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1. Monoclonal antibodies against jellyfish collagen NSTL国家科技图书文献中心

Momma, Keiko | Shimizu, Takeyuki ... - 《Journal of biomaterials applications》 - 2025,39(7) - 807～815 - 共9页

摘要： collagen, we generated four monoclonal* antibodies, MCOL1* | antibodies were determined. The antibody-binding kinetics | other antibodies, MCOL2 could recognize the common and | . Therefore, this monoclonal* antibody will be most* | sequences of the variable regions of the monoclonal

关键词： binding specificity | collagen | jellyfish | monoclonal antibody | surface plasmon resonance

2. Targeted Therapies: The Role of Monoclonal Antibodies in Disease Management NSTL国家科技图书文献中心

Salah, Akram N. | Hashem, Amr H.... - 《Journal of biochemical and molecular toxicology》 - 2025,39(2) - e70163～e70163 - 共20页

摘要：Monoclonal antibodies (mAbs) are a key class | of biotherapeutic medicines used to treat a wide | range of diseases, such as cancer, infectious diseases | , autoimmune disorders, cardiovascular diseases, and | hemophilia. They can be engineered for greater

关键词： autoimmune disorders | cancer therapy | infectious diseases | metabolic disorders | monoclonal antibodies (mAbs) | nanoparticle technology

3. Therapeutic Potential of Neutralizing Monoclonal Antibodies (nMAbs) against SARS-CoV-2 Omicron Variant NSTL国家科技图书文献中心

Parua, Pijus | Ghosh, Somnath ... - 《Current pharmaceutical design》 - 2025,31(10) - 753～773 - 共21页

摘要： drugs, specifically monoclonal* antibodies and* | Discussion Neutralizing monoclonal* antibodies (nMAbs* | antibodies and variant combinations. For instance | varies significantly across different monoclonal | . Subsequently, WKS13, mAb-39, 19n01, F61-d2 cocktail, etc

关键词： Antiviral | mutation | neutralizing monoclonal antibodies (nMAbs) | SARS-CoV-2 | spike inhibition | COVID-19

4. Nano-engineered monoclonal antibodies expanding the newer avenues for cancer targeting NSTL国家科技图书文献中心

Janakiraman, Kumar | Jayaraj, Gracesugant...... - 《Macromolecular Research》 - 2025,33(2) - 117～135 - 共19页

摘要：The monoclonal* antibodies (mAbs) selectively* | mAbs.Graphical abstractMonoclonal antibodies* covalently linked* | hinder the signaling involved in tumor growth and/or | stimulate immune responses against tumor cells. Through | the combination of mAbs, it is possible to target

关键词： Antibody | Monoclonal antibodies | Tumor cells | Nanoparticle | Bevacizumab | Cetuximab | Panitumumab

5. Immunochemical Characteristics and Functional Activity of Monoclonal Antibodies Obtained to the Recombinant Form of Pneumolysin NSTL国家科技图书文献中心

Yakovleva, I. V. | Gavrilova, N. F.... - 《Bulletin of experimental biology and medicine》 - 2025,178(3) - 346～350 - 共5页

摘要：Monoclonal antibodies (mAbs) of the IgG1 | same time, polyclonal antibodies* (pAbs(rPly* | were used as capture and detecting antibodies | isotype obtained to the full-length recombinant | pneumolysin (rPly) did not recognize or poorly recognized

关键词： monoclonal antibodies | recombinant pneumolysin | native pneumolysin | inhibition of hemolytic activity | sandwich ELISA

6. Switching between anti-CGRP monoclonal antibodies in migraine prophylaxis NSTL国家科技图书文献中心

Vikelis, Michail | Rikos, Dimitrios ... - 《Expert review of neurotherapeutics》 - 2025,25(3) - 359～374 - 共16页

摘要： monoclonal antibody (anti-CGRP mAb) fails, switching to a | different anti-CGRP mAb* is an option often considered* | therapy with a first anti-CGRP mAb* fails for any reason* | Introduction: When a first anti-CGRP | , despite the fact that this approach is not yet

关键词： Migraine | calcitonin gene-related peptide receptor | monoclonal antibodies | switching | erenumab | fremanezumab | galcanezumab | eptinezumab

7. Lessons from the Use of Monoclonal Antibodies to SARS-CoV-2 Spike Protein During the COVID-19 Pandemic NSTL国家科技图书文献中心

Casadevall, Arturo | Focosi, Daniele - 《Annual Review of Medicine》 - 2025,76 - 1～12 - 共12页

摘要：Monoclonal antibodies (mAbs) targeting the | SARS-CoV-2 Spike protein were deployed during the | COVID-19 pandemic. While all of the clinically | authorized mAbs were eventually defeated by SARS-CoV-2 | variants, they were highly effective in preventing

关键词： monoclonal antibodies | Spike | COVID-19 | SARS-CoV-2

8. Successes and failures: the latest advances in the clinical development of amyloid-β-targeting monoclonal antibodies for treating Alzheimer's disease NSTL国家科技图书文献中心

Panza, Francesco | Dibello, Vittorio ... - 《Expert opinion on biological therapy》 - 2025,25(3) - 275～283 - 共9页

摘要： beta monoclonal* antibodies, has produced discussible* | failure of previous anti-A beta monoclonal antibodies | anti-A beta monoclonal* antibodies in AD and* | and failures of anti-A beta monoclonal antibody | IntroductionThe amyloid cascade hypothesis

关键词： Alzheimer's disease | amyloid-beta | disease-modifying drugs | mild cognitive impairment | monoclonal antibodies | tau protein

9. Fever exerts opposing effects on the binding affinities of two neutralizing monoclonal antibodies against Staphylococcal Enterotoxin B NSTL国家科技图书文献中心

Singh, Puneet K. | Choi, Su-Mi ... - 《Journal of Thermal Biology》 - 2025,129 - 共6页

摘要： with neutralizing monoclonal* antibodies against a key* | antibodies, 6D3 and 14G8. Results: Using molecular dynamics | antibodies used in the therapy against S. aureus, and | complexes between SEB and two therapeutic monoclonal | activity of 6D3 mAb* is markedly reduced. In contrast, the*

关键词： Molecular dynamics | Fever | Neutralizing monoclonal antibodies | S. aureus | Staphylococcal Enterotoxin B | Surface plasmon resonance

10. Generation of Conformation-Specific Monoclonal Antibodies for Integral Membrane Proteins NSTL国家科技图书文献中心

Sheldon, Natalie | Dhandapani, Gunaseka...... - 《Current protocols.》 - 2025,5(5) - e70142～e70142 - 共33页

摘要： effort to developing murine monoclonal* antibodies (mAbs* | Antibodies and their antigen-binding fragments | , detection, and quantification studies. Most antibodies | -specific antibodies, by contrast, bind to 3D epitopes | antibodies recognize 3D shapes of the antigen, they often

关键词： crystallization chaperones | fragment antigen‐binding region | glutamate receptors | proteoliposomes | single‐chain variable fragment | fragment antigen-binding region | single-chain variable fragment

摘要： collagen, we generated four monoclonal antibodies, MCOL1 | antibodies were determined. The antibody-binding kinetics | other antibodies, MCOL2 could recognize the common and | . Therefore, this monoclonal antibody will be most | sequences of the variable regions of the monoclonal

关键词： binding specificity | collagen | jellyfish | monoclonal antibody | surface plasmon resonance

摘要：Monoclonal antibodies (mAbs) are a key class | of biotherapeutic medicines used to treat a wide | range of diseases, such as cancer, infectious diseases | , autoimmune disorders, cardiovascular diseases, and | hemophilia. They can be engineered for greater

关键词： autoimmune disorders | cancer therapy | infectious diseases | metabolic disorders | monoclonal antibodies (mAbs) | nanoparticle technology

摘要： drugs, specifically monoclonal antibodies and | Discussion Neutralizing monoclonal antibodies (nMAbs | antibodies and variant combinations. For instance | varies significantly across different monoclonal | . Subsequently, WKS13, mAb-39, 19n01, F61-d2 cocktail, etc

关键词： Antiviral | mutation | neutralizing monoclonal antibodies (nMAbs) | SARS-CoV-2 | spike inhibition | COVID-19

摘要：The monoclonal antibodies (mAbs) selectively | mAbs.Graphical abstractMonoclonal antibodies covalently linked | hinder the signaling involved in tumor growth and/or | stimulate immune responses against tumor cells. Through | the combination of mAbs, it is possible to target

关键词： Antibody | Monoclonal antibodies | Tumor cells | Nanoparticle | Bevacizumab | Cetuximab | Panitumumab

摘要：Monoclonal antibodies (mAbs) of the IgG1 | same time, polyclonal antibodies (pAbs(rPly | were used as capture and detecting antibodies | isotype obtained to the full-length recombinant | pneumolysin (rPly) did not recognize or poorly recognized

关键词： monoclonal antibodies | recombinant pneumolysin | native pneumolysin | inhibition of hemolytic activity | sandwich ELISA

摘要： monoclonal antibody (anti-CGRP mAb) fails, switching to a | different anti-CGRP mAb is an option often considered | therapy with a first anti-CGRP mAb fails for any reason | Introduction: When a first anti-CGRP | , despite the fact that this approach is not yet

关键词： Migraine | calcitonin gene-related peptide receptor | monoclonal antibodies | switching | erenumab | fremanezumab | galcanezumab | eptinezumab

摘要：Monoclonal antibodies (mAbs) targeting the | SARS-CoV-2 Spike protein were deployed during the | COVID-19 pandemic. While all of the clinically | authorized mAbs were eventually defeated by SARS-CoV-2 | variants, they were highly effective in preventing

关键词： monoclonal antibodies | Spike | COVID-19 | SARS-CoV-2

摘要： beta monoclonal antibodies, has produced discussible | failure of previous anti-A beta monoclonal antibodies | anti-A beta monoclonal antibodies in AD and | and failures of anti-A beta monoclonal antibody | IntroductionThe amyloid cascade hypothesis

关键词： Alzheimer's disease | amyloid-beta | disease-modifying drugs | mild cognitive impairment | monoclonal antibodies | tau protein

摘要： with neutralizing monoclonal antibodies against a key | antibodies, 6D3 and 14G8. Results: Using molecular dynamics | antibodies used in the therapy against S. aureus, and | complexes between SEB and two therapeutic monoclonal | activity of 6D3 mAb is markedly reduced. In contrast, the

关键词： Molecular dynamics | Fever | Neutralizing monoclonal antibodies | S. aureus | Staphylococcal Enterotoxin B | Surface plasmon resonance

摘要： effort to developing murine monoclonal antibodies (mAbs | Antibodies and their antigen-binding fragments | , detection, and quantification studies. Most antibodies | -specific antibodies, by contrast, bind to 3D epitopes | antibodies recognize 3D shapes of the antigen, they often

关键词： crystallization chaperones | fragment antigen‐binding region | glutamate receptors | proteoliposomes | single‐chain variable fragment | fragment antigen-binding region | single-chain variable fragment

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摘要： collagen, we generated four monoclonal* antibodies, MCOL1* | antibodies were determined. The antibody-binding kinetics | other antibodies, MCOL2 could recognize the common and | . Therefore, this monoclonal* antibody will be most* | sequences of the variable regions of the monoclonal

摘要： drugs, specifically monoclonal* antibodies and* | Discussion Neutralizing monoclonal* antibodies (nMAbs* | antibodies and variant combinations. For instance | varies significantly across different monoclonal | . Subsequently, WKS13, mAb-39, 19n01, F61-d2 cocktail, etc

摘要：The monoclonal* antibodies (mAbs) selectively* | mAbs.Graphical abstractMonoclonal antibodies* covalently linked* | hinder the signaling involved in tumor growth and/or | stimulate immune responses against tumor cells. Through | the combination of mAbs, it is possible to target

摘要：Monoclonal antibodies (mAbs) of the IgG1 | same time, polyclonal antibodies* (pAbs(rPly* | were used as capture and detecting antibodies | isotype obtained to the full-length recombinant | pneumolysin (rPly) did not recognize or poorly recognized

摘要： monoclonal antibody (anti-CGRP mAb) fails, switching to a | different anti-CGRP mAb* is an option often considered* | therapy with a first anti-CGRP mAb* fails for any reason* | Introduction: When a first anti-CGRP | , despite the fact that this approach is not yet

摘要： beta monoclonal* antibodies, has produced discussible* | failure of previous anti-A beta monoclonal antibodies | anti-A beta monoclonal* antibodies in AD and* | and failures of anti-A beta monoclonal antibody | IntroductionThe amyloid cascade hypothesis

摘要： effort to developing murine monoclonal* antibodies (mAbs* | Antibodies and their antigen-binding fragments | , detection, and quantification studies. Most antibodies | -specific antibodies, by contrast, bind to 3D epitopes | antibodies recognize 3D shapes of the antigen, they often