE | ScoMcrA | phage-resistant strains | sulfur-binding domain

摘要： the phage* defense systems. To systematically | in relation to phage-defense mechanisms, which* | immunocompromised patients. Although phage* therapy is one of* | main challenges of phage* therapeutics include* | accumulation of phage* resistant mutations and acquisition of*

关键词： Pan-immunity | Phage-defense | Prophage | Stenotrophomonas maltophilia | Virulence

摘要：Bacterial defense* against phage predation* | involves diverse defense* systems acting individually and* | . We investigated >100 defense* systems in 42,925* | association. For several pairs of defense systems | -phage* activity. Some defense system pairs that are*

关键词： GENE-TRANSFER | ANTIVIRAL DEFENSE | R PACKAGE | RESTRICTION | BIOLOGY | CLASSIFICATION | ENDONUCLEASE | ORGANIZATION | MECHANISM | SEQUENCE

摘要： defense systems to protect against phage predation. Some | phage defense systems related to innate antiviral | antiviral defense* systems onto prokaryotic genomes, using* | defense systems, including factors preventing viral | . Collectively, these defense systems* support the concept of*

关键词： DNA-BINDING | WEB SERVER | CLUSTAL-W | INOSITOL | ALIGNMENT | DOMAINS | GENE | MONOPHOSPHATASE | IDENTIFICATION | VISUALIZATION

摘要： components of several anti-phage* defense systems in* | -phage* defense systems are largely discussed. Newly* | discovered defense* systems such as retrons and CBASS* | -recognized regulatory roles in crossroad of phage-bacteria | -phage* interactions with a particular focus on*

关键词： Abortive infection | Anti-Phage defense | Clostridioides difficile | CRISPR-Cas | Prophages | Regulatory RNAs | Toxin-antitoxin

摘要： defense systems carried on mobile genetic elements | defense systems, exhibiting considerable resistance to | (phage) therapy has been successful in controlling MDR | , but phage-resistant variants have rapidly emerged | through the horizontal transmission of diverse phage

关键词： O78 serogroup avian pathogenic E. coli | Bacteriophage therapy | Phage susceptibility | Phage shedding | Enhanced resistance cell killing

摘要： defense systems in prokaryotes, Gabija consists of a | supramolecular complex for anti-phage* defense. Further* | As one of the most prevalent anti-phage | study defines a framework for understanding anti-phage | immune defense* by the GajAB complex.*

关键词： prevalent | anti-phage | defense

摘要： phage defense systems, initially determined by the | . However, finding a suitable phage* relies on numerous* | infection cycle. The host range of a phage* is, besides* | fundamental mechanisms during phage* infection. In this* | different phage* tail and head fibers, spike models, and*

关键词： BACTERIOPHAGE | ADSORPTION | MOTILITY | FLAGELLA | PROTEINS | PBS1

摘要： evolved a myriad of phage* defense systems. Although | several novel defense systems have been discovered, we* | this region is a phage* defense island. Our study* | evolutionary interplay between restriction systems and phage | defense systems. Some of these systems specifically

关键词： Vibrio cholerae | phage | restriction | modification | Type IV

摘要： interrogate how defense* systems function. A relatively* | defense systems using different | defense systems, as they are powerful tools for | to restrict the proliferation of the other. Phage | -encoded defense* inhibitors have proven powerful tools to*

关键词： BREX | Vibrio cholerae | counterdefense | phage defense.

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： modification-associated defense systems. We also describe | notable applications of PT systems in the engineering of | phage-resistant bacterial strains, RNA editing, and | In contrast to the well-known DNA methylation | of nucleobases, DNA phosphorothioate (PT

关键词： DNA phosphorothioate modification | DNA PT modification | DndFGH | SspE | ScoMcrA | phage-resistant strains | sulfur-binding domain

摘要： the phage defense systems. To systematically | in relation to phage-defense mechanisms, which | immunocompromised patients. Although phage therapy is one of | main challenges of phage therapeutics include | accumulation of phage resistant mutations and acquisition of

关键词： Pan-immunity | Phage-defense | Prophage | Stenotrophomonas maltophilia | Virulence

摘要：Bacterial defense against phage predation | involves diverse defense systems acting individually and | . We investigated >100 defense systems in 42,925 | association. For several pairs of defense systems | -phage activity. Some defense system pairs that are

关键词： GENE-TRANSFER | ANTIVIRAL DEFENSE | R PACKAGE | RESTRICTION | BIOLOGY | CLASSIFICATION | ENDONUCLEASE | ORGANIZATION | MECHANISM | SEQUENCE

摘要： defense systems to protect against phage predation. Some | phage defense systems related to innate antiviral | antiviral defense systems onto prokaryotic genomes, using | defense systems, including factors preventing viral | . Collectively, these defense systems support the concept of

关键词： DNA-BINDING | WEB SERVER | CLUSTAL-W | INOSITOL | ALIGNMENT | DOMAINS | GENE | MONOPHOSPHATASE | IDENTIFICATION | VISUALIZATION

摘要： components of several anti-phage defense systems in | -phage defense systems are largely discussed. Newly | discovered defense systems such as retrons and CBASS | -recognized regulatory roles in crossroad of phage-bacteria | -phage interactions with a particular focus on

关键词： Abortive infection | Anti-Phage defense | Clostridioides difficile | CRISPR-Cas | Prophages | Regulatory RNAs | Toxin-antitoxin

摘要： defense systems carried on mobile genetic elements | defense systems, exhibiting considerable resistance to | (phage) therapy has been successful in controlling MDR | , but phage-resistant variants have rapidly emerged | through the horizontal transmission of diverse phage

关键词： O78 serogroup avian pathogenic E. coli | Bacteriophage therapy | Phage susceptibility | Phage shedding | Enhanced resistance cell killing

摘要： defense systems in prokaryotes, Gabija consists of a | supramolecular complex for anti-phage defense. Further | As one of the most prevalent anti-phage | study defines a framework for understanding anti-phage | immune defense by the GajAB complex.

关键词： prevalent | anti-phage | defense

摘要： phage defense systems, initially determined by the | . However, finding a suitable phage relies on numerous | infection cycle. The host range of a phage is, besides | fundamental mechanisms during phage infection. In this | different phage tail and head fibers, spike models, and

关键词： BACTERIOPHAGE | ADSORPTION | MOTILITY | FLAGELLA | PROTEINS | PBS1

摘要： evolved a myriad of phage defense systems. Although | several novel defense systems have been discovered, we | this region is a phage defense island. Our study | evolutionary interplay between restriction systems and phage | defense systems. Some of these systems specifically

关键词： Vibrio cholerae | phage | restriction | modification | Type IV

摘要： interrogate how defense systems function. A relatively | defense systems using different | defense systems, as they are powerful tools for | to restrict the proliferation of the other. Phage | -encoded defense inhibitors have proven powerful tools to

关键词： BREX | Vibrio cholerae | counterdefense | phage defense.

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： modification-associated defense* systems. We also describe* | notable applications of PT systems* in the engineering of* | phage-resistant bacterial strains, RNA editing, and | In contrast to the well-known DNA methylation | of nucleobases, DNA phosphorothioate (PT

摘要： the phage* defense systems. To systematically | in relation to phage-defense mechanisms, which* | immunocompromised patients. Although phage* therapy is one of* | main challenges of phage* therapeutics include* | accumulation of phage* resistant mutations and acquisition of*

摘要：Bacterial defense* against phage predation* | involves diverse defense* systems acting individually and* | . We investigated >100 defense* systems in 42,925* | association. For several pairs of defense systems | -phage* activity. Some defense system pairs that are*

摘要： defense systems to protect against phage predation. Some | phage defense systems related to innate antiviral | antiviral defense* systems onto prokaryotic genomes, using* | defense systems, including factors preventing viral | . Collectively, these defense systems* support the concept of*

摘要： components of several anti-phage* defense systems in* | -phage* defense systems are largely discussed. Newly* | discovered defense* systems such as retrons and CBASS* | -recognized regulatory roles in crossroad of phage-bacteria | -phage* interactions with a particular focus on*

摘要： defense systems in prokaryotes, Gabija consists of a | supramolecular complex for anti-phage* defense. Further* | As one of the most prevalent anti-phage | study defines a framework for understanding anti-phage | immune defense* by the GajAB complex.*

摘要： phage defense systems, initially determined by the | . However, finding a suitable phage* relies on numerous* | infection cycle. The host range of a phage* is, besides* | fundamental mechanisms during phage* infection. In this* | different phage* tail and head fibers, spike models, and*

摘要： evolved a myriad of phage* defense systems. Although | several novel defense systems have been discovered, we* | this region is a phage* defense island. Our study* | evolutionary interplay between restriction systems and phage | defense systems. Some of these systems specifically

摘要： interrogate how defense* systems function. A relatively* | defense systems using different | defense systems, as they are powerful tools for | to restrict the proliferation of the other. Phage | -encoded defense* inhibitors have proven powerful tools to*