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1. Microglia heterogeneity during neuroinflammation and neurodegeneration in the mouse retina NSTL国家科技图书文献中心

Bilin,Rao |  Xiaoqing,Liu... -  《Brain structure & function》 - 2025,230(1) - Article: 19~Article: 19 - 共20页

摘要: central nervous system including retina. To accomplish |  neurodegeneration model to explore these questions in the mouse |  retina. Immunofluorescence and EM were used to detect |  mouse retinas in the neuroinflammatory model and the | Abstract Microglia play important roles in
关键词: Microglia |  Heterogeneity |  Dynamics |  Dark microglia |  Light microscopy |  Electron microscopy

2. Evaluating the effects of three anesthetic regimens on retinal structure and function in the living mouse eye using a customized bimodal OCT/ORG system NSTL国家科技图书文献中心

Ma, Yanhong |  Dong, Rongyao... -  《Journal of Physics,D.Applied Physics》 - 2025,58(3) - 共13页

摘要: (ORG) functional assessment of mouse retina to | -modality imaging of mouse retinal structure and function | Optical coherence tomography (OCT) is a non | -invasive imaging technique that generates cross-sectional |  images of biological tissues at millimeter-level
关键词: optical coherence tomography |  optoretinography |  mouse retina |  anesthesia |  in vivo imaging |  functional imaging

3. A New Targeted Transgenic Mouse Line for the Study of Protocadherin γC4 NSTL国家科技图书文献中心

Mcleod, Cathy M. |  Hanes, Camille M.... -  《Genesis :》 - 2025,63(1) - e70010~e70010 - 共7页

摘要: survival in mice. Here we describe a new mouse line (C4 | The gamma-protocadherins (gamma-Pcdhs | ) comprise 22 homophilic cell adhesion molecule isoforms | , expressed from the Pcdhg gene cluster via promoter choice |  mechanisms that serve many crucial functions during neural
关键词: clustered protocadherin |  mouse |  retina |  spinal cord

4. The Deubiquitinase USP2 Modulates Photic Entrainment of the Circadian Clock at the Level of the Suprachiasmatic Nucleus NSTL国家科技图书文献中心

Srikanta, Shashank B... |  Brown, Thomas W.... -  《Journal of neurochemistry.》 - 2025,169(2) - e70018~e70018 - 共18页

摘要:, and in the retina. This raised the question of where |  it is not within the retina, as retinas of Usp2 KO |  ganglion cells. Moreover, KO of Usp2 within the retina | Ubiquitin-specific peptidase 2 (USP2) is a |  deubiquitinase (DUB) with a diversity of functions in
关键词: circadian clock light |  knock-out mouse |  retina |  suprachiasmatic nucleus |  USP2 |  knock‐out mouse

5. Effects of miR-21/NLRP3 on Blue Light-Induced Retinal Neurodegeneration in Mice NSTL国家科技图书文献中心

Zhang, Yi |  Xu, Xingzhao -  《Current Eye Research》 - 2025,50(3) - 295~303 - 共9页

摘要: inflammasome in the mouse retina. | -induced neurodegeneration in the mouse retina.MethodsA |  mouse model of retinal light damage was established |  locate microglia and NLRP3 expression in the mouse |  retina. The expression of miR-21, NLRP3, and downstream
关键词: Retinal photodamage |  blue light exposure |  age-related macular degeneration |  miR-21/NLRP3

6. Mammalian Retinal Bipolar Cells: Morphological Identification and Systematic Classification in Rabbit Retina With a Comparative Perspective NSTL国家科技图书文献中心

Famiglietti, Edward ... -  《The Journal of Comparative Neurology》 - 2025,533(2) - e70015~e70015 - 共65页

摘要:). Twenty years later, 10 were identified in mouse, rat |  indicate that there are 15 types of bipolar cell in mouse |  retina (Shekhar et al., 2016). The present detailed |  cell in rabbit retina. These have been carefully | . Homologies with bipolar cells of mouse and monkey are
关键词: bipolar cells |  photoreceptors |  ganglion cells |  dendritic branching |  axon terminal field size |  IPL stratification |  fiducial starburst amacrine cells |  immunocytochemical staining |  anti-calbindin-D (28k) (Sigma-Aldrich Cat# C9848 | RRID:AB_476894) |  anti‐calbindin‐D (28k) (Sigma–Aldrich Cat# C9848...

7. Vasoinhibin is Generated by the Renin-angiotensin System NSTL国家科技图书文献中心

Nunez, Francisco Fre... |  Siqueiros-Marquez, L...... -  《Endocrinology》 - 2025,166(3) - bqaf023~bqaf023 - 共9页

摘要: cleaves PRL to vasoinhibin in the newborn mouse retina |  retina of neonate mice as revealed by the CTSD |  renin. Because renin is expressed in the retina and |  and in the circulation. Newborn mouse retinal |  rat and mouse PRLs and at Leu126-Leu127 in human
关键词: vasoinhibin |  prolactin |  renin |  renin-angiotensin system |  retina |  comparative endocrinology

8. A Dual-Branch Multidomain Feature Fusion Network for Axial Super-Resolution in Optical Coherence Tomography NSTL国家科技图书文献中心

Quanqing Xu |  Xiang He... -  《IEEE signal processing letters》 - 2025,32 - 461~465 - 共5页

摘要: achieved the best performance in the tests of mouse |  retina and human retina datasets, outperforming the | High-resolution retinal optical coherence |  tomography(OCT) images are crucial for the diagnosis of |  numerous retinal diseases, but images acquired by narrow
关键词: Feature extraction |  Convolution |  Image reconstruction |  Retina |  Frequency-domain analysis |  Superresolution |  Data mining |  Signal resolution |  Spatial resolution |  Bandwidth

9. PKG‐Mediated Phosphorylation of TOP2A Activates HDAC to Drive Photoreceptor Cell Death in rd1 Mouse Inherited Retinal Degeneration NSTL国家科技图书文献中心

Yujie Dong |  Wandong Zuo... -  《Journal of neurochemistry.》 - 2025,169(5) - e70077~e70077 - 共16页

摘要: observed in the rd1 mouse retina compared with wild‐type |  histone deacetylase (HDAC) in the rd1 mouse model for | ABSTRACT Inherited retinal degeneration (IRD | ) is a debilitating condition characterized by |  progressive loss of photoreceptor cells. However, the
关键词: cGMP/PKG‐signaling pathway |  epigenetic modulation |  inherited retinal degeneration |  neurodegenerative mechanisms |  photoreceptor death

10. Mouse NR2E3 R296Q Mutation Disrupts Photoreceptor Developmental Paradigm and Leads to Early-Onset Progressive Retinal Degeneration by Suppressing RXRG Signaling NSTL国家科技图书文献中心

Jin, Jiacheng |  Wang, Shuai... -  《The FASEB Journal》 - 2025,39(9) - e70524~e70524 - 共13页

摘要:. In this study, we generated a mouse strain carrying |  excessively produced at the dorsal retina, whereas green |  and outer segment fragmentation. The dorsal retina |  expressions. In summary, we developed a novel mouse model | The NR2E3R311Q mutation can lead to retinitis
关键词: CRISPR‐Cas9 |  ESCS |  NR2E3R296Q mutation |  photoreceptor development |  retinal degeneration |  RXRG signaling |  CRISPR-Cas9
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