NSTL国家科技图书文献中心

1. Identification of potential drug molecules against fibroblast growth factor receptor 3 (FGFR3) by multi-stage computational-biophysics correlate NSTL国家科技图书文献中心

Ahmad, Sajjad | Almanaa, Taghreed N.... - 《Journal of Biomolecular Structure and Dynamics》 - 2025,43(3) - 1240～1248 - 共9页

摘要：The fibroblast growth factor receptor 3 (FGFR3 | compounds against the active pocket of FGFR3. Compared to | bonds and van der Waals. The FGFR3* enzyme residues* | respect to FGFR3* with a mean root mean square deviation* | theoretical binding affinity for FGFR3* but experimental*

关键词： Fibroblast growth factor receptor 3 | BDC_24037121 | bdc_21200852 | bdc_21206757 | molecular dynamic simulation

2. Effect of miR-190a-3P on Chronic Diabetic Nephropathy by Regulating FGFR3 NSTL国家科技图书文献中心

Yuan Lin | Chaoyan Yin ... - 《Annals of Clinical and Laboratory Science》 - 2025,55(1) - 48～53 - 共6页

摘要： group (P<0.05). Meanwhile, FGFR3* protein levels in miR* | FGFR3 protein levels, contributing to the occurrence | diabetes. The FGF23/FGFR3-mediated signaling pathway is | through regulation of FGFR3* remains to be elucidated* | group, followed by analysis of miR-190a-3P and FGFR3

关键词： FGFR3; chronic diabetic nephropathy; miR-190a-3P.

3. FGFR3 Upregulates Interferon-Stimulated Genes Via the JAK1-STAT1 Signaling Pathway in HPV2 E2 Stable Expressing Keratinocytes NSTL国家科技图书文献中心

Guo, Qingqing | Wei, Xuanjin ... - 《Journal of Medical Virology》 - 2025,97(1) - e70147～e70147 - 共11页

摘要： fibroblast growth factor receptor 3 (FGFR3) to inhibit | FGFR3 in low-risk HPV infections remains elusive. Our | FGFR3 in HPV2 E2 stable expressing keratinocytes, we | that HPV2 E2 induced phosphorylation of FGFR3* could* | FGFR3 and HPV2 E2 in keratinocytes. In conclusion, our

关键词： antiviral immunity | FGFR3 | HPV infection | HPV2 E2 | JAK1-STAT1

4. FGFR3 :: TACC3 fusions in head and neck carcinomas: a study of nine cases highlighting phenotypic heterogeneity, frequent HPV association, and a morphologically distinct subset in favor of a putative entity NSTL国家科技图书文献中心

Agaimy, Abbas | Antonescu, Cristina ...... - 《Virchows Archiv》 - 2025,486(3) - 499～510 - 共12页

摘要：The FGFR3::TACC3 fusion has been reported in | of FGFR3::TACC3-positive head and neck carcinomas | describe nine FGFR3::TACC3 fusion-positive head and neck | FGFR3::TACC3 fusion in all cases. This series | harboring FGFR3::TACC3 fusions, which segregates into

关键词： Sinonasal | Gene fusions | RNA sequencing | FGFR | Targeted therapy | Tyrosine kinase inhibitor

5. Outcome-associated factors in a molecularly defined cohort of central neurocytoma NSTL国家科技图书文献中心

Maja,Krech | Amos,Muench ... - 《Acta Neuropathologica》 - 2025,149(1) - Article: 61～Article: 61 - 共16页

摘要： FGFR3 protein expression, was observed in 97% of cases | . Hypomethylation at the FGFR3* locus, accompanied by increased* | . Furthermore, FGFR3* represents a hallmark feature and* | Abstract Central neurocytomas (CN) are | intraventricular brain tumors predominantly occurring in young

关键词： Neurocytoma | DNA methylation profiling | Progression-free survival | FGFR3 | Radiotherapy

6. C-Type Natriuretic Peptide Analogs: Current and Future Therapeutic Applications NSTL国家科技图书文献中心

Despoina M.,Galetaki | Andrew,Dauber - 《Hormone research in p?diatrics》 - 2025,98(1) - 51～58 - 共8页

摘要： Messages: Alterations in the CNP/FGFR3* pathway can lead* | Abstract Background: Short stature is one of | the most common reasons for referral to a pediatric | endocrinologist that can be due to multitude of conditions | , including an ever-growing list of genetic etiologies

关键词： C-type natriuretic peptide | Growth | NPR | FGFR3

7. Efficacy of rituximab on antibody-positive small fiber neuropathy: A series of 5 cases NSTL国家科技图书文献中心

Chan, Amanda C. Y. | Shahana, R.... - 《Journal of Neuroimmunology》 - 2025,401 - 578559～578559 - 共6页

摘要：-FGFR3* and antiplexin D1 small fiber neuropathy (SFN* | titers towards TS-HDS, FGFR3* or plexin-D1 and received* | -plexin D1 and two for anti-FGFR3* antibodies* | Background & aims: We evaluated the efficacy | of rituximab in patients with anti-TS-HDS, anti

关键词： Small fiber neuropathy | Anti-FGFR3 antibody | Anti-TS-HDS antibody | Anti-CD20 monoclonal antibody | Anti-plexin D1 antibody

8. Cytokine Signature Unveils Subgroups of Patients With Immune-Mediated Sensory Neuronopathies NSTL国家科技图书文献中心

Christian P. Moritz | Yannick Tholance ... - 《Journal of the peripheral nervous system》 - 2025,30(1) - e70008～e70008 - 共9页

摘要： (such as anti-FGFR3* or anti-AGO antibodies), or* | -AGO antibodies, 48 had anti-FGFR3* antibodies, and 14* | -AGO or FGFR3* antibodies. Disease extent was measured* | -AGO or anti-FGFR3* antibodies, or association with an* | Background and aims: Immune-mediated sensory

关键词： anti‐cytokine antibodies; cytokine signature; cytokines; interleukins; sensory

9. Diagnostic and prognostic genomic aberrations in upper tract urothelial carcinoma can be identified in focal barbotage samples NSTL国家科技图书文献中心

Tomas Andri Axelsson | Filip Sydén ... - 《BJU international》 - 2025,135(5) - 792～801 - 共10页

摘要：%), FGFR3* (50%), KMT2D (42%), KDM6A (42%), ARID1A (39* | mutations in FGFR3* were common in grade 1 and 2 tumours* | with an FGFR3* mutation died during follow‐up. TP53* | Objectives To investigate whether genetic | analysis of focal barbotage samples obtained at

关键词： upper tract urothelial carcinoma | genomic profile | genetic aberrations | gene mutations | risk stratification | prognostic marker

10. FGFR Inhibition in Urothelial Carcinoma NSTL国家科技图书文献中心

Li, Roger | Linscott, Joshua ... - 《European urology》 - 2025,87(2) - 110～122 - 共13页 - 被引量：1

摘要： FGFR3 alterations ushered in the era of targeted | : Somatic FGFR3* alterations are found in up to 70% of* | cancer recurrence or progression. FGFR3-altered tumors | Background and objective: The 2024 US Food and | Drug Administration approval of erdafitinib for the

摘要：The fibroblast growth factor receptor 3 (FGFR3 | compounds against the active pocket of FGFR3. Compared to | bonds and van der Waals. The FGFR3* enzyme residues* | respect to FGFR3* with a mean root mean square deviation* | theoretical binding affinity for FGFR3* but experimental*

关键词： Fibroblast growth factor receptor 3 | BDC_24037121 | bdc_21200852 | bdc_21206757 | molecular dynamic simulation

摘要： group (P<0.05). Meanwhile, FGFR3* protein levels in miR* | FGFR3 protein levels, contributing to the occurrence | diabetes. The FGF23/FGFR3-mediated signaling pathway is | through regulation of FGFR3* remains to be elucidated* | group, followed by analysis of miR-190a-3P and FGFR3

关键词： FGFR3; chronic diabetic nephropathy; miR-190a-3P.

摘要： fibroblast growth factor receptor 3 (FGFR3) to inhibit | FGFR3 in low-risk HPV infections remains elusive. Our | FGFR3 in HPV2 E2 stable expressing keratinocytes, we | that HPV2 E2 induced phosphorylation of FGFR3* could* | FGFR3 and HPV2 E2 in keratinocytes. In conclusion, our

关键词： antiviral immunity | FGFR3 | HPV infection | HPV2 E2 | JAK1-STAT1

摘要：The FGFR3::TACC3 fusion has been reported in | of FGFR3::TACC3-positive head and neck carcinomas | describe nine FGFR3::TACC3 fusion-positive head and neck | FGFR3::TACC3 fusion in all cases. This series | harboring FGFR3::TACC3 fusions, which segregates into

关键词： Sinonasal | Gene fusions | RNA sequencing | FGFR | Targeted therapy | Tyrosine kinase inhibitor

摘要： FGFR3 protein expression, was observed in 97% of cases | . Hypomethylation at the FGFR3* locus, accompanied by increased* | . Furthermore, FGFR3* represents a hallmark feature and* | Abstract Central neurocytomas (CN) are | intraventricular brain tumors predominantly occurring in young

关键词： Neurocytoma | DNA methylation profiling | Progression-free survival | FGFR3 | Radiotherapy

摘要： Messages: Alterations in the CNP/FGFR3* pathway can lead* | Abstract Background: Short stature is one of | the most common reasons for referral to a pediatric | endocrinologist that can be due to multitude of conditions | , including an ever-growing list of genetic etiologies

关键词： C-type natriuretic peptide | Growth | NPR | FGFR3

摘要：-FGFR3* and antiplexin D1 small fiber neuropathy (SFN* | titers towards TS-HDS, FGFR3* or plexin-D1 and received* | -plexin D1 and two for anti-FGFR3* antibodies* | Background & aims: We evaluated the efficacy | of rituximab in patients with anti-TS-HDS, anti

关键词： Small fiber neuropathy | Anti-FGFR3 antibody | Anti-TS-HDS antibody | Anti-CD20 monoclonal antibody | Anti-plexin D1 antibody

摘要： (such as anti-FGFR3* or anti-AGO antibodies), or* | -AGO antibodies, 48 had anti-FGFR3* antibodies, and 14* | -AGO or FGFR3* antibodies. Disease extent was measured* | -AGO or anti-FGFR3* antibodies, or association with an* | Background and aims: Immune-mediated sensory

关键词： anti‐cytokine antibodies; cytokine signature; cytokines; interleukins; sensory

摘要：%), FGFR3* (50%), KMT2D (42%), KDM6A (42%), ARID1A (39* | mutations in FGFR3* were common in grade 1 and 2 tumours* | with an FGFR3* mutation died during follow‐up. TP53* | Objectives To investigate whether genetic | analysis of focal barbotage samples obtained at

关键词： upper tract urothelial carcinoma | genomic profile | genetic aberrations | gene mutations | risk stratification | prognostic marker

摘要： FGFR3 alterations ushered in the era of targeted | : Somatic FGFR3* alterations are found in up to 70% of* | cancer recurrence or progression. FGFR3-altered tumors | Background and objective: The 2024 US Food and | Drug Administration approval of erdafitinib for the

关键词： Urothelial cancer | Precision oncology | FGFR inhibitor | Immunotherapy

4008-161-200 800-990-8900

国家科技图书文献中心

摘要：The fibroblast growth factor receptor 3 (FGFR3 | compounds against the active pocket of FGFR3. Compared to | bonds and van der Waals. The FGFR3 enzyme residues | respect to FGFR3 with a mean root mean square deviation | theoretical binding affinity for FGFR3 but experimental

关键词： Fibroblast growth factor receptor 3 | BDC_24037121 | bdc_21200852 | bdc_21206757 | molecular dynamic simulation

摘要： group (P<0.05). Meanwhile, FGFR3 protein levels in miR | FGFR3 protein levels, contributing to the occurrence | diabetes. The FGF23/FGFR3-mediated signaling pathway is | through regulation of FGFR3 remains to be elucidated | group, followed by analysis of miR-190a-3P and FGFR3

关键词： FGFR3; chronic diabetic nephropathy; miR-190a-3P.

摘要： fibroblast growth factor receptor 3 (FGFR3) to inhibit | FGFR3 in low-risk HPV infections remains elusive. Our | FGFR3 in HPV2 E2 stable expressing keratinocytes, we | that HPV2 E2 induced phosphorylation of FGFR3 could | FGFR3 and HPV2 E2 in keratinocytes. In conclusion, our

关键词： antiviral immunity | FGFR3 | HPV infection | HPV2 E2 | JAK1-STAT1

摘要：The FGFR3::TACC3 fusion has been reported in | of FGFR3::TACC3-positive head and neck carcinomas | describe nine FGFR3::TACC3 fusion-positive head and neck | FGFR3::TACC3 fusion in all cases. This series | harboring FGFR3::TACC3 fusions, which segregates into

关键词： Sinonasal | Gene fusions | RNA sequencing | FGFR | Targeted therapy | Tyrosine kinase inhibitor

摘要： FGFR3 protein expression, was observed in 97% of cases | . Hypomethylation at the FGFR3 locus, accompanied by increased | . Furthermore, FGFR3 represents a hallmark feature and | Abstract Central neurocytomas (CN) are | intraventricular brain tumors predominantly occurring in young

关键词： Neurocytoma | DNA methylation profiling | Progression-free survival | FGFR3 | Radiotherapy

摘要： Messages: Alterations in the CNP/FGFR3 pathway can lead | Abstract Background: Short stature is one of | the most common reasons for referral to a pediatric | endocrinologist that can be due to multitude of conditions | , including an ever-growing list of genetic etiologies

关键词： C-type natriuretic peptide | Growth | NPR | FGFR3

摘要：-FGFR3 and antiplexin D1 small fiber neuropathy (SFN | titers towards TS-HDS, FGFR3 or plexin-D1 and received | -plexin D1 and two for anti-FGFR3 antibodies | Background & aims: We evaluated the efficacy | of rituximab in patients with anti-TS-HDS, anti

关键词： Small fiber neuropathy | Anti-FGFR3 antibody | Anti-TS-HDS antibody | Anti-CD20 monoclonal antibody | Anti-plexin D1 antibody

摘要： (such as anti-FGFR3 or anti-AGO antibodies), or | -AGO antibodies, 48 had anti-FGFR3 antibodies, and 14 | -AGO or FGFR3 antibodies. Disease extent was measured | -AGO or anti-FGFR3 antibodies, or association with an | Background and aims: Immune-mediated sensory

关键词： anti‐cytokine antibodies; cytokine signature; cytokines; interleukins; sensory

摘要：%), FGFR3 (50%), KMT2D (42%), KDM6A (42%), ARID1A (39 | mutations in FGFR3 were common in grade 1 and 2 tumours | with an FGFR3 mutation died during follow‐up. TP53 | Objectives To investigate whether genetic | analysis of focal barbotage samples obtained at

关键词： upper tract urothelial carcinoma | genomic profile | genetic aberrations | gene mutations | risk stratification | prognostic marker

摘要： FGFR3 alterations ushered in the era of targeted | : Somatic FGFR3 alterations are found in up to 70% of | cancer recurrence or progression. FGFR3-altered tumors | Background and objective: The 2024 US Food and | Drug Administration approval of erdafitinib for the

关键词： Urothelial cancer | Precision oncology | FGFR inhibitor | Immunotherapy

4008-161-200 800-990-8900

国家科技图书文献中心

摘要：The fibroblast growth factor receptor 3 (FGFR3 | compounds against the active pocket of FGFR3. Compared to | bonds and van der Waals. The FGFR3* enzyme residues* | respect to FGFR3* with a mean root mean square deviation* | theoretical binding affinity for FGFR3* but experimental*

摘要： group (P<0.05). Meanwhile, FGFR3* protein levels in miR* | FGFR3 protein levels, contributing to the occurrence | diabetes. The FGF23/FGFR3-mediated signaling pathway is | through regulation of FGFR3* remains to be elucidated* | group, followed by analysis of miR-190a-3P and FGFR3

摘要： fibroblast growth factor receptor 3 (FGFR3) to inhibit | FGFR3 in low-risk HPV infections remains elusive. Our | FGFR3 in HPV2 E2 stable expressing keratinocytes, we | that HPV2 E2 induced phosphorylation of FGFR3* could* | FGFR3 and HPV2 E2 in keratinocytes. In conclusion, our

摘要： FGFR3 protein expression, was observed in 97% of cases | . Hypomethylation at the FGFR3* locus, accompanied by increased* | . Furthermore, FGFR3* represents a hallmark feature and* | Abstract Central neurocytomas (CN) are | intraventricular brain tumors predominantly occurring in young

摘要： Messages: Alterations in the CNP/FGFR3* pathway can lead* | Abstract Background: Short stature is one of | the most common reasons for referral to a pediatric | endocrinologist that can be due to multitude of conditions | , including an ever-growing list of genetic etiologies

摘要：-FGFR3* and antiplexin D1 small fiber neuropathy (SFN* | titers towards TS-HDS, FGFR3* or plexin-D1 and received* | -plexin D1 and two for anti-FGFR3* antibodies* | Background & aims: We evaluated the efficacy | of rituximab in patients with anti-TS-HDS, anti

摘要： (such as anti-FGFR3* or anti-AGO antibodies), or* | -AGO antibodies, 48 had anti-FGFR3* antibodies, and 14* | -AGO or FGFR3* antibodies. Disease extent was measured* | -AGO or anti-FGFR3* antibodies, or association with an* | Background and aims: Immune-mediated sensory

摘要：%), FGFR3* (50%), KMT2D (42%), KDM6A (42%), ARID1A (39* | mutations in FGFR3* were common in grade 1 and 2 tumours* | with an FGFR3* mutation died during follow‐up. TP53* | Objectives To investigate whether genetic | analysis of focal barbotage samples obtained at

摘要： FGFR3 alterations ushered in the era of targeted | : Somatic FGFR3* alterations are found in up to 70% of* | cancer recurrence or progression. FGFR3-altered tumors | Background and objective: The 2024 US Food and | Drug Administration approval of erdafitinib for the