NSTL国家科技图书文献中心

1. Perturbation of de novo lipogenesis hinders MERS-CoV assembly and release, but not the biogenesis of viral replication organelles NSTL国家科技图书文献中心

Soultsioti, M. | de Jong, A. W. M.... - 《Journal of Virology》 - 2025,99(3) - e02282-24～e02282-24 - 共23页

摘要： generate viral replication* organelles and exploit host* | viral replication* organelles remained unaffected* | replication organelles. Furthermore, our study highlights | pathways and resources to support their replication. They | replication cycle. However, in spite of this general

关键词： coronavirus | TOFA | 2-BP | acetyl-CoA carboxylase | lipid metabolism | palmitoylation

2. The Japanese encephalitis virus NS1 protein concentrates ER membranes in a cytoskeleton-independent manner to facilitate viral replication NSTL国家科技图书文献中心

Xie, Shengda | Lin, Xinxin ... - 《Journal of Virology》 - 2025,99(3) - e02113-24～e02113-24 - 共21页

摘要： reticulum (ER) network to construct replication organelles | main replication* organelles within this membrane* | (ROs) for RNA replication. In this study, we | for viral replication. Subsequently, the virus forms | -concen trated area to facilitate efficient replication

关键词： Japanese encephalitis virus | NS1 | main replication organelles | ER membranes | concentration | viral replication

3. Dengue and Zika virus NS4B proteins differ in topology and in determinants of ER membrane protein complex dependency NSTL国家科技图书文献中心

Porter, Samuel S. | Gilchrist, Talon M.... - 《Journal of Virology》 - 2025,99(2) - e01443-24～e01443-24 - 共14页 - 被引量：1

摘要： structures called replication* organelles (ROs), which are* | replication and other viral activities take place in | Flaviviruses utilize the cellular endoplasmic | reticulum (ER) for all aspects of their lifecycle. Genome | invaginations induced in the ER membrane. Among the required

关键词： virology | flavivirus | Dengue fever | Zika

4. Two Birds With One Stone: RNA Virus Strategies to Manipulate G3BP1 and Other Stress Granule Components NSTL国家科技图书文献中心

Firdaus, Moh Egy Rah... | Dukhno, Eliana ... - 《Wiley Interdisciplinary Reviews.RNA》 - 2025,16(2) - 共22页

摘要： organelles forming in the cytoplasm in response to various | facilitating viral replication, or an antiviral role, by | incorporate them into viral replication* sites. G3BP1 is a* | Stress granules (SGs) are membrane-less | types of stress, including viral infection. SGs and SG

关键词： G3BP1 | RNA viruses | stress granules | viral proteins

5. Cellular mechanisms of acute rhabdomyolysis in inherited metabolic diseases NSTL国家科技图书文献中心

de Calbiac, Hortense | Imbard, Apolline ... - 《Journal of inherited metabolic disease》 - 2025,48(1) - e12781～e12781 - 共28页 - 被引量：1

摘要： organelles. Consequently, a genetic defect involving ATP | viral replication. In response, infections, recognized | Acute rhabdomyolysis (RM) constitutes a life | -threatening emergency resulting from the (acute) breakdown | of skeletal myofibers, characterized by a plasma

关键词： anterograde trafficking | ATP | autophagy | calcium | cellular trafficking | complex lipid membrane composition | inherited metabolic diseases | mitophagy | rhabdomyolysis

6. Rabies Virus Phosphoprotein Exhibits Thermoresponsive Phase Separation with a Lower Critical Solution Temperature NSTL国家科技图书文献中心

Bouchama, Fella | Mubashira, Khadeeja ... - 《Journal of Molecular Biology》 - 2025,437(2) - 共25页

摘要： liquid organelles* (Negri bodies) in the cytoplasm of* | replication and nucleocapsid assembly take place, but the | Rabies virus (RABV) generates membrane-less | its host cell, where genome transcription and | mechanisms of their assembly and maturation remain to be

关键词： biological condensate | LCST | LLPS | membrane-less compartment | rabies virus

7. Analysis of the Functional Role of TIMM29 in the Hepatitis B Virus Life Cycle NSTL国家科技图书文献中心

Abueldahab, Limia | Suwanmanee, Yadarat ... - 《Microbiology and Immunology》 - 2025,69(4) - 229～246 - 共18页

摘要： various cell organelles* and proteins that ensure* | and replication* were downregulated in cells stably* | Hepatitis B virus (HBV) causes chronic | hepatitis B, which can progress to liver cirrhosis and | hepatocellular carcinoma. HBV has complex interactions with

关键词： ARRDC3 | BASP1 | hepatitis B virus (HBV) | mitochondria | preS1 | TIMM29

8. Electron microscopy: The key to resolve RNA viruses replication organelles NSTL国家科技图书文献中心

Debora Stelitano | Mirko Cortese - 《Molecular Microbiology》 - 2024,121(4) - 679～687 - 共9页 - 被引量：1

摘要： generate viral replication* organelles that form a* | knowledge of replication* organelles biogenesis, structure* | cofactors accumulate to assure an efficient replication* of* | Abstract Positive‐sense single‐stranded RNA | viruses significantly reshape intracellular membranes to

关键词： Cryo‐EM | electron microscopy | RNA viruses | viral pores | viral replication organelles

9. In situ fate of Chikungunya virus replication organelles NSTL国家科技图书文献中心

Justine Girard | Olivier Le Bihan ... - 《Journal of Virology》 - 2024,98(7) - 1～6 - 共6页

摘要： occurs in specialized membranous replication organelles | in humans. Replication* of the viral RNA genome* | replication complex. Initially generated by RNA synthesis | ROs and associated replication* machinery in infected* | resolved replication* complex. The unexpectedly*

关键词： alphavirus | Chikungunya | replication organelles | nsP1 | cryogenic-electron microscopy | sub-tomogram averaging | electron tomography | CEMOVIS

10. Positive-strand RNA virus replication organelles at a glance NSTL国家科技图书文献中心

Stancheva, Viktoriya... | Sanyal, Sumana - 《Journal of Cell Science》 - 2024,137(17) - jcs262164～jcs262164 - 共6页

摘要：Membrane-bound replication* organelles (ROs* | alterations of various host organelles, provide a protective | niche for viral genome replication. Some ROs are | ) are a unifying feature among diverse positive-strand | RNA viruses. These compartments, formed as

关键词： RNA virus | Replication organelles | Virus-host interaction | OXYSTEROL-BINDING PROTEIN | DENGUE VIRUS | ENDOPLASMIC-RETICULUM | WEST NILE | MEMBRANOUS REPLICATION | POLIOVIRUS INFECTION | VIRAL REPLICATION...

摘要： generate viral replication organelles and exploit host | viral replication organelles remained unaffected | replication organelles. Furthermore, our study highlights | pathways and resources to support their replication. They | replication cycle. However, in spite of this general

关键词： coronavirus | TOFA | 2-BP | acetyl-CoA carboxylase | lipid metabolism | palmitoylation

摘要： reticulum (ER) network to construct replication organelles | main replication organelles within this membrane | (ROs) for RNA replication. In this study, we | for viral replication. Subsequently, the virus forms | -concen trated area to facilitate efficient replication

关键词： Japanese encephalitis virus | NS1 | main replication organelles | ER membranes | concentration | viral replication

摘要： structures called replication organelles (ROs), which are | replication and other viral activities take place in | Flaviviruses utilize the cellular endoplasmic | reticulum (ER) for all aspects of their lifecycle. Genome | invaginations induced in the ER membrane. Among the required

关键词： virology | flavivirus | Dengue fever | Zika

摘要： organelles forming in the cytoplasm in response to various | facilitating viral replication, or an antiviral role, by | incorporate them into viral replication sites. G3BP1 is a | Stress granules (SGs) are membrane-less | types of stress, including viral infection. SGs and SG