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1. FOXP3+ Macrophage-Derived Amphiregulin Promotes White Matter Repair of Experimental Autoimmune Encephalomyelitis NSTL国家科技图书文献中心

Shilin Wu |  Shishi Shen... -  《The FASEB Journal》 - 2025,39(11) - e70719~e70719 - 共17页

摘要: FOXP3 signaling, which induces a pro-regenerative |  Foxp3 conditional knockout mice and show that FOXP3 |  suggest that FOXP3+ macrophages could serve as a | Multiple sclerosis (MS) is characterized by |  episodes of inflammatory demyelination followed by
关键词: FOXP3; amphiregulin; differentiation; experimental autoimmune encephalomyelitis; macrophages

2. Electroacupuncture Promotes the Generation of Intestinal Treg Cells After Ischemic Stroke by Foxp3 Acetylation Regulation NSTL国家科技图书文献中心

Chen, Yonglin |  Ouyang, Ling... -  《Molecular Neurobiology》 - 2025,62(3) - 3697~3711 - 共15页

摘要: activity (HDAC). Additionally, acetylated Foxp3 protein |  SCFA-mediated Foxp3 acetylation in Treg cells. | Electroacupuncture (EA) has been shown to |  ameliorate brain injury and protect against intestinal |  injury after ischemic stroke. These protective effects
关键词: Electroacupuncture |  Ischemic Stroke |  Short-chain Fatty Acids |  Foxp3 |  Treg

3. Resveratrol-A Herbal Immunomodulator, Ameliorates Experimental Autoimmune Myasthenia Gravis by Regulating the Foxo1-Foxp3 Pathway NSTL国家科技图书文献中心

Cheng, Heyun |  Shan, Yunan... -  《Journal of biochemical and molecular toxicology》 - 2025,39(5) - e70265~e70265 - 共18页

摘要: identified the Foxo1/Foxp3 pathway as integral to RES's |  and Foxp3 expression levels were elevated in the |  indicated decreased Foxp3 expression following Foxo1 |  immune cells by affecting the Foxo1/Foxp3 pathway. | Resveratrol (RES), extracted from traditional
关键词: dendritic cell |  experimental autoimmune myasthenia gravis |  Foxo1 |  Foxp3 |  network pharmacology |  resveratrol |  Treg

4. Biochemical investigation of FOXP3 genetic polymorphism and its association with biochemical parameters in pre-eclampsia patients NSTL国家科技图书文献中心

Akash, Muhammad Saji... |  Victor, Francis... -  《Naunyn-Schmiedeberg's Archives of Pharmacology》 - 2025,398(4) - 4583~4592 - 共10页

摘要: the association between FOXP3 gene polymorphism and |  between FOXP3 gene polymorphism (rs2232365) and the risk |  significant differences in FOXP3 gene polymorphism between |  pregnancy, led to an exploration of FOXP3 due to its |  from peripheral blood samples, and FOXP3 promoter
关键词: Pre-eclampsia |  Gene polymorphism |  Forkhead box P3 |  Immunosuppression |  Regulatory T cells

5. A splice of life: the discovery, function, and clinical implications of FOXP3 isoforms in autoimmune disease NSTL国家科技图书文献中心

Weinstein, Kristin N... |  Domeier, Phillip P.... -  《International immunology.》 - 2025,37(2) - 83~90 - 共8页

摘要: encoded transcription factor forkhead box P3 (FOXP3). In |  humans, multiple FOXP3 isoforms are generated through |  coding exons (FOXP3-FL) and a version lacking the |  second exon (FOXP3-Delta E2) are the predominant FOXP3 |  lacking either exon 7 (FOXP3-Delta E7) and both exons 2
关键词: IPEX syndrome |  regulatory T cells |  transcription factors

6. MAPK and STAT3 Inhibitors Modulate FoxP3 Expression and Regulatory T Cell Function NSTL国家科技图书文献中心

Nuria García-Díaz |  Ehsan Hajjar... -  《European journal of immunology.》 - 2025,55(2) - e202451225~e202451225 - 共12页

摘要: protein P3 (FoxP3) playing a crucial role in regulating |  microenvironment facilitating tumor growth. Thus, targeting FoxP3 |  downregulating FoxP3 expression in human primary T cells. We |  downregulating FoxP3 expression. To identify more potent |  reduce FoxP3 expression in a similar- or more potent
关键词: MAPK; STAT3; phenotypic drug screening; regulatory T cells; signal transduction

7. Negative Impact of High FOXP3 Status in Lymph Nodes of Esophageal Squamous Cell Carcinoma Patients NSTL国家科技图书文献中心

Nonaka, Yukiko |  Baba, Taisuke... -  《Anticancer Research》 - 2025,45(2) - 781~787 - 共7页

摘要:] and high FOXP3 status in PLNs (HR=4.29; 95%CI=1.06 |  prognostic factors. Furthermore, high FOXP3 status in PLNs | %CI=0.58-5.02). Conclusion: High FOXP3 status in | Background/Aim: Available data on the immune |  profiles of regional lymph nodes in individuals with
关键词: Esophageal cancer |  forkhead box protein 3 |  programmed cell death 1-ligand 1 |  lymph node

8. Methylation profile of CD247 and FOXP3 genes and frequency of certain HLA-DQ haplotypes in Celiac disease NSTL国家科技图书文献中心

Yildirim, Malik Ejde... |  Ataseven, Hilmi... -  《Clinics and research in hepatology and gastroenterology》 - 2025,49(4) - Article 102562~Article 102562 - 共7页

摘要: cell receptor complex and Forkhead box P3 (FOXP3) is |  of CD247 and FOXP3 genes, and to calculate the |  FOXP3 genes in samples were calculated using the |  contrary, FOXP3 had a significantly higher methylation | , whereas FOXP3 expression is downregulated in Celiac
关键词: CD247 |  FOXP3 |  Gene |  Methylation |  HLA haplotypes

9. FOXP3 Transcriptionally Activates Fatty Acid Scavenger Receptor CD36 in Tumour‐Induced Treg Cells NSTL国家科技图书文献中心

Subhanki Dhar |  Tania Sarkar... -  《Immunology》 - 2025,174(3) - 296~309 - 共14页

摘要: that it is necessary for Treg cell development. FOXP3 | ABSTRACT The host immune system is adapted in |  a variety of ways by tumour microenvironment and |  growing tumour interacts to promote immune escape. One |  of these adaptations is manipulating the metabolic
关键词: cancer |  CD36 |  metabolism |  Treg |  tumour microenvironment

10. Prophylactic Peanut Allergen Ara h 6 Sublingual Immunotherapy Drives Expansion of FoxP3 + Helios - Regulatory T Cells in the Absence of Allergen-Specific IgA NSTL国家科技图书文献中心

Larsen, Jeppe Madura |  Lundsgaard, Emma Alb...... -  《Immunology》 - 2025,174(3) - 340~348 - 共9页

摘要: cells within the conventional CD4+CD25+FoxP3+ Treg | Insights into the underlying immunological |  mechanisms of prophylactic sublingual immunotherapy (SLIT | ) may support the development of new strategies for |  improved prevention and treatment of food allergy. Here
关键词: immune response |  peanut allergy |  prophylaxis |  sublingual immunotherapy |  tissue response
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