NSTL国家科技图书文献中心

1. Epigenetic modifications in drug-induced liver injury: A systematic review NSTL国家科技图书文献中心

Romina Lorena de los... | Antonio Segovia-Zafr...... - 《British Journal of Clinical Pharmacology》 - 2025,91(6) - 1660～1674 - 共15页

摘要： idiosyncratic drug-induced* liver injury, a potentially severe | involved. Drug-induced liver injury epigenetic signatures* | studies in drug-induced* liver injury. The main inclusion | -induced liver injury with significant risk association* | analysis between drug-induced* liver injury and an*

关键词： DNA methylation; antituberculosis drug‐induced liver injury; drug‐induced liver injury

2. Drug-Induced Liver Injury in Patients With Chronic Liver Disease NSTL国家科技图书文献中心

Ghabril, Marwan | Vuppalanchi, Raj ... - 《Liver international》 - 2025,45(3) - e70019～e70019 - 共13页

摘要：ObjectiveDrug-induced* liver injury (DILI) is a* | is clinically challenging, and liver* injury can be* | more severe liver* injury and worse outcomes after* | severe leading to liver failure, death, or liver | transplantation. Patients with underlying chronic liver* diseases*

关键词： acute-on-chronic liver failure | chronic liver disease | drug-induced liver injury | acute‐on‐chronic liver failure | drug‐induced liver injury

3. Liver Injury due to Intravenous Methylprednisolone in the Drug-Induced Liver Injury Network NSTL国家科技图书文献中心

Ahmad, Jawad | Li, Yi-Ju ... - 《Liver international》 - 2025,45(2) - e16242～e16242 - 共9页 - 被引量：2

摘要： induced liver injury (DILI). The aim of this study was | % were jaundiced; and all had hepatocellular injury | sclerosis (MS). Liver* biopsies in 7 cases revealed mild* | ).ConclusionMP DILI is characterised by hepatocellular injury | Background and AimsShort courses of

关键词： drug induced liver injury | HLA genotype associations | methylprednisolone | multiple sclerosis

4. Challenges in herbal‐induced liver injury identification and prevention NSTL国家科技图书文献中心

Dina Halegoua‐DeMarz... | Victor Navarro - 《Liver international》 - 2025,45(3) - e16071～e16071 - 共6页

摘要：. Mirroring this trend, HDS‐induced* liver injury, also known | as HDS‐induced liver injury (HILI), has increased* | % of cases of drug‐induced* liver injury (DILI). There* | Liver Injury Network (DILIN), now accounting for 20 | significantly over the past three decades in the Drug‐Induced

关键词： drug‐induced liver injury | hepatotoxicity | herbal and dietary supplements

5. Identification of Distinguishing Features of Drug‐Induced Liver Injury and Liver Injury Associated With Sepsis NSTL国家科技图书文献中心

Egill Logason | Sigurdur Sölvi Sigur...... - 《Liver international》 - 2025,45(5) - e70090～e70090 - 共11页

摘要： difficult to distinguish between drug‐induced liver injury | induced liver injury, SILI). The aims of the study were | (DILI) and liver* injury associated with sepsis (sepsis* | with a HC pattern of liver* injury favours the* | with markers of more pronounced liver* injury.*

关键词： drug‐induced liver injury | hepatotoxicity | liver injury | sepsis

6. Drug-Induced Liver Injury Associated With Emerging Cancer Therapies NSTL国家科技图书文献中心

Chodup, Piotr | Samodelov, Sophia L.... - 《Liver international》 - 2025,45(2) - e70002～e70002 - 共14页 - 被引量：1

摘要： liver injury (DILI) risk assessment in the preclinical | . While liver* test abnormalities are rather common in* | not well understood, complicating the drug-induced | mechanisms of liver* toxicity, are described here to the* | oncology, where standard liver* signals during drug*

关键词： CAR‐T cell therapy | covalent tyrosine kinase inhibitors | cTKI | DILI | drug‐induced liver injury | ILICI | immune checkpoint inhibitors | CAR-T cell therapy | drug-induced liver injury

7. Methods for causality assessment of idiosyncratic drug‐induced liver injury NSTL国家科技图书文献中心

Miren García‐Cortés | Gonzalo Matilla‐Cabe...... - 《Liver international》 - 2025,45(3) - e16083～e16083 - 共13页

摘要：‐induced* liver injury (DILI) is a challenging task due to* | imaging tests to exclude other causes of liver injury | Abstract The diagnosis of idiosyncratic drug | the lack of specific features or definitive | diagnostic tools. A minimum of clinical and pharmacological

关键词： causality assessment methods | hepatotoxicity | idiosyncratic drug‐induced liver injury | RECAM | RUCAM | structured expert opinion

8. Innate immune regulation in inflammation resolution and liver regeneration in drug-induced liver injury NSTL国家科技图书文献中心

Yihan,Qian | Jie,Zhao ... - 《Archives of Toxicology》 - 2025,99(1) - 115～126 - 共12页

摘要：Abstract Drug-induced* liver injury (DILI) is* | an acute liver* injury that poses a significant* | injury and liver regeneration stages of DILI. This | progress into chronic DILI or even lead to liver* failure* | hepatocytes, the immune responses and liver* inflammation*

关键词： Drug-induced liver injury | Innate immune regulation | Inflammation resolution | Liver regeneration

9. A selective mitochondria-targeted fluorescent probe for imaging cysteine in drug-induced liver injury NSTL国家科技图书文献中心

Qin, Guixin | Gao, Lingli ... - 《Talanta》 - 2025,282 - 共8页

摘要： the early diagnosis of drug-induced liver injury | successfully applied in imaging of Cys in drug-induced liver | injury in vivo. The research demonstrated that HPXI-6C | Cysteine (Cys) is involved in many | physiological processes. It's challenging to detect Cys

关键词： Fluorescent probe | Cysteine | Fluorescent imaging | Drug-induced liver injury

10. Drug-induced liver injury associated with pretomanid, bedaquiline, and linezolid: Insights from FAERS database analysis NSTL国家科技图书文献中心

He, Qingfeng | Li, Yang ... - 《British Journal of Clinical Pharmacology》 - 2025,91(3) - 799～807 - 共9页

摘要： liver injury (DILI) with the BPaL regimen compared to | study investigated the association of drug-induced | Aims: The emergence of drug-resistant | tuberculosis has necessitated novel treatments like the | pretomanid, bedaquiline and linezolid (BPaL) regimen. This

关键词： DNA methylation; antituberculosis drug‐induced liver injury; drug‐induced liver injury

摘要：ObjectiveDrug-induced* liver injury (DILI) is a* | is clinically challenging, and liver* injury can be* | more severe liver* injury and worse outcomes after* | severe leading to liver failure, death, or liver | transplantation. Patients with underlying chronic liver* diseases*

关键词： acute-on-chronic liver failure | chronic liver disease | drug-induced liver injury | acute‐on‐chronic liver failure | drug‐induced liver injury

摘要： induced liver injury (DILI). The aim of this study was | % were jaundiced; and all had hepatocellular injury | sclerosis (MS). Liver* biopsies in 7 cases revealed mild* | ).ConclusionMP DILI is characterised by hepatocellular injury | Background and AimsShort courses of

关键词： drug induced liver injury | HLA genotype associations | methylprednisolone | multiple sclerosis

关键词： drug‐induced liver injury | hepatotoxicity | herbal and dietary supplements

摘要： difficult to distinguish between drug‐induced liver injury | induced liver injury, SILI). The aims of the study were | (DILI) and liver* injury associated with sepsis (sepsis* | with a HC pattern of liver* injury favours the* | with markers of more pronounced liver* injury.*

关键词： drug‐induced liver injury | hepatotoxicity | liver injury | sepsis

摘要： liver injury (DILI) risk assessment in the preclinical | . While liver* test abnormalities are rather common in* | not well understood, complicating the drug-induced | mechanisms of liver* toxicity, are described here to the* | oncology, where standard liver* signals during drug*

关键词： CAR‐T cell therapy | covalent tyrosine kinase inhibitors | cTKI | DILI | drug‐induced liver injury | ILICI | immune checkpoint inhibitors | CAR-T cell therapy | drug-induced liver injury

摘要：‐induced* liver injury (DILI) is a challenging task due to* | imaging tests to exclude other causes of liver injury | Abstract The diagnosis of idiosyncratic drug | the lack of specific features or definitive | diagnostic tools. A minimum of clinical and pharmacological

关键词： causality assessment methods | hepatotoxicity | idiosyncratic drug‐induced liver injury | RECAM | RUCAM | structured expert opinion

摘要：Abstract Drug-induced* liver injury (DILI) is* | an acute liver* injury that poses a significant* | injury and liver regeneration stages of DILI. This | progress into chronic DILI or even lead to liver* failure* | hepatocytes, the immune responses and liver* inflammation*

关键词： Drug-induced liver injury | Innate immune regulation | Inflammation resolution | Liver regeneration

摘要： the early diagnosis of drug-induced liver injury | successfully applied in imaging of Cys in drug-induced liver | injury in vivo. The research demonstrated that HPXI-6C | Cysteine (Cys) is involved in many | physiological processes. It's challenging to detect Cys

关键词： Fluorescent probe | Cysteine | Fluorescent imaging | Drug-induced liver injury

摘要： liver injury (DILI) with the BPaL regimen compared to | study investigated the association of drug-induced | Aims: The emergence of drug-resistant | tuberculosis has necessitated novel treatments like the | pretomanid, bedaquiline and linezolid (BPaL) regimen. This

关键词： bedaquiline | drug-induced liver injury (DILI) | FAERS | linezolid | pretomanid | tuberculosis | drug‐induced liver injury (DILI)

4008-161-200 800-990-8900

国家科技图书文献中心

关键词： DNA methylation; antituberculosis drug‐induced liver injury; drug‐induced liver injury

摘要：ObjectiveDrug-induced liver injury (DILI) is a | is clinically challenging, and liver injury can be | more severe liver injury and worse outcomes after | severe leading to liver failure, death, or liver | transplantation. Patients with underlying chronic liver diseases

关键词： acute-on-chronic liver failure | chronic liver disease | drug-induced liver injury | acute‐on‐chronic liver failure | drug‐induced liver injury

摘要： induced liver injury (DILI). The aim of this study was | % were jaundiced; and all had hepatocellular injury | sclerosis (MS). Liver biopsies in 7 cases revealed mild | ).ConclusionMP DILI is characterised by hepatocellular injury | Background and AimsShort courses of

关键词： drug induced liver injury | HLA genotype associations | methylprednisolone | multiple sclerosis

关键词： drug‐induced liver injury | hepatotoxicity | herbal and dietary supplements

摘要： difficult to distinguish between drug‐induced liver injury | induced liver injury, SILI). The aims of the study were | (DILI) and liver injury associated with sepsis (sepsis | with a HC pattern of liver injury favours the | with markers of more pronounced liver injury.

关键词： drug‐induced liver injury | hepatotoxicity | liver injury | sepsis

摘要： liver injury (DILI) risk assessment in the preclinical | . While liver test abnormalities are rather common in | not well understood, complicating the drug-induced | mechanisms of liver toxicity, are described here to the | oncology, where standard liver signals during drug

关键词： CAR‐T cell therapy | covalent tyrosine kinase inhibitors | cTKI | DILI | drug‐induced liver injury | ILICI | immune checkpoint inhibitors | CAR-T cell therapy | drug-induced liver injury

摘要：‐induced liver injury (DILI) is a challenging task due to | imaging tests to exclude other causes of liver injury | Abstract The diagnosis of idiosyncratic drug | the lack of specific features or definitive | diagnostic tools. A minimum of clinical and pharmacological

关键词： causality assessment methods | hepatotoxicity | idiosyncratic drug‐induced liver injury | RECAM | RUCAM | structured expert opinion

摘要：Abstract Drug-induced liver injury (DILI) is | an acute liver injury that poses a significant | injury and liver regeneration stages of DILI. This | progress into chronic DILI or even lead to liver failure | hepatocytes, the immune responses and liver inflammation

关键词： Drug-induced liver injury | Innate immune regulation | Inflammation resolution | Liver regeneration

摘要： the early diagnosis of drug-induced liver injury | successfully applied in imaging of Cys in drug-induced liver | injury in vivo. The research demonstrated that HPXI-6C | Cysteine (Cys) is involved in many | physiological processes. It's challenging to detect Cys

关键词： Fluorescent probe | Cysteine | Fluorescent imaging | Drug-induced liver injury

摘要： liver injury (DILI) with the BPaL regimen compared to | study investigated the association of drug-induced | Aims: The emergence of drug-resistant | tuberculosis has necessitated novel treatments like the | pretomanid, bedaquiline and linezolid (BPaL) regimen. This

关键词： bedaquiline | drug-induced liver injury (DILI) | FAERS | linezolid | pretomanid | tuberculosis | drug‐induced liver injury (DILI)

4008-161-200 800-990-8900

国家科技图书文献中心

摘要：ObjectiveDrug-induced* liver injury (DILI) is a* | is clinically challenging, and liver* injury can be* | more severe liver* injury and worse outcomes after* | severe leading to liver failure, death, or liver | transplantation. Patients with underlying chronic liver* diseases*

摘要： induced liver injury (DILI). The aim of this study was | % were jaundiced; and all had hepatocellular injury | sclerosis (MS). Liver* biopsies in 7 cases revealed mild* | ).ConclusionMP DILI is characterised by hepatocellular injury | Background and AimsShort courses of

摘要： difficult to distinguish between drug‐induced liver injury | induced liver injury, SILI). The aims of the study were | (DILI) and liver* injury associated with sepsis (sepsis* | with a HC pattern of liver* injury favours the* | with markers of more pronounced liver* injury.*

摘要： liver injury (DILI) risk assessment in the preclinical | . While liver* test abnormalities are rather common in* | not well understood, complicating the drug-induced | mechanisms of liver* toxicity, are described here to the* | oncology, where standard liver* signals during drug*

摘要：‐induced* liver injury (DILI) is a challenging task due to* | imaging tests to exclude other causes of liver injury | Abstract The diagnosis of idiosyncratic drug | the lack of specific features or definitive | diagnostic tools. A minimum of clinical and pharmacological

摘要：Abstract Drug-induced* liver injury (DILI) is* | an acute liver* injury that poses a significant* | injury and liver regeneration stages of DILI. This | progress into chronic DILI or even lead to liver* failure* | hepatocytes, the immune responses and liver* inflammation*