NSTL国家科技图书文献中心

1. Glycoprotein nonmetastatic melanoma protein B is regulated by hepatic peroxisome proliferator-activated receptor γ in liver steatosis NSTL国家科技图书文献中心

Aibara, Daisuke | Matsusue, Kimihiko - 《Cellular Signalling》 - 2025,130 - 共10页

摘要： microarray database was used to examine the gene* expression* | leptindeficient (ob/ob) mice, as well as in patients with non | knockout (PPAR gamma LKO) in ob/ob mice. Similarly | . Transcriptomic analysis of the human* liver samples revealed* | Hepatic glycoprotein nonmetastatic melanoma

关键词： Gpnmb | PPAR gamma | Non-alcoholic fatty liver disease | Liver steatosis | Nuclear receptor

2. Glucose regulation of adipose tissue browning by CBP/p300- and HDAC3-mediated reversible acetylation of CREBZF NSTL国家科技图书文献中心

Aoyuan Cui | Yaqian Xue ... - 《Proceedings of the National Academy of Sciences of the United States of America.》 - 2024,121(16) - e2318935121～e2318935121 - 共6页

摘要：. Glucose induces CREBZF in human* white adipose tissue* | thermogenic gene* expression, browning of iWAT, and adaptive* | thermogenic gene* expression. Expression levels of CREBZF are* | negatively correlated with UCP1 in human* adipose tissues* | and increased in WAT of obese ob/ob mice, which may

关键词： CREBZF | adipose tissue | glucose-sensing pathway | reversible acetylation | thermogenesis.

3. Impact of diesel particulate matter on the olfactory bulb of mice: insights from behavioral, histological, and molecular assessments NSTL国家科技图书文献中心

Lee, Jeongmin | Weerasinghe-Mudiyans...... - 《Molecular & Cellular Toxicology》 - 2024,20(3) - 735～745 - 共11页

摘要： pathway. Although extensive human* epidemiological and* | , histological, and molecular changes in the olfactory bulb (OB | genes (DEGs) in the OB that met the criteria of fold | downregulated. Gene* ontology-based functional analysis* | in gene* expression and the presence of mild*

关键词： Diesel particulate matter | Differentially expressed genes | Microglia | Olfactory bulb | Olfactory dysfunction

4. A conserved molecular logic for neurogenesis to gliogenesis switch in the cerebral cortex NSTL国家科技图书文献中心

Xiaoyi G. Liang | Kendy Hoang ... - 《Proceedings of the National Academy of Sciences of the United States of America.》 - 2024,121(20) - e2321711121～e2321711121 - 共6页

摘要： the olfactory bulb (OB). Understanding the | oligodendrocytes and OB interneurons. During this process | gliogenesis and OB interneuron neurogenesis in the cortex | , prevent precocious expression of Olig2, a gene* essential* | conserved between the mouse and human. Our study reveals

关键词： gliogenesis | neurogenesis | lineage switch | enhancer | Olig2

5. Skeletal muscle TET3 promotes insulin resistance through destabilisation of PGC-1α NSTL国家科技图书文献中心

Liu B | Xie D ... - 《Diabetologia: Clinical and Experimental Diabetes and Metabolism = Organ of the European Association for the Study of Diabetes (EASD)》 - 2024,67(4) - 724～737 - 共14页

摘要： genetically induced (ob/ob) obesity/diabetes. Muscle | diabetes and in HFD-fed and ob/ob mice compared with | levels (~25–60%) in HFD-fed or ob/ob mice compared with | their control counterparts. In human* and murine* | availability: Sequences are available from the Gene

关键词： Diabetes | Insulin resistance | Mitochondria | Obesity | PGC-1α | Skeletal muscle | TET3

Jakhotia, Sneha | Kavvuri, Rajesh ... - 《International journal of obesity》 - 2024,48(8) - 1080～1091 - 共12页 - 被引量：1

摘要： unexplored.MethodsIn this study, we employed spontaneous WNIN/Ob rats | models. Gene* expression analysis in the rodents was* | compared with human* subjects by data mining using* | database.ResultsWNIN/Ob rats were presented with proteinuria and | BackgroundThe prevalence of obesity is

关键词： BODY-MASS INDEX | PARIETAL EPITHELIAL-CELLS | DRASH SYNDROME | GLOMERULOSCLEROSIS | RAT | MODEL | STAGE | NEPHROPATHY | PROGRESSION | MECHANISMS

7. Chemical shift assignments of wildtype human leptin NSTL国家科技图书文献中心

Fan Xiao | Qin Ruiqi ... - 《Biomolecular NMR assignments》 - 2023,17(2) - 265～268 - 共4页

摘要： 16-kDa hormone encoded by the ob/ob gene. It serves | resonance assignments of wild-type human* leptin as a basis* | Abstract Leptin is an adipose tissue-expressed | a crucial role in regulating diverse physiological | processes, including body weight control, energy

关键词： NMR | Assignment | Leptin | Signaling

8. Dysregulation of Lipid Droplet Protein Expression in Adipose Tissues and Association with Metabolic Risk Factors in Adult Females with Obesity and Type 2 Diabetes NSTL国家科技图书文献中心

Park, Chan Yoon | Kim, Donguk ... - 《The Journal of Nutrition: Official Organ of the American Institute of Nutrition》 - 2023,153(3) - 691～702 - 共12页 - 被引量：5

摘要：), nondiabetic obese (OB; BMI > 30 kg/m2; n = 38), and diabetic | obese (OB/DM; BMI > 30 kg/m2, fasting glucose >= 126 | metabolic improvement agents on LD protein gene | expressions were investigated in human* adipocytes.Results* | and higher in VAT in OB subjects relative to NW

关键词： lipid droplet protein | obesity | type 2 diabetes | PLIN1 | CIDEA | CIDEC | ALPHA-INDUCED LIPOLYSIS | GENE-EXPRESSION | ENDOPLASMIC-RETICULUM | PERILIPIN EXPRESSION...

9. Protective impact of nicotinamide mononucleotide (NMN) and platelet-rich fibrin (PRF) on replicative and radiation-induced senescence of human osteoblasts NSTL国家科技图书文献中心

Hakim S.G. | von der Gracht A.... - 《Journal of Cranio-Maxillofacial Surgery》 - 2023,51(7/8) - 497～507 - 共11页

摘要：/replicative senescence and radiation in human* osteoblasts* | -galactosidase staining (SA β-gal), and senescence-related gene | that replicative OB aging follows a different pattern | elevation after spontaneous replicative aging of OB (agiT1 | ? 2023The aim of this study was to investigate

关键词： NMN | Osteoblasts | PRF | Radiation | RT2 profiler PCR array | Senescence | β-galactosidase

10. Phyllanthus emblica L. extract alleviates leptin resistance and lipid accumulation by inhibiting methylglyoxal production NSTL国家科技图书文献中心

Huang Y.-N. | Chen S.-Y.... - 《Food Bioscience》 - 2023,53 - 1～12 - 共12页

摘要： and activity or indirectly affect leptin gene* and* | receptors (Ob-Rb and HuB219.1), and this was accompanied | -associated signaling cascade (SREBP-1/ACC/FAS) gene | /CPT-1 pathway in human* HepG2 liver cells exposed to* | © 2023 Elsevier LtdIncreasing leptin

摘要： microarray database was used to examine the gene* expression* | leptindeficient (ob/ob) mice, as well as in patients with non | knockout (PPAR gamma LKO) in ob/ob mice. Similarly | . Transcriptomic analysis of the human* liver samples revealed* | Hepatic glycoprotein nonmetastatic melanoma

关键词： Gpnmb | PPAR gamma | Non-alcoholic fatty liver disease | Liver steatosis | Nuclear receptor

关键词： CREBZF | adipose tissue | glucose-sensing pathway | reversible acetylation | thermogenesis.

摘要： pathway. Although extensive human* epidemiological and* | , histological, and molecular changes in the olfactory bulb (OB | genes (DEGs) in the OB that met the criteria of fold | downregulated. Gene* ontology-based functional analysis* | in gene* expression and the presence of mild*

关键词： Diesel particulate matter | Differentially expressed genes | Microglia | Olfactory bulb | Olfactory dysfunction

摘要： the olfactory bulb (OB). Understanding the | oligodendrocytes and OB interneurons. During this process | gliogenesis and OB interneuron neurogenesis in the cortex | , prevent precocious expression of Olig2, a gene* essential* | conserved between the mouse and human. Our study reveals

关键词： gliogenesis | neurogenesis | lineage switch | enhancer | Olig2

摘要： genetically induced (ob/ob) obesity/diabetes. Muscle | diabetes and in HFD-fed and ob/ob mice compared with | levels (~25–60%) in HFD-fed or ob/ob mice compared with | their control counterparts. In human* and murine* | availability: Sequences are available from the Gene

关键词： Diabetes | Insulin resistance | Mitochondria | Obesity | PGC-1α | Skeletal muscle | TET3

摘要： unexplored.MethodsIn this study, we employed spontaneous WNIN/Ob rats | models. Gene* expression analysis in the rodents was* | compared with human* subjects by data mining using* | database.ResultsWNIN/Ob rats were presented with proteinuria and | BackgroundThe prevalence of obesity is

关键词： BODY-MASS INDEX | PARIETAL EPITHELIAL-CELLS | DRASH SYNDROME | GLOMERULOSCLEROSIS | RAT | MODEL | STAGE | NEPHROPATHY | PROGRESSION | MECHANISMS

摘要： 16-kDa hormone encoded by the ob/ob gene. It serves | resonance assignments of wild-type human* leptin as a basis* | Abstract Leptin is an adipose tissue-expressed | a crucial role in regulating diverse physiological | processes, including body weight control, energy

关键词： NMR | Assignment | Leptin | Signaling

摘要：), nondiabetic obese (OB; BMI > 30 kg/m2; n = 38), and diabetic | obese (OB/DM; BMI > 30 kg/m2, fasting glucose >= 126 | metabolic improvement agents on LD protein gene | expressions were investigated in human* adipocytes.Results* | and higher in VAT in OB subjects relative to NW

关键词： lipid droplet protein | obesity | type 2 diabetes | PLIN1 | CIDEA | CIDEC | ALPHA-INDUCED LIPOLYSIS | GENE-EXPRESSION | ENDOPLASMIC-RETICULUM | PERILIPIN EXPRESSION...

关键词： NMN | Osteoblasts | PRF | Radiation | RT2 profiler PCR array | Senescence | β-galactosidase

摘要： and activity or indirectly affect leptin gene* and* | receptors (Ob-Rb and HuB219.1), and this was accompanied | -associated signaling cascade (SREBP-1/ACC/FAS) gene | /CPT-1 pathway in human* HepG2 liver cells exposed to* | © 2023 Elsevier LtdIncreasing leptin

关键词： Free fatty acid | Leptin resistance | Methylglyoxal | Obesity | Phyllanthus emblica

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： microarray database was used to examine the gene expression | leptindeficient (ob/ob) mice, as well as in patients with non | knockout (PPAR gamma LKO) in ob/ob mice. Similarly | . Transcriptomic analysis of the human liver samples revealed | Hepatic glycoprotein nonmetastatic melanoma

关键词： Gpnmb | PPAR gamma | Non-alcoholic fatty liver disease | Liver steatosis | Nuclear receptor

关键词： CREBZF | adipose tissue | glucose-sensing pathway | reversible acetylation | thermogenesis.

摘要： pathway. Although extensive human epidemiological and | , histological, and molecular changes in the olfactory bulb (OB | genes (DEGs) in the OB that met the criteria of fold | downregulated. Gene ontology-based functional analysis | in gene expression and the presence of mild

关键词： Diesel particulate matter | Differentially expressed genes | Microglia | Olfactory bulb | Olfactory dysfunction

摘要： the olfactory bulb (OB). Understanding the | oligodendrocytes and OB interneurons. During this process | gliogenesis and OB interneuron neurogenesis in the cortex | , prevent precocious expression of Olig2, a gene essential | conserved between the mouse and human. Our study reveals

关键词： gliogenesis | neurogenesis | lineage switch | enhancer | Olig2

摘要： genetically induced (ob/ob) obesity/diabetes. Muscle | diabetes and in HFD-fed and ob/ob mice compared with | levels (~25–60%) in HFD-fed or ob/ob mice compared with | their control counterparts. In human and murine | availability: Sequences are available from the Gene

关键词： Diabetes | Insulin resistance | Mitochondria | Obesity | PGC-1α | Skeletal muscle | TET3

摘要： unexplored.MethodsIn this study, we employed spontaneous WNIN/Ob rats | models. Gene expression analysis in the rodents was | compared with human subjects by data mining using | database.ResultsWNIN/Ob rats were presented with proteinuria and | BackgroundThe prevalence of obesity is

关键词： BODY-MASS INDEX | PARIETAL EPITHELIAL-CELLS | DRASH SYNDROME | GLOMERULOSCLEROSIS | RAT | MODEL | STAGE | NEPHROPATHY | PROGRESSION | MECHANISMS

摘要： 16-kDa hormone encoded by the ob/ob gene. It serves | resonance assignments of wild-type human leptin as a basis | Abstract Leptin is an adipose tissue-expressed | a crucial role in regulating diverse physiological | processes, including body weight control, energy

关键词： NMR | Assignment | Leptin | Signaling

摘要：), nondiabetic obese (OB; BMI > 30 kg/m2; n = 38), and diabetic | obese (OB/DM; BMI > 30 kg/m2, fasting glucose >= 126 | metabolic improvement agents on LD protein gene | expressions were investigated in human adipocytes.Results | and higher in VAT in OB subjects relative to NW

关键词： lipid droplet protein | obesity | type 2 diabetes | PLIN1 | CIDEA | CIDEC | ALPHA-INDUCED LIPOLYSIS | GENE-EXPRESSION | ENDOPLASMIC-RETICULUM | PERILIPIN EXPRESSION...

关键词： NMN | Osteoblasts | PRF | Radiation | RT2 profiler PCR array | Senescence | β-galactosidase

摘要： and activity or indirectly affect leptin gene and | receptors (Ob-Rb and HuB219.1), and this was accompanied | -associated signaling cascade (SREBP-1/ACC/FAS) gene | /CPT-1 pathway in human HepG2 liver cells exposed to | © 2023 Elsevier LtdIncreasing leptin

关键词： Free fatty acid | Leptin resistance | Methylglyoxal | Obesity | Phyllanthus emblica

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： pathway. Although extensive human* epidemiological and* | , histological, and molecular changes in the olfactory bulb (OB | genes (DEGs) in the OB that met the criteria of fold | downregulated. Gene* ontology-based functional analysis* | in gene* expression and the presence of mild*

摘要： the olfactory bulb (OB). Understanding the | oligodendrocytes and OB interneurons. During this process | gliogenesis and OB interneuron neurogenesis in the cortex | , prevent precocious expression of Olig2, a gene* essential* | conserved between the mouse and human. Our study reveals

摘要： genetically induced (ob/ob) obesity/diabetes. Muscle | diabetes and in HFD-fed and ob/ob mice compared with | levels (~25–60%) in HFD-fed or ob/ob mice compared with | their control counterparts. In human* and murine* | availability: Sequences are available from the Gene

摘要： unexplored.MethodsIn this study, we employed spontaneous WNIN/Ob rats | models. Gene* expression analysis in the rodents was* | compared with human* subjects by data mining using* | database.ResultsWNIN/Ob rats were presented with proteinuria and | BackgroundThe prevalence of obesity is

摘要： 16-kDa hormone encoded by the ob/ob gene. It serves | resonance assignments of wild-type human* leptin as a basis* | Abstract Leptin is an adipose tissue-expressed | a crucial role in regulating diverse physiological | processes, including body weight control, energy

摘要：), nondiabetic obese (OB; BMI > 30 kg/m2; n = 38), and diabetic | obese (OB/DM; BMI > 30 kg/m2, fasting glucose >= 126 | metabolic improvement agents on LD protein gene | expressions were investigated in human* adipocytes.Results* | and higher in VAT in OB subjects relative to NW

摘要： and activity or indirectly affect leptin gene* and* | receptors (Ob-Rb and HuB219.1), and this was accompanied | -associated signaling cascade (SREBP-1/ACC/FAS) gene | /CPT-1 pathway in human* HepG2 liver cells exposed to* | © 2023 Elsevier LtdIncreasing leptin