NSTL国家科技图书文献中心

1. Microglia heterogeneity during neuroinflammation and neurodegeneration in the mouse retina NSTL国家科技图书文献中心

Bilin,Rao | Xiaoqing,Liu ... - 《Brain structure & function》 - 2025,230(1) - Article: 19～Article: 19 - 共20页

摘要： central nervous system including retina. To accomplish | neurodegeneration model to explore these questions in the mouse | retina. Immunofluorescence and EM were used to detect | mouse retinas in the neuroinflammatory model and the | Abstract Microglia play important roles in

关键词： Microglia | Heterogeneity | Dynamics | Dark microglia | Light microscopy | Electron microscopy

2. Evaluating the effects of three anesthetic regimens on retinal structure and function in the living mouse eye using a customized bimodal OCT/ORG system NSTL国家科技图书文献中心

Ma, Yanhong | Dong, Rongyao ... - 《Journal of Physics,D.Applied Physics》 - 2025,58(3) - 共13页

摘要： (ORG) functional assessment of mouse* retina to* | -modality imaging of mouse* retinal structure and function* | Optical coherence tomography (OCT) is a non | -invasive imaging technique that generates cross-sectional | images of biological tissues at millimeter-level

关键词： optical coherence tomography | optoretinography | mouse retina | anesthesia | in vivo imaging | functional imaging

3. A New Targeted Transgenic Mouse Line for the Study of Protocadherin γC4 NSTL国家科技图书文献中心

Mcleod, Cathy M. | Hanes, Camille M.... - 《Genesis :》 - 2025,63(1) - e70010～e70010 - 共7页

摘要： survival in mice. Here we describe a new mouse* line (C4* | The gamma-protocadherins (gamma-Pcdhs | ) comprise 22 homophilic cell adhesion molecule isoforms | , expressed from the Pcdhg gene cluster via promoter choice | mechanisms that serve many crucial functions during neural

关键词： clustered protocadherin | mouse | retina | spinal cord

4. The Deubiquitinase USP2 Modulates Photic Entrainment of the Circadian Clock at the Level of the Suprachiasmatic Nucleus NSTL国家科技图书文献中心

Srikanta, Shashank B... | Brown, Thomas W.... - 《Journal of neurochemistry.》 - 2025,169(2) - e70018～e70018 - 共18页

摘要：, and in the retina. This raised the question of where | it is not within the retina, as retinas of Usp2 KO | ganglion cells. Moreover, KO of Usp2 within the retina | Ubiquitin-specific peptidase 2 (USP2) is a | deubiquitinase (DUB) with a diversity of functions in

关键词： circadian clock light | knock-out mouse | retina | suprachiasmatic nucleus | USP2 | knock‐out mouse

5. Effects of miR-21/NLRP3 on Blue Light-Induced Retinal Neurodegeneration in Mice NSTL国家科技图书文献中心

Zhang, Yi | Xu, Xingzhao - 《Current Eye Research》 - 2025,50(3) - 295～303 - 共9页

摘要： inflammasome in the mouse* retina.* | -induced neurodegeneration in the mouse* retina.MethodsA* | mouse model of retinal light damage was established | locate microglia and NLRP3 expression in the mouse | retina. The expression of miR-21, NLRP3, and downstream

关键词： Retinal photodamage | blue light exposure | age-related macular degeneration | miR-21/NLRP3

6. Mammalian Retinal Bipolar Cells: Morphological Identification and Systematic Classification in Rabbit Retina With a Comparative Perspective NSTL国家科技图书文献中心

Famiglietti, Edward ... - 《The Journal of Comparative Neurology》 - 2025,533(2) - e70015～e70015 - 共65页

摘要：). Twenty years later, 10 were identified in mouse, rat | indicate that there are 15 types of bipolar cell in mouse | retina (Shekhar et al., 2016). The present detailed | cell in rabbit retina. These have been carefully | . Homologies with bipolar cells of mouse* and monkey are*

关键词： bipolar cells | photoreceptors | ganglion cells | dendritic branching | axon terminal field size | IPL stratification | fiducial starburst amacrine cells | immunocytochemical staining | anti-calbindin-D (28k) (Sigma-Aldrich Cat# C9848 | RRID:AB_476894) | anti‐calbindin‐D (28k) (Sigma–Aldrich Cat# C9848...

7. Vasoinhibin is Generated by the Renin-angiotensin System NSTL国家科技图书文献中心

Nunez, Francisco Fre... | Siqueiros-Marquez, L...... - 《Endocrinology》 - 2025,166(3) - bqaf023～bqaf023 - 共9页

摘要： cleaves PRL to vasoinhibin in the newborn mouse retina | retina of neonate mice as revealed by the CTSD | renin. Because renin is expressed in the retina* and* | and in the circulation. Newborn mouse* retinal* | rat and mouse* PRLs and at Leu126-Leu127 in human*

关键词： vasoinhibin | prolactin | renin | renin-angiotensin system | retina | comparative endocrinology

8. A Dual-Branch Multidomain Feature Fusion Network for Axial Super-Resolution in Optical Coherence Tomography NSTL国家科技图书文献中心

Quanqing Xu | Xiang He ... - 《IEEE signal processing letters》 - 2025,32 - 461～465 - 共5页

摘要： achieved the best performance in the tests of mouse | retina and human retina datasets, outperforming the | High-resolution retinal optical coherence | tomography(OCT) images are crucial for the diagnosis of | numerous retinal diseases, but images acquired by narrow

关键词： Feature extraction | Convolution | Image reconstruction | Retina | Frequency-domain analysis | Superresolution | Data mining | Signal resolution | Spatial resolution | Bandwidth

9. PKG‐Mediated Phosphorylation of TOP2A Activates HDAC to Drive Photoreceptor Cell Death in rd1 Mouse Inherited Retinal Degeneration NSTL国家科技图书文献中心

Yujie Dong | Wandong Zuo ... - 《Journal of neurochemistry.》 - 2025,169(5) - e70077～e70077 - 共16页

摘要： observed in the rd1 mouse* retina compared with wild‐type* | histone deacetylase (HDAC) in the rd1 mouse* model for* | ABSTRACT Inherited retinal degeneration (IRD | ) is a debilitating condition characterized by | progressive loss of photoreceptor cells. However, the

关键词： cGMP/PKG‐signaling pathway | epigenetic modulation | inherited retinal degeneration | neurodegenerative mechanisms | photoreceptor death

10. Mouse NR2E3 R296Q Mutation Disrupts Photoreceptor Developmental Paradigm and Leads to Early-Onset Progressive Retinal Degeneration by Suppressing RXRG Signaling NSTL国家科技图书文献中心

Jin, Jiacheng | Wang, Shuai ... - 《The FASEB Journal》 - 2025,39(9) - e70524～e70524 - 共13页

摘要：. In this study, we generated a mouse* strain carrying* | excessively produced at the dorsal retina, whereas green | and outer segment fragmentation. The dorsal retina | expressions. In summary, we developed a novel mouse* model* | The NR2E3R311Q mutation can lead to retinitis

摘要： central nervous system including retina. To accomplish | neurodegeneration model to explore these questions in the mouse | retina. Immunofluorescence and EM were used to detect | mouse retinas in the neuroinflammatory model and the | Abstract Microglia play important roles in

关键词： Microglia | Heterogeneity | Dynamics | Dark microglia | Light microscopy | Electron microscopy

摘要： (ORG) functional assessment of mouse* retina to* | -modality imaging of mouse* retinal structure and function* | Optical coherence tomography (OCT) is a non | -invasive imaging technique that generates cross-sectional | images of biological tissues at millimeter-level

关键词： optical coherence tomography | optoretinography | mouse retina | anesthesia | in vivo imaging | functional imaging

摘要： survival in mice. Here we describe a new mouse* line (C4* | The gamma-protocadherins (gamma-Pcdhs | ) comprise 22 homophilic cell adhesion molecule isoforms | , expressed from the Pcdhg gene cluster via promoter choice | mechanisms that serve many crucial functions during neural

关键词： clustered protocadherin | mouse | retina | spinal cord

摘要：, and in the retina. This raised the question of where | it is not within the retina, as retinas of Usp2 KO | ganglion cells. Moreover, KO of Usp2 within the retina | Ubiquitin-specific peptidase 2 (USP2) is a | deubiquitinase (DUB) with a diversity of functions in

关键词： circadian clock light | knock-out mouse | retina | suprachiasmatic nucleus | USP2 | knock‐out mouse

摘要： inflammasome in the mouse* retina.* | -induced neurodegeneration in the mouse* retina.MethodsA* | mouse model of retinal light damage was established | locate microglia and NLRP3 expression in the mouse | retina. The expression of miR-21, NLRP3, and downstream

关键词： Retinal photodamage | blue light exposure | age-related macular degeneration | miR-21/NLRP3

摘要：). Twenty years later, 10 were identified in mouse, rat | indicate that there are 15 types of bipolar cell in mouse | retina (Shekhar et al., 2016). The present detailed | cell in rabbit retina. These have been carefully | . Homologies with bipolar cells of mouse* and monkey are*

摘要： cleaves PRL to vasoinhibin in the newborn mouse retina | retina of neonate mice as revealed by the CTSD | renin. Because renin is expressed in the retina* and* | and in the circulation. Newborn mouse* retinal* | rat and mouse* PRLs and at Leu126-Leu127 in human*

关键词： vasoinhibin | prolactin | renin | renin-angiotensin system | retina | comparative endocrinology

摘要： achieved the best performance in the tests of mouse | retina and human retina datasets, outperforming the | High-resolution retinal optical coherence | tomography(OCT) images are crucial for the diagnosis of | numerous retinal diseases, but images acquired by narrow

关键词： Feature extraction | Convolution | Image reconstruction | Retina | Frequency-domain analysis | Superresolution | Data mining | Signal resolution | Spatial resolution | Bandwidth

摘要： observed in the rd1 mouse* retina compared with wild‐type* | histone deacetylase (HDAC) in the rd1 mouse* model for* | ABSTRACT Inherited retinal degeneration (IRD | ) is a debilitating condition characterized by | progressive loss of photoreceptor cells. However, the

关键词： cGMP/PKG‐signaling pathway | epigenetic modulation | inherited retinal degeneration | neurodegenerative mechanisms | photoreceptor death

摘要：. In this study, we generated a mouse* strain carrying* | excessively produced at the dorsal retina, whereas green | and outer segment fragmentation. The dorsal retina | expressions. In summary, we developed a novel mouse* model* | The NR2E3R311Q mutation can lead to retinitis

关键词： CRISPR‐Cas9 | ESCS | NR2E3R296Q mutation | photoreceptor development | retinal degeneration | RXRG signaling | CRISPR-Cas9

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： central nervous system including retina. To accomplish | neurodegeneration model to explore these questions in the mouse | retina. Immunofluorescence and EM were used to detect | mouse retinas in the neuroinflammatory model and the | Abstract Microglia play important roles in

关键词： Microglia | Heterogeneity | Dynamics | Dark microglia | Light microscopy | Electron microscopy

摘要： (ORG) functional assessment of mouse retina to | -modality imaging of mouse retinal structure and function | Optical coherence tomography (OCT) is a non | -invasive imaging technique that generates cross-sectional | images of biological tissues at millimeter-level

关键词： optical coherence tomography | optoretinography | mouse retina | anesthesia | in vivo imaging | functional imaging

摘要： survival in mice. Here we describe a new mouse line (C4 | The gamma-protocadherins (gamma-Pcdhs | ) comprise 22 homophilic cell adhesion molecule isoforms | , expressed from the Pcdhg gene cluster via promoter choice | mechanisms that serve many crucial functions during neural

关键词： clustered protocadherin | mouse | retina | spinal cord

摘要：, and in the retina. This raised the question of where | it is not within the retina, as retinas of Usp2 KO | ganglion cells. Moreover, KO of Usp2 within the retina | Ubiquitin-specific peptidase 2 (USP2) is a | deubiquitinase (DUB) with a diversity of functions in

关键词： circadian clock light | knock-out mouse | retina | suprachiasmatic nucleus | USP2 | knock‐out mouse

摘要： inflammasome in the mouse retina. | -induced neurodegeneration in the mouse retina.MethodsA | mouse model of retinal light damage was established | locate microglia and NLRP3 expression in the mouse | retina. The expression of miR-21, NLRP3, and downstream

关键词： Retinal photodamage | blue light exposure | age-related macular degeneration | miR-21/NLRP3

摘要：). Twenty years later, 10 were identified in mouse, rat | indicate that there are 15 types of bipolar cell in mouse | retina (Shekhar et al., 2016). The present detailed | cell in rabbit retina. These have been carefully | . Homologies with bipolar cells of mouse and monkey are

摘要： cleaves PRL to vasoinhibin in the newborn mouse retina | retina of neonate mice as revealed by the CTSD | renin. Because renin is expressed in the retina and | and in the circulation. Newborn mouse retinal | rat and mouse PRLs and at Leu126-Leu127 in human

关键词： vasoinhibin | prolactin | renin | renin-angiotensin system | retina | comparative endocrinology

摘要： achieved the best performance in the tests of mouse | retina and human retina datasets, outperforming the | High-resolution retinal optical coherence | tomography(OCT) images are crucial for the diagnosis of | numerous retinal diseases, but images acquired by narrow

关键词： Feature extraction | Convolution | Image reconstruction | Retina | Frequency-domain analysis | Superresolution | Data mining | Signal resolution | Spatial resolution | Bandwidth

摘要： observed in the rd1 mouse retina compared with wild‐type | histone deacetylase (HDAC) in the rd1 mouse model for | ABSTRACT Inherited retinal degeneration (IRD | ) is a debilitating condition characterized by | progressive loss of photoreceptor cells. However, the

关键词： cGMP/PKG‐signaling pathway | epigenetic modulation | inherited retinal degeneration | neurodegenerative mechanisms | photoreceptor death

摘要：. In this study, we generated a mouse strain carrying | excessively produced at the dorsal retina, whereas green | and outer segment fragmentation. The dorsal retina | expressions. In summary, we developed a novel mouse model | The NR2E3R311Q mutation can lead to retinitis

关键词： CRISPR‐Cas9 | ESCS | NR2E3R296Q mutation | photoreceptor development | retinal degeneration | RXRG signaling | CRISPR-Cas9

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： (ORG) functional assessment of mouse* retina to* | -modality imaging of mouse* retinal structure and function* | Optical coherence tomography (OCT) is a non | -invasive imaging technique that generates cross-sectional | images of biological tissues at millimeter-level

摘要： survival in mice. Here we describe a new mouse* line (C4* | The gamma-protocadherins (gamma-Pcdhs | ) comprise 22 homophilic cell adhesion molecule isoforms | , expressed from the Pcdhg gene cluster via promoter choice | mechanisms that serve many crucial functions during neural

摘要： inflammasome in the mouse* retina.* | -induced neurodegeneration in the mouse* retina.MethodsA* | mouse model of retinal light damage was established | locate microglia and NLRP3 expression in the mouse | retina. The expression of miR-21, NLRP3, and downstream

摘要：). Twenty years later, 10 were identified in mouse, rat | indicate that there are 15 types of bipolar cell in mouse | retina (Shekhar et al., 2016). The present detailed | cell in rabbit retina. These have been carefully | . Homologies with bipolar cells of mouse* and monkey are*

摘要： cleaves PRL to vasoinhibin in the newborn mouse retina | retina of neonate mice as revealed by the CTSD | renin. Because renin is expressed in the retina* and* | and in the circulation. Newborn mouse* retinal* | rat and mouse* PRLs and at Leu126-Leu127 in human*

摘要： observed in the rd1 mouse* retina compared with wild‐type* | histone deacetylase (HDAC) in the rd1 mouse* model for* | ABSTRACT Inherited retinal degeneration (IRD | ) is a debilitating condition characterized by | progressive loss of photoreceptor cells. However, the

摘要：. In this study, we generated a mouse* strain carrying* | excessively produced at the dorsal retina, whereas green | and outer segment fragmentation. The dorsal retina | expressions. In summary, we developed a novel mouse* model* | The NR2E3R311Q mutation can lead to retinitis