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1. Role of mitophagy in intervertebral disc degeneration: A narrative review NSTL国家科技图书文献中心

Wu, Zuo-long |  Liu, Yong... -  《Osteoarthritis and cartilage》 - 2025,33(1) - 27~41 - 共15页

摘要: disc (IVD) degeneration (IDD) has become increasingly |  the initiation and progression of intervertebral | Objective: The pivotal role of mitophagy in |  apparent due to a growing body of research on its |  pathogenesis. This review summarizes the role of mitophagy in
关键词: Mitophagy |  Intervertebral disc degeneration |  Intervertebral disc |  Autophagy lysosomes |  Nucleus pulposus

2. 3D printed PGCL@PLA/10CSPL composite scaffolds loaded with fibronectin 1 for intervertebral disc degeneration treatment NSTL国家科技图书文献中心

Zhang, Weilin |  Chen, Siyuan... -  《Biofabrication》 - 2025,17(1) - 共14页

摘要: function is essential for intervertebral disc | Restoration of disc height and biomechanical |  degeneration (IDD) treatment. Removing abnormal nucleus |  associated with NP degeneration. A novel poly(glycolide-co |  the abnormal NP degeneration. In vitro and in vivo
关键词: intervertebral disc degeneration |  fibronectin 1 |  poly(glycolide-co-caprolactone)

3. Causal effects of plasma proteome on intervertebral disc degeneration: a comprehensive mendelian randomization study NSTL国家科技图书文献中心

Bo-Wen,Ren |  Yi-Hao,Liu... -  《European spine journal》 - 2025,34(1) - 316~325 - 共10页 - 被引量:1

摘要:Abstract Purpose Intervertebral disc |  degeneration (IVDD) considerably impacts global disability |  and quality of life. Although potential links |  between plasma proteins and IVDD exist, their causal |  correlation remains undefined. This study explored the
关键词: Plasma proteome |  Mendelian randomization |  Intervertebral disc degeneration |  Causal association

4. Impaired degradation of PLCG1 by chaperone-mediated autophagy promotes cellular senescence and intervertebral disc degeneration NSTL国家科技图书文献中心

Cheng, Zhangrong |  Gan, Weikang... -  《Autophagy》 - 2025,21(2) - 352~373 - 共22页

摘要: intervertebral disc degeneration. Based on structural and | : intervertebral disc; IVDD: intervertebral disc degeneration; KD | -induced disc degeneration in rats was inhibited by |  common features of disc degeneration and other age |  was associated with disc senescence, and the TNF
关键词: Calcium overload |  chaperone-mediated autophagy |  intervertebral disc degeneration |  senescence |  nucleus pulposus

5. Machine learning-based analysis of programmed cell death types and key genes in intervertebral disc degeneration NSTL国家科技图书文献中心

Lv, Yigang |  Du, Jiawei... -  《Apoptosis》 - 2025,30(1/2) - 250~266 - 共17页

摘要:Intervertebral disc degeneration (IVDD) is |  contributing to disc degeneration. Core genes were identified |  correlation with the severity of disc degeneration |  reduced apoptosis and delayed disc degeneration |  molecular pathology of disc degeneration and suggest
关键词: Intervertebral disc degeneration |  Programmed cell death |  Bioinformatics |  Therapeutic targets |  Machine learning

6. Implications of circadian disruption on intervertebral disc degeneration: The mediating role of sympathetic nervous system NSTL国家科技图书文献中心

Song, Zongmian |  Yan, Miaoheng... -  《Ageing Research Reviews》 - 2025,104 - 102633~102633 - 共16页

摘要: ascribed to intervertebral disc degeneration (IVDD). The |  intervertebral disc (IVD) exhibits rhythmic physiological | The circadian clock orchestrates a broad |  spectrum of physiological processes, crucially modulating |  human biology across an approximate 24-hour cycle. The
关键词: Intervertebral disc degeneration |  Circadian rhythm |  Circadian clock |  Sympathetic nervous system |  Chronotherapy

7. Rejuvenation Modulation of Nucleus Pulposus Progenitor Cells Reverses Senescence-Associated Intervertebral Disc Degeneration NSTL国家科技图书文献中心

Da-wang Zhao |  Jing Zhang... -  《Advanced Materials》 - 2025,37(7) - 2409979.1~2409979.15 - 共15页

摘要: to resist intervertebral disc degeneration (IVDD |  of degenerated intervertebral discs. In summary | The decreased regeneration potential of aging |  nucleus pulposus resident progenitor cells (NPPCs) fails | ), and strategies to remodel the regeneration capacity
关键词: -Klotho |  aging cell reinvigoration |  circRNA |  intervertebral disc degeneration |  nucleus pulposus progenitor cells

8. Potential causal association between serum vitamin D levels and intervertebral disc degeneration: A mendelian randomization study NSTL国家科技图书文献中心

Libangxi Liu |  Chao Sun... -  《Journal of orthopaedic science》 - 2025,30(3) - 433~439 - 共7页

摘要:Objectives: Intervertebral disc degeneration |  (IDD) is a prevalent musculoskeletal disorder with |  substantial implications for disability and healthcare |  expenditures. The role of serum vitamin D (25-Hydroxyvitamin |  D, 25(OH)D) levels in the pathogenesis of various
关键词: 25-Hydroxyvitamin D; Genome-wide association studies; Intervertebral disc degeneration

9. Application of Self-Healing Hydrogels in the Treatment of Intervertebral Disc Degeneration NSTL国家科技图书文献中心

Guo, Cunliang |  Jiao, Xinyi... -  《Journal of biomedical materials research.,Part B,.Applied biomaterials.》 - 2025,113(2) - e35532~e35532 - 共20页

摘要:Intervertebral disc degeneration (IDD) is one | , offering new hope for disc repair due to their | , intervertebral discs are often damaged by trauma or |  the mechanical properties of natural intervertebral |  of the leading causes of chronic pain and
关键词: cell delivery |  drug delivery systems |  exosomes |  intervertebral disc degeneration |  self-healing hydrogels |  tissue engineering |  self‐healing hydrogels

10. Integration of bioinformatics and multi-layered experimental validation reveals novel functions of acetylation-related genes in intervertebral disc degeneration NSTL国家科技图书文献中心

Zhu, Jun |  Song, Tongqu... -  《Gene》 - 2025,933 - 148974~148974 - 共23页

摘要: underlying intervertebral disc degeneration (IDD) remain |  degrees of degeneration were collected to corroborate | Background: The molecular mechanisms |  poorly understood. The purpose of this work is to |  elucidate key molecules and investigate the roles of
关键词: Intervertebral disc degeneration |  Acetylation |  Immune infiltration |  Hub gene |  Bioinformatics analysis
检索条件Intervertebral Disc Degeneration
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