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1. Theranostic Rhenium Complexes as Suborganelle-Targeted Copper Ionophores To Stimulate Cuproptosis for Cancer Immunotherapy NSTL国家科技图书文献中心

Ling, Yu-Yi |  Shen, Qing-Hua... -  《ACS applied materials & interfaces》 - 2025,17(10) - 15237~15249 - 共13页

摘要:) as suborganelle-targeted copper ionophores. Among |  cuproptosis is predominantly elicited by cellular copper |  copper homeostasis within mitochondria, we designed a |  copper into mitochondria and the Golgi apparatus and |  especially enrich copper into mitochondria. Consequently
关键词: cuproptosis |  copper ionophores |  immunotherapy |  rhenium complex |  mitochondria

2. Involvement of copper in cell death and cancer NSTL国家科技图书文献中心

Xie, Jiahao |  Su, Yue... -  《Apoptosis》 - 2025,30(1/2) - 488~505 - 共18页

摘要:Copper (cu) is an essential micronutrient |  copper levels and/or alterations in the overall |  distribution of copper. Modulating local or systemic copper |  examination of copper metabolism in both physiological and |  copper ions can effectively target and stimulate tumor
关键词: Copper |  Cuproptosis |  Copper ionophores |  Apoptosis |  Cancer

3. Cinobufagin treatments suppress tumor growth by enhancing the expression of cuproptosis-related genes in liver cancer NSTL国家科技图书文献中心

Amelimojarad, Mandan... |  Amelimojarad, Melika... -  《Naunyn-Schmiedeberg's Archives of Pharmacology》 - 2025,398(2) - 1575~1582 - 共8页

摘要: oxygen species (ROS) production, copper ionophores |  regulated cell death triggered by excess copper (Cu | , especially by increasing copper transporters CTR1, CTR2 | , and LIAS and downregulation of copper efflux |  while reduced intracellular copper chelator
关键词: Cinobufagin |  Cuproptosis |  Liver cancer

4. A cuproptosis-based nanomedicine suppresses triple negative breast cancers by regulating tumor microenvironment and eliminating cancer stem cells NSTL国家科技图书文献中心

Xiao, Chen |  Wang, Xing... -  《Biomaterials》 - 2025,313 - 共19页

摘要: stabilizing copper ionophores CuET nanocrystals with |  depends on delivering copper ions into mitochondria to | Cuproptosis is a new kind of cell death that |  trigger the aggradation of tricarboxylic acid (TCA | ) cycle proteins and has been observed in various cancer
关键词: Cuproptosis |  ROS-Responsiveness |  Tumor microenvironment |  Cancer stem cells

5. PDE3B regulates KRT6B and increases the sensitivity of bladder cancer cells to copper ionophores NSTL国家科技图书文献中心

Yuankang,Feng |  Zhenlin,Huang... -  《Naunyn-Schmiedeberg's Archives of Pharmacology》 - 2024,397(7) - 4911~4925 - 共15页

摘要: the sensitivity of bladder cancer cells to copper |  ionophores. | Abstract Cuproptosis is a new Cu-dependent |  programmed cell death manner that has shown regulatory |  functions in many tumor types, however, its mechanism in
关键词: Cuproptosis |  Bladder cancer |  PDE3B |  Thiram |  Epithelial–mesenchymal transition

6. Photoinduced Cuproptosis with Tumor‐Specific for Metastasis‐Inhibited Cancer Therapy NSTL国家科技图书文献中心

Jiazhu Zheng |  Haoying Ge... -  《Small》 - 2024,20(10) - n/a~n/a - 共10页 - 被引量:6

摘要: study, exploiting the chemical properties of copper |  ionophores and the tumor microenvironment, a novel method |  is developed for controlling the valence of copper | Abstract Cuproptosis is a novel form of |  regulated cell death which guarantees to increase the
关键词: cancer therapy |  copper ionophores |  cuproptosis |  photosensitizer |  tumor microenvironment

7. Copper(II) Coordination Complexes: The Synthesis and Application as Ionophores for Nitrate Detection in Water Systems NSTL国家科技图书文献中心

Leboh Solange, Ngang... -  Chemistry.;Analytica... -  M.S. -  Yue, Yanfeng |  Ozbay, Gulnihal - 2024, - 1~73 - 共73页

摘要: synthesized the Schiff-base copper complex and further used |  them as ionophores for nitrate detection. First, we | Nitrate ion as a primary nutrient for plants |  and algae growth in water, can cause diseases in |  humans, eutrophication, and cattle abortion when its
关键词: Ionophore |  Nitrate detection |  Potentiometry |  Schiff-base copper complex |  Water quality monitoring

8. S-S bridged Schiff bases as versatile ionophores: Synthesis and application for electrochemical sensing of Copper(II) and Mercury(II) NSTL国家科技图书文献中心

Kaur, Sarbjeet |  Kaur, Jaspreet... -  《Analytica chimica acta》 - 2024,1287 - ARTN 342122~ - 共11页 - 被引量:3

摘要:Schiff base derivates (3, 4 and 5) comprising |  pseudo cavity with different heteroatoms (O, N and S | ) were designed, synthesized and explored for their |  detection behaviour towards diverse metal ions. In UV and |  fluorescence studies, all three receptors exhibited sensitive
关键词: Schiff base |  Pseudo cavity |  Dual sensor |  Voltammetric sensor |  Carbon paste electrode |  FLUORESCENT SENSOR |  CU2+ |  IONS |  TOXICITY |  HG2+

9. Disulfiram mediated anti-tumour effect in pituitary neuroendocrine tumours by inducing cuproptosis NSTL国家科技图书文献中心

Huang N. |  Feng Y.... -  《International immunopharmacology》 - 2024,134 - 112159~112159 - 共6页

摘要:-throughput drug screening, and a class of copper ionophores |  effect of these copper ionophores on AtT20, GH3, and |  copper ionophores as a potential class of drugs for |  depends on the presence of copper. Additionally, we | ? 2024Context: Medical treatment plays a
关键词: Cuproptosis |  Disulfiram |  High-throughput screening |  Pituitary neuroendocrine tumour

10. Cuproptosis: A novel therapeutic target for overcoming cancer drug resistance NSTL国家科技图书文献中心

Chen Y. |  Zhang J.... -  《Drug resistance updates: reviews and commentaries in antimicrobial and anticancer chemotherapy》 - 2024,72 - 101018~101018 - 共6页 - 被引量:42

摘要: (copper chelators, copper ionophores, and copper |  complexes-based agents and copper ionophores to subdue |  identified form of cell death driven by copper. Recently | , the role of copper and copper triggered cell death |  potential for cancer therapy. Copper-based treatment
关键词: Cancer |  Copper |  Cuproptosis |  Drug resistance |  Nanoparticles
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