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1. Update on B-cell maturation antigen-directed therapies in AL amyloidosis NSTL国家科技图书文献中心

Jamroziak, Krzysztof |  Zielonka, Klaudia... -  《British Journal of Haematology》 - 2025,206(3) - 817~831 - 共15页

摘要:Systemic light chain (AL) amyloidosis is a |  responses. However, AL amyloidosis remains incurable, and |  cells in multiple myeloma (MM) and AL amyloidosis |  target in AL amyloidosis. This review aims to provide |  of anti-BCMA therapy in AL amyloidosis.
关键词: AL amyloidosis |  BCMA |  belantamab mafodotin

2. A Pilot Study Assessing the Accuracy of AI ChatGPT Responses for AL Amyloidosis NSTL国家科技图书文献中心

Ludovic Saba |  Raymond Comenzo... -  《European Journal of Haematology》 - 2025,114(3) - 495~499 - 共5页

摘要:ABSTRACT AL amyloidosis is a rare, complex and |  accuracy of AI ChatGPT responses for AL amyloidosis |  82% in answering AL amyloidosis‐related questions |  often challenging disease for both patients and |  healthcare providers. The availability of accurate medical
关键词: AL amyloidosis |  artificial intelligence |  ChatGPT |  hematology |  oncology

3. Safety and Efficacy of Teclistamab in Patients With Relapsed or Refractory AL Amyloidosis NSTL国家科技图书文献中心

Margaret Stalker |  Alfred Garfall... -  《European Journal of Haematology》 - 2025,114(3) - 443~447 - 共5页

摘要: efficacy of teclistamab in patients with AL amyloidosis |  AL amyloidosis. |  patients with biopsy‐proven relapsed/refractory AL |  amyloidosis who were treated with teclistamab from December | ABSTRACT Introduction Teclistamab has
关键词: AL amyloidosis |  bispecific antibody |  safety and efficacy |  teclistamab

4. Antibody Aggregation: A Problem Within the Biopharmaceutical Industry and Its Role in AL Amyloidosis Disease NSTL国家科技图书文献中心

Sheehan, Kate |  Jeon, Hyesoo... -  《The protein journal》 - 2025,44(1) - 1~20 - 共20页

摘要: amyloid light chain (AL) amyloidosis which is |  been applied to AL amyloidosis patients by depleting |  systemic plasma cell cytotoxicity. Amyloid fibrils in AL |  amyloidosis management. We envision that this area of | Due to the large size and rapid growth of the
关键词: Antibody |  Aggregation |  Protein misfolding |  Monoclonal antibody |  Excipient |  AL amyloidosis

5. Outcomes of daratumumab-bortezomib-thalidomide-dexamethasone in treatment-naive systemic AL amyloidosis NSTL国家科技图书文献中心

Khwaja, Jahanzaib |  Ravichandran, Sriram... -  《British Journal of Haematology》 - 2025,206(4) - 1141~1148 - 共8页

摘要:Systemic light chain (AL) amyloidosis is an |  treatment in AL amyloidosis. We report the UK experience |  for the first-line treatment of AL amyloidosis | . Consecutive patients with a new diagnosis of systemic AL |  the UK National Amyloidosis Centre database. One
关键词: amyloidosis |  chemotherapy |  immunotherapy

6. Identifying gene expression and cellular pathways involved in glomerular AL-amyloidosis and correlation with experimental data: seeking novel therapeutic interventions NSTL国家科技图书文献中心

Herrera, Guillermo A... |  Teng, Jiamin... -  《Ultrastructural pathology》 - 2025,49(2) - 216~234 - 共19页

摘要: amyloidosis were interrogated using spatial transcriptomics |  amyloidosis, uncovering novel genes and new therapeutic | The prognosis of myeloma is based on |  controlling the plasma cell burden and thus, management of |  the production of monoclonal light chains has
关键词: AL-amyloidosis |  cellular pathways |  endocytosis |  gene expression |  HSP90AB1 |  HSPB1 |  kidney |  lysosomes |  mesangial cells |  monoclonal light chains...

7. Presentation and Outcomes of Localized Immunoglobulin Light Chain Amyloidosis: 14-Year Experience of an Academic Center NSTL国家科技图书文献中心

Dima, Danai |  Goel, Utkarsh... -  《Hematological oncology》 - 2025,43(3) - e70082~e70082 - 共9页

摘要:Localized light chain amyloidosis (loc-AL) is |  evidence of systemic AL amyloidosis. We calculated local |  progress to systemic AL amyloidosis. Observation and/or |  deposition of misfolded AL fibrils. There are limited data |  patients with loc-AL at our institution between January 1
关键词: AL amyloidosis |  amyloidosis |  localized AL amyloidosis |  localized amyloidosis |  plasma cell disorder

8. Cardiovascular magnetic resonance-derived left atrioventricular coupling index as a novel prognostic marker for light-chain amyloidosis NSTL国家科技图书文献中心

Wang, Yinqiu |  Bi, Keying... -  《International Journal of Cardiology》 - 2025,418 - 132630~132630 - 共9页

摘要:-chain (AL) amyloidosis. Methods: We prospectively |  enrolled 179 patients with AL amyloidosis who underwent |  independent prognostic value in AL amyloidosis. The LACI has | Background: Left atrioventricular coupling |  index (LACI) is a novel biomarker, and the prognostic
关键词: Cardiovascular magnetic resonance imaging |  Left atrioventricular coupling index |  Light-chain (AL) amyloidosis |  Prognosis

9. Primary systemic amyloidosis: A brief overview NSTL国家科技图书文献中心

Hughes, Michael Sang |  Lentzsch, Suzanne -  《La Presse medicale》 - 2025,54(1) - 104267~104267 - 共7页

摘要: (AL) amyloidosis, is a rare lymphoproliferative | Primary systemic amyloidosis, or light chain |  comprehensivesummary of the pathophysiology and manifestations of AL |  amyloidosis; standard-of-care diagnosticapproach; typical |  disorder in whichaberrant light-chain immunoglobulins
关键词: Primary systemic amyloidosis |  Plasma cell dyscrasias |  Novel therapeutics |  Diagnostic testing

10. Treatment of Refractory Monoclonal Immunoglobulin Deposition Disease With BCMA Bispecific Antibody NSTL国家科技图书文献中心

Bhutani, Divaya |  Chakraborty, Rajshek...... -  《European Journal of Haematology》 - 2025,114(4) - 700~703 - 共4页

摘要:Monoclonal immunoglobulin deposition disease |  patients with refractory monoclonal immunoglobulin |  deposition disease. |  (MIDD) is characterized by deposits of intact |  monoclonal immunoglobulin protein, most commonly in the
关键词: BCMA bispecific antibody |  light chain deposition disease |  monoclonal immunoglobulin deposition disease
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