NSTL国家科技图书文献中心

1. Analytical Quality by Design-Based Approach for the Assay Method Development of Nusinersen Using Liquid Chromatography-High-Resolution Mass Spectrometry NSTL国家科技图书文献中心

Bhalekar, Vijay S. | Shah, Ravi P. - 《Separation Science Plus》 - 2025,8(1) - 共12页 - 被引量：1

摘要： resolution mass spectrometry (HRMS) approach for accurate | achieved through high* resolution MS. The extracted ion* | proposed a hyphenated liquid chromatography (LC)-high | gas flow, and mass* accuracy. The AQbD-based quick LC* | The quality assessment of oligonucleotide

关键词： analytical quality by design | assay method development | liquid chromatography-high resolution mass spectrometry | Nusinersen | oligonucleotides | liquid chromatography–high resolution mass spectrometry

2. High-resolution mass spectrometry-based suspect and nontarget screening of natural toxins in foodstuffs and risk assessment of dietary exposure NSTL国家科技图书文献中心

Zhang Y. | Chen T.... - 《Environmental Pollution》 - 2025,365(Jan.) - 1.1～1.9 - 共9页

摘要： chromatography-high* resolution mass spectrometry (UHPLC-HRMS* | mass spectrometry data were employed to enhance the | © 2024 Elsevier LtdDaily dietary intake | inevitably exposes individuals to various natural toxins | , which may pose potential health threats. Focusing only

关键词： Dietary exposure | Foodstuffs | High-resolution mass spectrometry | Natural toxins | Suspect and nontarget screening

3. Rapid Determination of Isotopic Purity of Stable Isotope (D, 15 N, or 13 C)-Labeled Organic Compounds by Electrospray Ionization-High-Resolution Mass Spectrometry NSTL国家科技图书文献中心

Liang, Chenlong | Ling, Lin ... - 《Rapid Communications in Mass Spectrometry》 - 2025,39(12) - n/a～n/a - 共12页

摘要：. Herein, the electrospray ionization-high-resolution | mass spectrometry (ESI-HRMS) was applied to determine | maximum resolution* setting was insufficient to* | accurate mass* and excluding the isobar interference.* | Rationale: Stable isotope-labeled organic

关键词： electrospray ionization-high resolution mass spectrometry | isotopic purity | representative isotopolog ion | stable isotope-labeled organic compounds | electrospray ionization‐high resolution mass spectrometry | stable isotope‐labeled organic compounds

4. Non-targeted screening of illegal added hypoglycemic drugs and their derivatives in functional foods using characteristic fragment ions scanning based on liquid chromatography-high-resolution mass spectrometry NSTL国家科技图书文献中心

Liu, Yajie | Feng, Feng ... - 《Journal of chromatography,B.Analytical technologies in the biomedical and life sciences》 - 2025,1251 - 共9页

摘要：-resolution* mass *spectrometry. Nine characteristic fragment | mass spectrum database based on ultrahigh-performance | liquid chromatography-quadrupole/orbitrap high | ions were identified by analyzing the mass | mass database. The detection limits of hypoglycemic

关键词： Non-targeted screening | Illegal additive | Characteristic fragment ions | High resolution mass spectrometry | Food safety

5. Characterization of Trivalently Crosslinked C-Terminal Telopeptide of Type I Collagen (CTX) Species in Human Plasma and Serum Using High-Resolution Mass Spectrometry NSTL国家科技图书文献中心

Demeuse, Justine | Determe, William ... - 《Proteomics》 - 2025,25(4) - n/a～n/a - 共12页

摘要：With an aging population, the increased | interest in the monitoring of skeletal diseases such as | osteoporosis led to significant progress in the discovery and | measurement of bone turnover biomarkers since the 2000s | . Multiple markers derived from type I collagen, such as

关键词： affinity chromatography | CTX | high-resolution mass spectrometry | preparative liquid chromatography | proteomics | type I collagen | high‐resolution mass spectrometry

6. Evidence for high-risk pollutants and emerging microbial contaminants at two major bathing ghats of the river Ganga using high-resolution mass spectrometry and metagenomics NSTL国家科技图书文献中心

Singh, Durgesh Narai... | Pandey, Parul ... - 《Gene》 - 2025,933 - 148991～148991 - 共12页

摘要： water samples using High-resolution mass spectrometry | An efficient wastewater treatment plant is | imperative to limit the entry of emerging pollutants (EPs | ) and emerging microbial contaminants (EMCs) in the | river ecosystem. The detection of emerging EPs in

关键词： River Ganga | Municipal and hospital wastewater | Emerging pollutants | Antimicrobial resistance | High-resolution mass spectrometry | Uncultivable AMR pathogens

7. New approaches towards fish authentication: Pollock and hake differentiation by liquid chromatography high resolution mass spectrometry NSTL国家科技图书文献中心

Luciuk, Anna | Paszkowska, Ewa ... - 《Food Control》 - 2025,171 - 共11页

摘要： method using liquid chromatography-high-resolution mass | quadrupole mass* spectrometry may be developed, which will* | spectrometry for authenticating fish products. Our research | differentiating hake and pollock, two widely consumed high-value | Food adulteration is an important and common

关键词： Fish | Food authentication | Fish authenticity testing | Food fraud detection | Liquid chromatography-mass spectrometry | Peptide biomarker

8. Proteogenomic analysis of Cyprinid herpesvirus 2 using high-resolution mass spectrometry NSTL国家科技图书文献中心

Xu, Chen | Yu, Fangxing ... - 《Journal of Virology》 - 2025,99(5) - e0196024～e0196024 - 共14页

摘要： study, we used high-resolution mass spectrometry | Cyprinid herpesvirus 2 (CyHV-2) is the main | pathogen responsible for the development of herpesviral | hematopoietic necrosis disease (HVHND) in crucian carp | (Carassius auratus). The CyHV-2 genome encodes

关键词： Cyprinid herpesvirus 2 | proteogenomics | gene discovery | mass spectrometry

9. Non-targeted detection of cathinones by high-resolution mass spectrometry based on their fragmentation pattern prediction. Application to pyrrolidine analogues in a hair case of PV8 NSTL国家科技图书文献中心

Matey, Jose Manuel | Menendez-Quintanal, ...... - 《Forensic Chemistry》 - 2025,42 - 共15页

摘要： resolution mass spectrometry, is comprehensively evaluated | methodology based on diagnostic fragment criteria using high | Cathinones (i.e., beta-keto phenyl ethyl | amines) are one of the most numerous and widespread | categories among new psychoactive substances. A selective

关键词： New psychoactive substances | NPS | Synthetic drugs | Cathinones | Bath salts | High-resolution mass spectrometry | HRMS | Orbitrap | PV8 | Alpha-pep...

10. Systematic Analysis of the Chemical Components of Gentiana urnula Harry Sm Using SIRIUS and Liquid Chromatography High-Resolution Mass Spectrometry NSTL国家科技图书文献中心

Yan, Zhihong | Ning, Jing ... - 《Rapid Communications in Mass Spectrometry》 - 2025,39(9) - n/a～n/a - 共7页

摘要： high-resolution mass spectrometry (LC-HRMS) to | Sm.ResultsA total of 213 compounds were identified with high | RationaleGentiana urnula Harry Sm is a | frequently utilized traditional Chinese medicine (TCM) with | applications in the treatment of a range of ailments

摘要： resolution mass spectrometry (HRMS) approach for accurate | achieved through high* resolution MS. The extracted ion* | proposed a hyphenated liquid chromatography (LC)-high | gas flow, and mass* accuracy. The AQbD-based quick LC* | The quality assessment of oligonucleotide

关键词： analytical quality by design | assay method development | liquid chromatography-high resolution mass spectrometry | Nusinersen | oligonucleotides | liquid chromatography–high resolution mass spectrometry

摘要： chromatography-high* resolution mass spectrometry (UHPLC-HRMS* | mass spectrometry data were employed to enhance the | © 2024 Elsevier LtdDaily dietary intake | inevitably exposes individuals to various natural toxins | , which may pose potential health threats. Focusing only

关键词： Dietary exposure | Foodstuffs | High-resolution mass spectrometry | Natural toxins | Suspect and nontarget screening

摘要：. Herein, the electrospray ionization-high-resolution | mass spectrometry (ESI-HRMS) was applied to determine | maximum resolution* setting was insufficient to* | accurate mass* and excluding the isobar interference.* | Rationale: Stable isotope-labeled organic

关键词： electrospray ionization-high resolution mass spectrometry | isotopic purity | representative isotopolog ion | stable isotope-labeled organic compounds | electrospray ionization‐high resolution mass spectrometry | stable isotope‐labeled organic compounds

摘要：-resolution* mass *spectrometry. Nine characteristic fragment | mass spectrum database based on ultrahigh-performance | liquid chromatography-quadrupole/orbitrap high | ions were identified by analyzing the mass | mass database. The detection limits of hypoglycemic

关键词： Non-targeted screening | Illegal additive | Characteristic fragment ions | High resolution mass spectrometry | Food safety

摘要：With an aging population, the increased | interest in the monitoring of skeletal diseases such as | osteoporosis led to significant progress in the discovery and | measurement of bone turnover biomarkers since the 2000s | . Multiple markers derived from type I collagen, such as

关键词： affinity chromatography | CTX | high-resolution mass spectrometry | preparative liquid chromatography | proteomics | type I collagen | high‐resolution mass spectrometry

摘要： water samples using High-resolution mass spectrometry | An efficient wastewater treatment plant is | imperative to limit the entry of emerging pollutants (EPs | ) and emerging microbial contaminants (EMCs) in the | river ecosystem. The detection of emerging EPs in

关键词： River Ganga | Municipal and hospital wastewater | Emerging pollutants | Antimicrobial resistance | High-resolution mass spectrometry | Uncultivable AMR pathogens

关键词： Fish | Food authentication | Fish authenticity testing | Food fraud detection | Liquid chromatography-mass spectrometry | Peptide biomarker

摘要： study, we used high-resolution mass spectrometry | Cyprinid herpesvirus 2 (CyHV-2) is the main | pathogen responsible for the development of herpesviral | hematopoietic necrosis disease (HVHND) in crucian carp | (Carassius auratus). The CyHV-2 genome encodes

关键词： Cyprinid herpesvirus 2 | proteogenomics | gene discovery | mass spectrometry

摘要： resolution mass spectrometry, is comprehensively evaluated | methodology based on diagnostic fragment criteria using high | Cathinones (i.e., beta-keto phenyl ethyl | amines) are one of the most numerous and widespread | categories among new psychoactive substances. A selective

关键词： New psychoactive substances | NPS | Synthetic drugs | Cathinones | Bath salts | High-resolution mass spectrometry | HRMS | Orbitrap | PV8 | Alpha-pep...

摘要： high-resolution mass spectrometry (LC-HRMS) to | Sm.ResultsA total of 213 compounds were identified with high | RationaleGentiana urnula Harry Sm is a | frequently utilized traditional Chinese medicine (TCM) with | applications in the treatment of a range of ailments

关键词： compounds classification | compounds identification | Gentiana urnula Harry Sm | LC-HRMS | SIRIUS | LC‐HRMS

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： resolution mass spectrometry (HRMS) approach for accurate | achieved through high resolution MS. The extracted ion | proposed a hyphenated liquid chromatography (LC)-high | gas flow, and mass accuracy. The AQbD-based quick LC | The quality assessment of oligonucleotide

关键词： analytical quality by design | assay method development | liquid chromatography-high resolution mass spectrometry | Nusinersen | oligonucleotides | liquid chromatography–high resolution mass spectrometry

摘要： chromatography-high resolution mass spectrometry (UHPLC-HRMS | mass spectrometry data were employed to enhance the | © 2024 Elsevier LtdDaily dietary intake | inevitably exposes individuals to various natural toxins | , which may pose potential health threats. Focusing only

关键词： Dietary exposure | Foodstuffs | High-resolution mass spectrometry | Natural toxins | Suspect and nontarget screening

摘要：. Herein, the electrospray ionization-high-resolution | mass spectrometry (ESI-HRMS) was applied to determine | maximum resolution setting was insufficient to | accurate mass and excluding the isobar interference. | Rationale: Stable isotope-labeled organic

关键词： electrospray ionization-high resolution mass spectrometry | isotopic purity | representative isotopolog ion | stable isotope-labeled organic compounds | electrospray ionization‐high resolution mass spectrometry | stable isotope‐labeled organic compounds

摘要：-resolution mass spectrometry. Nine characteristic fragment | mass spectrum database based on ultrahigh-performance | liquid chromatography-quadrupole/orbitrap high | ions were identified by analyzing the mass | mass database. The detection limits of hypoglycemic

关键词： Non-targeted screening | Illegal additive | Characteristic fragment ions | High resolution mass spectrometry | Food safety

摘要：With an aging population, the increased | interest in the monitoring of skeletal diseases such as | osteoporosis led to significant progress in the discovery and | measurement of bone turnover biomarkers since the 2000s | . Multiple markers derived from type I collagen, such as

关键词： affinity chromatography | CTX | high-resolution mass spectrometry | preparative liquid chromatography | proteomics | type I collagen | high‐resolution mass spectrometry

摘要： water samples using High-resolution mass spectrometry | An efficient wastewater treatment plant is | imperative to limit the entry of emerging pollutants (EPs | ) and emerging microbial contaminants (EMCs) in the | river ecosystem. The detection of emerging EPs in

关键词： River Ganga | Municipal and hospital wastewater | Emerging pollutants | Antimicrobial resistance | High-resolution mass spectrometry | Uncultivable AMR pathogens

关键词： Fish | Food authentication | Fish authenticity testing | Food fraud detection | Liquid chromatography-mass spectrometry | Peptide biomarker

摘要： study, we used high-resolution mass spectrometry | Cyprinid herpesvirus 2 (CyHV-2) is the main | pathogen responsible for the development of herpesviral | hematopoietic necrosis disease (HVHND) in crucian carp | (Carassius auratus). The CyHV-2 genome encodes

关键词： Cyprinid herpesvirus 2 | proteogenomics | gene discovery | mass spectrometry

摘要： resolution mass spectrometry, is comprehensively evaluated | methodology based on diagnostic fragment criteria using high | Cathinones (i.e., beta-keto phenyl ethyl | amines) are one of the most numerous and widespread | categories among new psychoactive substances. A selective

关键词： New psychoactive substances | NPS | Synthetic drugs | Cathinones | Bath salts | High-resolution mass spectrometry | HRMS | Orbitrap | PV8 | Alpha-pep...

摘要： high-resolution mass spectrometry (LC-HRMS) to | Sm.ResultsA total of 213 compounds were identified with high | RationaleGentiana urnula Harry Sm is a | frequently utilized traditional Chinese medicine (TCM) with | applications in the treatment of a range of ailments

关键词： compounds classification | compounds identification | Gentiana urnula Harry Sm | LC-HRMS | SIRIUS | LC‐HRMS

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： resolution mass spectrometry (HRMS) approach for accurate | achieved through high* resolution MS. The extracted ion* | proposed a hyphenated liquid chromatography (LC)-high | gas flow, and mass* accuracy. The AQbD-based quick LC* | The quality assessment of oligonucleotide

摘要： chromatography-high* resolution mass spectrometry (UHPLC-HRMS* | mass spectrometry data were employed to enhance the | © 2024 Elsevier LtdDaily dietary intake | inevitably exposes individuals to various natural toxins | , which may pose potential health threats. Focusing only

摘要：. Herein, the electrospray ionization-high-resolution | mass spectrometry (ESI-HRMS) was applied to determine | maximum resolution* setting was insufficient to* | accurate mass* and excluding the isobar interference.* | Rationale: Stable isotope-labeled organic

摘要：-resolution* mass *spectrometry. Nine characteristic fragment | mass spectrum database based on ultrahigh-performance | liquid chromatography-quadrupole/orbitrap high | ions were identified by analyzing the mass | mass database. The detection limits of hypoglycemic