NSTL国家科技图书文献中心

1. Advancing tissue analysis: Integrating mass tags with mass spectrometry imaging and immunohistochemistry NSTL国家科技图书文献中心

Zhang, Dandan | Zhang, Hairong ... - 《Journal of proteomics》 - 2025,316 - 105436～105436 - 共13页

摘要： spectrometry imaging (MSI) are used to detect proteins in | (IHC) and spatial proteomics based on mass | introduction of mass* tags may be adopted to expand the* | , mass* tags can boost the accuracy of qualitative* | review, we aim to discuss the role of different mass

关键词： Mass tag | Mass spectrometry imaging | Immunohistochemistry | Protein | Nanoparticle

2. Spatial lipidomic profiles of atherosclerotic plaques: A mass spectrometry imaging study NSTL国家科技图书文献中心

Ntshangase, Sphamand... | Khan, Shazia ... - 《Talanta》 - 2025,282 - 共9页

摘要：/ionization mass* spectrometry imaging. Histologically | species. Thus, mass spectrometry imaging of spatial* | Lipids contribute to atherosclerotic | cardiovascular disease but their roles are not fully understood | . Spatial lipid composition of atherosclerotic plaques was

关键词： Mass spectrometry imaging | Atherosclerosis | Spatial lipidomics | Histology | Cardiovascular lipid biomarkers

3. Feasibility of IR‐MALDESI Mass Spectrometry Imaging of PFAS NSTL国家科技图书文献中心

Allen Martin | Alena N. Joignant ... - 《Journal of mass spectrometry》 - 2025,60(2) - n/a～n/a - 共10页

摘要：ABSTRACT Perfluoroalkyl and polyfluoroalkyl | substances (PFAS) are a class of emerging contaminants that | have been in use industrially since the 1940s. Their | long‐term and extensive commercial use has led to | their ubiquitous presence in the environment. The

关键词： IR‐MALDESI | LC–MS/MS | mass spectrometry imaging | PFAS | zebrafish

4. Visualization of Efavirenz-Induced Lipid Alterations in the Mouse Brain Using MALDI Mass Spectrometry Imaging NSTL国家科技图书文献中心

Phulara, Nav Raj | Seneviratne, Herana ... - 《Current protocols.》 - 2025,5(2) - e70108～e70108 - 共17页

摘要： spectrometry imaging (MALDI MSI) methods for detecting and | 1: MALDI mass* spectrometry (MALDI MS) profiling* | matrix-assisted laser desorption/ionization mass | lipids. Described here is the use of a chemical imaging | , identification, and tissue imaging. Lipid detection includes

关键词： brain | drug response | efavirenz | lipids | MALDI mass spectrometry imaging

5. Mitigating Nephrotoxicity Risks and Ranking Drug Candidates Using MALDI Mass Spectrometry Imaging: A Case Study NSTL国家科技图书文献中心

Bingming Chen | Lisa LaFranco-Scheuc...... - 《Toxicologic pathology》 - 2025,53(1) - 45～54 - 共10页

摘要： desorption/ionization mass* spectrometry imaging (MALDI-MSI* | Drug-induced nephrotoxicity is a major | challenge in drug discovery and development, accounting | for nearly a quarter of severe adverse effects in | current pharmacotherapy. Antimicrobial use may be

关键词： mass spectrometry imaging | MALDI | nephrotoxicity | drug discovery | lead optimization

6. Mass spectrometry imaging in food safety and authenticity: Overcoming challenges and exploring opportunities NSTL国家科技图书文献中心

Tortorella S. | Bartels B.... - 《Trends in Food Science & Technology》 - 2025,155 - 1～16 - 共16页

摘要： information is accessible by mass* spectrometry imaging (MSI* | © 2024 The AuthorsBackground: The combination | of molecular profiling capabilities and spatial | ), which has gained substantial importance over the last | 20 years in the analytical community. The number of

关键词： Food authentication | Food safety | Mass spectrometry imaging | Spatial distribution

7. Part A: Implementing an Analyte Panel and Sampling Protocol for Quality Control in Mass Spectrometry Imaging NSTL国家科技图书文献中心

Mills, Quinn | Kibbe, Russell R.... - 《Rapid Communications in Mass Spectrometry》 - 2025,39(8) - n/a～n/a - 共8页

摘要： Classification and Evaluation for Mass Spectrometry Imaging | mass spectrometry, the field of mass spectrometry | imaging (MSI) currently lacks any universally accepted | that reflects a typical MSI imaging* experiment, and* | imaging experiments for continuous evaluation of

关键词： IR-MALDESI | mass spectrometry imaging | quality control | stable isotope labeled | system suitability testing | IR‐MALDESI

8. Mass Spectrometry Imaging Unveils the Metabolic Effect of 6PPD-Quinone in Exposed Mice NSTL国家科技图书文献中心

Ke Jia | Jiameng Sun ... - 《Environmental Science & Technology》 - 2025,59(9) - 4282～4291 - 共10页

摘要：-assisted laser desorption/ionization mass spectrometry | imaging (MALDI MSI) was applied to evaluate its effects | N-(1,3-dimethylbutyl)-N'-phenyl-p | -phenylenediamine quinone (6PPD-Q) has gained widespread attention | as an emerging significant environmental

关键词： 6PPD-Q | matrix assisted laser desorption/ionization mass spectrometry | mass spectrometry imaging | metabolic profiling

9. European Society of Toxicologic Pathology—Pathology 2.0 Mass Spectrometry Imaging Special Interest Group: Mass Spectrometry Imaging in Diagnostic and Toxicologic Pathology for Label-Free Detection of Molecules—From Basics to Practical Applications NSTL国家科技图书文献中心

Enrico Vezzali | Michael Becker ... - 《Toxicologic pathology》 - 2025,53(1) - 130～158 - 共29页

摘要：Mass Spectrometry Imaging (MSI) is a powerful | Ionization (DESI), and Secondary Ion Mass Spectrometry | tool to understand molecular pathophysiology and | therapeutic and toxicity mechanisms, as well as for patient | stratification and precision medicine. MSI, a label-free

关键词： mass spectrometry imaging | label-free | multiplex | diagnostic pathology | drug development

10. Mass Spectrometry Imaging Distinguishes Biliary Toxicants on the Basis of Cellular Distribution NSTL国家科技图书文献中心

Junhai Yang | Andrew P. Bowman ... - 《Toxicologic pathology》 - 2025,53(1) - 55～64 - 共10页

摘要：Mass spectrometry imaging (MSI) was used to | investigate and provide insights into observed biliary | pathology found in dogs and rats after administration of | two different compounds. Both compounds were | associated with peribiliary inflammatory infiltrates and

摘要： spectrometry imaging (MSI) are used to detect proteins in | (IHC) and spatial proteomics based on mass | introduction of mass* tags may be adopted to expand the* | , mass* tags can boost the accuracy of qualitative* | review, we aim to discuss the role of different mass

关键词： Mass tag | Mass spectrometry imaging | Immunohistochemistry | Protein | Nanoparticle

摘要：/ionization mass* spectrometry imaging. Histologically | species. Thus, mass spectrometry imaging of spatial* | Lipids contribute to atherosclerotic | cardiovascular disease but their roles are not fully understood | . Spatial lipid composition of atherosclerotic plaques was

关键词： Mass spectrometry imaging | Atherosclerosis | Spatial lipidomics | Histology | Cardiovascular lipid biomarkers

摘要：ABSTRACT Perfluoroalkyl and polyfluoroalkyl | substances (PFAS) are a class of emerging contaminants that | have been in use industrially since the 1940s. Their | long‐term and extensive commercial use has led to | their ubiquitous presence in the environment. The

关键词： IR‐MALDESI | LC–MS/MS | mass spectrometry imaging | PFAS | zebrafish

摘要： spectrometry imaging (MALDI MSI) methods for detecting and | 1: MALDI mass* spectrometry (MALDI MS) profiling* | matrix-assisted laser desorption/ionization mass | lipids. Described here is the use of a chemical imaging | , identification, and tissue imaging. Lipid detection includes

关键词： brain | drug response | efavirenz | lipids | MALDI mass spectrometry imaging

摘要： desorption/ionization mass* spectrometry imaging (MALDI-MSI* | Drug-induced nephrotoxicity is a major | challenge in drug discovery and development, accounting | for nearly a quarter of severe adverse effects in | current pharmacotherapy. Antimicrobial use may be

关键词： mass spectrometry imaging | MALDI | nephrotoxicity | drug discovery | lead optimization

摘要： information is accessible by mass* spectrometry imaging (MSI* | © 2024 The AuthorsBackground: The combination | of molecular profiling capabilities and spatial | ), which has gained substantial importance over the last | 20 years in the analytical community. The number of

关键词： Food authentication | Food safety | Mass spectrometry imaging | Spatial distribution

摘要： Classification and Evaluation for Mass Spectrometry Imaging | mass spectrometry, the field of mass spectrometry | imaging (MSI) currently lacks any universally accepted | that reflects a typical MSI imaging* experiment, and* | imaging experiments for continuous evaluation of

关键词： IR-MALDESI | mass spectrometry imaging | quality control | stable isotope labeled | system suitability testing | IR‐MALDESI

摘要：-assisted laser desorption/ionization mass spectrometry | imaging (MALDI MSI) was applied to evaluate its effects | N-(1,3-dimethylbutyl)-N'-phenyl-p | -phenylenediamine quinone (6PPD-Q) has gained widespread attention | as an emerging significant environmental

关键词： 6PPD-Q | matrix assisted laser desorption/ionization mass spectrometry | mass spectrometry imaging | metabolic profiling

摘要：Mass Spectrometry Imaging (MSI) is a powerful | Ionization (DESI), and Secondary Ion Mass Spectrometry | tool to understand molecular pathophysiology and | therapeutic and toxicity mechanisms, as well as for patient | stratification and precision medicine. MSI, a label-free

关键词： mass spectrometry imaging | label-free | multiplex | diagnostic pathology | drug development

摘要：Mass spectrometry imaging (MSI) was used to | investigate and provide insights into observed biliary | pathology found in dogs and rats after administration of | two different compounds. Both compounds were | associated with peribiliary inflammatory infiltrates and

关键词： mass spectrometry imaging | pharmaceutical | drug development | drug discovery | toxicity | MALDI-MS | drug-induced liver injury

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： spectrometry imaging (MSI) are used to detect proteins in | (IHC) and spatial proteomics based on mass | introduction of mass tags may be adopted to expand the | , mass tags can boost the accuracy of qualitative | review, we aim to discuss the role of different mass

关键词： Mass tag | Mass spectrometry imaging | Immunohistochemistry | Protein | Nanoparticle

摘要：/ionization mass spectrometry imaging. Histologically | species. Thus, mass spectrometry imaging of spatial | Lipids contribute to atherosclerotic | cardiovascular disease but their roles are not fully understood | . Spatial lipid composition of atherosclerotic plaques was

关键词： Mass spectrometry imaging | Atherosclerosis | Spatial lipidomics | Histology | Cardiovascular lipid biomarkers

摘要：ABSTRACT Perfluoroalkyl and polyfluoroalkyl | substances (PFAS) are a class of emerging contaminants that | have been in use industrially since the 1940s. Their | long‐term and extensive commercial use has led to | their ubiquitous presence in the environment. The

关键词： IR‐MALDESI | LC–MS/MS | mass spectrometry imaging | PFAS | zebrafish

摘要： spectrometry imaging (MALDI MSI) methods for detecting and | 1: MALDI mass spectrometry (MALDI MS) profiling | matrix-assisted laser desorption/ionization mass | lipids. Described here is the use of a chemical imaging | , identification, and tissue imaging. Lipid detection includes

关键词： brain | drug response | efavirenz | lipids | MALDI mass spectrometry imaging

摘要： desorption/ionization mass spectrometry imaging (MALDI-MSI | Drug-induced nephrotoxicity is a major | challenge in drug discovery and development, accounting | for nearly a quarter of severe adverse effects in | current pharmacotherapy. Antimicrobial use may be

关键词： mass spectrometry imaging | MALDI | nephrotoxicity | drug discovery | lead optimization

摘要： information is accessible by mass spectrometry imaging (MSI | © 2024 The AuthorsBackground: The combination | of molecular profiling capabilities and spatial | ), which has gained substantial importance over the last | 20 years in the analytical community. The number of

关键词： Food authentication | Food safety | Mass spectrometry imaging | Spatial distribution

摘要： Classification and Evaluation for Mass Spectrometry Imaging | mass spectrometry, the field of mass spectrometry | imaging (MSI) currently lacks any universally accepted | that reflects a typical MSI imaging experiment, and | imaging experiments for continuous evaluation of

关键词： IR-MALDESI | mass spectrometry imaging | quality control | stable isotope labeled | system suitability testing | IR‐MALDESI

摘要：-assisted laser desorption/ionization mass spectrometry | imaging (MALDI MSI) was applied to evaluate its effects | N-(1,3-dimethylbutyl)-N'-phenyl-p | -phenylenediamine quinone (6PPD-Q) has gained widespread attention | as an emerging significant environmental

关键词： 6PPD-Q | matrix assisted laser desorption/ionization mass spectrometry | mass spectrometry imaging | metabolic profiling

摘要：Mass Spectrometry Imaging (MSI) is a powerful | Ionization (DESI), and Secondary Ion Mass Spectrometry | tool to understand molecular pathophysiology and | therapeutic and toxicity mechanisms, as well as for patient | stratification and precision medicine. MSI, a label-free

关键词： mass spectrometry imaging | label-free | multiplex | diagnostic pathology | drug development

摘要：Mass spectrometry imaging (MSI) was used to | investigate and provide insights into observed biliary | pathology found in dogs and rats after administration of | two different compounds. Both compounds were | associated with peribiliary inflammatory infiltrates and

关键词： mass spectrometry imaging | pharmaceutical | drug development | drug discovery | toxicity | MALDI-MS | drug-induced liver injury

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： spectrometry imaging (MSI) are used to detect proteins in | (IHC) and spatial proteomics based on mass | introduction of mass* tags may be adopted to expand the* | , mass* tags can boost the accuracy of qualitative* | review, we aim to discuss the role of different mass

摘要：/ionization mass* spectrometry imaging. Histologically | species. Thus, mass spectrometry imaging of spatial* | Lipids contribute to atherosclerotic | cardiovascular disease but their roles are not fully understood | . Spatial lipid composition of atherosclerotic plaques was

摘要： spectrometry imaging (MALDI MSI) methods for detecting and | 1: MALDI mass* spectrometry (MALDI MS) profiling* | matrix-assisted laser desorption/ionization mass | lipids. Described here is the use of a chemical imaging | , identification, and tissue imaging. Lipid detection includes

摘要： desorption/ionization mass* spectrometry imaging (MALDI-MSI* | Drug-induced nephrotoxicity is a major | challenge in drug discovery and development, accounting | for nearly a quarter of severe adverse effects in | current pharmacotherapy. Antimicrobial use may be

摘要： information is accessible by mass* spectrometry imaging (MSI* | © 2024 The AuthorsBackground: The combination | of molecular profiling capabilities and spatial | ), which has gained substantial importance over the last | 20 years in the analytical community. The number of

摘要： Classification and Evaluation for Mass Spectrometry Imaging | mass spectrometry, the field of mass spectrometry | imaging (MSI) currently lacks any universally accepted | that reflects a typical MSI imaging* experiment, and* | imaging experiments for continuous evaluation of