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1. Integrating single nuclei and bulk RNA sequencing in rice shoot apical meristems uncovers candidate early floral transition gene networks NSTL国家科技图书文献中心

Traversa, Daniele |  Vicentini, Giulio... -  《Plant Reproduction》 - 2025,38(1) - 共4页

摘要: resolved single nuclei RNA-seq with bulk RNA-seq |  bulk RNA-seq with single nuclei RNA-seq analysis to |  conceptual differences between single nuclei RNA-seq and | Key messageWe describe transcriptional |  dynamics at the rice shoot apex by integrating time
关键词: Floral transition |  Rice |  Shoot apex |  Single nuclei transcriptomics

2. Single-nuclei RNA-sequencing fails to detect molecular dysregulation in the preeclamptic placenta NSTL国家科技图书文献中心

Admati, Inbal |  Skarbianskis, Niv... -  《Placenta》 - 2025,159 - 170~179 - 共10页

摘要: single-nuclei RNA-seq may be preferable in the placenta |  single-cell and single-nuclei RNA-seq. The datasets |  by single-nuclei RNA-seq (snRNA-seq), restricting | Introduction: Single-cell RNA-seq (scRNA |  inaccessible to cell dissociation. Nuclei isolation and
关键词: Single-cell RNA-seq |  Single-nuclei RNA-seq |  Preeclampsia |  Cell type detection |  Syncytiotrophoblast |  Immune cells

3. Thalamus of Reptiles and Mammals: Some Significant Differences NSTL国家科技图书文献中心

Pritz, Michael B. -  《Brain, behavior and evolution》 - 2025,100(1) - 49~57 - 共9页

摘要: dorsal thalamic nuclei lack local circuit neurons | , whereas these same nuclei in mammals contain varying |  with two separate nuclei each being associated with a |  reticular nucleus, which is a single structure, are |  homogeneous. Key messages: Transcriptomics and development
关键词: Cerebral cortex |  Dorsal thalamus |  Dorsal ventricular ridge |  Forebrain circuitry |  Pallium |  Ventral thalamus

4. Senescent Syncytiotrophoblast Secretion During Early Onset Preeclampsia NSTL国家科技图书文献中心

Olivia Nonn |  Olivia Debnath... -  《Hypertension》 - 2025,82(5) - 787~799 - 共13页

摘要: preeclampsia and healthy controls using single-nucleus RNA |  sequencing combined with spatial transcriptomics. The |  nuclei with patterns of dysregulation associated with a |  1) and activin A, as identified in our single | BACKGROUND: Preeclampsia is a severe
关键词: placenta, plasminogen activator inhibitor 1, pre-eclampsia, pregnancy, pregnancy trimesters

5. Single nuclei transcriptomics in diabetic mice reveals altered brain hippocampal endothelial cell function, permeability, and behavior NSTL国家科技图书文献中心

Nuthikattu, Saivagee... |  Milenkovic, Dragan... -  《Biochimica et biophysica acta. Molecular basis of disease: BBA》 - 2024,1870(2) - 166970~166970 - 共6页

摘要: comprehensive, multilevel, integrated, single nuclei |  in dementia has yet to be defined. We used single |  nuclei RNA sequencing technology to profile the |  transcriptomics support the hypothesis of T2DM-mediated neuro | Type 2 diabetes mellitus (T2DM) is a metabolic
关键词: Type 2 diabetes mellitus |  Dementia |  Blood brain barrier |  Cognition |  Endothelial cells |  hippocampus |  PROTEIN-KINASE-C |  NEUROVASCULAR DYSFUNCTION |  MICROVASCULAR DYSFUNCTION |  ALZHEIMERS-DISEASE...

6. Obesity and the cerebral cortex: Underlying neurobiology in mice and humans NSTL国家科技图书文献中心

Patel Y. |  Woo A.... -  《Brain, Behavior, and Immunity》 - 2024,119 - 637~647 - 共11页

摘要: volume in humans. Single-nuclei transcriptomics of the |  single-nuclei cortical transcriptomics in a mouse model |  single-nucleus transcriptomic data from the human | ? 2024Obesity is a major modifiable risk |  factor for Alzheimer's disease (AD), characterized by
关键词: Bioinformatics |  Cerebral cortex |  In silico transcriptomics |  Magnetic resonance imaging |  Obesity |  Serial 2-photon tomography |  Single cell RNA sequencing

7. Protein N -glycans in Healthy and Sclerotic Glomeruli in Diabetic Kidney Disease NSTL国家科技图书文献中心

Velickovic, Dusan |  Shapiro, John P.... -  《Journal of the American Society of Nephrology: JASN》 - 2024,35(9) - 1198~1207 - 共10页

摘要: analysis of single nuclei transcriptomics (snRNAseq) data |  transcriptomics revealed protein N-glycosylation characteristic | Background Diabetes is expected to directly |  impact renal glycosylation, yet to date, there has not |  been a comprehensive evaluation of alterations in N
关键词: GLYCOSYLATION |  SIALYLATION

8. Novel single‐nucleus transcriptomics unravels developmental and functionally controlled principles of mammalian neuromuscular junctions NSTL国家科技图书文献中心

Hermona Soreq -  《Journal of neurochemistry.》 - 2024,168(4) - 339~341 - 共3页

摘要: junctions (NMJs) using single‐nucleus transcriptomics |  characteristics. Unlike other single‐nucleus transcriptomics |  of individually studied nuclei and their functional |  studies, which tend to be limited to single |  studied nuclei emerged as essential for NMJ neurogenesis
关键词: Editorial Highlight

9. Spatial genomics: mapping human steatotic liver disease NSTL国家科技图书文献中心

Matchett, Kylie P. |  Paris, Jasmin... -  《Nature reviews. Gastroenterology & hepatology》 - 2024,21(9) - 646~660 - 共15页

摘要: single-cell and single-nuclei RNA sequencing have |  this single-cell information in its native spatial |  identification.This Perspective discusses single-cell and single | -nuclei RNA sequencing in metabolic dysfunction |  following the advances in spatial transcriptomics.
关键词: NONALCOHOLIC FATTY LIVER |  SINGLE-CELL |  TRANSCRIPTOMICS REVEALS |  GENE-EXPRESSION |  T-CELLS |  TISSUE |  NASH |  COMMUNICATION |  PROGRESSION |  MECHANISMS

10. Decoding the muscle transcriptome of patients with late-onset Pompe disease reveals markers of disease progression NSTL国家科技图书文献中心

Monceau, Alexandra |  Nath, Rasya Gokul... -  《Brain》 - 2024,147(12) - 4213~4226 - 共14页

摘要: single nuclei RNA sequencing and spatial |  among nuclei within the multinucleated skeletal muscle |  single-nucleus RNA sequencing to uncover changes in the |  transcriptomics to compare the transcriptome of control |  of single-nucleus RNA sequencing and spatial
关键词: glycogen storage disease |  mitochondria abnormality |  metabolism
检索条件Single nuclei transcriptomics
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