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1. Characteristics of the MicroRNA-Processing Enzymes in Melanocytic Skin Lesions: Dicer and DGCR8 Are Potential Biomarkers for Primary Cutaneous Melanomas NSTL国家科技图书文献中心

Schafer, Fabiola |  Bellolio, Enrique... -  《Experimental dermatology.》 - 2025,34(5) - e70110~e70110 - 共8页

摘要: characterise the expression profile of Dicer, Drosha, DGCR8 |  = 0.000). For Drosha and PACT, only dysplastic nevi | Primary cutaneous melanoma (PCM) is an |  aggressive skin cancer. Its physiopathology is a challenge |  with heterogeneous pathways involved. As such
关键词: DGCR8 |  dicer |  melanoma |  microRNA-processing enzymes |  pathogenesis

2. Function analysis of RNase III in response to oxidative stress in Synechocystis sp. PCC 6803 NSTL国家科技图书文献中心

Zhang, Yihang |  Hu, Xinyu... -  《Microbiological Research》 - 2025,292 - 共12页

摘要:RNase III, a ubiquitously distributed |  this study, we explored the role of RNase III in |  highlights the role of RNase III in adapting to |  endonuclease, plays an important role in RNA processing and |  functions as a global regulator of gene expression. In
关键词: RNase III |  slr0346 |  Oxidative stress |  Transcriptome

3. Impact of a random TN5 mutation on endoglucanase secretion in ruminal cellulolytic Escherichia coli NSTL国家科技图书文献中心

Pang, Jian |  Zhang, Long... -  《Gene》 - 2025,933 - 148936~148936 - 共5页

摘要:, which encode RNC-ribonuclease III (RNC), LONprotease | Objective: Most protein secretion systems are |  found in gram-negative bacteria, but the mechanism of |  endoglucanase (BcsZ) secretion in Escherichia coli (E. coli | ) remains unclear. Methods: In this study, we used JBZ-DH5
关键词: Escherichia coli |  Transposon |  Mutant library |  BcsZ |  Secretion mechanism

4. Alternative driver pathways in peripheral nerve sheath tumors - including DICER1 and/or KRAS alterations NSTL国家科技图书文献中心

Chang, Hsin-Yi |  Saoud, Carla... -  《Journal of Pathology》 - 2025,265(3) - 372~384 - 共13页

摘要:, ribonuclease III (DICER1) mutations and sharing | DICER1-associated sarcoma is an emerging |  entity, defined by either somatic or germline dicer 1 |  characteristic morphologic features irrespective of the site of |  origin. In addition to the DICER1 driver mutation
关键词: peripheral nerve sheath tumor |  KRAS |  DICER1 |  ATRX |  TP53 |  MPNST |  methylation

5. Chemical shift assignments of DRB2 domains, a dsRNA binding protein in A. thaliana RNAi pathway NSTL国家科技图书文献中心

Upasana Rai |  Debadutta Patra... -  《Biomolecular NMR assignments》 - 2025,19(1) - 71~76 - 共6页

摘要: is primarily controlled by DCL1, an RNase III | In Arabidopsis thaliana, micro-RNA regulation |  enzyme, and its associated proteins. DCL1, together |  with DRB2, governs a specific group of miRNAs that |  induce the inhibition of target mRNA translation. DRB2
关键词: DRB2 |  micro-RNA pathway |  dsRBD |  RNAi |  A. thaliana |  Viral replication complex arrest

6. SFTSV NSs interacts with AGO2 to regulate the RNAi pathway for viral replication NSTL国家科技图书文献中心

Javaid, Nasir |  Jang, Tae-Won... -  《Journal of Virology》 - 2025,99(4) - e0220524~e0220524 - 共22页

摘要: between NSs and DICER, facilitated by the two RNase III | RNA interference (RNAi) is a |  posttranscriptional gene silencing mechanism acting as an antiviral |  defense in eukaryotes. During viral replication | , intermediate double-stranded RNAs are processed into virus
关键词: SFTSV |  nonstructural protein |  RNAi |  viral replication |  bunyavirus

7. Engineering a novel entomopathogenic strain Pseudomonas chlororaphis for efficient production of double-stranded RNAs and pest control NSTL国家科技图书文献中心

Xie, Mengmeng |  Wang, Qinghai... -  《Pest Management Science》 - 2025,81(6) - 3263~3272 - 共10页

摘要:. chlororaphis BM, through knocking out the RNase III gene and | BACKGROUND: RNA interference (RNAi)-based |  pesticides are emerging as the next generation of pest |  control solutions. We have previously identified |  Pseudomonas chlororaphis strain R3-3, which exhibits
关键词: RNA interference |  double-stranded RNA |  pest control |  pseudomonas chlororaphis |  Plagiodera versicolora |  Henosepilachna vigintioctopunctata |  double‐stranded RNA

8. Removing immunogenic double-stranded RNA impurities post in vitro transcription synthesis for mRNA therapeutics production: A review of chromatography strategies NSTL国家科技图书文献中心

Siew, Yin Yin |  Zhang, Wei -  《Journal of chromatography,A》 - 2025,1740 - 共17页 - 被引量:1

摘要: denaturation) and RNase III enzymatic purification strategies | Messenger RNA (mRNA) vaccines and therapeutics |  hold immense potential for a wide range of clinical |  applications. However, the in vitro transcription (IVT | ) process used to synthesize mRNA also results in the
关键词: Double-stranded RNA (dsRNA) removal |  mRNA purification |  In vitro transcription (IVT) |  Chromatography |  Enzyme

9. Enhancing pest control in pear orchards: Harnessing nanocarrier SPc for efficient delivery of emamectin benzoate and dslgl to safeguard beneficial insects NSTL国家科技图书文献中心

Li, Jianying |  Zhang, Dongyue... -  《Entomologia generalis》 - 2025,45(1) - 217~228 - 共12页

摘要: susceptibility to EB. By utilizing the pET30a-BL21-RNase III | Chemical control stands as a cornerstone in |  orchard pest management, yet concerns arise from |  prolonged usage including resistance development, non | -target organism risks, and environmental repercussions
关键词: Insecticide |  Lethal giant larvae (lgl) gene |  Grapholitha molesta |  Cacopsylla chinensis |  biopesticide

10. A capsidless (+)RNA yadokarivirus hosted by a dsRNA virus is infectious as particles, cDNA, and dsRNA NSTL国家科技图书文献中心

Fadli, Muhammad |  Hisano, Sakae... -  《Journal of Virology》 - 2025,99(3) - e02166-24~e02166-24 - 共20页

摘要: RNase III, but not with proteinase K, S1 nuclease, or | Capsidless yadokariviruses (members of the |  order Yadokarivirales) with (+)RNA genomes divert the |  capsid of their partner icosahedral double-stranded RNA |  (dsRNA) viruses in different families of the order
关键词: yadokarivirus |  hetero-encapsidation |  partner dsRNA virus |  fungal virus |  Aspergillus foetidus |  neo-lifestyle
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