NSTL国家科技图书文献中心

1. Redefining phenotypic intratumor heterogeneity of pancreatic ductal adenocarcinoma: a bottom-up approach NSTL国家科技图书文献中心

Hilmi, Marc | Delecourt, Flore ... - 《Journal of Pathology》 - 2025,265(4) - 448～461 - 共14页

摘要：Pancreatic ductal adenocarcinoma (PDAC) tumor | interpatient heterogeneity has been well described with two | major prognostic subtypes (classical and basal-like | ). An important intrapatient heterogeneity has been | reported but has not yet been studied extensively due to

关键词： pancreatic ductal adenocarcinoma | image analysis | molecular subtypes | tumoral heterogeneity

2. Implementing proximity care for people with multiple sclerosis in Italy: the bottom-up approach of the StayHome project NSTL国家科技图书文献中心

Filippi, M. | Gallo, P.... - 《Journal of neurology》 - 2025,272(1) - Article: 96～Article: 96 - 共16页

摘要： efficacy of a bottom-up approach* in addressing* | ObjectiveIn Italy, around 137,000 people live | with multiple sclerosis, facing organizational | complexities due to the current model's limited focus on | proximity care. This project aims to define a proximity

关键词： Proximity care | Multiple sclerosis care pathway | Organizational improvement

3. A bottom-up approach identifies the antipsychotic and antineoplastic trifluoperazine and the ribose derivative deoxytubercidin as novel microglial phagocytosis inhibitors NSTL国家科技图书文献中心

Rodriguez-Iglesias, ... | Paris, Inaki ... - 《Glia》 - 2025,73(2) - 330～351 - 共22页

摘要： potential. We used a bottom-up strategy that consisted on | validated our bottom-up strategy to identify novel | Phagocytosis is an indispensable function of | microglia, the brain professional phagocytes. Microglia is | particularly efficient phagocytosing cells that undergo

关键词： apoptosis | deoxytubercidin | hts | microglia | phagocytosis | screening | trifluoperazine

4. Engaging engineering teams through moral imagination: a bottom-up approach for responsible innovation and ethical culture change in technology companies NSTL国家科技图书文献中心

Benjamin,Lange | Geoff,Keeling ... - 《AI and Ethics》 - 2025,5(1) - 607～616 - 共10页

摘要： companies. Our approach* has been operationalized over the* | organization. We argue that our approach* is a crucial* | We propose a ‘Moral Imagination | ’ methodology to facilitate a culture of responsible | innovation for engineering and product teams in technology

关键词： Ethical culture | Responsible innovation | AI ethics | Ethics in technology | Moral imagination | Culture change management | Ethical awareness | Ethical deliberation | Ethical-decision-making | Bottom-up methodology...

5. Open-access Measurement Uncertainty Calculator MUCalc and its application to the quantification of Etizolam in tablets using High-Performance Liquid Chromatography (HPLC) NSTL国家科技图书文献中心

Joyce K. Klu | Roberto Puch-Solis ... - 《Science & justice》 - 2025,65(1) - 70～81 - 共12页

摘要： Calculator (MUCalc) based on a bottom-up approach. The | -up and the top-down approaches. The bottom-up | for estimating measurement uncertainty: the bottom | approach has been suggested in current practice guides | an easy-to-follow approach. This makes it easy for

关键词： Bottom-up approach; Calibration curve; Etizolam; Measurement uncertainty software; Synthetic

6. Elastic Properties and Energy Absorption of Irregular Auxetic Cellular Structure NSTL国家科技图书文献中心

Zhang, Xinru | Deng, Qingtian ... - 《Journal of Materials Engineering and Performance》 - 2025,34(1) - 419～432 - 共14页

摘要： multi-step bottom-up approach. Meanwhile, the effect | the representative unit cell element approach* and* | Based on Euler-Bernoulli beam theory, the | equivalent elastic properties of auxetic cellular structure | with irregular configurations are derived by using

关键词： auxetic cellular structure | energy absorption | irregular | multi-step bottom-up approach | the representative unit cell element approach

7. Carbon peak roadmap for China's major energy-intensive industries: a bottom-up modeling approach NSTL国家科技图书文献中心

Jing Zhang | Yinglan Xue ... - 《Energy,Ecology and Environment》 - 2025,10(2) - 167～181 - 共15页

摘要：Previous research has lacked a comprehensive | study of the coupling and connections between China's | four major energy-intensive industries: electricity | , steel, cement, and coal chemicals, which contribute to | over 65% of China's total carbon emissions and

关键词： Energy-intensive industries | Carbon peak | Roadmap | Industrial decarbonization

8. Recent Advances in Biomass-Derived Quantum Dots,Synthesis,and Their Applications NSTL国家科技图书文献中心

Nishtha | Deepanshu Awasthi ... - 《Chemistry Select》 - 2025,10(6) - e202404611～20 - 共20页

摘要： and bottom-up approaches for CQD production from | The development of biomass-derived | nanomaterials like carbon nanotubes(CNT),graphene,and carbon | nanofibers has revolutionized multiple domains in the | scientific and industrial communities.Notably,quantum dots

关键词： Biomass | Bottom up approach | Carbon quantum dots | Fluorescence | Graphene | Green synthesis-Top-down approach

9. Comparison measurements of natural constants based on laser-focused atomic deposition and extreme ultraviolet interference lithography NSTL国家科技图书文献中心

Deng, Xiao | Tang, Zhaohui ... - 《Measurement Science & Technology》 - 2025,36(1) - 1～9 - 共9页

摘要： approach), and silicon lattice spacing (bottom-up | silicon grating is measured using a bottom-up approach | approach) in nanoscale dimensional metrology. For | ) approach, and the deviation between the measured result | Traceability is the foundation of accuracy and

关键词： nanoscale dimensional metrology | traceability approaches | natural constants | laser-focused atomic deposition | extreme ultraviolet interference lithography

10. Beyond the Surface: Navigating Complex Systems via ABMs and Hypergraphs NSTL国家科技图书文献中心

Daniele De Vinco - 《Social Networks Analysis and Mining,Part III》 - International Conference on Advances in Social Networks Analysis and Mining - 2025, - 148～163 - 共16页

摘要： bottom-up approach is agent-based simulation, which | top-down approach, such as hypergraphs, mathematical | Interactions, organization, and emergent | behaviors are fundamental to all complex systems. These | characteristics can be observed in every real-world scenario

摘要：Pancreatic ductal adenocarcinoma (PDAC) tumor | interpatient heterogeneity has been well described with two | major prognostic subtypes (classical and basal-like | ). An important intrapatient heterogeneity has been | reported but has not yet been studied extensively due to

关键词： pancreatic ductal adenocarcinoma | image analysis | molecular subtypes | tumoral heterogeneity

摘要： efficacy of a bottom-up approach* in addressing* | ObjectiveIn Italy, around 137,000 people live | with multiple sclerosis, facing organizational | complexities due to the current model's limited focus on | proximity care. This project aims to define a proximity

关键词： Proximity care | Multiple sclerosis care pathway | Organizational improvement

摘要： potential. We used a bottom-up strategy that consisted on | validated our bottom-up strategy to identify novel | Phagocytosis is an indispensable function of | microglia, the brain professional phagocytes. Microglia is | particularly efficient phagocytosing cells that undergo

关键词： apoptosis | deoxytubercidin | hts | microglia | phagocytosis | screening | trifluoperazine

摘要： companies. Our approach* has been operationalized over the* | organization. We argue that our approach* is a crucial* | We propose a ‘Moral Imagination | ’ methodology to facilitate a culture of responsible | innovation for engineering and product teams in technology

关键词： Ethical culture | Responsible innovation | AI ethics | Ethics in technology | Moral imagination | Culture change management | Ethical awareness | Ethical deliberation | Ethical-decision-making | Bottom-up methodology...

摘要： Calculator (MUCalc) based on a bottom-up approach. The | -up and the top-down approaches. The bottom-up | for estimating measurement uncertainty: the bottom | approach has been suggested in current practice guides | an easy-to-follow approach. This makes it easy for

关键词： Bottom-up approach; Calibration curve; Etizolam; Measurement uncertainty software; Synthetic

摘要： multi-step bottom-up approach. Meanwhile, the effect | the representative unit cell element approach* and* | Based on Euler-Bernoulli beam theory, the | equivalent elastic properties of auxetic cellular structure | with irregular configurations are derived by using

关键词： auxetic cellular structure | energy absorption | irregular | multi-step bottom-up approach | the representative unit cell element approach

摘要：Previous research has lacked a comprehensive | study of the coupling and connections between China's | four major energy-intensive industries: electricity | , steel, cement, and coal chemicals, which contribute to | over 65% of China's total carbon emissions and

关键词： Energy-intensive industries | Carbon peak | Roadmap | Industrial decarbonization

摘要： and bottom-up approaches for CQD production from | The development of biomass-derived | nanomaterials like carbon nanotubes(CNT),graphene,and carbon | nanofibers has revolutionized multiple domains in the | scientific and industrial communities.Notably,quantum dots

关键词： Biomass | Bottom up approach | Carbon quantum dots | Fluorescence | Graphene | Green synthesis-Top-down approach

摘要： approach), and silicon lattice spacing (bottom-up | silicon grating is measured using a bottom-up approach | approach) in nanoscale dimensional metrology. For | ) approach, and the deviation between the measured result | Traceability is the foundation of accuracy and

关键词： nanoscale dimensional metrology | traceability approaches | natural constants | laser-focused atomic deposition | extreme ultraviolet interference lithography

摘要： bottom-up approach is agent-based simulation, which | top-down approach, such as hypergraphs, mathematical | Interactions, organization, and emergent | behaviors are fundamental to all complex systems. These | characteristics can be observed in every real-world scenario

关键词： Complex systems | Hypergraphs | ABMs | Stance detection | LLM | Social networks

4008-161-200 800-990-8900

国家科技图书文献中心

摘要：Pancreatic ductal adenocarcinoma (PDAC) tumor | interpatient heterogeneity has been well described with two | major prognostic subtypes (classical and basal-like | ). An important intrapatient heterogeneity has been | reported but has not yet been studied extensively due to

关键词： pancreatic ductal adenocarcinoma | image analysis | molecular subtypes | tumoral heterogeneity

摘要： efficacy of a bottom-up approach in addressing | ObjectiveIn Italy, around 137,000 people live | with multiple sclerosis, facing organizational | complexities due to the current model's limited focus on | proximity care. This project aims to define a proximity

关键词： Proximity care | Multiple sclerosis care pathway | Organizational improvement

摘要： potential. We used a bottom-up strategy that consisted on | validated our bottom-up strategy to identify novel | Phagocytosis is an indispensable function of | microglia, the brain professional phagocytes. Microglia is | particularly efficient phagocytosing cells that undergo

关键词： apoptosis | deoxytubercidin | hts | microglia | phagocytosis | screening | trifluoperazine

摘要： companies. Our approach has been operationalized over the | organization. We argue that our approach is a crucial | We propose a ‘Moral Imagination | ’ methodology to facilitate a culture of responsible | innovation for engineering and product teams in technology

关键词： Ethical culture | Responsible innovation | AI ethics | Ethics in technology | Moral imagination | Culture change management | Ethical awareness | Ethical deliberation | Ethical-decision-making | Bottom-up methodology...

摘要： Calculator (MUCalc) based on a bottom-up approach. The | -up and the top-down approaches. The bottom-up | for estimating measurement uncertainty: the bottom | approach has been suggested in current practice guides | an easy-to-follow approach. This makes it easy for

关键词： Bottom-up approach; Calibration curve; Etizolam; Measurement uncertainty software; Synthetic

摘要： multi-step bottom-up approach. Meanwhile, the effect | the representative unit cell element approach and | Based on Euler-Bernoulli beam theory, the | equivalent elastic properties of auxetic cellular structure | with irregular configurations are derived by using

关键词： auxetic cellular structure | energy absorption | irregular | multi-step bottom-up approach | the representative unit cell element approach

摘要：Previous research has lacked a comprehensive | study of the coupling and connections between China's | four major energy-intensive industries: electricity | , steel, cement, and coal chemicals, which contribute to | over 65% of China's total carbon emissions and

关键词： Energy-intensive industries | Carbon peak | Roadmap | Industrial decarbonization

摘要： and bottom-up approaches for CQD production from | The development of biomass-derived | nanomaterials like carbon nanotubes(CNT),graphene,and carbon | nanofibers has revolutionized multiple domains in the | scientific and industrial communities.Notably,quantum dots

关键词： Biomass | Bottom up approach | Carbon quantum dots | Fluorescence | Graphene | Green synthesis-Top-down approach

摘要： approach), and silicon lattice spacing (bottom-up | silicon grating is measured using a bottom-up approach | approach) in nanoscale dimensional metrology. For | ) approach, and the deviation between the measured result | Traceability is the foundation of accuracy and

关键词： nanoscale dimensional metrology | traceability approaches | natural constants | laser-focused atomic deposition | extreme ultraviolet interference lithography

摘要： bottom-up approach is agent-based simulation, which | top-down approach, such as hypergraphs, mathematical | Interactions, organization, and emergent | behaviors are fundamental to all complex systems. These | characteristics can be observed in every real-world scenario

关键词： Complex systems | Hypergraphs | ABMs | Stance detection | LLM | Social networks

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： efficacy of a bottom-up approach* in addressing* | ObjectiveIn Italy, around 137,000 people live | with multiple sclerosis, facing organizational | complexities due to the current model's limited focus on | proximity care. This project aims to define a proximity

摘要： companies. Our approach* has been operationalized over the* | organization. We argue that our approach* is a crucial* | We propose a ‘Moral Imagination | ’ methodology to facilitate a culture of responsible | innovation for engineering and product teams in technology

摘要： multi-step bottom-up approach. Meanwhile, the effect | the representative unit cell element approach* and* | Based on Euler-Bernoulli beam theory, the | equivalent elastic properties of auxetic cellular structure | with irregular configurations are derived by using