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1. Anti-GM-CSF autoantibodies in myeloid leukemias NSTL国家科技图书文献中心

Sergeeva, Anna |  Leung, Wingchi K.... -  《Best practice & research: Clinical haematology》 - 2025,38(1) - 101611~101611 - 共9页

摘要: factor (GM-CSF) is a multifunctional cytokine integral |  myeloid lineage. Recombinant human GM-CSF (rhGM-CSF |  anti-GM-CSFautoantibodies (GM-CSF-Ab) that have been | . Furthermore, anti-GM-CSF-Ab have been linked to myeloid | . The mechanisms behind anti-GM-CSF-Ab production and
关键词: GM-CSF |  Anti-GM-CSF antibody |  Anti-GM-CSF autoantibodies |  AML |  CML |  MDS |  Autoantibody |  PAP |  Pulmonary alveolar proteinosis |  Myeloid malignancies

2. Mechanistic insights into granulocyte-macrophage colony-stimulating factor in combating fungal infections: Diverse fungal pathogens NSTL国家科技图书文献中心

Dong, Qi |  Wu, Weiwei... -  《Medical mycology》 - 2025,63(5) - myaf044~myaf044 - 共8页

摘要: factor (GM-CSF) has been used for its immunomodulatory |  GM-CSF action in various fungal infections have not |  comprehensive analysis of how GM-CSF supports host defense | ). These insights underscore the potential of GM-CSF as a |  granulocyte-macrophage colony-stimulating factor, a key
关键词: GM-CSF |  fungal pathogens |  anti-GM-CSF autoantibodies |  neutrophils |  macrophages

3. GM-CSF自己抗体による肺胞蛋白症 NSTL国家科技图书文献中心

中田光 -  《炎症と免疫》 - 2025,33(3) - 73~77 - 共5页

摘要:病理学的に診断された肺胞蛋白症のうち92%は,血清中に抗GM-CSF自己抗体が証明される自己 | ある.GM-CSFの4つのmajorなαヘリックスのどれにも結合しうるが,3つ目のαヘリックスにホット | スポットが認められる.近年抗GM-CSF自己抗体は,クローン病,重症筋無力症,播種性クリプトコッカス症 | 免疫性肺胞蛋白症である.この自己抗体は,健常者の血清中にもごく微量に存在するが,本症では,1.65 U | /m/以上と高値である.ポリクローナル中和抗体であり,数 pM〜数百pMとhigh avidityで
关键词: 自己免疫性肺胞蛋白症; 抗GM-CSF自己抗体; GM-CSF吸入療法

4. Identification of BHLHE40-Expressing CD4+ T Cells Producing GM-CSF in Rheumatoid Arthritis NSTL国家科技图书文献中心

Sho Ishigaki |  Katsuya Suzuki... -  《International journal of rheumatic diseases》 - 2025,28(4) - e70219~e70219 - 共12页

摘要:-stimulating factor (GM-CSF: CSF2) plays a crucial role in |  important for GM-CSF production in CD4+ T cells. However |  BHLHE40, which is crucial for GM-CSF production, IL1R1 | Background: Granulocyte-macrophage colony |  the pathogenesis of autoimmune diseases. The basic
关键词: BHLHE40; GMCSF; RNA‐seq; T cells; cytokines.

5. Porcine GM-CSF and APS as a novel complex immunostimulant improves the immune effect of pseudorabies inactivated vaccine NSTL国家科技图书文献中心

Chen, Peng |  Zhang, Wuchao... -  《Veterinary Microbiology》 - 2025,304 - 共8页

摘要: factor (GM-CSF) and astragalus polysaccharide (APS |  that neither porcine GM-CSF (pGM-CSF) nor APS | . Moreover, the group treated with pGM-CSF+APS |  challenge, the PR vaccine with pGM-CSF and APS alleviated |  treated with PR vaccine+pGM-CSF and PR vaccine+APS
关键词: GM-CSF |  APS |  Complex Immunostimulant

6. Granulocyte macrophage colony stimulating factor in virus-host interactions and its implication for immunotherapy NSTL国家科技图书文献中心

Bouzeineddine, Nasry... |  Philippi, Alecco... -  《Cytokine & growth factor reviews》 - 2025,81 - 54~63 - 共10页

摘要:. GM-CSF signaling plays a pivotal role in regulating |  with GM-CSF signaling proteins and summarizes |  findings on the impact of viral infections on GM-CSF |  around GM-CSF are investigated, such as the potential |  benefits of administering GMCSF versus inhibiting GM-CSF
关键词: GM-CSF |  virus |  macrophage |  innate immunity |  inflammation |  antiviral therapeutics

7. In situ production and precise release of bioactive GM-CSF and siRNA by engineered bacteria for macrophage reprogramming in cancer immunotherapy NSTL国家科技图书文献中心

Wang, Yaxin |  Fan, Yali... -  《Biomaterials》 - 2025,317 - 共14页 - 被引量:1

摘要: (GM-CSF) to promote M2-like TAMs repolarization to |  the production of GM-CSF, and outer membrane |  continuously produce and release bioactive GM-CSF and SIRP |  secrete granulocyte-macrophage colony-stimulating factor | In the immunosuppressive tumor
关键词: Engineered bacteria |  Macrophage reprograming |  Cancer immunotherapy |  Optogenetics |  Outer membrane vesicles

8. Substance P and neurokinin 1 receptor boost the pathogenicity of granulocyte-macrophage colony-stimulating factor-producing T helper cells in dry eye disease NSTL国家科技图书文献中心

Rong, Hua |  Yang, Hai... -  《Scandinavian journal of immunology.》 - 2025,101(1) - e13434~e13434 - 共12页

摘要:-stimulating factor (GM-CSF) expression while mildly | , NKA did not change GM-CSF expression but |  granulocyte-macrophage colony-stimulating factor-producing T |  significantly promoted granulocyte-macrophage colony | Dry eye disease (DED) is an inflammatory
关键词: dry eye disease |  inflammation |  neurokinin 1 receptor |  substance P |  T cells

9. Alveolar epithelial cells shape lipopolysaccharide‐induced inflammatory responses and reprogramming of alveolar macrophages NSTL国家科技图书文献中心

Wei Jiang |  Yeying Chen... -  《European journal of immunology.》 - 2025,55(1) - 2350378~2350378 - 共15页

摘要: induces AECs to release GMCSF, which potentiates AMs | Abstract Alveolar macrophages (AMs) are |  sentinels in the airways, where they sense and respond to |  invading microbes and other stimuli. Unlike macrophages |  in other locations, AMs can remain responsive to
关键词: Alveolar epithelial cells (AECs) |  Alveolar macrophages (AMs) |  Granulocytemacrophage colonystimulating factor (GMCSF) |  Macrophage reprogramming

10. Human Microglia-Like Cells Differentiated from Monocytes with GM-CSF and IL-34 Show Phagocytosis of α-Synuclein Aggregates and C/EBPβ-Dependent Proinflammatory Activation NSTL国家科技图书文献中心

Llaves-Lopez, Andrea |  Micoli, Elia... -  《Molecular Neurobiology》 - 2025,62(1) - 756~772 - 共17页

摘要: human monocytes using granulocyte-macrophage colony | -stimulating factor and interleukin-34. To this end, 49 | Microglia, the main resident immune cells in |  the central nervous system, are implicated in the |  pathogenesis of various neurological disorders. Much of our
关键词: Microglia |  Cell culture |  Monocyte-derived |  Neuroinflammation |  In vitro model |  C/EBPbeta
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