NSTL国家科技图书文献中心

1. Merck Animal Health Uses Operations Research Methods to Transform Biomanufacturing Productivity for Lifesaving Medicines NSTL国家科技图书文献中心

Tugce Martagan | Ivo Adan ... - 《INFORMS Journal on Applied Analytics》 - 2023,53(1) - 85～95 - 共11页 - 被引量：4

摘要：Merck Animal Health offers veterinarians | , farmers, pet owners, and governments a wide range of | veterinary pharmaceuticals, vaccines, health management | solutions and services, and an extensive suite of | connected technology that includes identification

关键词： biomanufacturing | life sciences | simulation | data analytics | stochastic modeling | Edelman award

2. Seasonal distribution and dynamic evolution of antibiotics and evaluation of their resistance selection potential and ecotoxicological risk at a wastewater treatment plant in Jinan, China NSTL国家科技图书文献中心

Zhang Hui | Zou Huiyun ... - 《Environmental Science and Pollution Research》 - 2023,30(15) - 44505～44517 - 共13页 - 被引量：5

摘要：Abstract The seasonal distribution and dynamic | evolution of antibiotics in wastewater from main treatment | areas and in sludge and their resistance selection | potential and ecotoxicological risk were studied at a | municipal wastewater treatment plant in Jinan, East China

关键词： Antibiotics | Wastewater treatment plants | Removal | Mass loads | Resistance selection | Ecotoxicological risk

3. Predicting the insecticide-driven mutations in a crop pest insect: Evidence for multiple polymorphisms of acetylcholinesterase gene with potential relevance for resistance to chemicals NSTL国家科技图书文献中心

Renault, David | Elfiky, Abdo ... - 《Environmental Science and Pollution Research》 - 2023,30(7) - 18937～18955 - 共19页 - 被引量：1

摘要：The silverleaf whitefly Bemisia tabaci | (Gennadius, 1889) (Homoptera: Aleyrodidae) is a serious | invasive herbivorous insect pest worldwide. The excessive | use of pesticides has progressively selected B | . tabaci specimens, reducing the effectiveness of the

关键词： Acetylcholinesterase | Environmental toxicants | Resistance | Putative mutations | Homology modeling | Molecular docking | TABACI HEMIPTERA ALEYRODIDAE | HYDROLASE FOLD SUPERFAMILY | AMINO-ACID SUBSTITUTION | BEMISIA-TABACI...

4. Current perspective on veterinary drug and chemical residues in food of animal origin SCIE Web of Science核心 NSTL国家科技图书文献中心

Atta, Attia H. | Atta, Shimaa A.... - 《Environmental Science and Pollution Research》 - 2022,29(11) - 15282～15302 - 共21页 - 被引量：14

摘要：Y The marked increase in the demand for animal | protein of high quality necessitates protecting animals | from infectious diseases. This requires increasing | the use of veterinary therapeutics. The overuse and | misuse of veterinary products can cause a risk to human

关键词： Source of drug residues | Health hazards | Food pollutants | Residue avoidance | SPECTRUM MONOCLONAL-ANTIBODY | LINKED-IMMUNOSORBENT-ASSAY | HUMAN HEALTH-RISK | ANTIBIOTIC-RESIDUES | LIQUID-CHROMATOGRAPHY | MASS-SPECTROMETRY...

5. Biodistribution, pharmacokinetics and toxicity evaluation of mannosylated gelatin nanoparticles of linezolid for anti-tubercular therapy EI 工程索引 SCIE Web of Science核心 NSTL国家科技图书文献中心

K. D. Patil | S. B. Bagade ... - 《Materials Technology》 - 2022,37(1/2) - 95～103 - 共9页 - 被引量：3

摘要：The present study explores the therapeutic | potential of gelatin nanoparticles as a carrier for the | delivery of linezolid, a repurposed drug for the | treatment ofMycobactrium tuberculosis. However, it has | significant issues of large dose and toxicity. To overcome

关键词： Linezolid | gelatin nanoparticles | mannosylation | pharmacokinetic | biodistribution | toxicity

6. Fabrication, drug delivery kinetics and cell viability assay of PLGA-coated vancomycin-loaded silicate porous microspheres EI 工程索引 SCIE Web of Science核心 NSTL国家科技图书文献中心

Zirak N. | Maadani A.M.... - 《CERAMICS INTERNATIONAL》 - 2022,48(1) - 48～54 - 共7页 - 被引量：11

摘要：Porous ceramic microspheres are a desirable | substance for bone tissue reconstruction and delivery | applications. This study focuses on Mg–Ca silicate | microspheres encapsulated in biodegradable poly (lactic-co | -glycolic acid) (PLGA) to serve as a biocompatible carrier

关键词： Antibiotic drug delivery | Biodegradation | Biomedical applications | Biosilicates | Bone substituting biomaterials | Bone void fillers

7. Metal-oxide coated Graphene oxide nano-composite for the treatment of pharmaceutical compound in photocatalytic reactor: Batch, Kinetics and Mathematical Modeling using Response Surface Methodology and Artificial Neural Network SCIE Web of Science核心 NSTL国家科技图书文献中心

Bhattacharya Sandipa... | Das Papita ... - 《Environmental Science and Pollution Research》 - 2022,29(41) - 61938～61953 - 共16页 - 被引量：1

摘要：Abstract Titanium dioxide (TiO2) photocatalyst | has gained constant interest in the treatment of | wastewater because of its greater stability, lower cost | , low-toxicity, high efficiency, and more reactivity | under UV radiation. On the other hand, Graphene oxide

关键词： Graphene Oxide (GO) | Titanium Dioxide (TiO2) | Nanocomposite | Photocatalytic reactor | RSM | ANN

8. Photochemical persistence of sulfa drugs in aqueous medium: kinetic study and mathematical simulations SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Arlen Mabel Lastre-A... | Bruno Segawa Cristof...... - 《Environmental Science and Pollution Research》 - 2021,28(19) - 23887～23895 - 共9页 - 被引量：10

摘要：This study aimed at investigating the | photochemical behavior of sulfa drugs containing five and six | -membered heterocyclic substituents (sulfamethoxazole (SMX | ) and sulfadiazine (SDZ), respectively), in an aqueous | medium. Despite their importance, studies devoted to

关键词： Sulfonamides | Environmental persistence | Reactive photo-induced species (RPS) | Photolysis | Real aqueous matrices | Mathematical modeling

9. Portfolio-Wide Optimization of Pharmaceutical R&D Activities Using Mathematical Programming SCIE Web of Science核心 SSCI 社会科学引文索引 NSTL国家科技图书文献中心

Hua Wang | Jon Dieringer ... - 《INFORMS Journal on Applied Analytics》 - 2021,51(4) - 262～279 - 共18页 - 被引量：2

摘要：The research and development (R&D) management | in any major research pharmaceutical company is | constantly faced with the need to make complicated activity | scheduling and resource allocation decisions, as they carry | out scientific work to develop new therapeutic

关键词： pharmaceutical R&D | CMC (chemistry manufacturing and controls) | project scheduling | mixed-integer linear optimization

10. Wastewater-based epidemiology approach to assess population exposure to pesticides: a review of a pesticide pharmacokinetic dataset SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Devault, Damien Alai... | Karolak, Sara - 《Environmental Science and Pollution Research》 - 2020,27(5) - 4695～4702 - 共8页 - 被引量：16

摘要：Wastewater-based epidemiology is an innovative | approach to estimate a population's intentional and | unintentional consumption of chemicals based on biomarker | assays found in wastewater. This method can provide | real-time objective information on the xenobiotics to