NSTL国家科技图书文献中心

1. Advance on the effects of algal carotenoids on inflammatory signaling pathways NSTL国家科技图书文献中心

Wang, Yudi | Geng, Xinrong ... - 《European Journal of Medicinal Chemistry》 - 2025,281 - 117020～117020 - 共13页

摘要： discussed the mechanism of carotenoids targeting* those* | , with a focus on the targets and targeting* effects of* | The development of inflammation has an | indispensable importance in the self-protection of the human | body. However, over-inflammation may damage human

关键词： Algal carotenoids | Inflammatory signaling pathways | Targeting effect

2. Anticancer Effect of C19-Position Substituted Geldanamycin Derivatives Targeting NRF2-NQO1-activated Esophageal Squamous Cell Carcinoma NSTL国家科技图书文献中心

Oshikiri, Hiroyuki | Taguchi, Keiko ... - 《Molecular and Cellular Biology》 - 2025,45(2) - 79～97 - 共19页

摘要：In esophageal squamous cell carcinoma, genetic | activation of NRF2 increases resistance to chemotherapy and | radiotherapy, which results in a significantly worse | prognosis for patients. Therefore NRF2-activated cancers | create an urgent clinical need to identify new

关键词： ESCC | NRF2-NQO1-activated cancer | NQO1 | C19-position substituted geldanamycin derivatives | HSP90

3. Neuroprotective effect of Bacillus subtilis in haloperidol induced rat model, targeting the microbiota-gut-brain axis NSTL国家科技图书文献中心

Rout, Monalisa | Kar, Durga Madhab ... - 《Journal of molecular histology》 - 2025,56(1) - Article: 18～Article: 18 - 共18页

摘要： disease by targeting* the gut-brain axis.* | Functional microbes regulate Parkinson's | disease (PD), according to contemporary research. The | mechanism by which probiotics (PBT) improve PD was not | fully explored yet. We examined the antioxidant impact

关键词： Gut | Probiotic | Inflammation | Microbiota | Parkinson's

4. Effect of reaction temperatures on optical properties of clove buds derived carbon dots for targeting nucleolus NSTL国家科技图书文献中心

Pandey, Anurag Kumar | Nath, Tapan Kumar ... - 《Journal of industrial and engineering chemistry》 - 2025,141 - 441～455 - 共15页

摘要：This work pacts with a simple and | environmentally friendly hydrothermal method to synthesize clove | buds derived carbon dots (CCDs) at different | temperatures. Five CCDs samples were synthesized at different | reaction temperatures ranging from 120 degrees C to 200

关键词： Clove buds derived carbon dots | Reaction temperature | Fluorescent probe | Nucleolus imaging | Antioxidant

5. PEGylated retinoate prodrug self-assembled nanomicelles loaded with triptolide for targeting treatment of rheumatoid arthritis and side effect attenuation NSTL国家科技图书文献中心

Zhu, Huanhuan | Wang, Zhenzhen ... - 《Colloids and Surfaces,B.Biointerfaces》 - 2025,251 - 共11页

摘要： arthritis and synergetic attenuation of side effect. | Triptolide (TP, an active ingredient from | Tripterygium wilfordii) demonstrates significant efficacy in | treating rheumatoid arthritis, but its low | bioavailability and multi-organ toxicity limit its application

关键词： Triptolide | Retinoic acid | Rheumatoid arthritis | Nanomicelles | Toxicity

6. Effect of starch molecular weight on the colon-targeting delivery and promoting GLP-1 secretion of starch-lecithin complex nanoparticles NSTL国家科技图书文献中心

Wang K. | Chi C.... - 《Food hydrocolloids》 - 2025,158(Jan.) - 1.1～1.13 - 共13页

摘要： administration, colon-targeting* delivery systems should be* | capacity (59.25%) and colon-targeting* capacity (49.18* | %) primarily through -LG targeting* released in colon in the* | -targeting* delivery systems for use in stimulating GLP-1* | © 2024 Elsevier Ltd-lactoglobulin (-LG) could

关键词： Colon-targeting | Lecithin | Nanoparticles | OSA starch | -Lactoglobulin

7. [Retracted] Promoter methylation of RASSF1A modulates the effect of the microtubule‑targeting agent docetaxel in breast cancer NSTL国家科技图书文献中心

Eun Young Gil | Uk Hyun Jo ... - 《International journal of oncology》 - 2025,66(5) - Article Number: 39～Article Number: 39 - 共1页

摘要：Following the publication of this paper, and a | corrigendum that was subsequently published to take account | of anomalies that were identified with the assembly | of western blot data in Fig. 5B (doi: 10.3892/ijo | .2017.3900), a concerned reader drew to the Editor's

关键词： RASSF1A; breast cancer; cyclin B1; docetaxel; methylation.

8. Size effect of magnetic core-shell nanodrugs on efficiency of targeted cell uptake and drug delivery NSTL国家科技图书文献中心

Fei, Weiwei | Guo, Jia ... - 《Colloids and Surfaces,A.Physicochemical and Engineering Aspects》 - 2025,716 - 共11页

摘要： targeting drug delivery. However, little research has been | done on the effect* of nanoparticle size on the* | targeting agent binding, drug loading and releasing | polymerization. Transferrin (Tf) was used as a targeting* ligand* | of nanoparticle size on the targeting* agent*

关键词： Magnetic nanoparticles | Size effect | Tf immobilization | Drug loading | Cell targeting | Anticancer effect

9. Novel Anti-Tumor Effect of Natural Products from Aloe vera Resin and their In-Vitro / In-Silico Targeting Mechanism of Carbonic Anhydrase-II and IX NSTL国家科技图书文献中心

Khan, Majid | Halim, Sobia Ahsan ... - 《Chemistry & biodiversity》 - 2025,22(3) - n/a～n/a - 共14页

摘要： cytotoxic effect* on BJ (normal) cell line, all the* | Human carbonic anhydrase (hCA) plays a vital | role in the development and progression of tumors in | hypoxic conditions. Herein we report the hCA-II and hCA | -IX activities of natural products isolated from

关键词： Human carbonic anhydrases-II and -IX | Aloe vera | In-vitro enzyme inhibition | Anti-proliferative | Molecular docking

10. A study of the role of androgen receptor and androgen receptor variant 7 in TNBC patients and the effect of their targeting by Enzalutamide and EPI-001 in MDA-MB-231 NSTL国家科技图书文献中心

Ali, Belal M. | El-Abhar, Hanan S.... - 《The Journal of Steroid Biochemistry and Molecular Biology》 - 2025,245 - 106636～106636 - 共11页

摘要： and ELISA were employed to assess the effect* of AR* | least in part by targeting* ROCK/NF-KB/c-Myc axis.* | The lack of targeted therapy for triple | -negative breast cancer (TNBC) is among the mainsprings of | its poor prognosis. This study aimed to elucidate

摘要： discussed the mechanism of carotenoids targeting* those* | , with a focus on the targets and targeting* effects of* | The development of inflammation has an | indispensable importance in the self-protection of the human | body. However, over-inflammation may damage human

关键词： Algal carotenoids | Inflammatory signaling pathways | Targeting effect

摘要：In esophageal squamous cell carcinoma, genetic | activation of NRF2 increases resistance to chemotherapy and | radiotherapy, which results in a significantly worse | prognosis for patients. Therefore NRF2-activated cancers | create an urgent clinical need to identify new

关键词： ESCC | NRF2-NQO1-activated cancer | NQO1 | C19-position substituted geldanamycin derivatives | HSP90

摘要： disease by targeting* the gut-brain axis.* | Functional microbes regulate Parkinson's | disease (PD), according to contemporary research. The | mechanism by which probiotics (PBT) improve PD was not | fully explored yet. We examined the antioxidant impact

关键词： Gut | Probiotic | Inflammation | Microbiota | Parkinson's

摘要：This work pacts with a simple and | environmentally friendly hydrothermal method to synthesize clove | buds derived carbon dots (CCDs) at different | temperatures. Five CCDs samples were synthesized at different | reaction temperatures ranging from 120 degrees C to 200

关键词： Clove buds derived carbon dots | Reaction temperature | Fluorescent probe | Nucleolus imaging | Antioxidant

摘要： arthritis and synergetic attenuation of side effect. | Triptolide (TP, an active ingredient from | Tripterygium wilfordii) demonstrates significant efficacy in | treating rheumatoid arthritis, but its low | bioavailability and multi-organ toxicity limit its application

关键词： Triptolide | Retinoic acid | Rheumatoid arthritis | Nanomicelles | Toxicity

关键词： Colon-targeting | Lecithin | Nanoparticles | OSA starch | -Lactoglobulin

摘要：Following the publication of this paper, and a | corrigendum that was subsequently published to take account | of anomalies that were identified with the assembly | of western blot data in Fig. 5B (doi: 10.3892/ijo | .2017.3900), a concerned reader drew to the Editor's

关键词： RASSF1A; breast cancer; cyclin B1; docetaxel; methylation.

摘要： targeting drug delivery. However, little research has been | done on the effect* of nanoparticle size on the* | targeting agent binding, drug loading and releasing | polymerization. Transferrin (Tf) was used as a targeting* ligand* | of nanoparticle size on the targeting* agent*

关键词： Magnetic nanoparticles | Size effect | Tf immobilization | Drug loading | Cell targeting | Anticancer effect

摘要： cytotoxic effect* on BJ (normal) cell line, all the* | Human carbonic anhydrase (hCA) plays a vital | role in the development and progression of tumors in | hypoxic conditions. Herein we report the hCA-II and hCA | -IX activities of natural products isolated from

关键词： Human carbonic anhydrases-II and -IX | Aloe vera | In-vitro enzyme inhibition | Anti-proliferative | Molecular docking

摘要： and ELISA were employed to assess the effect* of AR* | least in part by targeting* ROCK/NF-KB/c-Myc axis.* | The lack of targeted therapy for triple | -negative breast cancer (TNBC) is among the mainsprings of | its poor prognosis. This study aimed to elucidate

关键词： Androgen receptor | Androgen receptor splice variant 7 | Enzalutamide | EPI-001 | Triple-negative breast cancer | Metastasis

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： discussed the mechanism of carotenoids targeting those | , with a focus on the targets and targeting effects of | The development of inflammation has an | indispensable importance in the self-protection of the human | body. However, over-inflammation may damage human

关键词： Algal carotenoids | Inflammatory signaling pathways | Targeting effect

摘要：In esophageal squamous cell carcinoma, genetic | activation of NRF2 increases resistance to chemotherapy and | radiotherapy, which results in a significantly worse | prognosis for patients. Therefore NRF2-activated cancers | create an urgent clinical need to identify new

关键词： ESCC | NRF2-NQO1-activated cancer | NQO1 | C19-position substituted geldanamycin derivatives | HSP90

摘要： disease by targeting the gut-brain axis. | Functional microbes regulate Parkinson's | disease (PD), according to contemporary research. The | mechanism by which probiotics (PBT) improve PD was not | fully explored yet. We examined the antioxidant impact

关键词： Gut | Probiotic | Inflammation | Microbiota | Parkinson's

摘要：This work pacts with a simple and | environmentally friendly hydrothermal method to synthesize clove | buds derived carbon dots (CCDs) at different | temperatures. Five CCDs samples were synthesized at different | reaction temperatures ranging from 120 degrees C to 200

关键词： Clove buds derived carbon dots | Reaction temperature | Fluorescent probe | Nucleolus imaging | Antioxidant

摘要： arthritis and synergetic attenuation of side effect. | Triptolide (TP, an active ingredient from | Tripterygium wilfordii) demonstrates significant efficacy in | treating rheumatoid arthritis, but its low | bioavailability and multi-organ toxicity limit its application

关键词： Triptolide | Retinoic acid | Rheumatoid arthritis | Nanomicelles | Toxicity

摘要： administration, colon-targeting delivery systems should be | capacity (59.25%) and colon-targeting capacity (49.18 | %) primarily through -LG targeting released in colon in the | -targeting delivery systems for use in stimulating GLP-1 | © 2024 Elsevier Ltd-lactoglobulin (-LG) could

关键词： Colon-targeting | Lecithin | Nanoparticles | OSA starch | -Lactoglobulin

摘要：Following the publication of this paper, and a | corrigendum that was subsequently published to take account | of anomalies that were identified with the assembly | of western blot data in Fig. 5B (doi: 10.3892/ijo | .2017.3900), a concerned reader drew to the Editor's

关键词： RASSF1A; breast cancer; cyclin B1; docetaxel; methylation.

摘要： targeting drug delivery. However, little research has been | done on the effect of nanoparticle size on the | targeting agent binding, drug loading and releasing | polymerization. Transferrin (Tf) was used as a targeting ligand | of nanoparticle size on the targeting agent

关键词： Magnetic nanoparticles | Size effect | Tf immobilization | Drug loading | Cell targeting | Anticancer effect

摘要： cytotoxic effect on BJ (normal) cell line, all the | Human carbonic anhydrase (hCA) plays a vital | role in the development and progression of tumors in | hypoxic conditions. Herein we report the hCA-II and hCA | -IX activities of natural products isolated from

关键词： Human carbonic anhydrases-II and -IX | Aloe vera | In-vitro enzyme inhibition | Anti-proliferative | Molecular docking

摘要： and ELISA were employed to assess the effect of AR | least in part by targeting ROCK/NF-KB/c-Myc axis. | The lack of targeted therapy for triple | -negative breast cancer (TNBC) is among the mainsprings of | its poor prognosis. This study aimed to elucidate

关键词： Androgen receptor | Androgen receptor splice variant 7 | Enzalutamide | EPI-001 | Triple-negative breast cancer | Metastasis

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： discussed the mechanism of carotenoids targeting* those* | , with a focus on the targets and targeting* effects of* | The development of inflammation has an | indispensable importance in the self-protection of the human | body. However, over-inflammation may damage human

摘要： disease by targeting* the gut-brain axis.* | Functional microbes regulate Parkinson's | disease (PD), according to contemporary research. The | mechanism by which probiotics (PBT) improve PD was not | fully explored yet. We examined the antioxidant impact

摘要： targeting drug delivery. However, little research has been | done on the effect* of nanoparticle size on the* | targeting agent binding, drug loading and releasing | polymerization. Transferrin (Tf) was used as a targeting* ligand* | of nanoparticle size on the targeting* agent*

摘要： cytotoxic effect* on BJ (normal) cell line, all the* | Human carbonic anhydrase (hCA) plays a vital | role in the development and progression of tumors in | hypoxic conditions. Herein we report the hCA-II and hCA | -IX activities of natural products isolated from

摘要： and ELISA were employed to assess the effect* of AR* | least in part by targeting* ROCK/NF-KB/c-Myc axis.* | The lack of targeted therapy for triple | -negative breast cancer (TNBC) is among the mainsprings of | its poor prognosis. This study aimed to elucidate