NSTL国家科技图书文献中心

1. DESIGN AND SYNTHESIS OF RUPESTONIC ACID DERIVATIVESAND ASSESSMENT OF THEIR CYTOTOXIC ACTIVITY NSTL国家科技图书文献中心

Zhu, R. Y. | Bozorov, Kh.... - 《Chemistry of Natural Compounds》 - 2025,61(2) - 289～296 - 共8页

摘要： designed and synthesized. Their cytotoxic* activity was* | cytotoxic activity against A549 (IC50 = 4.73 mu M) and HT | Twenty novel rupestonic acid amides were | assessed against four human cancer cell lines (HeLa, HT | -29, A549, and HepG2). Amide derivative 2e exhibited

关键词： rupestonic acid | structure modification | cytotoxic activity

2. Two new diterpenoid alkaloids from the roots of Aconitum nagarum and their cytotoxic activity NSTL国家科技图书文献中心

Hu, Jiang | Ji, Ren ... - 《Journal of Asian natural products research》 - 2025,27(1/2) - 169～175 - 共7页

摘要： isolated alkaloids were tested in vitro for cytotoxic | activity against five gastric tumor cell lines | A chemical investigation on the roots of | Aconitum nagarum afforded two undescribed C-19 | -diterpenoid alkaloids nagarumines D and E (1 and 2). The

关键词： Aconitum nagarum | Ranunculaceae | diterpenoid alkaloid | cytotoxic activity

3. Three new sesquiterpenes with cytotoxic activity from Croton tiglium NSTL国家科技图书文献中心

Zhou, Wen-Ying | Zheng, Xiao-Xiao ... - 《Phytochemistry Letters》 - 2025,67 - 共7页

摘要：-3 were examined for their cytotoxic* activities* | Sesquiterpenes are a class of natural products | known for their diverse structures and biological | activities. In this study, three new sesquiterpenes | , crotiglimins A (1), B (2) and C (3) were isolated from the

关键词： Croton tiglium | Sesquiterpene | Anti-liver cancer | Cytotoxic activity | HepG2 cells

4. Antimicrobial and Cytotoxic Activity of Imidazole and Thiazole Analogs of Polycarpine and Polycarpaurine C NSTL国家科技图书文献中心

Sabutski, Yu. E. | Kovach, S. M.... - 《Chemistry of Natural Compounds》 - 2025,61(2) - 339～345 - 共7页

摘要： Polycarpa, were synthesized. Their cytotoxic* and* | high antibacterial activity* against Staphylococcus* | Analogs of the alkaloids polycarpine and | polycarpaurine C, metabolites of marine ascidians of the genus | antimicrobial activities were comparatively analyzed. A chloro

关键词： alkaloids | polycarpine | polycarpaurine C | Polycarpa sp. | antimicrobial activity | cytotoxic activity

5. Cytotoxic activity of guanidinium copolymers loaded with silver nanoparticles and their interaction with model membranes NSTL国家科技图书文献中心

Gorbunova, Marina | Efimova, Anna ... - 《Colloid and polymer science》 - 2025,303(1) - 147～161 - 共15页

摘要： cytotoxic activity against cancer cell lines. Nano(AGC-VP | , and there were investigated cytotoxic* properties of* | A series of 2,2-diallyl-1,1,3,3 | -tetraethylguanidiniumchloride copolymers with N-vinylpyrrolidone (AGC-VP | ), vinylacetate (AGC-VA), and methacrylic acid (AGC-MAA) were

关键词： 2,2-Diallyl-1,1,3,3-tetraethylguanidinium chloride | Radical polymerization | Copolymers | Nanocomposites | Cytotoxic activity | Liposomes

6. Clerochinoids A-H, aromatic abietane diterpenoids with cytotoxic activity from the roots and stems of Clerodendrum chinense NSTL国家科技图书文献中心

Chen, Jieting | Liu, Zhilong ... - 《Phytochemistry》 - 2025,235 - 共8页

摘要： screened for their cytotoxic* activity against two human* | exhibited enhanced activity* compared to the positive* | control, gefitinib. The succinct structure-activity | Eight previously undescribed aromatic abietane | diterpenoids, clerochinoids A-H (1-8), including seven 17(15

关键词： Clerodendrum chinense | aromatic abietane diterpenoid | ECD calculation | Cytotoxic activity

7. Design, spectroscopic characterization, in silico and in vitro cytotoxic activity assessment of newly synthesized thymol Schiff base derivatives NSTL国家科技图书文献中心

Basaran, Eyup | Cakmak, Resit ... - 《Journal of Biomolecular Structure and Dynamics》 - 2025,43(8) - 4111～4124 - 共14页

摘要： activity of the molecules was determined against cancer | 72 h. Compounds (14-25) showed cytotoxic* activities* | Cancer is a global public health problem | affecting millions of people every year. New anticancer | drug candidates are needed to overcome the resistance

关键词： Thymol | imino compound | cytotoxic activity | molecular docking

8. Design, Synthesis and In-Vitro Antimicrobial and Cytotoxic Activity Screening of 5-Carboxamide Substituted 3, 4-Dihydropyrimidine-2 (1H) Ones NSTL国家科技图书文献中心

Zar, Fereshteh Solei... | Dilmaghani, Karim A.... - 《Polycyclic Aromatic Compounds》 - 2025,45(2) - 269～284 - 共16页

摘要： concentration methods. The cytotoxic* activities of these* | antibacterial activity* against S. aureus, while compounds 8c* | . Compounds 5h and 8e showed the highest antifungal activity | potent activity* against the tested cancer cell lines* | This paper describes the synthesis and in

关键词： 3,4-dihydropyrimidin-2(1H)-one | carboxamide | antimicrobial activity | cytotoxic activity | synthesis

9. Discovery of Undescribed Flavonoid and Rotenoid Derivatives From the Leaves of Derris trifoliata With Their Cytotoxic Activity NSTL国家科技图书文献中心

Trang, Bui Thi Nha | Anh, Bui Thi Mai ... - 《Chemistry & biodiversity》 - 2025,22(6) - n/a～n/a - 共8页

摘要：. Compounds 1-15 were tested for their cytotoxic* activities* | , and 15 showed moderate cytotoxic* activities against* | Phytochemical study on the leaves of Derris | trifoliata led to the isolation of five rotenoids (3-7) and | 10 flavonoid derivatives (1, 2, 8-15). Three of

关键词： cytotoxic activity | Derris trifoliata | Fabaceae | prenylated flavanone | rotenoid

10. Cytotoxic Activity of Acetone Extracts of Podophyllum peltatum L. Plant Organs and Cell Cultures in Relation to Normal and Tumor Cells NSTL国家科技图书文献中心

Kitaeva, M. P. | Fedotcheva, T. A.... - 《Pharmaceutical Chemistry Journal》 - 2025,58(12) - 1851～1855 - 共5页

摘要： maximum concentration, by 22%. The cytotoxic* activity of* | activity. | The resazurin test was used to show that | acetone extracts of Podophyllum peltatum L. organs | reduced the viability of rat fibroblasts by 33 - 39

摘要： designed and synthesized. Their cytotoxic* activity was* | cytotoxic activity against A549 (IC50 = 4.73 mu M) and HT | Twenty novel rupestonic acid amides were | assessed against four human cancer cell lines (HeLa, HT | -29, A549, and HepG2). Amide derivative 2e exhibited

关键词： rupestonic acid | structure modification | cytotoxic activity

摘要： isolated alkaloids were tested in vitro for cytotoxic | activity against five gastric tumor cell lines | A chemical investigation on the roots of | Aconitum nagarum afforded two undescribed C-19 | -diterpenoid alkaloids nagarumines D and E (1 and 2). The

关键词： Aconitum nagarum | Ranunculaceae | diterpenoid alkaloid | cytotoxic activity

摘要：-3 were examined for their cytotoxic* activities* | Sesquiterpenes are a class of natural products | known for their diverse structures and biological | activities. In this study, three new sesquiterpenes | , crotiglimins A (1), B (2) and C (3) were isolated from the

关键词： Croton tiglium | Sesquiterpene | Anti-liver cancer | Cytotoxic activity | HepG2 cells

摘要： Polycarpa, were synthesized. Their cytotoxic* and* | high antibacterial activity* against Staphylococcus* | Analogs of the alkaloids polycarpine and | polycarpaurine C, metabolites of marine ascidians of the genus | antimicrobial activities were comparatively analyzed. A chloro

关键词： alkaloids | polycarpine | polycarpaurine C | Polycarpa sp. | antimicrobial activity | cytotoxic activity

摘要： cytotoxic activity against cancer cell lines. Nano(AGC-VP | , and there were investigated cytotoxic* properties of* | A series of 2,2-diallyl-1,1,3,3 | -tetraethylguanidiniumchloride copolymers with N-vinylpyrrolidone (AGC-VP | ), vinylacetate (AGC-VA), and methacrylic acid (AGC-MAA) were

关键词： 2,2-Diallyl-1,1,3,3-tetraethylguanidinium chloride | Radical polymerization | Copolymers | Nanocomposites | Cytotoxic activity | Liposomes

摘要： screened for their cytotoxic* activity against two human* | exhibited enhanced activity* compared to the positive* | control, gefitinib. The succinct structure-activity | Eight previously undescribed aromatic abietane | diterpenoids, clerochinoids A-H (1-8), including seven 17(15

关键词： Clerodendrum chinense | aromatic abietane diterpenoid | ECD calculation | Cytotoxic activity

摘要： activity of the molecules was determined against cancer | 72 h. Compounds (14-25) showed cytotoxic* activities* | Cancer is a global public health problem | affecting millions of people every year. New anticancer | drug candidates are needed to overcome the resistance

关键词： Thymol | imino compound | cytotoxic activity | molecular docking

摘要： concentration methods. The cytotoxic* activities of these* | antibacterial activity* against S. aureus, while compounds 8c* | . Compounds 5h and 8e showed the highest antifungal activity | potent activity* against the tested cancer cell lines* | This paper describes the synthesis and in

关键词： 3,4-dihydropyrimidin-2(1H)-one | carboxamide | antimicrobial activity | cytotoxic activity | synthesis

摘要：. Compounds 1-15 were tested for their cytotoxic* activities* | , and 15 showed moderate cytotoxic* activities against* | Phytochemical study on the leaves of Derris | trifoliata led to the isolation of five rotenoids (3-7) and | 10 flavonoid derivatives (1, 2, 8-15). Three of

关键词： cytotoxic activity | Derris trifoliata | Fabaceae | prenylated flavanone | rotenoid

摘要： maximum concentration, by 22%. The cytotoxic* activity of* | activity. | The resazurin test was used to show that | acetone extracts of Podophyllum peltatum L. organs | reduced the viability of rat fibroblasts by 33 - 39

关键词： Podophyllum peltatum L. | phenolic compounds | rat fibroblasts | HeLa | K562 | resazurin test | cytotoxic activity

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： designed and synthesized. Their cytotoxic activity was | cytotoxic activity against A549 (IC50 = 4.73 mu M) and HT | Twenty novel rupestonic acid amides were | assessed against four human cancer cell lines (HeLa, HT | -29, A549, and HepG2). Amide derivative 2e exhibited

关键词： rupestonic acid | structure modification | cytotoxic activity

摘要： isolated alkaloids were tested in vitro for cytotoxic | activity against five gastric tumor cell lines | A chemical investigation on the roots of | Aconitum nagarum afforded two undescribed C-19 | -diterpenoid alkaloids nagarumines D and E (1 and 2). The

关键词： Aconitum nagarum | Ranunculaceae | diterpenoid alkaloid | cytotoxic activity

摘要：-3 were examined for their cytotoxic activities | Sesquiterpenes are a class of natural products | known for their diverse structures and biological | activities. In this study, three new sesquiterpenes | , crotiglimins A (1), B (2) and C (3) were isolated from the

关键词： Croton tiglium | Sesquiterpene | Anti-liver cancer | Cytotoxic activity | HepG2 cells

摘要： Polycarpa, were synthesized. Their cytotoxic and | high antibacterial activity against Staphylococcus | Analogs of the alkaloids polycarpine and | polycarpaurine C, metabolites of marine ascidians of the genus | antimicrobial activities were comparatively analyzed. A chloro

关键词： alkaloids | polycarpine | polycarpaurine C | Polycarpa sp. | antimicrobial activity | cytotoxic activity

摘要： cytotoxic activity against cancer cell lines. Nano(AGC-VP | , and there were investigated cytotoxic properties of | A series of 2,2-diallyl-1,1,3,3 | -tetraethylguanidiniumchloride copolymers with N-vinylpyrrolidone (AGC-VP | ), vinylacetate (AGC-VA), and methacrylic acid (AGC-MAA) were

关键词： 2,2-Diallyl-1,1,3,3-tetraethylguanidinium chloride | Radical polymerization | Copolymers | Nanocomposites | Cytotoxic activity | Liposomes

摘要： screened for their cytotoxic activity against two human | exhibited enhanced activity compared to the positive | control, gefitinib. The succinct structure-activity | Eight previously undescribed aromatic abietane | diterpenoids, clerochinoids A-H (1-8), including seven 17(15

关键词： Clerodendrum chinense | aromatic abietane diterpenoid | ECD calculation | Cytotoxic activity

摘要： activity of the molecules was determined against cancer | 72 h. Compounds (14-25) showed cytotoxic activities | Cancer is a global public health problem | affecting millions of people every year. New anticancer | drug candidates are needed to overcome the resistance

关键词： Thymol | imino compound | cytotoxic activity | molecular docking

摘要： concentration methods. The cytotoxic activities of these | antibacterial activity against S. aureus, while compounds 8c | . Compounds 5h and 8e showed the highest antifungal activity | potent activity against the tested cancer cell lines | This paper describes the synthesis and in

关键词： 3,4-dihydropyrimidin-2(1H)-one | carboxamide | antimicrobial activity | cytotoxic activity | synthesis

摘要：. Compounds 1-15 were tested for their cytotoxic activities | , and 15 showed moderate cytotoxic activities against | Phytochemical study on the leaves of Derris | trifoliata led to the isolation of five rotenoids (3-7) and | 10 flavonoid derivatives (1, 2, 8-15). Three of

关键词： cytotoxic activity | Derris trifoliata | Fabaceae | prenylated flavanone | rotenoid

摘要： maximum concentration, by 22%. The cytotoxic activity of | activity. | The resazurin test was used to show that | acetone extracts of Podophyllum peltatum L. organs | reduced the viability of rat fibroblasts by 33 - 39

关键词： Podophyllum peltatum L. | phenolic compounds | rat fibroblasts | HeLa | K562 | resazurin test | cytotoxic activity

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： designed and synthesized. Their cytotoxic* activity was* | cytotoxic activity against A549 (IC50 = 4.73 mu M) and HT | Twenty novel rupestonic acid amides were | assessed against four human cancer cell lines (HeLa, HT | -29, A549, and HepG2). Amide derivative 2e exhibited

摘要：-3 were examined for their cytotoxic* activities* | Sesquiterpenes are a class of natural products | known for their diverse structures and biological | activities. In this study, three new sesquiterpenes | , crotiglimins A (1), B (2) and C (3) were isolated from the

摘要： Polycarpa, were synthesized. Their cytotoxic* and* | high antibacterial activity* against Staphylococcus* | Analogs of the alkaloids polycarpine and | polycarpaurine C, metabolites of marine ascidians of the genus | antimicrobial activities were comparatively analyzed. A chloro

摘要： cytotoxic activity against cancer cell lines. Nano(AGC-VP | , and there were investigated cytotoxic* properties of* | A series of 2,2-diallyl-1,1,3,3 | -tetraethylguanidiniumchloride copolymers with N-vinylpyrrolidone (AGC-VP | ), vinylacetate (AGC-VA), and methacrylic acid (AGC-MAA) were

摘要： screened for their cytotoxic* activity against two human* | exhibited enhanced activity* compared to the positive* | control, gefitinib. The succinct structure-activity | Eight previously undescribed aromatic abietane | diterpenoids, clerochinoids A-H (1-8), including seven 17(15

摘要： activity of the molecules was determined against cancer | 72 h. Compounds (14-25) showed cytotoxic* activities* | Cancer is a global public health problem | affecting millions of people every year. New anticancer | drug candidates are needed to overcome the resistance

摘要： concentration methods. The cytotoxic* activities of these* | antibacterial activity* against S. aureus, while compounds 8c* | . Compounds 5h and 8e showed the highest antifungal activity | potent activity* against the tested cancer cell lines* | This paper describes the synthesis and in

摘要：. Compounds 1-15 were tested for their cytotoxic* activities* | , and 15 showed moderate cytotoxic* activities against* | Phytochemical study on the leaves of Derris | trifoliata led to the isolation of five rotenoids (3-7) and | 10 flavonoid derivatives (1, 2, 8-15). Three of

摘要： maximum concentration, by 22%. The cytotoxic* activity of* | activity. | The resazurin test was used to show that | acetone extracts of Podophyllum peltatum L. organs | reduced the viability of rat fibroblasts by 33 - 39