NSTL国家科技图书文献中心

1. Computational Insights on the Assembly of the Dengue Virus Membrane-Capsid-RNA Complex NSTL国家科技图书文献中心

Chaudhuri, Dwaipayan | Majumder, Satyabrata ... - 《The Journal of Membrane Biology》 - 2025,258(1) - 75～96 - 共22页

摘要： multiple copies of the capsid* protein. Experimental* | capsid protein and lipid droplets, indicating a protein | simulations to explore the orientation of the capsid* protein* | capsid protein and RNA, considering the effects of | that the capsid* protein's hydrophobic pocket*

关键词： Dengue virus | Nucleocapsid | MD simulation | Capsid-lipid interaction | Capsid-RNA interaction

2. Tethered release of the pseudorabies virus deubiquitinase from the capsid promotes enzymatic activity NSTL国家科技图书文献中心

Antinone, Sarah E. | Miller, John S.... - 《Journal of Virology》 - 2025,99(1) - e01517-24～e01517-24 - 共23页

摘要： in the interstitial space between the capsid* and* | capsid to the nucleus. To gain insight into the | protein (pUL36), which is stably bound to the capsid | to the capsid* via its N-terminal deubiquitinase* | tethered to the capsid* by the pUL36 C-terminus, by a*

关键词： alphaherpesvirus | pseudorabies virus | PRV | large tegument protein | virion structure | pUL36 | deubiquitinase | DUB | cysteine | capsid

3. Structure of the T=13 capsid of infectious pancreatic necrosis virus (IPNV)-a salmonid birnavirus NSTL国家科技图书文献中心

Munke, Anna | Gamil, Amr Ahmed Abd...... - 《Journal of Virology》 - 2025,99(2) - e01454-24～e01454-24 - 共14页

摘要：), an avibirnavirus. Determining the capsid* structure* | advancing knowledge of its antigenicity, capsid* assembly* | , and possible functional structures. Here, the capsid | capsid protein essential for antigenicity and virulence | , positively charged residues in obstructed capsid* pores at*

关键词： capsid | structure | birnavirus | infectious pancreatic necrosis virus | IPNV | cryogenic electron microscopy | cryo-EM

4. Drug-drug interactions potential with the HIV-1 capsid inhibitor lenacapavir NSTL国家科技图书文献中心

Marzolini, Catia | Gibbons, Sara ... - 《Expert opinion on drug metabolism & toxicology》 - 2025,21(2) - 161～172 - 共12页

摘要： capsid inhibitor administered subcutaneously twice | ,' 'capsid* inhibitor,' 'GS-6207,' and a PubMed search was* | IntroductionLenacapavir is the first HIV-1 | yearly. While lenacapavir is currently only indicated | as salvage therapy, it has the potential to become

关键词： Lenacapavir | capsid inhibitor | drug-drug interactions | long-acting | antiretroviral

5. Evaluation of Three Viral Capsid Integrity qPCR Methods for Wastewater-Based Viral Surveillance NSTL国家科技图书文献中心

Kevill, Jessica L. | Farkas, Kata ... - 《Food and Environmental Virology》 - 2025,17(1) - 共15页

摘要：Capsid Integrity qPCR (CI-qPCR) assays offer a | capsid integrity assays using intercalating dyes. In | promising alternative to cell culture-based infectivity | assays for assessing pathogenic human virus viability | in wastewater. This study compared three CI-qPCR

关键词： Capsid integrity | Environmental surveillance | Pathogen viability | Public health risk | Viral persistence | Wastewater-based epidemiology

6. Isolation of Peptide Ligands for the HIV Capsid Protein p24 by Phage-Display NSTL国家科技图书文献中心

Jerry,Woo | Emily,Orozco ... - 《International journal of peptide research and therapeutics.》 - 2025,31(2) - Article: 32～Article: 32 - 共10页

摘要： detection of p24, the capsid* protein of Human* | Abstract Purpose Isolate renewable and cost | -efficient affinity reagents that will facilitate the | Immunodeficiency Virus (HIV), by screening phage-displayed | combinatorial peptide libraries and identifying peptide

关键词： Combinatorial peptides | HIV | p24 capsid protein | Phage display

7. Adaptive immune response to a wild boar-derived recombinant hepatitis e virus capsid protein challenge in pigs NSTL国家科技图书文献中心

Grigas, Juozas | Spancerniene, Ugne ... - 《Vaccine》 - 2025,44 - 126561～126561 - 共6页

摘要： 112-608 wild boar-derived HEV-3 capsid* protein* | Hepatitis E virus genotype 3 (HEV-3) is a | zoonotic pathogen capable of infecting human, porcine | , and other animal hosts. Despite a broad host range | and abundance of species that act as reservoirs for

关键词： Hepatitis E virus | Capsid protein | Open reading frame 2 | Pig | Antibody | Peripheral blood mononuclear cells

8. Discovery of three novel neutralizing antibody epitopes on the human astrovirus capsid spike and mechanistic insights into virus neutralization NSTL国家科技图书文献中心

Lanning, Sarah | Aguilar-Hernandez, N...... - 《Journal of Virology》 - 2025,99(2) - e01619-24～e01619-24 - 共22页

摘要： on the capsid* spike and find that while antibodies* | receptor FcRn binding to the capsid* spike. These studies* | inform which regions of the HAstV capsid* can be* | Human astroviruses (HAstVs) are a leading | cause of viral childhood diarrhea that infects nearly

关键词： human astrovirus | capsid | surface antigens | monoclonal antibodies | protein structure-function | X-ray crystallography | cryo-EM | neutralization

9. Autophagy promotes p72 degradation and capsid disassembly during the early phase of African swine fever virus infection NSTL国家科技图书文献中心

Song, Jie | Li, Jiangnan ... - 《Journal of Virology》 - 2025,99(1) - e01701-24～e01701-24 - 共19页

摘要： selectively targets the major capsid* protein p72 within the* | capsid disassembly of ASFV, providing valuable insights | During viral infections, autophagy functions | as a cell-intrinsic defense mechanism by | facilitating the delivery of virions or viral components to

关键词： African swine fever virus | p72 | selective autophagy | Stub1 | HSPA8 | capsid disassembly

10. Structural basis for nuclear import of adeno-associated virus serotype 6 capsid protein NSTL国家科技图书文献中心

Hoad, Mikayla | Nematollahzadeh, Sep...... - 《Journal of Virology》 - 2025,99(1) - e01345-24～e01345-24 - 共17页

摘要： capsid protein can localize to the nucleus of mammalian | insights into the interaction between the AAV6 VP1 capsid | Adeno-associated viruses (AAVs) are the most | extensively researched viral vectors for gene therapy | globally. The AAV viral protein 1 (VP1) N-terminus

摘要： multiple copies of the capsid* protein. Experimental* | capsid protein and lipid droplets, indicating a protein | simulations to explore the orientation of the capsid* protein* | capsid protein and RNA, considering the effects of | that the capsid* protein's hydrophobic pocket*

关键词： Dengue virus | Nucleocapsid | MD simulation | Capsid-lipid interaction | Capsid-RNA interaction

摘要： in the interstitial space between the capsid* and* | capsid to the nucleus. To gain insight into the | protein (pUL36), which is stably bound to the capsid | to the capsid* via its N-terminal deubiquitinase* | tethered to the capsid* by the pUL36 C-terminus, by a*

关键词： alphaherpesvirus | pseudorabies virus | PRV | large tegument protein | virion structure | pUL36 | deubiquitinase | DUB | cysteine | capsid

关键词： capsid | structure | birnavirus | infectious pancreatic necrosis virus | IPNV | cryogenic electron microscopy | cryo-EM

摘要： capsid inhibitor administered subcutaneously twice | ,' 'capsid* inhibitor,' 'GS-6207,' and a PubMed search was* | IntroductionLenacapavir is the first HIV-1 | yearly. While lenacapavir is currently only indicated | as salvage therapy, it has the potential to become

关键词： Lenacapavir | capsid inhibitor | drug-drug interactions | long-acting | antiretroviral

摘要：Capsid Integrity qPCR (CI-qPCR) assays offer a | capsid integrity assays using intercalating dyes. In | promising alternative to cell culture-based infectivity | assays for assessing pathogenic human virus viability | in wastewater. This study compared three CI-qPCR

关键词： Capsid integrity | Environmental surveillance | Pathogen viability | Public health risk | Viral persistence | Wastewater-based epidemiology

摘要： detection of p24, the capsid* protein of Human* | Abstract Purpose Isolate renewable and cost | -efficient affinity reagents that will facilitate the | Immunodeficiency Virus (HIV), by screening phage-displayed | combinatorial peptide libraries and identifying peptide

关键词： Combinatorial peptides | HIV | p24 capsid protein | Phage display

摘要： 112-608 wild boar-derived HEV-3 capsid* protein* | Hepatitis E virus genotype 3 (HEV-3) is a | zoonotic pathogen capable of infecting human, porcine | , and other animal hosts. Despite a broad host range | and abundance of species that act as reservoirs for

关键词： Hepatitis E virus | Capsid protein | Open reading frame 2 | Pig | Antibody | Peripheral blood mononuclear cells

摘要： on the capsid* spike and find that while antibodies* | receptor FcRn binding to the capsid* spike. These studies* | inform which regions of the HAstV capsid* can be* | Human astroviruses (HAstVs) are a leading | cause of viral childhood diarrhea that infects nearly

关键词： human astrovirus | capsid | surface antigens | monoclonal antibodies | protein structure-function | X-ray crystallography | cryo-EM | neutralization

摘要： selectively targets the major capsid* protein p72 within the* | capsid disassembly of ASFV, providing valuable insights | During viral infections, autophagy functions | as a cell-intrinsic defense mechanism by | facilitating the delivery of virions or viral components to

关键词： African swine fever virus | p72 | selective autophagy | Stub1 | HSPA8 | capsid disassembly

摘要： capsid protein can localize to the nucleus of mammalian | insights into the interaction between the AAV6 VP1 capsid | Adeno-associated viruses (AAVs) are the most | extensively researched viral vectors for gene therapy | globally. The AAV viral protein 1 (VP1) N-terminus

关键词： nuclear import | adeno-associated virus | importin | karyopherin

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： multiple copies of the capsid protein. Experimental | capsid protein and lipid droplets, indicating a protein | simulations to explore the orientation of the capsid protein | capsid protein and RNA, considering the effects of | that the capsid protein's hydrophobic pocket

关键词： Dengue virus | Nucleocapsid | MD simulation | Capsid-lipid interaction | Capsid-RNA interaction

摘要： in the interstitial space between the capsid and | capsid to the nucleus. To gain insight into the | protein (pUL36), which is stably bound to the capsid | to the capsid via its N-terminal deubiquitinase | tethered to the capsid by the pUL36 C-terminus, by a

关键词： alphaherpesvirus | pseudorabies virus | PRV | large tegument protein | virion structure | pUL36 | deubiquitinase | DUB | cysteine | capsid

摘要：), an avibirnavirus. Determining the capsid structure | advancing knowledge of its antigenicity, capsid assembly | , and possible functional structures. Here, the capsid | capsid protein essential for antigenicity and virulence | , positively charged residues in obstructed capsid pores at

关键词： capsid | structure | birnavirus | infectious pancreatic necrosis virus | IPNV | cryogenic electron microscopy | cryo-EM

摘要： capsid inhibitor administered subcutaneously twice | ,' 'capsid inhibitor,' 'GS-6207,' and a PubMed search was | IntroductionLenacapavir is the first HIV-1 | yearly. While lenacapavir is currently only indicated | as salvage therapy, it has the potential to become

关键词： Lenacapavir | capsid inhibitor | drug-drug interactions | long-acting | antiretroviral

摘要：Capsid Integrity qPCR (CI-qPCR) assays offer a | capsid integrity assays using intercalating dyes. In | promising alternative to cell culture-based infectivity | assays for assessing pathogenic human virus viability | in wastewater. This study compared three CI-qPCR

关键词： Capsid integrity | Environmental surveillance | Pathogen viability | Public health risk | Viral persistence | Wastewater-based epidemiology

摘要： detection of p24, the capsid protein of Human | Abstract Purpose Isolate renewable and cost | -efficient affinity reagents that will facilitate the | Immunodeficiency Virus (HIV), by screening phage-displayed | combinatorial peptide libraries and identifying peptide

关键词： Combinatorial peptides | HIV | p24 capsid protein | Phage display

摘要： 112-608 wild boar-derived HEV-3 capsid protein | Hepatitis E virus genotype 3 (HEV-3) is a | zoonotic pathogen capable of infecting human, porcine | , and other animal hosts. Despite a broad host range | and abundance of species that act as reservoirs for

关键词： Hepatitis E virus | Capsid protein | Open reading frame 2 | Pig | Antibody | Peripheral blood mononuclear cells

摘要： on the capsid spike and find that while antibodies | receptor FcRn binding to the capsid spike. These studies | inform which regions of the HAstV capsid can be | Human astroviruses (HAstVs) are a leading | cause of viral childhood diarrhea that infects nearly

关键词： human astrovirus | capsid | surface antigens | monoclonal antibodies | protein structure-function | X-ray crystallography | cryo-EM | neutralization

摘要： selectively targets the major capsid protein p72 within the | capsid disassembly of ASFV, providing valuable insights | During viral infections, autophagy functions | as a cell-intrinsic defense mechanism by | facilitating the delivery of virions or viral components to

关键词： African swine fever virus | p72 | selective autophagy | Stub1 | HSPA8 | capsid disassembly

摘要： capsid protein can localize to the nucleus of mammalian | insights into the interaction between the AAV6 VP1 capsid | Adeno-associated viruses (AAVs) are the most | extensively researched viral vectors for gene therapy | globally. The AAV viral protein 1 (VP1) N-terminus

关键词： nuclear import | adeno-associated virus | importin | karyopherin

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： multiple copies of the capsid* protein. Experimental* | capsid protein and lipid droplets, indicating a protein | simulations to explore the orientation of the capsid* protein* | capsid protein and RNA, considering the effects of | that the capsid* protein's hydrophobic pocket*

摘要： in the interstitial space between the capsid* and* | capsid to the nucleus. To gain insight into the | protein (pUL36), which is stably bound to the capsid | to the capsid* via its N-terminal deubiquitinase* | tethered to the capsid* by the pUL36 C-terminus, by a*

摘要： capsid inhibitor administered subcutaneously twice | ,' 'capsid* inhibitor,' 'GS-6207,' and a PubMed search was* | IntroductionLenacapavir is the first HIV-1 | yearly. While lenacapavir is currently only indicated | as salvage therapy, it has the potential to become

摘要： detection of p24, the capsid* protein of Human* | Abstract Purpose Isolate renewable and cost | -efficient affinity reagents that will facilitate the | Immunodeficiency Virus (HIV), by screening phage-displayed | combinatorial peptide libraries and identifying peptide

摘要： 112-608 wild boar-derived HEV-3 capsid* protein* | Hepatitis E virus genotype 3 (HEV-3) is a | zoonotic pathogen capable of infecting human, porcine | , and other animal hosts. Despite a broad host range | and abundance of species that act as reservoirs for

摘要： on the capsid* spike and find that while antibodies* | receptor FcRn binding to the capsid* spike. These studies* | inform which regions of the HAstV capsid* can be* | Human astroviruses (HAstVs) are a leading | cause of viral childhood diarrhea that infects nearly

摘要： selectively targets the major capsid* protein p72 within the* | capsid disassembly of ASFV, providing valuable insights | During viral infections, autophagy functions | as a cell-intrinsic defense mechanism by | facilitating the delivery of virions or viral components to