全部 |
  • 全部
  • 题名
  • 作者
  • 机构
  • 关键词
  • NSTL主题词
  • 摘要
检索 二次检索 AI检索
外文文献 中文文献
筛选条件:

1. Efficacy and Safety of Fibroblast Growth Factor 21 Analogues for Metabolic Dysfunction-Associated Steatohepatitis: A Systematic Review and Meta-Analysis NSTL国家科技图书文献中心

Fabiana,Dolovitsch d... |  Samira Mohamad,Khali...... -  《Annals of Nutrition & Metabolism》 - 2025,81(1) - 51~60 - 共10页

摘要: factor 21 (FGF21) analogues may benefit patients with | Abstract Introduction: Fibroblast growth |  FGF21 analogues versus placebo for treating patients | ). Results: We included 7 RCTs (886 patients). FGF21 |  stage of fibrosis showed that FGF21 analogues improved
关键词: Metabolic-dysfunction-associated steatohepatitis |  Metabolic dysfunction-associated steatohepatitis |  Fibrosis |  Efficacy |  FGF21 analogues

2. FGF21 Analogues in Patients With Metabolic Diseases: Systematic Review and Meta-Analysis of Randomised Controlled Trials NSTL国家科技图书文献中心

Theofilis, Panagioti... |  Oikonomou, Evangelos... -  《Liver international》 - 2025,45(3) - e70016~e70016 - 共11页

摘要: assess the effect of fibroblast growth factor- 21 |  (FGF21) analogues on hepatic steatosis, inflammation |  controlled trials (RCTs) assessing the effect of FGF21 | . Results: Treatment with FGF21 analogues was associated | , 2.59, p = 0.002). FGF21 analogues significantly
关键词: fibroblast growth factor 21 |  hepatic fat fraction |  hepatic fibrosis |  steatohepatitis

3. Engineered extracellular vesicles with surface FGF21 and enclosed miR-223 for treating metabolic dysfunction-associated steatohepatitis NSTL国家科技图书文献中心

Cho, Hanchae |  Ju, Hyunji... -  《Biomaterials》 - 2025,321 - 共15页

摘要: factor 21 (FGF21) on their surface and encapsulate miR | , EVs were engineered to display fibroblast growth | , using an FGF21-blocking antibody or miR-223 inhibitor | , confirming the essential roles of FGF21 and miR-223 in |  conventional FGF21 treatment. Collectively, 223/F-EVs convey
关键词: Metabolic dysfunction-associated steatohepatitis |  Extracellular vesicles |  Combination therapies |  Fibroblast growth factor 21 |  Micro-RNA

4. Adipokine/hepatokines profiling of fatty liver in adolescents and young adults: cross-sectional and prospective analyses of the BCAMS study NSTL国家科技图书文献中心

Yi, Xinghao |  Han, Lanwen... -  《Hepatology international》 - 2025,19(1) - 143~155 - 共13页

摘要: adiponectin, leptin, fibroblast growth factor 21 (FGF21 |  prospective analyses identified increased RBP4, FGF21 | , including leptin/adiponectin, FGF21/adiponectin, and RBP4 | , FGF21 and leptin, alongside lower adiponectin, could | Objective The underlying connections between
关键词: Leptin |  Adiponectin |  Retinol-binding protein 4 |  Fibroblast growth factor 21 |  Angiopoietin-like protein 8 |  NAFLD |  Young population

5. Treating metabolic dysfunction‐associated steatohepatitis: The fat‐trimming FGF21 approach NSTL国家科技图书文献中心

Xiaokun Li |  Zhiheng Rao... -  《Obesity reviews :》 - 2025,26(3) - e13861~e13861 - 共14页

摘要:, pharmacological FGF21 acts as a potent catabolic factor to |  trials, including analogs of FGF21 and agonists of the |  in patients with MASH. Endocrine FGF21 plays a |  several FGF21 mimetics. We compare these outcomes with | Summary Metabolic dysfunction‐associated
关键词: fibroblast growth factor 21 (FGF21) |  lipid metabolism |  metabolic dysfunction‐associated steatohepatitis (MASH) |  protein therapeutics

6. Hepatic lipogenesis marked by GCKR‐modulated triglycerides increases serum FGF21 in children/teens with obesity NSTL国家科技图书文献中心

Claudio Maffeis |  Anita Morandi... -  《Diabetes, obesity & metabolism.》 - 2025,27(2) - 825~834 - 共10页

摘要:Abstract Aims Fibroblast growth factor 21 | ). The Pro446Leu variant increased FGF21 (β = +0.14, p |  associated with increased serum FGF21 in children |  (FGF21) decreases hepatic lipogenesis in animal models | , and FGF21 analogues decrease serum triglycerides (TG
关键词: insulin resistance |  lipid‐lowering therapy |  liver |  obesity care

7. Maternal exercise represses FGF21 via SIRT1 to improve the phenotypic transformation of vascular smooth muscle in hypertensive offspring NSTL国家科技图书文献中心

Shan, Meiling |  Qiu, Fang... -  《Hypertension research》 - 2025,48(1) - 353~365 - 共13页

摘要: elevated blood pressure and fibroblast growth factor 21 |  (FGF21) levels. It remains unclear whether maternal |  in hypertensive offspring by regulating FGF21 and |  acetylation) in the promoter region of the FGF21 gene. This |  downregulation of FGF21 in the MAs of hypertensive fetuses
关键词: Maternal exercise |  Hypertension |  Epigenetic modification |  FGF21 |  Phenotype switching

8. The role of the glucagon-FGF21 axis in improving beta cell function during glucose intolerance and SGLT2 inhibition NSTL国家科技图书文献中心

Moreno-Lopez, Maria |  Louvet, Isaline... -  《Diabetes, obesity & metabolism.》 - 2025,27(2) - 885~898 - 共14页

摘要: liver, Fibroblast Growth Factor 21 (FGF21) is also |  glucagon-FGF21 interaction in the metabolic benefits of | ).Methods: FGF21, FGF1R, and beta-klotho expression in |  recombinant FGF21 (rFGF21) on islets from donors with |  glucagon-FGF21 axis in the benefits of SGLT2i, we used WT
关键词: FGF21 |  glucagon |  glucose intolerance |  human islets |  SGLT2 inhibition |  type 2 diabetes

9. Inflammatory proteins and hidradenitis suppurativa: Insights from genetic correlation and Mendelian randomization NSTL国家科技图书文献中心

Luo, Hui |  Chen, Yang... -  《The Journal of dermatology》 - 2025,52(3) - 481~492 - 共12页

摘要: Fibroblast growth factor 21 (FGF-21), stem cell factor, and |  inhibitory factor (LIF), LIF receptor, and Thymic stromal | Previous research has highlighted a |  significant association between inflammatory proteins and |  the development and progression of hidradenitis
关键词: causal relationship |  hidradenitis suppurativa |  inflammatory proteins |  linkage disequilibrium score regression |  Mendelian randomization

10. Human milk feeding practices and serum immune profiles of one-year-old infants in the CHILD birth cohort study NSTL国家科技图书文献中心

Ames, Spencer R. |  Lotoski, Larisa C.... -  《The American Journal of Clinical Nutrition》 - 2025,121(1) - 60~73 - 共14页

摘要: levels of serum fibroblast growth factor 21 (FGF-21 | Background: Breastfeeding and human milk |  consumption are associated with immune system development | ; however, the underlying mechanisms and the impact of |  different infant feeding practices are unclear. Objectives
关键词: breastfeeding |  lactation |  human milk |  breast milk |  infant feeding practices |  early life nutrition |  immune system development |  serum proteomics |  developmental origins of health and disease |  CHILD cohort study
检索条件Fibroblast Growth Factor 21
  • 检索词扩展

NSTL主题词

  • NSTL学科导航