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1. Dissolving microneedles for brain delivery: Recent advances and challenges NSTL国家科技图书文献中心

Kaustubh Ajit Koleka... |  Popat S. Kumbhar... -  《Drug discovery today》 - 2025,30(4) - 104330~104330 - 共10页

摘要:Over the past decade, dissolving microneedles |  (DMNs) have emerged as a promising approach for drug |  delivery to the brain. They are tiny devices designed to |  penetrate biological barriers, offering a painless method |  for localized and controlled drug delivery. They are
关键词: brain delivery; dissolving microneedles; minimally invasive devices; neurodegenerative diseases.

2. Advances in dissolving microneedles-based drug delivery system for treating dermatological diseases NSTL国家科技图书文献中心

Chen, Gang |  Li, Jiaying... -  《Journal of drug delivery science and technology》 - 2025,107 - 106785~106785 - 共18页

摘要: dermatological diseases treatment, dissolving MNs (DMNs) loaded | Different from common methods for |  with active pharmaceutical ingredients (APIs) have |  been identified as a promising approach for the |  delivery of drugs and vaccines, which revolutionize drug
关键词: Dissolving microneedles |  Dermatological diseases |  Transdermal drug delivery system

3. Enhanced efficacy of brucine dissolving-microneedles as a targeted delivery system in rheumatoid arthritis treatment: a comprehensive pharmacokinetic-pharmacodynamic analysis NSTL国家科技图书文献中心

Wang, Yunxia |  Yang, Changfu... -  《Drug delivery and translational research》 - 2025,15(2) - 523~533 - 共11页

摘要: therapeutic efficacy of brucine dissolving-microneedles (Bru |  microneedles showed enhanced distribution and prolonged | Our previous studies have shown the | -DMNs) in treating rheumatoid arthritis (RA). Bru |  delivered via the DMNs can bypass some of the issues
关键词: Rheumatoid arthritis |  Brucine dissolving-microneedles |  Microdialysis |  UPLC-MS/MS |  PK-PD modeling

4. Fabrication and characterization of dissolving microneedles combining digital light processing and vacuum compression molding technique for the transdermal delivery of rivastigmine NSTL国家科技图书文献中心

Monou, Paraskevi Kyr... |  Saropoulou, Eirini... -  《European journal of pharmaceutics and biopharmaceutics》 - 2025,210 - Article 114687~Article 114687 - 共13页

摘要:Dissolving microneedles (MNs) are promising |  dissolving inside the interstitial fluid and releasing the |  process was employed to fabricate dissolving MNs |  dissolving MN arrays that are effective and safe for |  transdermal drug delivery systems that can effectively
关键词: Dissolving microneedles |  Microneedle fabrication |  Vacuum Compression Molding (VCM) |  Free-d Molding |  Transdermal delivery

5. Imiquimod nanocrystal-loaded dissolving microneedles prepared by DLP printing NSTL国家科技图书文献中心

Petrova, Eliska |  Chvila, Stanislav... -  《Drug delivery and translational research》 - 2025,15(1) - 158~170 - 共13页

摘要: microneedles encounters the problem of drug solubility in |  cylindrical microneedles arranged in a square grid | The utilization of 3D printing- digital light |  processing (DLP) technique, for the direct fabrication of |  printing resin, especially if it is predominantly
关键词: Microneedles |  3D printing |  Nanocrystals |  Imiquimod |  Dermal delivery

6. Resveratrol nanocrystals based dissolving microneedles with highly efficient for rheumatoid arthritis NSTL国家科技图书文献中心

Diao, Ningning |  Liu, Yan... -  《Drug delivery and translational research》 - 2025,15(1) - 203~215 - 共13页

摘要: delivery system (Res-NC MNs) of dissolved microneedles |  microneedles prepared from hyaluronic acid (HA) by vacuum |  AbstractSchematic diagram of resveratrol nanocrystals microneedles | Rheumatoid arthritis (RA) is a common immune |  disease characterized mainly by erosive arthritis with
关键词: Dissolvable microneedles |  Nanocrystals |  Resveratrol |  Rheumatoid arthritis

7. Hyaluronic acid-based hesperidin nanostructured lipid carriers loaded dissolving microneedles: A localized delivery approach loaded for the management of obesity NSTL国家科技图书文献中心

Gopan, Gopika |  Jose, Jobin... -  《International Journal of Biological Macromolecules》 - 2025,305(Pt.2) - 共26页

摘要: incorporating the NLCs into microneedles (MNs). By developing | Obesity, a persistent imbalance of calories | , has become one of the major clinical factors that |  result in many metabolic disorders. Despite excellent |  anti-obesity properties, the poor aqueous solubility
关键词: Obesity |  Hesperidin |  Nanostructured lipid carriers |  Transdermal drug delivery |  Microneedles

8. Novel double-layered PLGA microparticles-dissolving microneedle (MPs-DMN) system for peptide drugs sustained release by transdermal delivery NSTL国家科技图书文献中心

Xu, Bo |  Liu, Han... -  《International Journal of Pharmaceutics》 - 2025,670 - 125128~125128 - 共13页

摘要: dissolving microneedles (DMN) represents a promising |  doublelayered microparticles-dissolving microneedle (MPs-DMN |  double-layered dissolving microneedle. Microscopic | The combination of microparticles (MPs) with |  transdermal approach for the sustained release of
关键词: Dissolving microneedles |  Double-layered |  PLGA Microparticles |  Peptide drugs |  Sustained release

9. Potential application of matrine microneedles for the treatment of atopic dermatitis in joint skin NSTL国家科技图书文献中心

Wang, Peijie |  Shi, Yuwei... -  《International Journal of Pharmaceutics》 - 2025,668 - 124992~124992 - 共12页

摘要:. This underscores the importance of dissolving |  microneedles (DMNs) used in AD treatment having strong skin | Atopic dermatitis (AD) commonly manifests in |  skin areas subjected to flexion, particularly joints |  adhesion to prevent drug delivery interruption due to
关键词: Atopic dermatitis |  Dissolving microneedles |  Skin adhesion |  Matrine |  Joint skin application

10. Dissolving cinnamaldehyde HA/PVA microneedles for the treatment of skin diseases caused by Microsporum canis NSTL国家科技图书文献中心

Yang, Yang |  Deng, Xin... -  《Journal of drug delivery science and technology》 - 2025,107 - 106841~106841 - 共12页

摘要: molecular docking. CA was formulated into a dissolving | . cains skin diseases. Microneedles administration | Microsporum canis (M. cains) skin diseases are |  zoonotic, which cause serious diseases. Therefore, it is |  crucial to prevent and treat M. cain's skin diseases in
关键词: Microneedles |  Cinnamaldehyde |  Fungal skin diseases |  Network pharmacology |  Microsporum canis |  Treatment
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