NSTL国家科技图书文献中心

1. Kat7 accelerates osteoarthritis disease progression through the TLR4/NF-κB signaling pathway NSTL国家科技图书文献中心

Liu, Zhen | Qiu, Lijie ... - 《Journal of molecular medicine》 - 2025,103(3) - 273～284 - 共12页

摘要： the TLR4/NF-kappa* B signaling pathway, and | inhibition of this pathway reverses the catabolic effects* | Osteoarthritis (OA) is a common degenerative | bone and joint disease with an unclear pathogenesis | . Our study identified that the histone

关键词： Osteoarthritis | Histone acetyl transferase | Kat7 | TLR4/NF-kappa B signaling pathway | Cartilage metabolism

2. Exosomes derived from human umbilical cord mesenchymal stem cells decrease neuroinflammation and facilitate the restoration of nerve function in rats suffering from intracerebral hemorrhage NSTL国家科技图书文献中心

Nan, Chengrui | Zhang, Yan ... - 《Molecular and Cellular Biochemistry》 - 2025,480(1) - 309～323 - 共15页

摘要： the TLR4/NF-kappa* B signaling pathway. This study | model. The expression of TLR4/NF-kappa B signaling | of TLR4, NF-kappa B/P65, and p-P65, reduced the* | transcription, thereby suppressing the TLR4/NF-kappa* B* | signaling pathway. We can conclude that hUCMSC-ex

关键词： Intracerebral hemorrhage | Human umbilical cord mesenchymal stem cells | Exosomes | Inflammation | TLR4/NF-kappa B

3. Engeletin attenuates the inflammatory response via inhibiting TLR4-NFκB signaling pathway in Crohn's disease-like colitis NSTL国家科技图书文献中心

Wei, Ziyun | Ni, Xiao ... - 《Journal of Ethnopharmacology》 - 2025,336 - 118733～118733 - 共11页

摘要：, as well as the TLR4-NF kappa B signaling pathway | inflammatory cytokines. TLR4-NF kappa B signaling pathway | gene expression and TLR4-NF kappa* B pathway. Flow* | ENG and TLR4. Conclusion: ENG has been proven to | , especially TLR4, may be the target of ENG. These data offer

关键词： Engeletin | CD-Like colitis | Macrophages | M1 polarization | NF-kappa B signaling

4. Epimedium polysaccharides ameliorate ulcerative colitis by inhibiting oxidative stress and regulating autophagy NSTL国家科技图书文献中心

Zhao, Linxian | Jiang, Tao ... - 《Journal of the Science of Food and Agriculture》 - 2025,105(4) - 2655～2670 - 共16页

摘要： receptor 4/nuclear factor-kappa* B (TLR4/NF-kappa B* | -induced UC through the inhibition of the TLR4/NF-kappa* B* | ) signaling* pathway and to alleviate oxidative stress* | signaling pathway, regulation of the Keap1/Nrf2 pathway | (Keap1/Nrf2) pathway. Notably, EPS failed to exert

关键词： ulcerative colitis | Epimedium polysaccharides | TLR4/NF-kappa B | oxidative stress | autophagy | TLR4/NF‐κB

5. Targeting TLR4/NF-κB signaling, oxidative stress, and apoptosis by farnesol mitigates cadmium-induced testicular toxicity in rats NSTL国家科技图书文献中心

Hassanein, Emad H. M... | Alotaibi, Mohammed F...... - 《Tissue and Cell》 - 2025,94 - 102813～102813 - 共11页

摘要： TLR4/NF-kappa B signaling and diminished antioxidants | , suppression of TLR4/NF kappa* B signaling, and inhibition of* | , and IL-6) and suppression of the TLR4/NF-kappa* B* | signaling pathway. FAR inhibited testicular apoptosis by | Cadmium (Cd) is a highly toxic heavy metal

关键词： Farnesol | Cadmium | Testis | Oxidative stress | Inflammation

6. Ameliorating immune-dependent inflammation and apoptosis by targeting TLR4/MYD88/NF-κB pathway by celastrol mitigates the diabetic reproductive dysfunction NSTL国家科技图书文献中心

Faheem, Heba | Alawadhi, Rana ... - 《Physiological genomics》 - 2025,57(3) - 103～114 - 共12页

摘要： TLR4/MyD88/NF-kappa B signaling cascade pathways | kappa B (NF-kappa B), and myeloid differentiation | celastrol significantly reduced TLR4, MyD88, and NF-kappa | relative toll-like receptor 4 (TLR4), nuclear factor | B expressions, and the levels of inflammatory

关键词： celastrol | diabetic testicular dysfunction | TLR4/MYD88/NF-kappa B signaling pathway

7. Bioassay-guided and DeepSAT plus SMART-driven identification of hepatoprotective phenolics from the fruits of Phyllanthus emblica NSTL国家科技图书文献中心

Liang, Zhenzhen | Li, Sheng ... - 《Fitoterapia》 - 2025,182 - 共10页

摘要：-alcoholic liver injury effect via the TLR4/NF-kappa* B* | signaling pathway. | To explore potential protective effects of | natural products against alcohol-induced liver disease | , a bioactivitydriven approach and HSQC-based

关键词： Phenolics constituents | Targeted isolation | Alcohol liver injury | Network pharmacology

8. Involvement of circ_0029407 in Caerulein-Evoked Cytotoxicity in Human Pancreatic Cells via the miR-579-3p/TLR4/NF-κB Pathway NSTL国家科技图书文献中心

Lu, Xingwen | Shi, Caiyan ... - 《Molecular biotechnology》 - 2025,67(5) - 1978～1990 - 共13页

摘要： regulated the TLR4/nuclear factor NF-kappaB (NF-kappa* B* | pancreatic cells at least in part via the TLR4/NF-kappa* B* | signaling pathway by functioning as a ceRNA for miR-579-3p. | (miR)-579-3p, and toll-like receptor 4 (TLR4) were | -3p and circ_0029407 or TLR4. Our results indicated

关键词： Acute pancreatitis (AP) | circ_0029407 | miR-579-3p | ceRNA | TLR4/NF-kappa B signaling

9. Anti-inflammatory, anti-colitis, and antioxidant effects of columbianadin against DSS-induced ulcerative colitis in rats via alteration of HO-1/Nrf2 and TLR4-NF-κB signaling pathway NSTL国家科技图书文献中心

Zhang, Yanping | Cao, Ping ... - 《Inflammopharmacology》 - 2025,33(1) - 341～352 - 共12页

摘要： TLR4-NF-kappa B signaling pathway. | /Nrf2 and TLR4-NF-kappa B signaling pathways. Material | (NF-kappa* B), transforming growth factor (TGF-beta* | -gamma, IL-6, IL-1 beta, IL-8, TNF-alpha, NF-kappa* B* | nitric oxide synthetase (iNOS), nuclear factor kappa* B*

关键词： Columbianadin | Ulcerative colitis | Apoptosis | Inflammation | Oxidative stress

10. Signaling Pathways (TNF-α-NF-κB, TLR2-TLR4 as well as ROS-MDA) and Cardiac Damages during Cardiac Surgeries (Coronary stenting, Permanent Pacemaker Implantations, Radiofrequency Ablations) NSTL国家科技图书文献中心

Li, Xia | Zhao, Yongjuan ... - 《Current topics in medicinal chemistry》 - 2025,25(2) - 196～208 - 共13页

摘要：-inflammatory response (TNF-alpha/NF-kappa B signaling pathway | mutual activation of TNF-alpha/NF-kappa B, TLR2/TLR4 | receptor 4 (TLR4), nuclear factor kappa* B (NF-kappa B* | , MDA, TLR2, TLR4, NF-kappa* B, TNF-alpha, and hs-cTnT* | , MDA, TLR2, TLR4, NF-kappa* B, and TNF-alpha predicted*

摘要： the TLR4/NF-kappa* B signaling pathway, and | inhibition of this pathway reverses the catabolic effects* | Osteoarthritis (OA) is a common degenerative | bone and joint disease with an unclear pathogenesis | . Our study identified that the histone

关键词： Osteoarthritis | Histone acetyl transferase | Kat7 | TLR4/NF-kappa B signaling pathway | Cartilage metabolism

摘要： the TLR4/NF-kappa* B signaling pathway. This study | model. The expression of TLR4/NF-kappa B signaling | of TLR4, NF-kappa B/P65, and p-P65, reduced the* | transcription, thereby suppressing the TLR4/NF-kappa* B* | signaling pathway. We can conclude that hUCMSC-ex

关键词： Intracerebral hemorrhage | Human umbilical cord mesenchymal stem cells | Exosomes | Inflammation | TLR4/NF-kappa B

摘要：, as well as the TLR4-NF kappa B signaling pathway | inflammatory cytokines. TLR4-NF kappa B signaling pathway | gene expression and TLR4-NF kappa* B pathway. Flow* | ENG and TLR4. Conclusion: ENG has been proven to | , especially TLR4, may be the target of ENG. These data offer

关键词： Engeletin | CD-Like colitis | Macrophages | M1 polarization | NF-kappa B signaling

摘要： receptor 4/nuclear factor-kappa* B (TLR4/NF-kappa B* | -induced UC through the inhibition of the TLR4/NF-kappa* B* | ) signaling* pathway and to alleviate oxidative stress* | signaling pathway, regulation of the Keap1/Nrf2 pathway | (Keap1/Nrf2) pathway. Notably, EPS failed to exert

关键词： ulcerative colitis | Epimedium polysaccharides | TLR4/NF-kappa B | oxidative stress | autophagy | TLR4/NF‐κB

摘要： TLR4/NF-kappa B signaling and diminished antioxidants | , suppression of TLR4/NF kappa* B signaling, and inhibition of* | , and IL-6) and suppression of the TLR4/NF-kappa* B* | signaling pathway. FAR inhibited testicular apoptosis by | Cadmium (Cd) is a highly toxic heavy metal

关键词： Farnesol | Cadmium | Testis | Oxidative stress | Inflammation

摘要： TLR4/MyD88/NF-kappa B signaling cascade pathways | kappa B (NF-kappa B), and myeloid differentiation | celastrol significantly reduced TLR4, MyD88, and NF-kappa | relative toll-like receptor 4 (TLR4), nuclear factor | B expressions, and the levels of inflammatory

关键词： celastrol | diabetic testicular dysfunction | TLR4/MYD88/NF-kappa B signaling pathway

摘要：-alcoholic liver injury effect via the TLR4/NF-kappa* B* | signaling pathway. | To explore potential protective effects of | natural products against alcohol-induced liver disease | , a bioactivitydriven approach and HSQC-based

关键词： Phenolics constituents | Targeted isolation | Alcohol liver injury | Network pharmacology

摘要： regulated the TLR4/nuclear factor NF-kappaB (NF-kappa* B* | pancreatic cells at least in part via the TLR4/NF-kappa* B* | signaling pathway by functioning as a ceRNA for miR-579-3p. | (miR)-579-3p, and toll-like receptor 4 (TLR4) were | -3p and circ_0029407 or TLR4. Our results indicated

关键词： Acute pancreatitis (AP) | circ_0029407 | miR-579-3p | ceRNA | TLR4/NF-kappa B signaling

摘要： TLR4-NF-kappa B signaling pathway. | /Nrf2 and TLR4-NF-kappa B signaling pathways. Material | (NF-kappa* B), transforming growth factor (TGF-beta* | -gamma, IL-6, IL-1 beta, IL-8, TNF-alpha, NF-kappa* B* | nitric oxide synthetase (iNOS), nuclear factor kappa* B*

关键词： Columbianadin | Ulcerative colitis | Apoptosis | Inflammation | Oxidative stress

关键词： Inflammatory signaling | oxidative stress signaling | immune signaling | myocardial cell injury | elderly

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： the TLR4/NF-kappa B signaling pathway, and | inhibition of this pathway reverses the catabolic effects | Osteoarthritis (OA) is a common degenerative | bone and joint disease with an unclear pathogenesis | . Our study identified that the histone

关键词： Osteoarthritis | Histone acetyl transferase | Kat7 | TLR4/NF-kappa B signaling pathway | Cartilage metabolism

摘要： the TLR4/NF-kappa B signaling pathway. This study | model. The expression of TLR4/NF-kappa B signaling | of TLR4, NF-kappa B/P65, and p-P65, reduced the | transcription, thereby suppressing the TLR4/NF-kappa B | signaling pathway. We can conclude that hUCMSC-ex

关键词： Intracerebral hemorrhage | Human umbilical cord mesenchymal stem cells | Exosomes | Inflammation | TLR4/NF-kappa B

摘要：, as well as the TLR4-NF kappa B signaling pathway | inflammatory cytokines. TLR4-NF kappa B signaling pathway | gene expression and TLR4-NF kappa B pathway. Flow | ENG and TLR4. Conclusion: ENG has been proven to | , especially TLR4, may be the target of ENG. These data offer

关键词： Engeletin | CD-Like colitis | Macrophages | M1 polarization | NF-kappa B signaling

摘要： receptor 4/nuclear factor-kappa B (TLR4/NF-kappa B | -induced UC through the inhibition of the TLR4/NF-kappa B | ) signaling pathway and to alleviate oxidative stress | signaling pathway, regulation of the Keap1/Nrf2 pathway | (Keap1/Nrf2) pathway. Notably, EPS failed to exert

关键词： ulcerative colitis | Epimedium polysaccharides | TLR4/NF-kappa B | oxidative stress | autophagy | TLR4/NF‐κB

摘要： TLR4/NF-kappa B signaling and diminished antioxidants | , suppression of TLR4/NF kappa B signaling, and inhibition of | , and IL-6) and suppression of the TLR4/NF-kappa B | signaling pathway. FAR inhibited testicular apoptosis by | Cadmium (Cd) is a highly toxic heavy metal

关键词： Farnesol | Cadmium | Testis | Oxidative stress | Inflammation

摘要： TLR4/MyD88/NF-kappa B signaling cascade pathways | kappa B (NF-kappa B), and myeloid differentiation | celastrol significantly reduced TLR4, MyD88, and NF-kappa | relative toll-like receptor 4 (TLR4), nuclear factor | B expressions, and the levels of inflammatory

关键词： celastrol | diabetic testicular dysfunction | TLR4/MYD88/NF-kappa B signaling pathway

摘要：-alcoholic liver injury effect via the TLR4/NF-kappa B | signaling pathway. | To explore potential protective effects of | natural products against alcohol-induced liver disease | , a bioactivitydriven approach and HSQC-based

关键词： Phenolics constituents | Targeted isolation | Alcohol liver injury | Network pharmacology

摘要： regulated the TLR4/nuclear factor NF-kappaB (NF-kappa B | pancreatic cells at least in part via the TLR4/NF-kappa B | signaling pathway by functioning as a ceRNA for miR-579-3p. | (miR)-579-3p, and toll-like receptor 4 (TLR4) were | -3p and circ_0029407 or TLR4. Our results indicated

关键词： Acute pancreatitis (AP) | circ_0029407 | miR-579-3p | ceRNA | TLR4/NF-kappa B signaling

摘要： TLR4-NF-kappa B signaling pathway. | /Nrf2 and TLR4-NF-kappa B signaling pathways. Material | (NF-kappa B), transforming growth factor (TGF-beta | -gamma, IL-6, IL-1 beta, IL-8, TNF-alpha, NF-kappa B | nitric oxide synthetase (iNOS), nuclear factor kappa B

关键词： Columbianadin | Ulcerative colitis | Apoptosis | Inflammation | Oxidative stress

摘要：-inflammatory response (TNF-alpha/NF-kappa B signaling pathway | mutual activation of TNF-alpha/NF-kappa B, TLR2/TLR4 | receptor 4 (TLR4), nuclear factor kappa B (NF-kappa B | , MDA, TLR2, TLR4, NF-kappa B, TNF-alpha, and hs-cTnT | , MDA, TLR2, TLR4, NF-kappa B, and TNF-alpha predicted

关键词： Inflammatory signaling | oxidative stress signaling | immune signaling | myocardial cell injury | elderly

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： the TLR4/NF-kappa* B signaling pathway, and | inhibition of this pathway reverses the catabolic effects* | Osteoarthritis (OA) is a common degenerative | bone and joint disease with an unclear pathogenesis | . Our study identified that the histone

摘要： the TLR4/NF-kappa* B signaling pathway. This study | model. The expression of TLR4/NF-kappa B signaling | of TLR4, NF-kappa B/P65, and p-P65, reduced the* | transcription, thereby suppressing the TLR4/NF-kappa* B* | signaling pathway. We can conclude that hUCMSC-ex

摘要：, as well as the TLR4-NF kappa B signaling pathway | inflammatory cytokines. TLR4-NF kappa B signaling pathway | gene expression and TLR4-NF kappa* B pathway. Flow* | ENG and TLR4. Conclusion: ENG has been proven to | , especially TLR4, may be the target of ENG. These data offer

摘要： receptor 4/nuclear factor-kappa* B (TLR4/NF-kappa B* | -induced UC through the inhibition of the TLR4/NF-kappa* B* | ) signaling* pathway and to alleviate oxidative stress* | signaling pathway, regulation of the Keap1/Nrf2 pathway | (Keap1/Nrf2) pathway. Notably, EPS failed to exert

摘要： TLR4/NF-kappa B signaling and diminished antioxidants | , suppression of TLR4/NF kappa* B signaling, and inhibition of* | , and IL-6) and suppression of the TLR4/NF-kappa* B* | signaling pathway. FAR inhibited testicular apoptosis by | Cadmium (Cd) is a highly toxic heavy metal

摘要：-alcoholic liver injury effect via the TLR4/NF-kappa* B* | signaling pathway. | To explore potential protective effects of | natural products against alcohol-induced liver disease | , a bioactivitydriven approach and HSQC-based

摘要： regulated the TLR4/nuclear factor NF-kappaB (NF-kappa* B* | pancreatic cells at least in part via the TLR4/NF-kappa* B* | signaling pathway by functioning as a ceRNA for miR-579-3p. | (miR)-579-3p, and toll-like receptor 4 (TLR4) were | -3p and circ_0029407 or TLR4. Our results indicated

摘要： TLR4-NF-kappa B signaling pathway. | /Nrf2 and TLR4-NF-kappa B signaling pathways. Material | (NF-kappa* B), transforming growth factor (TGF-beta* | -gamma, IL-6, IL-1 beta, IL-8, TNF-alpha, NF-kappa* B* | nitric oxide synthetase (iNOS), nuclear factor kappa* B*