NSTL国家科技图书文献中心

1. Integrating single nuclei and bulk RNA sequencing in rice shoot apical meristems uncovers candidate early floral transition gene networks NSTL国家科技图书文献中心

Traversa, Daniele | Vicentini, Giulio ... - 《Plant Reproduction》 - 2025,38(1) - 共4页

摘要： resolved single* nuclei RNA-seq with bulk RNA-seq* | bulk RNA-seq with single* nuclei RNA-seq analysis to* | conceptual differences between single* nuclei RNA-seq and* | Key messageWe describe transcriptional | dynamics at the rice shoot apex by integrating time

关键词： Floral transition | Rice | Shoot apex | Single nuclei transcriptomics

2. Hypothesizing glucagon-like peptide 1 (GLP-1), agonists promote hypodopaminergia, resulting in heightened addictive reward-seeking and altered mood: Breaking the bubble and adding salt to a wound NSTL国家科技图书文献中心

Blum, Kenneth | Dennen, Catherine A.... - 《Medical hypotheses》 - 2025,198 - 111612～111612 - 共12页

摘要： decreases insulin secretion. Single-nuclei transcriptomics | Recent articles have suggested that the | agonistic effects of GLP-1 in alcohol use disorder and | substance use disorder are mediated centrally, partly | through the downregulation of dopamine signaling. This

关键词： Glucagon-Like Peptide 1 (GLP-1) | Addiction | Substance Use Disorder (SUD) | Suicidality | Metabolic Syndrome | Epigenetics | Genetics | Reward Deficiency Syndrome (RDS) | Dopaminergic Dysregulation | Genetic Addiction Risk Severity (GARS)

3. Single-nuclei RNA-sequencing fails to detect molecular dysregulation in the preeclamptic placenta NSTL国家科技图书文献中心

Admati, Inbal | Skarbianskis, Niv ... - 《Placenta》 - 2025,159 - 170～179 - 共10页

摘要： single-nuclei RNA-seq may be preferable in the placenta | single-cell and single-nuclei RNA-seq. The datasets | by single-nuclei* RNA-seq (snRNA-seq), restricting* | Introduction: Single-cell RNA-seq (scRNA | inaccessible to cell dissociation. Nuclei* isolation and*

关键词： Single-cell RNA-seq | Single-nuclei RNA-seq | Preeclampsia | Cell type detection | Syncytiotrophoblast | Immune cells

4. Thalamus of Reptiles and Mammals: Some Significant Differences NSTL国家科技图书文献中心

Pritz, Michael B. - 《Brain, behavior and evolution》 - 2025,100(1) - 49～57 - 共9页

摘要： dorsal thalamic nuclei* lack local circuit neurons* | , whereas these same nuclei* in mammals contain varying* | with two separate nuclei* each being associated with a* | reticular nucleus, which is a single* structure, are* | homogeneous. Key messages: Transcriptomics* and development*

关键词： Cerebral cortex | Dorsal thalamus | Dorsal ventricular ridge | Forebrain circuitry | Pallium | Ventral thalamus

5. Senescent Syncytiotrophoblast Secretion During Early Onset Preeclampsia NSTL国家科技图书文献中心

Olivia Nonn | Olivia Debnath ... - 《Hypertension》 - 2025,82(5) - 787～799 - 共13页

摘要： preeclampsia and healthy controls using single-nucleus RNA | sequencing combined with spatial transcriptomics. The | nuclei with patterns of dysregulation associated with a | 1) and activin A, as identified in our single | BACKGROUND: Preeclampsia is a severe

关键词： placenta, plasminogen activator inhibitor 1, pre-eclampsia, pregnancy, pregnancy trimesters

6. Single nuclei transcriptomics in diabetic mice reveals altered brain hippocampal endothelial cell function, permeability, and behavior NSTL国家科技图书文献中心

Nuthikattu, Saivagee... | Milenkovic, Dragan ... - 《Biochimica et biophysica acta. Molecular basis of disease: BBA》 - 2024,1870(2) - 166970～166970 - 共6页

摘要： comprehensive, multilevel, integrated, single nuclei | in dementia has yet to be defined. We used single | nuclei RNA sequencing technology to profile the | transcriptomics support the hypothesis of T2DM-mediated neuro | Type 2 diabetes mellitus (T2DM) is a metabolic

关键词： Type 2 diabetes mellitus | Dementia | Blood brain barrier | Cognition | Endothelial cells | hippocampus | PROTEIN-KINASE-C | NEUROVASCULAR DYSFUNCTION | MICROVASCULAR DYSFUNCTION | ALZHEIMERS-DISEASE...

7. Obesity and the cerebral cortex: Underlying neurobiology in mice and humans NSTL国家科技图书文献中心

Patel Y. | Woo A.... - 《Brain, Behavior, and Immunity》 - 2024,119 - 637～647 - 共11页

摘要： volume in humans. Single-nuclei* transcriptomics of the* | single-nuclei cortical transcriptomics in a mouse model | single-nucleus transcriptomic data from the human | ? 2024Obesity is a major modifiable risk | factor for Alzheimer's disease (AD), characterized by

关键词： Bioinformatics | Cerebral cortex | In silico transcriptomics | Magnetic resonance imaging | Obesity | Serial 2-photon tomography | Single cell RNA sequencing

8. Protein N -glycans in Healthy and Sclerotic Glomeruli in Diabetic Kidney Disease NSTL国家科技图书文献中心

Velickovic, Dusan | Shapiro, John P.... - 《Journal of the American Society of Nephrology: JASN》 - 2024,35(9) - 1198～1207 - 共10页

摘要： analysis of single* nuclei transcriptomics (snRNAseq) data* | transcriptomics revealed protein N-glycosylation characteristic | Background Diabetes is expected to directly | impact renal glycosylation, yet to date, there has not | been a comprehensive evaluation of alterations in N

关键词： GLYCOSYLATION | SIALYLATION

9. Novel single‐nucleus transcriptomics unravels developmental and functionally controlled principles of mammalian neuromuscular junctions NSTL国家科技图书文献中心

Hermona Soreq - 《Journal of neurochemistry.》 - 2024,168(4) - 339～341 - 共3页

摘要： junctions (NMJs) using single‐nucleus transcriptomics | characteristics. Unlike other single‐nucleus transcriptomics | of individually studied nuclei* and their functional* | studies, which tend to be limited to single | studied nuclei* emerged as essential for NMJ neurogenesis*

关键词： Editorial Highlight

10. Spatial genomics: mapping human steatotic liver disease NSTL国家科技图书文献中心

Matchett, Kylie P. | Paris, Jasmin ... - 《Nature reviews. Gastroenterology & hepatology》 - 2024,21(9) - 646～660 - 共15页

摘要： single-cell and single-nuclei RNA sequencing have | this single-cell information in its native spatial | identification.This Perspective discusses single-cell and single | -nuclei* RNA sequencing in metabolic dysfunction* | following the advances in spatial transcriptomics.

关键词： NONALCOHOLIC FATTY LIVER | SINGLE-CELL | TRANSCRIPTOMICS REVEALS | GENE-EXPRESSION | T-CELLS | TISSUE | NASH | COMMUNICATION | PROGRESSION | MECHANISMS

摘要： resolved single nuclei RNA-seq with bulk RNA-seq | bulk RNA-seq with single nuclei RNA-seq analysis to | conceptual differences between single nuclei RNA-seq and | Key messageWe describe transcriptional | dynamics at the rice shoot apex by integrating time

关键词： Floral transition | Rice | Shoot apex | Single nuclei transcriptomics

摘要： decreases insulin secretion. Single-nuclei transcriptomics | Recent articles have suggested that the | agonistic effects of GLP-1 in alcohol use disorder and | substance use disorder are mediated centrally, partly | through the downregulation of dopamine signaling. This

关键词： Glucagon-Like Peptide 1 (GLP-1) | Addiction | Substance Use Disorder (SUD) | Suicidality | Metabolic Syndrome | Epigenetics | Genetics | Reward Deficiency Syndrome (RDS) | Dopaminergic Dysregulation | Genetic Addiction Risk Severity (GARS)

摘要： single-nuclei RNA-seq may be preferable in the placenta | single-cell and single-nuclei RNA-seq. The datasets | by single-nuclei RNA-seq (snRNA-seq), restricting | Introduction: Single-cell RNA-seq (scRNA | inaccessible to cell dissociation. Nuclei isolation and

关键词： Single-cell RNA-seq | Single-nuclei RNA-seq | Preeclampsia | Cell type detection | Syncytiotrophoblast | Immune cells

摘要： dorsal thalamic nuclei lack local circuit neurons | , whereas these same nuclei in mammals contain varying | with two separate nuclei each being associated with a | reticular nucleus, which is a single structure, are | homogeneous. Key messages: Transcriptomics and development

关键词： Cerebral cortex | Dorsal thalamus | Dorsal ventricular ridge | Forebrain circuitry | Pallium | Ventral thalamus

摘要： preeclampsia and healthy controls using single-nucleus RNA | sequencing combined with spatial transcriptomics. The | nuclei with patterns of dysregulation associated with a | 1) and activin A, as identified in our single | BACKGROUND: Preeclampsia is a severe

关键词： placenta, plasminogen activator inhibitor 1, pre-eclampsia, pregnancy, pregnancy trimesters

摘要： comprehensive, multilevel, integrated, single nuclei | in dementia has yet to be defined. We used single | nuclei RNA sequencing technology to profile the | transcriptomics support the hypothesis of T2DM-mediated neuro | Type 2 diabetes mellitus (T2DM) is a metabolic

关键词： Type 2 diabetes mellitus | Dementia | Blood brain barrier | Cognition | Endothelial cells | hippocampus | PROTEIN-KINASE-C | NEUROVASCULAR DYSFUNCTION | MICROVASCULAR DYSFUNCTION | ALZHEIMERS-DISEASE...

摘要： volume in humans. Single-nuclei transcriptomics of the | single-nuclei cortical transcriptomics in a mouse model | single-nucleus transcriptomic data from the human | ? 2024Obesity is a major modifiable risk | factor for Alzheimer's disease (AD), characterized by

关键词： Bioinformatics | Cerebral cortex | In silico transcriptomics | Magnetic resonance imaging | Obesity | Serial 2-photon tomography | Single cell RNA sequencing

摘要： analysis of single nuclei transcriptomics (snRNAseq) data | transcriptomics revealed protein N-glycosylation characteristic | Background Diabetes is expected to directly | impact renal glycosylation, yet to date, there has not | been a comprehensive evaluation of alterations in N

关键词： GLYCOSYLATION | SIALYLATION

摘要： junctions (NMJs) using single‐nucleus transcriptomics | characteristics. Unlike other single‐nucleus transcriptomics | of individually studied nuclei and their functional | studies, which tend to be limited to single | studied nuclei emerged as essential for NMJ neurogenesis

关键词： Editorial Highlight

摘要： single-cell and single-nuclei RNA sequencing have | this single-cell information in its native spatial | identification.This Perspective discusses single-cell and single | -nuclei RNA sequencing in metabolic dysfunction | following the advances in spatial transcriptomics.

关键词： NONALCOHOLIC FATTY LIVER | SINGLE-CELL | TRANSCRIPTOMICS REVEALS | GENE-EXPRESSION | T-CELLS | TISSUE | NASH | COMMUNICATION | PROGRESSION | MECHANISMS

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： resolved single* nuclei RNA-seq with bulk RNA-seq* | bulk RNA-seq with single* nuclei RNA-seq analysis to* | conceptual differences between single* nuclei RNA-seq and* | Key messageWe describe transcriptional | dynamics at the rice shoot apex by integrating time

摘要： single-nuclei RNA-seq may be preferable in the placenta | single-cell and single-nuclei RNA-seq. The datasets | by single-nuclei* RNA-seq (snRNA-seq), restricting* | Introduction: Single-cell RNA-seq (scRNA | inaccessible to cell dissociation. Nuclei* isolation and*

摘要： dorsal thalamic nuclei* lack local circuit neurons* | , whereas these same nuclei* in mammals contain varying* | with two separate nuclei* each being associated with a* | reticular nucleus, which is a single* structure, are* | homogeneous. Key messages: Transcriptomics* and development*

摘要： volume in humans. Single-nuclei* transcriptomics of the* | single-nuclei cortical transcriptomics in a mouse model | single-nucleus transcriptomic data from the human | ? 2024Obesity is a major modifiable risk | factor for Alzheimer's disease (AD), characterized by

摘要： analysis of single* nuclei transcriptomics (snRNAseq) data* | transcriptomics revealed protein N-glycosylation characteristic | Background Diabetes is expected to directly | impact renal glycosylation, yet to date, there has not | been a comprehensive evaluation of alterations in N

摘要： junctions (NMJs) using single‐nucleus transcriptomics | characteristics. Unlike other single‐nucleus transcriptomics | of individually studied nuclei* and their functional* | studies, which tend to be limited to single | studied nuclei* emerged as essential for NMJ neurogenesis*

摘要： single-cell and single-nuclei RNA sequencing have | this single-cell information in its native spatial | identification.This Perspective discusses single-cell and single | -nuclei* RNA sequencing in metabolic dysfunction* | following the advances in spatial transcriptomics.