NSTL国家科技图书文献中心

1. Revealing the Deterioration Effect of Scale Inhibitor on the Performance of Corrosion Inhibitor under Dynamic Conditions NSTL国家科技图书文献中心

Chen, Hui | Wang, Xiaodong ... - 《Journal of Materials Engineering and Performance》 - 2025,34(3) - 2145～2155 - 共11页

摘要：Currently, the scale inhibitor* (SI) and* | corrosion inhibitor* (CI) have been massively applied in* | the oil gathering and transportation applications | , however, their effect on the corrosion of pipeline | steels remained vague. Herein, the corrosion behavior

关键词： adsorption | antagonism | CO2-H2S corrosion | corrosion inhibitor | velocity

2. Structure of Plasmodium vivaxN‐myristoyltransferase with inhibitor IMP‐1088: exploring an NMT inhibitor for antimalarial therapy NSTL国家科技图书文献中心

Alex Mendez | Cydni Bolling ... - 《Acta crystallographica,Structural biology communications.Section F》 - 2025,81(1) - 1～10 - 共10页

摘要： validated NMT inhibitor, is reported. IMP‐1088 is a | validated nonpeptidic inhibitor* and a ternary complex* | Plasmodium vivax, a significant contributor to | global malaria cases, poses an escalating health burden | on a substantial portion of the world's population

关键词： N‐myristoyltransferases | Plasmodium vivax | inhibitor complexes | drug repurposing | malaria

3. Synthesis and evaluation of new type plant extraction corrosion inhibitor NSTL国家科技图书文献中心

Zhang, Zhi | Feng, Xiaoxiao - 《Geoenergy Science and Engineering》 - 2025,245 - 共7页

摘要： inhibitor was synthesized, firstly, the purple sweet | corrosion inhibitor* through condensation extraction and* | performance of the inhibitor* was evaluated by the loss-in* | inhibitor, and the corrosion inhibition rate can be known | with the increase of corrosion inhibitor

关键词： N80 steel | Corrosion | Plant | Corrosion inhibitor

4. Gut microbiome and immune checkpoint inhibitor toxicity NSTL国家科技图书文献中心

Verheijden, Rik J. | van Eijs, Mick J. M.... - 《European journal of cancer》 - 2025,216 - Article 115221～Article 115221 - 共11页

摘要： inhibitor (ICI) efficacy, but its association with immune | Background: Multiple studies have suggested | that gut microbiome may influence immune checkpoint | -related adverse events (irAEs) is less well studied. In | this prospective cohort study, we assessed whether

关键词： Checkpoint inhibitor | Immune-related adverse event | Toxicity | Microbiome

5. Nitric oxide is an irreversible human diamine oxidase inhibitor NSTL国家科技图书文献中心

Kosta, Felix | Gludovacz, Elisabeth ... - 《Free radical research》 - 2025,59(2) - 138～151 - 共14页

摘要： DAO inhibitor* in vitro representing the first* | discovered natural inhibitor* for this enzyme. Endogenous* | inhibitors diminazene and ciproxifan, the substrates | Diamine oxidase (DAO) histamine-degradation | rates are compromised in plasma of mastocytosis

关键词： Nitric oxide | diamine oxidase | enzyme inhibitor | topaquinone | mast cell activation

6. IgLON5 autoimmunity secondary to immune checkpoint inhibitor NSTL国家科技图书文献中心

Itoh, Christopher | Swart, Grace ... - 《Journal of Neuroimmunology》 - 2025,399 - 578516～578516 - 共4页

摘要： induced by immune checkpoint inhibitors* (ICI). We* | inhibitors (ICI) may promote the development of IgLON5 | IgLON5 autoimmunity is characterized by a | diverse range of clinical presentations, including | neuropsychiatric symptoms, sleep disturbances, gait instability

关键词： Autoimmune encephalitis | Immune checkpoint inhibitor | Immune mediated adverse event

7. DEFINE: A Prospective, Randomized, Phase 4 Trial to Assess a Protease Inhibitor–Based Regimen Switch Strategy to Manage Integrase Inhibitor–Related Weight Gain NSTL国家科技图书文献中心

David,Anderson | Moti,Ramgopal ... - 《Clinical infectious diseases》 - 2025,80(3) - 602～612 - 共11页 - 被引量：1

摘要： inhibitor (INSTI)–based antiretroviral (ARV) therapies | those on protease inhibitor* (PI)–based regimens. The* | Abstract Background Integrase strand transfer | have been associated with greater weight gain in | people with human immunodeficiency virus (HIV) versus

关键词： Antiretroviral | Human immunodefiiciency virus | Integrase strand transfer inhibitor | Protease inhibitor | Weight

8. Effect-Directed Synthesis of a Dithioacetal Tyrosinase Inhibitor NSTL国家科技图书文献中心

Escalante, Andrea M. | Riera, Micaela B.... - 《European journal of organic chemistry》 - 2025,28(1) - n/a～n/a - 共4页

摘要： readily accessible dithioacetal inhibitor* of tyrosinase* | Traditional methods for discovering bioactive | compounds can be time-consuming and resource-intensive | , often requiring extensive synthesis and evaluation. To | address these challenges, this study combines TLC-based

关键词： Dithioacetal | Effect-directed | Tyrosinase-inhibitor | Thin-layer-chromatography

9. Capivasertib: First Approved AKT inhibitor for the Treatment of Patients with Breast Cancer NSTL国家科技图书文献中心

De, Surya K. - 《Anti-cancer agents in medicinal chemistry》 - 2025,25(6) - 371～377 - 共7页

摘要： first AKT inhibitor, was authorized by the US FDA on | Breast cancer frequently occurs in women | . Among the several types of breast cancers, almost 50 | % of breast cancers are caused by one or more gene | mutations of the PI3K/mTOR/AKT pathway. Capivasertib, the

关键词： Breast cancer | capivasertib | AKT inhibitor | PI3K inhibitor | pharmacokinetics | drug metabolism

10. Endocrine effects of MEK and BRAF inhibitor therapy in paediatric patients: a tertiary centre experience NSTL国家科技图书文献中心

Bin Jalal, Arif Hana... | Gunn, Harriet ... - 《Journal of neuro-oncology.》 - 2025,172(1) - 257～263 - 共7页

摘要： inhibitor) and trametinib (MEK inhibitor) from January | Purpose BRAF and MEK inhibitors* are used to* | BRAF and MEK inhibitors* at the largest paediatric* | treat a range of paediatric tumours including low | -grade gliomas. The ubiquitous nature of the BRAF/MAPK

摘要：Currently, the scale inhibitor* (SI) and* | corrosion inhibitor* (CI) have been massively applied in* | the oil gathering and transportation applications | , however, their effect on the corrosion of pipeline | steels remained vague. Herein, the corrosion behavior

关键词： adsorption | antagonism | CO2-H2S corrosion | corrosion inhibitor | velocity

摘要： validated NMT inhibitor, is reported. IMP‐1088 is a | validated nonpeptidic inhibitor* and a ternary complex* | Plasmodium vivax, a significant contributor to | global malaria cases, poses an escalating health burden | on a substantial portion of the world's population

关键词： N‐myristoyltransferases | Plasmodium vivax | inhibitor complexes | drug repurposing | malaria

摘要： inhibitor was synthesized, firstly, the purple sweet | corrosion inhibitor* through condensation extraction and* | performance of the inhibitor* was evaluated by the loss-in* | inhibitor, and the corrosion inhibition rate can be known | with the increase of corrosion inhibitor

关键词： N80 steel | Corrosion | Plant | Corrosion inhibitor

摘要： inhibitor (ICI) efficacy, but its association with immune | Background: Multiple studies have suggested | that gut microbiome may influence immune checkpoint | -related adverse events (irAEs) is less well studied. In | this prospective cohort study, we assessed whether

关键词： Checkpoint inhibitor | Immune-related adverse event | Toxicity | Microbiome

摘要： DAO inhibitor* in vitro representing the first* | discovered natural inhibitor* for this enzyme. Endogenous* | inhibitors diminazene and ciproxifan, the substrates | Diamine oxidase (DAO) histamine-degradation | rates are compromised in plasma of mastocytosis

关键词： Nitric oxide | diamine oxidase | enzyme inhibitor | topaquinone | mast cell activation

摘要： induced by immune checkpoint inhibitors* (ICI). We* | inhibitors (ICI) may promote the development of IgLON5 | IgLON5 autoimmunity is characterized by a | diverse range of clinical presentations, including | neuropsychiatric symptoms, sleep disturbances, gait instability

关键词： Autoimmune encephalitis | Immune checkpoint inhibitor | Immune mediated adverse event

摘要： inhibitor (INSTI)–based antiretroviral (ARV) therapies | those on protease inhibitor* (PI)–based regimens. The* | Abstract Background Integrase strand transfer | have been associated with greater weight gain in | people with human immunodeficiency virus (HIV) versus

关键词： Antiretroviral | Human immunodefiiciency virus | Integrase strand transfer inhibitor | Protease inhibitor | Weight

摘要： readily accessible dithioacetal inhibitor* of tyrosinase* | Traditional methods for discovering bioactive | compounds can be time-consuming and resource-intensive | , often requiring extensive synthesis and evaluation. To | address these challenges, this study combines TLC-based

关键词： Dithioacetal | Effect-directed | Tyrosinase-inhibitor | Thin-layer-chromatography

摘要： first AKT inhibitor, was authorized by the US FDA on | Breast cancer frequently occurs in women | . Among the several types of breast cancers, almost 50 | % of breast cancers are caused by one or more gene | mutations of the PI3K/mTOR/AKT pathway. Capivasertib, the

关键词： Breast cancer | capivasertib | AKT inhibitor | PI3K inhibitor | pharmacokinetics | drug metabolism

摘要： inhibitor) and trametinib (MEK inhibitor) from January | Purpose BRAF and MEK inhibitors* are used to* | BRAF and MEK inhibitors* at the largest paediatric* | treat a range of paediatric tumours including low | -grade gliomas. The ubiquitous nature of the BRAF/MAPK

关键词： Hyponatraemia | MEK inhibitor | BRAF inhibitor | Paediatric oncology | Paediatric endocrinology | MAPK/ERK pathway

4008-161-200 800-990-8900

国家科技图书文献中心

摘要：Currently, the scale inhibitor (SI) and | corrosion inhibitor (CI) have been massively applied in | the oil gathering and transportation applications | , however, their effect on the corrosion of pipeline | steels remained vague. Herein, the corrosion behavior

关键词： adsorption | antagonism | CO2-H2S corrosion | corrosion inhibitor | velocity

摘要： validated NMT inhibitor, is reported. IMP‐1088 is a | validated nonpeptidic inhibitor and a ternary complex | Plasmodium vivax, a significant contributor to | global malaria cases, poses an escalating health burden | on a substantial portion of the world's population

关键词： N‐myristoyltransferases | Plasmodium vivax | inhibitor complexes | drug repurposing | malaria

摘要： inhibitor was synthesized, firstly, the purple sweet | corrosion inhibitor through condensation extraction and | performance of the inhibitor was evaluated by the loss-in | inhibitor, and the corrosion inhibition rate can be known | with the increase of corrosion inhibitor

关键词： N80 steel | Corrosion | Plant | Corrosion inhibitor

摘要： inhibitor (ICI) efficacy, but its association with immune | Background: Multiple studies have suggested | that gut microbiome may influence immune checkpoint | -related adverse events (irAEs) is less well studied. In | this prospective cohort study, we assessed whether

关键词： Checkpoint inhibitor | Immune-related adverse event | Toxicity | Microbiome

摘要： DAO inhibitor in vitro representing the first | discovered natural inhibitor for this enzyme. Endogenous | inhibitors diminazene and ciproxifan, the substrates | Diamine oxidase (DAO) histamine-degradation | rates are compromised in plasma of mastocytosis

关键词： Nitric oxide | diamine oxidase | enzyme inhibitor | topaquinone | mast cell activation

摘要： induced by immune checkpoint inhibitors (ICI). We | inhibitors (ICI) may promote the development of IgLON5 | IgLON5 autoimmunity is characterized by a | diverse range of clinical presentations, including | neuropsychiatric symptoms, sleep disturbances, gait instability

关键词： Autoimmune encephalitis | Immune checkpoint inhibitor | Immune mediated adverse event

摘要： inhibitor (INSTI)–based antiretroviral (ARV) therapies | those on protease inhibitor (PI)–based regimens. The | Abstract Background Integrase strand transfer | have been associated with greater weight gain in | people with human immunodeficiency virus (HIV) versus

关键词： Antiretroviral | Human immunodefiiciency virus | Integrase strand transfer inhibitor | Protease inhibitor | Weight

摘要： readily accessible dithioacetal inhibitor of tyrosinase | Traditional methods for discovering bioactive | compounds can be time-consuming and resource-intensive | , often requiring extensive synthesis and evaluation. To | address these challenges, this study combines TLC-based

关键词： Dithioacetal | Effect-directed | Tyrosinase-inhibitor | Thin-layer-chromatography

摘要： first AKT inhibitor, was authorized by the US FDA on | Breast cancer frequently occurs in women | . Among the several types of breast cancers, almost 50 | % of breast cancers are caused by one or more gene | mutations of the PI3K/mTOR/AKT pathway. Capivasertib, the

关键词： Breast cancer | capivasertib | AKT inhibitor | PI3K inhibitor | pharmacokinetics | drug metabolism

摘要： inhibitor) and trametinib (MEK inhibitor) from January | Purpose BRAF and MEK inhibitors are used to | BRAF and MEK inhibitors at the largest paediatric | treat a range of paediatric tumours including low | -grade gliomas. The ubiquitous nature of the BRAF/MAPK

关键词： Hyponatraemia | MEK inhibitor | BRAF inhibitor | Paediatric oncology | Paediatric endocrinology | MAPK/ERK pathway

4008-161-200 800-990-8900

国家科技图书文献中心

摘要：Currently, the scale inhibitor* (SI) and* | corrosion inhibitor* (CI) have been massively applied in* | the oil gathering and transportation applications | , however, their effect on the corrosion of pipeline | steels remained vague. Herein, the corrosion behavior

摘要： validated NMT inhibitor, is reported. IMP‐1088 is a | validated nonpeptidic inhibitor* and a ternary complex* | Plasmodium vivax, a significant contributor to | global malaria cases, poses an escalating health burden | on a substantial portion of the world's population

摘要： inhibitor was synthesized, firstly, the purple sweet | corrosion inhibitor* through condensation extraction and* | performance of the inhibitor* was evaluated by the loss-in* | inhibitor, and the corrosion inhibition rate can be known | with the increase of corrosion inhibitor

摘要： DAO inhibitor* in vitro representing the first* | discovered natural inhibitor* for this enzyme. Endogenous* | inhibitors diminazene and ciproxifan, the substrates | Diamine oxidase (DAO) histamine-degradation | rates are compromised in plasma of mastocytosis

摘要： induced by immune checkpoint inhibitors* (ICI). We* | inhibitors (ICI) may promote the development of IgLON5 | IgLON5 autoimmunity is characterized by a | diverse range of clinical presentations, including | neuropsychiatric symptoms, sleep disturbances, gait instability

摘要： inhibitor (INSTI)–based antiretroviral (ARV) therapies | those on protease inhibitor* (PI)–based regimens. The* | Abstract Background Integrase strand transfer | have been associated with greater weight gain in | people with human immunodeficiency virus (HIV) versus

摘要： readily accessible dithioacetal inhibitor* of tyrosinase* | Traditional methods for discovering bioactive | compounds can be time-consuming and resource-intensive | , often requiring extensive synthesis and evaluation. To | address these challenges, this study combines TLC-based

摘要： inhibitor) and trametinib (MEK inhibitor) from January | Purpose BRAF and MEK inhibitors* are used to* | BRAF and MEK inhibitors* at the largest paediatric* | treat a range of paediatric tumours including low | -grade gliomas. The ubiquitous nature of the BRAF/MAPK