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1. Pulmonary Hypertension Associated with Interstitial Lung Disease (PH-ILD): Back to the Future NSTL国家科技图书文献中心

Fiorentu, Giordano |  Bernardinello, Nicol... -  《Advances in therapy.》 - 2025,42(4) - 1627 ~1641 - 共15页

摘要: INCREASE trial of inhaled treprostinil has recently | Pulmonary hypertension (PH) is a progressive |  syndrome characterized by increased pulmonary artery |  pressure. PH often complicates chronic lung diseases | , thus contributing to a substantial disease burden and
关键词: Pulmonary hypertension |  Interstitial lung disease |  Chronic lung diseases |  Treprostinil |  Treatment |  Therapy

2. Efficacy and determinants of response to inhaled treprostinil in pulmonary hypertension - interstitial lung disease NSTL国家科技图书文献中心

Balakrishnan, Bathma... |  Azar, Jehad... -  《Respiratory medicine》 - 2024,234 - 107835~107835 - 共9页

摘要:Inhaled treprostinil has shown to improve | , treatment with inhaled treprostinil for six months |  associated with favorable response to inhaled treprostinil |  and determinants of favorable response to inhaled |  treprostinil at six months. Methods: Of the 106 patients
关键词: Interstitial lung disease |  Pulmonary hypertension |  Survival |  Transplantation |  Treatment

3. Inhaled treprostinil in pulmonary hypertension associated with COPD: PERFECT study results NSTL国家科技图书文献中心

Nathan, Steven D. |  Argula, Rahul... -  《The European respiratory journal :》 - 2024,63(6) - 2400172~2400172 - 共6页 - 被引量:3

摘要: of inhaled treprostinil (iTRE) in this patient | Background Pulmonary hypertension (PH | ) accompanying COPD (PH-COPD) is associated with worse outcomes |  than COPD alone. There are currently no approved |  therapies to treat PH-COPD. The PERFECT study
关键词: DISEASE |  THERAPY |  SILDENAFIL

4. Survival analysis from the INCREASE study in PH-ILD: evaluating the impact of treatment crossover on overall mortality NSTL国家科技图书文献中心

Nathan, Steven D. |  Johri, Shilpa... -  《Thorax: The Journal of the British Thoracic Society》 - 2024,79(4) - 301~306 - 共6页 - 被引量:2

摘要: to evaluate whether inhaled treprostinil has a long |  and 12 deaths in the inhaled treprostinil and |  inhaled treprostinil and there were 29 and 33 deaths in |  the prior inhaled treprostinil arm and prior placebo |  reductions in death associated with inhaled treprostinil
关键词: Rare lung diseases |  Primary Pulmonary Hypertension |  Idiopathic pulmonary fibrosis |  IDIOPATHIC PULMONARY-FIBROSIS |  INHALED TREPROSTINIL |  LUNG-DISEASE |  HYPERTENSION |  PROGRESSION |  TRIAL

5. Promising advances in treatments for the management of idiopathic pulmonary fibrosis NSTL国家科技图书文献中心

Sofia, Carmelo |  Comes, Alessia... -  《Expert opinion on pharmacotherapy》 - 2024,25(1/6) - 717~725 - 共9页 - 被引量:1

摘要: and inhaled treprostinil. The literature search | IntroductionFollowing the INPULSIS and ASCEND |  studies, leading to the first two approved antifibrotic |  therapies for patients with IPF, ongoing investigations |  are firmly exploring novel agents for a targeted
关键词: Antifibrotic therapies |  BI 1015550 |  fibrotic pathways |  idiopathic pulmonary fibrosis |  treprostinil |  clinical trials |  study endpoints |  trial design |  INHALED TREPROSTINIL |  AUTOTAXIN INHIBITOR...

6. Evidence from recent clinical trials in fibrotic interstitial lung diseases NSTL国家科技图书文献中心

Vincent Cottin |  Claudia Valenzuela -  《Current opinion in pulmonary medicine》 - 2024,30(5) - 484~493 - 共10页 - 被引量:2

摘要: acid receptor antagonist; inhaled treprostinil, a | , admilparant, inhaled treprostinil, and inhaled AP01 | Purpose of review:Idiopathic pulmonary |  fibrosis (IPF) is the prototype of fibrosing interstitial |  lung diseases. It is mirrored by progressive
关键词: clinical trials |  lysophosphatidyl acid |  monoclonal antibody |  pulmonary fibrosis

7. Treprostinil palmitil inhalation powder leverages endogenous lung enzymes to provide sustained treprostinil NSTL国家科技图书文献中心

Nguyen, Tam |  Chang, Christina... -  《Expert opinion on drug delivery》 - 2024,21(7/12) - 1297~1305 - 共9页

摘要: treprostinil palmitil (TP) conversion to treprostinil and the | BackgroundTo determine key enzymes enabling |  main converting sites in the respiratory |  system.Research Design and MethodsWe performed in vitro activity |  assays to identify lung enzymes hydrolyzing TP, and
关键词: Inhaled therapy biological barriers |  lung enzymes |  pulmonary hypertension |  treprostinil palmitil inhalation powder |  sustained treprostinil release

8. Antifibrotic therapy in progressive pulmonary fibrosis: a review of recent advances NSTL国家科技图书文献中心

Naqvi, Marium |  Hannah, Jennifer... -  《Expert review of respiratory medicine.》 - 2024,18(1/6) - 397~407 - 共11页

摘要:IntroductionProgressive pulmonary fibrosis |  (PPF) is a manifestation of a heterogenous group of |  underlying interstitial lung disease (ILD) diagnoses | , defined as non-idiopathic pulmonary fibrosis (IPF | ) progressive fibrotic ILD meeting at least two of the
关键词: Antifibrotics |  nintedanib |  pirfenidone |  pulmonary fibrosis |  progressive pulmonary fibrosis |  interstitial lung disease |  INTERSTITIAL LUNG-DISEASE |  FORCED VITAL CAPACITY |  RESPIRATORY SOCIETY STATEMENT |  QUALITY-OF-LIFE...

9. Pulmonary Hypertension Associated with Chronic Lung Disease NSTL国家科技图书文献中心

Wang, Yuanchen |  Estrada, Rodolfo A.... -  《Current respiratory medicine reviews》 - 2024,20(2) - 171~184 - 共14页

摘要:Patients with Chronic Lung Disease (CLD) are |  frequently burdened by pulmonary hypertension (PH), which |  is associated with reduced functional capacity | , poor quality of life, increased oxygen requirements | , and increased morbidity and mortality. The
关键词: Pulmonary hypertension |  pulmonary arterial hypertension |  chronic obstructive pulmonary disease |  interstitial lung disease |  obstructive sleep apnea |  pathophysiology |  diagnosis |  management |  OBSTRUCTIVE SLEEP-APNEA |  POSITIVE AIRWAY PRESSURE...

10. Plain language summary of the INCREASE study: inhaled treprostinil (Tyvaso) for the treatment of pulmonary hypertension due to interstitial lung disease NSTL国家科技图书文献中心

West, Natalie |  Smoot, Karen... -  《Future cardiology》 - 2023,19(5) - 229~239 - 共11页

摘要: study. Half the participants took inhaled treprostinil |  took inhaled treprostinil could walk around 31 meters |  placebo. Participants taking inhaled treprostinil also |  higher levels. Participants taking inhaled treprostinil | %) compared to participants taking inhaled treprostinil
关键词: interstitial lung disease |  lay summary |  plain language summary |  pulmonary hypertension |  treprostinil
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