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1. DESIGN AND SYNTHESIS OF RUPESTONIC ACID DERIVATIVESAND ASSESSMENT OF THEIR CYTOTOXIC ACTIVITY NSTL国家科技图书文献中心

Zhu, R. Y. |  Bozorov, Kh.... -  《Chemistry of Natural Compounds》 - 2025,61(2) - 289~296 - 共8页

摘要: designed and synthesized. Their cytotoxic activity was |  cytotoxic activity against A549 (IC50 = 4.73 mu M) and HT | Twenty novel rupestonic acid amides were |  assessed against four human cancer cell lines (HeLa, HT | -29, A549, and HepG2). Amide derivative 2e exhibited
关键词: rupestonic acid |  structure modification |  cytotoxic activity

2. Two new diterpenoid alkaloids from the roots of Aconitum nagarum and their cytotoxic activity NSTL国家科技图书文献中心

Hu, Jiang |  Ji, Ren... -  《Journal of Asian natural products research》 - 2025,27(1/2) - 169~175 - 共7页

摘要: isolated alkaloids were tested in vitro for cytotoxic |  activity against five gastric tumor cell lines | A chemical investigation on the roots of |  Aconitum nagarum afforded two undescribed C-19 | -diterpenoid alkaloids nagarumines D and E (1 and 2). The
关键词: Aconitum nagarum |  Ranunculaceae |  diterpenoid alkaloid |  cytotoxic activity

3. Three new sesquiterpenes with cytotoxic activity from Croton tiglium NSTL国家科技图书文献中心

Zhou, Wen-Ying |  Zheng, Xiao-Xiao... -  《Phytochemistry Letters》 - 2025,67 - 共7页

摘要:-3 were examined for their cytotoxic activities | Sesquiterpenes are a class of natural products |  known for their diverse structures and biological |  activities. In this study, three new sesquiterpenes | , crotiglimins A (1), B (2) and C (3) were isolated from the
关键词: Croton tiglium |  Sesquiterpene |  Anti-liver cancer |  Cytotoxic activity |  HepG2 cells

4. Antimicrobial and Cytotoxic Activity of Imidazole and Thiazole Analogs of Polycarpine and Polycarpaurine C NSTL国家科技图书文献中心

Sabutski, Yu. E. |  Kovach, S. M.... -  《Chemistry of Natural Compounds》 - 2025,61(2) - 339~345 - 共7页

摘要: Polycarpa, were synthesized. Their cytotoxic and |  high antibacterial activity against Staphylococcus | Analogs of the alkaloids polycarpine and |  polycarpaurine C, metabolites of marine ascidians of the genus |  antimicrobial activities were comparatively analyzed. A chloro
关键词: alkaloids |  polycarpine |  polycarpaurine C |  Polycarpa sp. |  antimicrobial activity |  cytotoxic activity

5. Cytotoxic activity of guanidinium copolymers loaded with silver nanoparticles and their interaction with model membranes NSTL国家科技图书文献中心

Gorbunova, Marina |  Efimova, Anna... -  《Colloid and polymer science》 - 2025,303(1) - 147~161 - 共15页

摘要: cytotoxic activity against cancer cell lines. Nano(AGC-VP | , and there were investigated cytotoxic properties of | A series of 2,2-diallyl-1,1,3,3 | -tetraethylguanidiniumchloride copolymers with N-vinylpyrrolidone (AGC-VP | ), vinylacetate (AGC-VA), and methacrylic acid (AGC-MAA) were
关键词: 2,2-Diallyl-1,1,3,3-tetraethylguanidinium chloride |  Radical polymerization |  Copolymers |  Nanocomposites |  Cytotoxic activity |  Liposomes

6. Clerochinoids A-H, aromatic abietane diterpenoids with cytotoxic activity from the roots and stems of Clerodendrum chinense NSTL国家科技图书文献中心

Chen, Jieting |  Liu, Zhilong... -  《Phytochemistry》 - 2025,235 - 共8页

摘要: screened for their cytotoxic activity against two human |  exhibited enhanced activity compared to the positive |  control, gefitinib. The succinct structure-activity | Eight previously undescribed aromatic abietane |  diterpenoids, clerochinoids A-H (1-8), including seven 17(15
关键词: Clerodendrum chinense |  aromatic abietane diterpenoid |  ECD calculation |  Cytotoxic activity

7. Design, spectroscopic characterization, in silico and in vitro cytotoxic activity assessment of newly synthesized thymol Schiff base derivatives NSTL国家科技图书文献中心

Basaran, Eyup |  Cakmak, Resit... -  《Journal of Biomolecular Structure and Dynamics》 - 2025,43(8) - 4111~4124 - 共14页

摘要: activity of the molecules was determined against cancer |  72 h. Compounds (14-25) showed cytotoxic activities | Cancer is a global public health problem |  affecting millions of people every year. New anticancer |  drug candidates are needed to overcome the resistance
关键词: Thymol |  imino compound |  cytotoxic activity |  molecular docking

8. Design, Synthesis and In-Vitro Antimicrobial and Cytotoxic Activity Screening of 5-Carboxamide Substituted 3, 4-Dihydropyrimidine-2 (1H) Ones NSTL国家科技图书文献中心

Zar, Fereshteh Solei... |  Dilmaghani, Karim A.... -  《Polycyclic Aromatic Compounds》 - 2025,45(2) - 269~284 - 共16页

摘要: concentration methods. The cytotoxic activities of these |  antibacterial activity against S. aureus, while compounds 8c | . Compounds 5h and 8e showed the highest antifungal activity |  potent activity against the tested cancer cell lines | This paper describes the synthesis and in
关键词: 3,4-dihydropyrimidin-2(1H)-one |  carboxamide |  antimicrobial activity |  cytotoxic activity |  synthesis

9. Discovery of Undescribed Flavonoid and Rotenoid Derivatives From the Leaves of Derris trifoliata With Their Cytotoxic Activity NSTL国家科技图书文献中心

Trang, Bui Thi Nha |  Anh, Bui Thi Mai... -  《Chemistry & biodiversity》 - 2025,22(6) - n/a~n/a - 共8页

摘要:. Compounds 1-15 were tested for their cytotoxic activities | , and 15 showed moderate cytotoxic activities against | Phytochemical study on the leaves of Derris |  trifoliata led to the isolation of five rotenoids (3-7) and |  10 flavonoid derivatives (1, 2, 8-15). Three of
关键词: cytotoxic activity | Derris trifoliata | Fabaceae | prenylated flavanone | rotenoid

10. Cytotoxic Activity of Acetone Extracts of Podophyllum peltatum L. Plant Organs and Cell Cultures in Relation to Normal and Tumor Cells NSTL国家科技图书文献中心

Kitaeva, M. P. |  Fedotcheva, T. A.... -  《Pharmaceutical Chemistry Journal》 - 2025,58(12) - 1851~1855 - 共5页

摘要: maximum concentration, by 22%. The cytotoxic activity of |  activity. | The resazurin test was used to show that |  acetone extracts of Podophyllum peltatum L. organs |  reduced the viability of rat fibroblasts by 33 - 39
关键词: Podophyllum peltatum L. |  phenolic compounds |  rat fibroblasts |  HeLa |  K562 |  resazurin test |  cytotoxic activity
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