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1. Glucocorticoid promotes metastasis of colorectal cancer via co-regulation of glucocorticoid receptor and TET2 NSTL国家科技图书文献中心

Song, Yanwei |  Ren, Shuqiang... -  《International Journal of Cancer》 - 2025,156(8) - 1572~1582 - 共11页

摘要: glucocorticoid receptor (GR) and ten-eleven translocation | Glucocorticoids (GCs), commonly used for anti | -inflammatory and cancer treatments, have been linked to the |  promotion of cancer metastasis. Yet, the molecular |  mechanisms behind this potential remain poorly understood
关键词: colorectal cancer |  drug repositioning |  glucocorticoid receptor |  TET2

2. Prolonged glucocorticoid use and rheumatoid arthritis-associated cervical spine deformity NSTL国家科技图书文献中心

Lebouille-Veldman, A... |  Huizinga, Tom W. J.... -  《Clinical rheumatology》 - 2025,44(5) - 1919~1926 - 共8页

摘要: association between glucocorticoid use and RA-associated |  Duration and dose of glucocorticoid use were evaluated in |  duration of glucocorticoid use, the adjusted OR for RA |  glucocorticoid in total cumulative dose, the OR was 1.06 (95 |  glucocorticoids, although it is known that their long-term use
关键词: Atlantoaxial subluxation |  Cervical spine deformity |  Glucocorticoid use |  Rheumatoid arthritis |  Vertical translocation

3. FKBP5 mediates glucocorticoid signaling in estrogen deficiency-associated endothelial dysfunction NSTL国家科技图书文献中心

Zhu, Ruiwen |  Xu, Yiyue... -  《European Journal of Pharmacology》 - 2025,996 - Article 177598~Article 177598 - 共11页

摘要: glucocorticoid levels, remain poorly understood. This study |  (FKBP5) in mediating glucocorticoid-induced endothelial |  elevated glucocorticoid levels. FKBP5 expression was | . Conclusion: FKBP5 mediates glucocorticoid-induced | Background: Cardiovascular disease (CVD) is
关键词: Endothelial dysfunction |  Estrogen deficiency |  Glucocorticoid signaling |  FKBP5 |  Oxidative stress |  Inflammation |  Cardiovascular disease

4. Convergent effects of synthetic glucocorticoid dexamethasone and amyloid beta in human olfactory neurosphere‐derived cells NSTL国家科技图书文献中心

Zane Farnum |  Radhika Mani... -  《Journal of neurochemistry.》 - 2025,169(2) - e16263~e16263 - 共20页

摘要: glucocorticoid (stress) hormones appear to increase the risk of |  accumulating in the preclinical disease stage, glucocorticoid |  disrupt glucocorticoid receptor signalling. To explore |  synthetic glucocorticoid dexamethasone and Aβ have |  influences canonical glucocorticoid receptor function
关键词: Alzheimer's disease |  glucocorticoid |  immune |  interferon |  mitochondria |  proteomics

5. Glucocorticoid treatment and adrenal suppression in children: current view and open issues NSTL国家科技图书文献中心

Nicola,Improda |  Laura,Chioma... -  《Journal of endocrinological investigation.》 - 2025,48(1) - 37~52 - 共16页

摘要:. Glucocorticoid-induced adrenal insufficiency (GI-AI) is indeed | -systemic glucocorticoid formulations. This review aims at | Abstract Purpose Glucocorticoids (GCs) are |  commonly used for several acute and chronic pediatric |  diseases. However, chronic treatment may result in
关键词: Glucocorticoid-induced adrenal insufficiency |  Adrenal crisis |  Adrenal suppression |  Steroid treatment |  Glucocorticoid replacement

6. Glucocorticoid therapy in classic congenital adrenal hyperplasia: traditional and new treatment paradigms NSTL国家科技图书文献中心

Bancos, Irina |  Kim, Hyunwoo... -  《Expert review of endocrinology & metabolism》 - 2025,20(1) - 33~49 - 共17页

摘要: androgens, typically with supraphysiologic glucocorticoid | IntroductionClassic congenital adrenal |  hyperplasia due to 21-hydroxylase deficiency (CAH) is a rare |  genetic condition characterized by cortisol deficiency |  and excess adrenal androgens. CAH treatment is a
关键词: Androgen |  congenital adrenal hyperplasia |  glucocorticoid |  glucocorticoid replacement dose |  physiologic glucocorticoid dose |  treatment challenges

7. Management of Glucocorticoid-Induced Hyperglycemia in Cancer Patients: A Feasibility Study NSTL国家科技图书文献中心

Wright, Jenny |  Nielsen, Theresa... -  《Clinical nursing research》 - 2025,34(1) - 3~11 - 共9页

摘要: glucocorticoid-induced hyperglycemia (GIH) in non-diabetic |  patients requiring high-dose glucocorticoid (HDG |  days of glucocorticoid therapy (GT) plus one extra | Glucocorticoids are commonly used in the |  management of patients with hematological and solid
关键词: high-dose glucocorticoids |  glucocorticoid-induced hyperglycemia |  nurse-led model of care |  oncology |  clinical research areas |  hematology

8. Prenatal glucocorticoid exposure and congenital abdominal wall defects: Involvement of CXCR4-SDF-1 signaling NSTL国家科技图书文献中心

Bablok, Martin |  Morosan-Puopolo, Gab...... -  《Mechanisms of Ageing and Development》 - 2025,223 - 112008~112008 - 共10页

摘要: further, dexamethasone (DEX), a synthetic glucocorticoid | . Importantly, a downregulation of Glucocorticoid Receptors | Developmental defects of the ventral abdominal |  wall, such as gastroschisis, have been associated |  with prenatal stress exposure. To investigate this
关键词: Prenatal stress |  Chicken embryo |  Congenital defect |  Glucocorticoid

9. Distinct effects of glucocorticoid on pseudorabies virus infection in neuron-like and epithelial cells NSTL国家科技图书文献中心

Lian, Zhengmin |  Zhao, Yuan... -  《Journal of Virology》 - 2025,99(2) - e01472-24~e01472-24 - 共21页

摘要: glucocorticoid family that is widely used in clinical treatment |  as a high-efficiency glucocorticoid receptor (GR |  distinct regulatory mechanisms of glucocorticoid during |  biological functions of glucocorticoid during PRV infection | Pseudorabies virus (PRV) is a porcine
关键词: PRV infection |  IE180 |  glucocorticoid |  neuron-like cells |  productive infection

10. Decreasing miR-433-3p Activity in the Osteoblast Lineage Blunts Glucocorticoid-mediated Bone Loss NSTL国家科技图书文献中心

Prachi Thakore |  Sangita Karki... -  《Endocrinology》 - 2025,166(2) - bqaf008~bqaf008 - 共11页

摘要:Glucocorticoid excess causes bone loss due to | , and endogenous glucocorticoid signaling. To examine |  the impact of miR-433-3p on glucocorticoid-mediated |  indirectly regulates glucocorticoid-mediated |  decreased bone formation and increased bone resorption
关键词: glucocorticoid; microRNA; osteoclast; osteocyte; sclerostin/Sost; tough decoy.
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