NSTL国家科技图书文献中心

1. Mertk signaling and immune regulation in T cells NSTL国家科技图书文献中心

Varsanyi, Christophe... | Birge, Raymond B. - 《Journal of Leukocyte Biology》 - 2025,117(1) - qiae253～qiae253 - 共3页 - 被引量：1

摘要： myeloid cells, TAM family members, particularly Mertk | study shows that Mertk* expressed on human T cells* | diversification of Mertk* in immune regulation and its* | While widely viewed as inhibitory receptors | that drive efferocytosis and immune resolution on

关键词： cancer | central memory | co-stimulation | Mertk | T cells

2. Ovarian expression of MerTK and its ligand Pros1 in non-pregnant estrus and pregnant mice NSTL国家科技图书文献中心

Kirimlioglu, Esma | Cernomorcenco, Alexa...... - 《Journal of molecular histology》 - 2025,56(1) - Article: 12～Article: 12 - 共11页

摘要：AimThe interaction of MerTK, which negatively | MerTK and Pros1, intensely expressed in macrophages (M | used qPCR to evaluate Mertk* and Pros1 mRNA levels and* | increased in GD15. MerTK* and Pros1 protein levels in mouse* | groups. MerTK* and Pros1 positive M phi s were observed*

关键词： Ovary | Corpus luteum | Macrophage | MerTK | Pros1

3. MerTK signaling in human primary T cells modulates memory potential and improves recall response NSTL国家科技图书文献中心

Rahbech, Anne | Kurzay, Annina ... - 《Journal of Leukocyte Biology》 - 2025,117(3) - qiae226～qiae226 - 共12页 - 被引量：1

摘要： MerTK signaling on activated human primary CD8(+) T | role of MerTK* expression in human CD8(+) T cells. We* | uncover a clear link between MerTK* expression and less* | molecule IFN gamma upon recall responses of MerTK | . Our findings describe a role of MerTK* expression in*

关键词： co-stimulation | immunotherapy | MerTK | TAM receptor

4. MerTK is Ectopically Expressed and Affects the Biological Function in Diffuse Large B-Cell Lymphoma NSTL国家科技图书文献中心

Yan Li | Cunzhen Shi ... - 《Hematological oncology》 - 2025,43(3) - e70089～e70089 - 共13页

摘要： the expression of MerTK* in DLBCL. Targeted knockdown* | of MerTK* by shRNA was conducted in DLBCL cell lines* | to evaluate the effects of MerTK* in vivo. We found* | for the first time that MerTK, a proto-oncogene, is | . Targeted knockdown of MerTK* or application of UNC2025, a*

关键词： ANXA1; MerTK; autophagy; diffuse large B‐cell lymphoma; targeted therapy

5. Development of New N-{4-[(7-Chloro-5-methylpyrrolo[2,1-f] [1,2,4]triazin-4-yl)oxy]-3-fluorophenyl}benzenesulfonamide Analogues: Exploring Anticancer Potential through MerTK Inhibition NSTL国家科技图书文献中心

Balaji Dashrath Sath... | Meenakshi Meenakshi ... - 《Synlett》 - 2025,36(5) - 522～530 - 共9页

摘要： (MerTK), a part of the TAM (TYRO3, AXL, and MerTK | active domain of MerTK* and the structural* | displayed a moderate MerTK* inhibitory potential. Molecular* | -docking studies were performed to corroborate the MerTK | allosteric pocket of MerTK* protein. These promising results*

关键词： cancer chemotherapeutics | pyrrolotriazines | sulfonamides | metabolic studies | kinase inhibitors

6. A single mutation in the PrM gene of Zika virus determines AXL dependency for infection of human neural cells NSTL国家科技图书文献中心

Khasa, Renu | Ogden, Sarah C.... - 《Journal of Virology》 - 2025,99(4) - e0187324～e0187324 - 共16页

摘要： TYRO3 or MerTK, for ZIKV infection. Additionally | Zika virus (ZIKV) is spread by mosquito bites | and is unique among known flaviviruses for being | able to cause microcephaly. Entry factors for ZIKV | are incompletely understood, but phosphatidylserine

关键词： virus-host interactions

7. Black phosphorus nanoplatform coated with platelet membrane improves inhibition of atherosclerosis progression through macrophage targeting and efferocytosis NSTL国家科技图书文献中心

Zhang, Jiahui | Wang, Zhiwen ... - 《Acta biomaterialia》 - 2025,192 - 377～393 - 共17页

摘要： expression of MerTK, a cytosolic receptor, thus promoting | Plaque rupture in atherosclerosis (AS) is a | major cause of acute cardiovascular events. Macrophage | -induced inflammatory responses and accumulation of | excess reactive oxygen species (ROS) primarily induce

关键词： Atherosclerosis | Macrophages | Efferocytosis | Platelet membrane | Black phosphorus nanosheets

8. Development of a 3D Brain Model to Study Sex-Specific Neuroinflammation After Hemorrhagic Stroke NSTL国家科技图书文献中心

Islam, Rezwanul | Choudhary, Hadi Hasa...... - 《Translational stroke research》 - 2025,16(3) - 655～671 - 共17页 - 被引量：2

摘要： expression of CD206 and MerTK. Our in vitro, human, 3D cell | Subarachnoid hemorrhage (SAH) accounts for 5 | % of stroke, with women having a decreased | inflammatory response compared to men; however, this | mechanism has yet to be identified. One hurdle in SAH

关键词： 3D cell culture | Cerebrospinal fluid | Subarachnoid hemorrhage | Neuroinflammation | Microglia | Astrocytes | Neurons | Sex-specific

9. MERTK and Fibrosis: A New Target for Therapy NSTL国家科技图书文献中心

Pan, Ziyan | Eslam, Mohammed - 《DNA and Cell Biology》 - 2024,43(7) - 311～314 - 共4页 - 被引量：1

摘要： process. Mer tyrosine kinase (MERTK) was recently | provide an overview of the potential role of MERTK* as a* | Organ fibrosis is a devastating medical | challenge that is collectively responsible for an | estimated 45% of all deaths in developed countries and

关键词： MERTK | fibrosis | MAFLD | epigenetic | MECHANISMS

10. MerTK is a mediator of alpha-synuclein fibril uptake by human microglia NSTL国家科技图书文献中心

Dorion, Marie-France | Yaqubi, Moein ... - 《Brain: A journal of neurology》 - 2024,147(2) - 427～443 - 共17页 - 被引量：4

摘要：Mer tyrosine kinase (MerTK) is a receptor | , MerTK* is of importance in brain development* | explored the function of MerTK* in the microglial uptake* | -derived microglia, the MerTK-dependence of alpha | assessed through burden analysis of MERTK* variants and*

关键词： microglia | MerTK | alpha-synuclein | phagocytosis | Parkinson's disease | IDIOPATHIC PARKINSONS-DISEASE | NLRP3 INFLAMMASOME ACTIVATION | APOPTOTIC CELLS | TAM RECEPTORS | PHAGOCYTOSIS...

摘要： myeloid cells, TAM family members, particularly Mertk | study shows that Mertk expressed on human T cells | diversification of Mertk in immune regulation and its | While widely viewed as inhibitory receptors | that drive efferocytosis and immune resolution on