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1. Heterogeneous redox responses in NHDF cells primed to enhance mitochondrial bioenergetics NSTL国家科技图书文献中心

Pinho, Sonia A. |  Oliveira, Paulo J.... -  《Biochimica et biophysica acta.Molecular basis of disease》 - 2025,1871(1) - 167495~167495 - 共20页

摘要: suggests that enhanced mitochondrial bioenergetics |  precision mitochondrial medicine. We investigated how |  metabolic priming, which enhances mitochondrial |  bioenergetics, influences redox responses to oxidative stress |  mitochondrial polarization and a lower percentage of cells in
关键词: Aging |  Mitochondria |  Bioenergetics |  Redox |  Heterogeneity |  NHDF cells

2. Disturbances in mitochondrial bioenergetics and control quality and unbalanced redox homeostasis in the liver of a mouse model of mucopolysaccharidosis type II NSTL国家科技图书文献中心

Pinheiro, Camila Vie... |  Ribeiro, Rafael Teix...... -  《Molecular and Cellular Biochemistry》 - 2025,480(1) - 411~424 - 共14页 - 被引量:1

摘要: evaluated bioenergetics, redox homeostasis, and |  mitochondrial dynamics in the liver of 6-month-old MPS II mice |  malate dehydrogenase. The activity of mitochondrial |  activities were not affected. In contrast, mitochondrial |  proteins involved in mitochondrial mass and dynamics were
关键词: Mucopolysaccharidosis type II |  Mitochondrial bioenergetics |  Mitochondrial dynamics |  Redox homeostasis |  Liver |  MPS II mice

3. Acute CCl 4 -induced intoxication reduces complex I, but not complex II-based mitochondrial bioenergetics - protective role of succinate NSTL国家科技图书文献中心

Ikromova, Fozila R. |  Khasanov, Feruzbek A...... -  《Journal of Bioenergetics and Biomembranes》 - 2025,57(1) - 11~26 - 共16页

摘要: supplementation to improve mitochondrial bioenergetics during |  of mitochondrial membrane potential (Delta Psi(m | )), mitochondrial NAD(P)H pool and NADH redox index, mitochondrial |  functions of the liver. Boosting of mitochondrial |  bioenergetics through the complex II, using succinate as
关键词: Complex I-based respiration |  Succinate |  Mitochondria |  Acute liver failure |  CCl4 intoxication

4. Skeletal muscle hypertrophy and enhanced mitochondrial bioenergetics following electrical stimulation exercises in spinal cord injury: a randomized clinical trial NSTL国家科技图书文献中心

Gorgey, Ashraf S. |  Khalil, Refka E.... -  《European journal of applied physiology》 - 2025,125(4) - 1075~1089 - 共15页

摘要: enhance mitochondrial bioenergetics after SCI. NMES-RT |  training (PMT) and FES-LEC on mitochondrial electron | We examined the combined effects of |  neuromuscular electrical stimulation-resistance training (NMES | -RT) and functional electrical stimulation-lower
关键词: Neuromuscular electrical stimulation |  Functional electrical stimulation |  Resistance training |  Electron transport chain |  Mitochondrial complexes |  Citrate synthase |  Spinal cord injury

5. Altered Mitochondrial Bioenergetics and Calcium Kinetics in Young-Onset PLA2G6 Parkinson's Disease iPSCs NSTL国家科技图书文献中心

Thasneem Musthafa |  Syed Kavish Nizami... -  《Journal of neurochemistry.》 - 2025,169(4) - e70059~e70059 - 共22页

摘要: hyperpolarization of mitochondrial membrane potentials were |  compensation for mitochondrial respiration. Elevated basal | Parkinson's disease (PD) has emerged as a |  multisystem disorder affecting multiple cellular and |  organellar systems in addition to the dopaminergic neurons
关键词: PLA2G6; Parkinson's disease; disease modeling; human iPSC; mitochondrial dysfunction.

6. Mitochondrial bioenergetics stimulates autophagy for pathological MAPT/Tau clearance in tauopathy neurons NSTL国家科技图书文献中心

Jia, Nuo |  Ganesan, Dhasarathan... -  《Autophagy》 - 2025,21(1) - 54~79 - 共26页

摘要: indicated in tauopathy. While mitochondrial bioenergetic |  mitochondrial biosynthesis and supply of |  mitochondrial bioenergetic deficiency in tauopathy-related | ; HsMAPT/Tau, human MAPT; IMM, inner mitochondrial | Hyperphosphorylation and aggregation of MAPT
关键词: Alzheimer |  anaplerotic metabolism |  autophagy |  phospholipid biosynthesis |  phosphorylated MAPT/tau |  tauopathy

7. α-Ketoisocaproic Acid Disrupts Mitochondrial Bioenergetics in the Brain of Neonate Rats: Molecular Modeling Studies of α-ketoglutarate Dehydrogenase Subunits Inhibition NSTL国家科技图书文献中心

Zemniacak, angela Be... |  Ribeiro, Rafael Teix...... -  《Neurochemical research》 - 2025,50(1) - Article: 76~Article: 76 - 共15页

摘要: compromises mitochondrial bioenergetics in the neonatal rat | ), KMV (1 mM), and KIV (1 mM) on mitochondrial |  bioenergetics in the cerebral cortex of neonate (one-day-old |  CCCP) mitochondrial respiration supported by pyruvate | Brain accumulation of the branched-chain alpha
关键词: Maple syrup urine disease |  alpha-Ketoisocaproic acid |  Brain |  Bioenergetics |  Docking simulations

8. Oxidative imbalance linked to impaired mitochondrial bioenergetics mediates the toxicity of mesoionic compounds MI-D and MI-J in hepatocarcinoma cells (HepG2) NSTL国家科技图书文献中心

Neves, Ana Paula Per... |  Kaziuk, Fernando Die...... -  《Free radical research》 - 2025,59(4) - 308~320 - 共13页

摘要:Hepatocellular carcinoma (HCC) is a common and |  deadly form of liver cancer with limited treatment |  options for advanced stages. Mesoionic compounds MI-D |  and MI-J have shown potential for treating HCC due |  to their significant toxicity to these cells. This
关键词: Mesoionic compounds |  oxidative stress |  hepatocellular carcinoma |  antioxidant enzymes |  redox balance

9. Oil mist particulate matter induces myocardial tissue injury by impairing fatty acid metabolism and mitochondrial bioenergetics function via inhibiting the PPAR alpha signaling pathway in rats NSTL国家科技图书文献中心

Liu X. |  Liu H.... -  《Environmental Pollution》 - 2025,365(Jan.) - 1.1~1.13 - 共13页 - 被引量:2

摘要: inflammatory responses, accompanied by mitochondrial |  closely associated with changes in mitochondrial |  metabolism, mitochondrial dysfunction, and cell apoptosis |  metabolism, contributes to mitochondrial damage and | © 2024 Elsevier LtdAir pollution is a
关键词: Fatty acid metabolism |  Mitochondrial dysfunction |  Myocardial tissue injury |  Oil mist particulate matter |  PPAR signaling pathway

10. Unraveling mitochondrial dysfunction: comprehensive perspectives on its impact on neurodegenerative diseases NSTL国家科技图书文献中心

Yusoff, Abdul Aziz M... |  Khair, Siti Zulaikha... -  《Reviews in the neurosciences》 - 2025,36(1) - 53~90 - 共38页

摘要: contributing factors, mitochondrial dysfunction has emerged |  comprehensive overview of how mitochondrial impairment | , alterations in mitochondrial dynamics (such as fusion or |  mitochondrial dysfunction in these diseases. | Neurodegenerative diseases represent a
关键词: mitochondrial bioenergetics and biogenesis |  mitochondrial dynamics and mitophagy |  mitochondrial dysfunctions |  neurodegenerative diseases |  therapy
检索条件Mitochondrial bioenergetics

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