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1. Comprehensive approach to in silico identification and in vitro validation of anti-filarial hit molecules targeting the dimer interface of thioredoxin peroxidase 1 in Wuchereria bancrofti : a progress in anti-filariasis drug development NSTL国家科技图书文献中心

Sureshan, Muthusamy |  Rajamanikandan, Sund...... -  《Molecular diversity》 - 2025,29(2) - 1393~1413 - 共21页

摘要:, Wuchereria bancrofti, prevalent in tropical and subtropical | Lymphatic filariasis (LF) remains a |  significant health challenge for populations in developing |  countries. LF is a parasitic disease transmitted by |  mosquitoes, mainly caused by the filarial nematode
关键词: Wuchereria bancrofti |  WbTPx1 |  Molecular docking |  MTT

2. Analysis of Possible Coexistence of Microsporidia, Plasmodium falciparum and Wuchereria bancrofti in Anopheles gambiae s.l within Ahmadu Bello University, Zaria, Nigeria NSTL国家科技图书文献中心

Aliyu, Mukhtar |  Salman, Abdulmalik A...... -  《Acta parasitologica》 - 2025,70(1) - 共6页

摘要: Plasmodium falciparum and Wuchereria bancrofti |  coinfection with W. bancrofti and P. falciparum in An | . falciparum or W. bancrofti. Only 4.03% of the An. gambiae |  and W. bancrofti while no mosquito harboured all the | PurposeAnopheles gambiae is a vector of
关键词: Microsporidia |  Coinfection |  Plasmodium falciparum |  And Anopheles gambiae

3. A morphological identification key to the mosquito disease vectors of the Pacific NSTL国家科技图书文献中心

Gyawali, Narayan |  Russell, Tanya L.... -  《Austral Entomology》 - 2025,64(1) - 共30页

摘要: Wuchereria bancrofti) in the Pacific Islands, countries and | An identification guide is provided for female |  adults of the mosquito groups, complexes or species |  that can be morphologically differentiated and that |  are likely to transmit arboviruses (e.g., dengue
关键词: Aedes |  Anopheles |  Culex |  identification |  morphology |  mosquitoes |  Pacific Islands |  taxonomy

4. SUSCEPTIBILITY STATUS OF Culex quinquefasciafus (DIPTERA: CULICIDAE) AGAINST VARIOUS ADULTICIDES AND LARVICIDES IN UDAIPUR DISTRICT OF SOUTHERN RAJASTHAN, INDIA NSTL国家科技图书文献中心

ASHOK KUMAR |  ARTI PRASAD -  《Pestology》 - 2025,49(1) - 31~39 - 共9页

摘要: Wuchereria bancrofti that causes lymphatic filariasis. In | Mosquito-borne diseases in addition to having |  negative impact in the human health, hampers the socio | -economic status of the affected people in a high rate and |  India being a developing country faces problems in
关键词: Culex quinquefasciatus |  Insecticides |  Susceptible |  DDT |  Bendicarb |  Malathion, Deltamethrin |  Temephos.

5. In silico exploration and in vitro validation of the filarial thioredoxin reductase inhibitory activity of Scytonemin and its derivatives NSTL国家科技图书文献中心

Sen, Animesh |  Dewaker, Varun... -  《Journal of Biomolecular Structure and Dynamics》 - 2025,43(2) - 890~902 - 共13页

摘要: borne parasitic nematode Wuchereria bancrofti is of | Lymphatic filariasis (LF) caused by the vector |  major concern of the World Health Organization (WHO | ). Lack of potential drug candidates worsens the |  situation. Presently available drugs are promising in
关键词: Lymphatic filariasis |  thioredoxin reductase |  Scytonemin |  molecular docking |  MD simulation |  in-vitro enzyme inhibition |  anti-filarial activity

6. Morphological Characterization of Culex Quinquefasciatus (Diptera: Culicidae) Pupae in the Eastern Province of Saudi Arabia NSTL国家科技图书文献中心

Yamany, Abeer S. |  Abdel-Gaber, Rewaida -  《Microscopy research and technique》 - 2025,88(2) - 478~488 - 共11页

摘要: worms. The parasitic worms Wuchereria bancrofti and | Over the last 30 years, several mosquito-borne |  diseases have spread worldwide, threatening human and |  animal health, including lymphatic filariasis | . Lymphatic filariasis is a major public health issue in
关键词: chaetotaxy |  Culex quinquefasciatus |  Culicidae |  morphology |  pupae

7. Immunomodulation of streptozotocin induced Type 1 diabetes mellitus in mouse model by Macrophage migration inhibitory factor-2 (MIF-2) homologue of human lymphatic filarial parasite, Wuchereria bancrofti NSTL国家科技图书文献中心

Singh I. |  Hoti S.L.... -  《Acta tropica.》 - 2024,252 - 107142~107142 - 共6页

摘要:, Wuchereria bancrofti (Wba-MIF2), in the immunomodulation of | ? 2024 Elsevier B.V.Helminth parasites |  modulate the host immune system to ensure a long-lasting |  asymptomatic form of infection generally, mediated by the |  secretion of immunomodulatory molecules and one such
关键词: Immunomodulation |  Lymphatic filariasis |  MIF2 |  Type 1 diabetes |  Wuchereria bancrofti

8. Unpacking Immune Modulation as a Site of Therapeutics Innovation for Nematode Parasite Wuchereria bancrofti : A Temporal Quantitative Phosphoproteomics Profiling of Macrophage Migration Inhibitory Factor 2 NSTL国家科技图书文献中心

Singh, Ishwar |  Kanichery, Anagha... -  《OMICS: A journal of integrative biology》 - 2024,28(3) - 125~137 - 共13页

摘要: and economic impacts. Wuchereria bancrofti is a |  parasite W. bancrofti also produces two homologs of MIF |  research for W. bancrofti. | Nematode infections are common in both humans |  and livestock, with major adverse planetary health
关键词: Wuchereria bancrofti |  filariasis |  planetary health |  proteomics |  spliceosome |  macrophage migration inhibitory factor |  HELMINTH INFECTIONS |  SECRETORY PRODUCTS |  BRUGIA-MALAYI |  IDENTIFICATION...

9. Discovery of potent inhibitors targeting Glutathione S-transferase of Wuchereria bancrofti: a step toward the development of effective anti-filariasis drugs NSTL国家科技图书文献中心

Sureshan Muthusamy |  Prabhu Dhamodharan... -  《Molecular diversity》 - 2024,28(2) - 765~785 - 共21页 - 被引量:2

摘要: major nematodes namely Wuchereria bancrofti, Brugia |  nematode W. bancrofti. Approved drugs were available for |  Glutathione S-transferase (GST) of W. bancrofti, the key | Abstract Lymphatic filariasis (LF) is one of |  the major health problems for the human kind in
关键词: Lymphatic filariasis |  W. bancrofti |  WbGST |  MD simulation |  DFT |  PCA

10. The long and winding road towards new treatments against lymphatic filariasis and onchocerciasis NSTL国家科技图书文献中心

Risch, Frederic |  Kazakov, Alexander... -  《Trends In Parasitology》 - 2024,40(9) - 829~845 - 共17页

摘要:Although lymphatic filariasis and |  onchocerciasis have been targeted for global elimination, these |  helminth infections are still a major public health |  problem across the tropics and subtropics. Despite |  decades of research, treatment options remain limited
关键词: SINGLE-DOSE DIETHYLCARBAMAZINE |  WUCHERERIA-BANCROFTI INFECTION |  WOLBACHIA |  IVERMECTIN |  EFFICACY |  DOXYCYCLINE |  ALBENDAZOLE |  IMPACT |  TRIAL |  PHARMACOKINETICS
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