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1. Mendelian randomization and genetic pleiotropy analysis for the connection between inflammatory bowel disease and Alzheimer's disease NSTL国家科技图书文献中心

Wu, Yuxuan |  Yan, Yu... -  《Progress in Neuro-Psychopharmacology & Biological Psychiatry》 - 2025,136 - 111203～111203 - 共12页

摘要：Background: The gut-microbiome-brain axis |  (GMBA) implies the connection between inflammatory |  bowel disease (IBD) and Alzheimer's disease (AD). We |  aimed to comprehensively explore the relation between |  IBD (and its subtypes) and AD, early-onset AD (EOAD
关键词： Inflammatory bowel disease |  Alzheimer's disease |  Gut-microbiome-brain axis |  Vertical and horizontal pleiotropy |  Summary statistics |  Mendelian randomization
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2. Trajectory patterns and influencing factors of supportive care needs in stroke patients: A longitudinal study NSTL国家科技图书文献中心

Xi, Yushan |  Liu, Ranran... -  《Journal of advanced nursing》 - 2025,81(2) - 809～819 - 共11页 - 被引量：1

摘要：AimTo investigate the trajectory patterns and |  influencing factors of supportive care needs in stroke |  patients.DesignA longitudinal study.MethodsIn total, 207 stroke |  patients who received treatment at the Department of |  Neurology in a hospital in Xuzhou between July 2022 and
关键词： developmental trajectory |  latent growth mixture model |  nursing care |  stroke |  supportive care needs
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3. Assessing Stroke Recurrence Risk by Using a Lipoprotein-Associated Phospholipase A2 and Platelet Count-Based Nomogram NSTL国家科技图书文献中心

Zhou, Yanlong |  Feng, Yu... -  《Molecular Neurobiology》 - 2025,62(3) - 2835～2845 - 共11页

摘要：Stroke recurrence remains a critical challenge |  in clinical neurology, necessitating the |  identification of reliable predictive markers for better |  management and treatment strategies. This study |  investigates the interaction between lipoprotein-associated
关键词： Stroke recurrence |  Lp-PLA2 |  Platelets |  Nomogram |  Predictor
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4. Predictors and Prognosis of Early Neurological Outcomes on Patients with Vertebrobasilar Artery Occlusion Undergoing Endovascular Treatment NSTL国家科技图书文献中心

Ma, Xinan |  Li, Yajun... -  《Cerebrovascular diseases》 - 2025,54(1) - 70～80 - 共11页

摘要：Introduction: This research explored the |  factors influencing early neurological outcomes (ENO) in |  patients who had vertebrobasilar artery occlusion (VBAO | ) and received endovascular treatment (EVT), as well |  as examining the causal influence of ENO on the
关键词： Stroke |  Ischemic stroke |  Risk factors |  Thrombectomy
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5. A comparison of the efficacy of computed tomography-guided minimally invasive puncture and drainage and craniotomy for hematoma evacuation in the treatment of cerebellar hemorrhage NSTL国家科技图书文献中心

Xu, Bingzhong |  Quan, Chen... -  《Journal of clinical neuroscience: official journal of the Neurosurgical Society of Australasia》 - 2024,128 - 110743～110743 - 共6页

摘要：Objective: This study aimed to compare the |  efficacy of computed tomography (CT)-guided minimally |  invasive puncture and drainage (MIPD) and craniotomy for |  hematoma evacuation in the treatment of cerebellar |  hemorrhage. Methods: This single-center prospective cohort
关键词： Cerebellar hemorrhage |  Computed tomography (CT) |  Minimally invasive puncture and drainage |  (MIPD) |  Hematoma evacuation |  Craniotomy |  MORTALITY
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6. Synergism of ApoE4 and systemic infectious burden is mediated by the APOE-NLRP3 axis in Alzheimer's disease NSTL国家科技图书文献中心

Liu, Xue-Ting |  Chen, Xiu... -  《Psychiatry and clinical neurosciences》 - 2024,78(9/10) - 517～526 - 共10页

摘要：Background: Systemic infections are associated |  with the development of AD, especially in individuals |  carrying the APOE4 genotype. However, the detailed |  mechanism through which APOE4 affects microglia |  inflammatory response remains unclear. Methods: We obtained
关键词： activation of microglia |  Alzheimer's disease |  apolipoprotein E |  NLRP3 inflammasome |  NLRP3 INFLAMMASOME ACTIVATION |  NEURODEGENERATION |  MICROGLIA |  NEUROINFLAMMATION |  CONTRIBUTES |  AUTOPHAGY...
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7. Dendritic Cell-Related Immune Marker CD1C for Predicting Prognosis and Immunotherapy Opportunities of Lung Adenocarcinoma Patients NSTL国家科技图书文献中心

Zhao, Jing |  Chen, Hao... -  《Applied biochemistry and biotechnology,Part A.enzyme engineering and biotechnology》 - 2024,196(12) - 8724～8740 - 共17页

摘要：Lung adenocarcinoma (LUAD) is the most |  frequent type of lung cancer with a high mortality rate | . Here, we aim to explore novel immune-related |  biomarkers for LUAD patients. Datasets, mRNA expression |  profiles, and clinical data concerned with LUAD were
关键词： Lung adenocarcinoma |  Dendritic cells |  CD1C |  Prognosis |  Immunotherapy
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8. Long-Term Accumulation of T Cytotoxic 1, T Cytotoxic 17, and T Cytotoxic 17/1 Cells in the Brain Contributes to Microglia-Mediated Chronic Neuroinflammation After Ischemic Stroke NSTL国家科技图书文献中心

Shu, Long |  Xu, Hui... -  《Neuromolecular medicine》 - 2024,26 - Article: 17～Article: 17 - 共12页

摘要：Post-stroke neuroinflammation affects the |  damage and recovery of neurological functions. T cells |  including CD8(+) T cells were present in the ipsilateral |  hemisphere in the subacute and late phases of ischemic |  stroke. However, the potential roles of CD8(+) T cell
关键词： Ischemic stroke |  Brain |  CD8(+) T cells |  Neuroinflammation |  Immunity
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9. The role of immune and inflammatory-related indicators in cognitive dysfunction and disease severity in patients with parkinson's disease NSTL国家科技图书文献中心

Zhao, Xudong |  Li, Lei... -  《Journal of neural transmission》 - 2024,131(1) - 13～24 - 共12页

摘要：We aimed to explore the role of immune and |  inflammatory indicators in cognitive dysfunction and disease |  severity in patients with Parkinson's disease (PD). A |  total of 123 patients with Parkinson's disease were |  enrolled in the PD group and 49 healthy volunteers in the
关键词： Parkinson's disease |  Mild cognitive impairment |  Lymphocyte subpopulation |  Inflammatory cytokines |  IMPAIRMENT |  MODEL |  DOPAMINE
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10. Causal Associations between Tea Consumption and Rapid Eye Movement Sleep Behavior Disorder: A Mendelian Randomization Study NSTL国家科技图书文献中心

Li, Jinyu |  Zhang, Zixuan... -  《European neurology》 - 2024,87(5/6) - 250～260 - 共11页

摘要：Introduction: Previous studies have shown that |  tea consumption may have a protective effect against |  neurodegenerative diseases. However, the exact causal relationship |  between tea consumption and the precursor stages of |  certain neurodegenerative diseases, namely, REM sleep
关键词： Mendelian randomization |  Rapid eye movement sleep behavior disorder |  Tea consumption
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