Chelushkin, Pavel S. |  Leko, Maria V.... -  《Journal of peptide science: An official publication of the European Peptide Society》 - 2017,23(1) - 13～15 - 共3页 - 被引量：3

摘要：-steroid and peptide-polymer conjugates of model aminooxy |  technique is illustrated by the synthesis of peptide | -peptides. Copyright (C) 2016 European Peptide Society and | Oxime ligation is a powerful tool in various |  bioconjugation strategies. Nevertheless, high reaction rates

关键词： oxime ligation |  polymer-peptide conjugates |  peptide-steroids conjugates |  aminooxy-peptides

Lesma, Giordano |  Luraghi, Andrea... -  《Synthesis: International Journal of Methods in Synthetic Organic Chemistry》 - 2016,48(22) - 3907～3916 - 共10页 - 被引量：9

摘要： developed to access two different kinds of peptide | -ecdysteroid conjugates. The approach exploits the reactivity | An efficient multicomponent protocol has been |  of the 6-keto-7-ene group of 20-OH-ecdysone | , allowing the unprecedented preparation of 6-amino and 6

关键词： steroids |  peptide-steroid conjugates |  multicomponent reactions |  Ugi reaction |  multidrug resistance

Radell Echemendía |  Odette Concepción... -  《Tetrahedron》 - 2014,70(20) - 3297～3305 - 共9页 - 被引量：15

摘要： macrocyclic peptide-steroid conjugates featuring different |  preparation of novel triazole-linked peptide-steroid |  conjugates in good to excellent yields. The process |  relying on a sequential peptide coupling/CuAAC-based |  toward the future preparation of conjugates with

关键词： Steroids |  Peptide conjugates |  Click chemistry |  Peptidosteroids |  Conjugation

Rivera, D.G. |  Pérez-Labrada, K.... -  《Carbohydrate research》 - 2012,359 - 102～110 - 共9页 - 被引量：20

摘要： chimeras incorporating sugar, pseudo-peptide, and |  steroids. The approach proved wide substrate scope, as | -diosgenin conjugates resembling naturally occurring |  sugar/pseudo-peptide/steroid hybrids are produced | The one-pot synthesis of novel molecular

关键词： Carbohydrates |  Conjugation |  Hybrids |  Multicomponent reactions |  Steroids

Zhou SF |  Wang LL... -  《Current medicinal chemistry》 - 2008,15(20) - 1981～2039 - 共59页

摘要： conjugates) with different substrate specificity and |  sulfatidyl steroids. In vitro, the MRP/ABCC transporters |  oxyanions, peptide-based agents, and in concert with | Human contains 49 ATP-binding cassette (ABC | ) transporter genes and the multidrug resistance associated

关键词： MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1 GENE |  Human |  Multi-Drug Resistance |  蛋白质类

Rivera DG |  Pando O... -  《Tetrahedron》 - 2006,62(35) - 8327～8334 - 共8页

摘要： peptide-steroid conjugates has been addressed. Utilizing |  conjugates of steroids with other biologically relevant | A general approach towards the preparation of |  the Ugi reaction, five peptidomimetic-steroid |  hybrids were achieved in good to excellent yields from

关键词： steroids |  spirostanes |  steroid conjugates |  multicomponent reactions |  Ugi reaction |  PROTEASE-LIKE ACTIVITY |  MULTICOMPONENT REACTIONS |  RECEPTOR LIBRARY |  1 HEMISPHERE |  CHEMISTRY...

Leuschner C |  Enright FM... -  《Breast cancer research and treatment》 - 2003,78(1) - 17～27 - 共11页

摘要： peptide conjugates. Hecate, hecate-betaCG and LHRH |  cells to both lytic peptide conjugates and this | We have prepared conjugates of a membrane |  disrupting lytic peptide (hecate) and a 15-amino acid | ). We have tested the concept that these conjugates

关键词： Peptides |  Gonadorelin |  Malignant neoplasm of breast |  Hormones |  肽类 |  促性腺素释放激素 |  激素类

Sedykh, E.M. |  Zuev, B.K.... -  《Journal of analytical chemistry》 - 2010,65(12) - 1291～1292 - 共2页

摘要： anabolic steroids, β2 agonists, β blockers, substances |  androgen receptor modulators, and peptide hormones |  determination of 36 endogenous steroids and their ratios. An |  enzymatic hydrolysis of sulfo and glucuro-conjugates | Researchers from the FGUP Antidoping Center

Shai Rahimipour |  Nurit Ben-Aroya... -  《Journal of Medicinal Chemistry》 - 2003,46(19) - 3965～3974 - 共10页

摘要： peptide. The conjugates, notably the agonist, were more |  the peptide with PpIX was carried out in a | . Although these conjugates had lower binding affinity to |  phototoxicity of the conjugates toward αT3-1 cells or to human | -incubation with the parent peptide, indicating that

Papadopoulou, Natali... |  Charalampopoulos, Io...... -  《Molecular Cancer》 - 2008,7 - 共13页 - 被引量：42

摘要： steroids or steroid-albumin conjugates did not interfere |  impermeable conjugates of serum albumin covalently linked to |  conjugates further induced FasL expression. A FasL blocking |  peptide abrogated membrane androgen receptors-dependent |  apoptosis. In addition, testosterone-albumin conjugates

关键词： KAPPA-B-ALPHA |  PROTEIN-KINASE |  TESTOSTERONE RECEPTORS |  INTRACELLULAR CALCIUM |  ACTIN REORGANIZATION |  BINDING-SITES |  DEATH |  PHOSPHORYLATION |  CARCINOMA |  UBIQUITINATION