NSTL国家科技图书文献中心

1. Patterns of brain activity in choice or instructed go and no-go tasks NSTL国家科技图书文献中心

Isfahani, Sanaz Atta... | Mcgurrin, Patrick ... - 《Experimental Brain Research》 - 2025,243(3) - Article: 73～Article: 73 - 共10页

摘要：The goal of this study was to investigate the | decision making process for choosing what movements to | make. We used electroencephalography (EEG) to | investigate patterns of the contingent negative variation | (CNV) associated with free-choice decisions to move

关键词： Contingent negative variation | Go/no-go task | Reaction time | Decision | Free will | Motor control

2. Precision neurology NSTL国家科技图书文献中心

Small, Steven L. - 《Ageing Research Reviews》 - 2025,104 - 102632～102632 - 共13页

摘要：Over the past several decades, high-resolution | brain imaging, blood and cerebrospinal fluid analyses | , and other advanced technologies have changed | diagnosis from an exercise depending primarily on the | history and physical examination to a computer- and

关键词： Personalized medicine | Omics | Neurodegenerative disease | Brain simulation | Biomarker | Value-based care

3. Safety and efficacy of chronic weekly rozanolixizumab in generalized myasthenia gravis: the randomized open-label extension MG0004 study NSTL国家科技图书文献中心

Bril, Vera | Druzdz, Artur ... - 《Journal of neurology》 - 2025,272(4) - Article 275～Article 275 - 共13页

摘要：BackgroundIn the Phase 3 MycarinG study | (NCT03971422), six once-weekly subcutaneous infusions of | rozanolixizumab significantly improved myasthenia gravis (MG | )-specific outcomes versus placebo in patients with | acetylcholine receptor or muscle-specific tyrosine kinase

关键词： Myasthenia gravis | Rozanolixizumab | FcRn inhibitor | Phase 3 clinical trial

4. Comprehensive assessment of TDP-43 neuropathology data in the National Alzheimer's Coordinating Center database NSTL国家科技图书文献中心

Woodworth, Davis C. | Nguyen, Katelynn M.... - 《Acta Neuropathologica》 - 2024,147(1) - Article: 103～Article: 103 - 共6页 - 被引量：2

摘要：TDP-43 proteinopathy is a salient | neuropathologic feature in a subset of frontotemporal lobar | degeneration (FTLD-TDP), in amyotrophic lateral sclerosis | (ALS-TDP), and in limbic-predominant age-related TDP | -43 encephalopathy neuropathologic change (LATE-NC

关键词： TDP-43 | Limbic predominant age-related TDP-43 encephalopathy neuropathologic change | Frontotemporal lobar degeneration | Amyotrophic lateral sclerosis | Hippocampal sclerosis of aging | Dementia | Alzheimer's disease | National Alzheimer's coordinating center | FRONTOTEMPORAL LOBAR DEGENERATION | AMYOTROPHIC-LATERAL-SCLEROSIS...

5. A non-enhancing, T2 fluid-attenuated inversion recovery hyperintense, diffusion-restricting brainstem lesion in an EGFR tyrosine kinase inhibitor-treated non-small-cell lung cancer patient NSTL国家科技图书文献中心

Yuen, Carlen A. | Bao, Silin ... - 《Biomarkers in medicine》 - 2024,18(9) - 433～441 - 共9页

摘要：Leptomeningeal metastasis (LM) is a | devastating complication of malignancy. Diagnosis relies on | both contrast enhancement on imaging and malignant | cells in cerebral spinal fluid cytology. Though early | detection and prompt intervention improves survival, the

关键词： brainstem | diffusion restriction | EGFR | leptomeningeal carcinomatosis | leptomeningeal metastases | MRI | non-enhancing | non-small cell lung cancer | osimertinib | T2 FLAIR hyperintensity...

6. The amyloid beta 42/38 ratio as a plasma biomarker of early memory deficits in cognitively unimpaired older adults NSTL国家科技图书文献中心

Bamford, Alison R. | Adams, Jenna N.... - 《Neurobiology of Aging》 - 2024,144 - 12～18 - 共7页

摘要：The amyloid beta (A13) 42/40 ratio has been | widely studied as a biomarker in Alzheimer's disease | (AD); however, other A13 peptides could also | represent relevant biomarkers. We measured levels of A1338 | /40/42 in plasma samples from cognitively-unimpaired

关键词： Alzheimer's disease | Amyloid-beta | Neurodegeneration | Plasma | Biomarker | Delayed recall

7. Ubrogepant users' real-world experience: Patients on ubrogepant, characteristics and outcomes (UNIVERSE) study NSTL国家科技图书文献中心

Shewale, Anand R. | Poh, Weijie ... - 《Headache》 - 2024,64(10) - 1244～1252 - 共9页

摘要：ObjectiveTo assess the real-world | effectiveness of ubrogepant by evaluating self-reported | satisfaction with pain relief, ability to think clearly, and | return to normal function in individuals who had used | ubrogepant to treat a migraine episode within the preceding

关键词： calcitonin gene-related peptide | migraine | outcomes research | ubrogepant | calcitonin gene–related peptide

8. Pembrolizumab in an HIV-infected patient with glioblastoma NSTL国家科技图书文献中心

Yuen, Carlen A. | Bao, Silin ... - 《Immunotherapy》 - 2024,16(12) - 803～811 - 共9页

摘要：Persons living with human immunodeficiency | virus (PLWH) carry increased risk for developing | malignancies, including glioblastoma. Despite extensive | investigations, both human immunodeficiency virus (HIV) and | glioblastoma are incurable. Treatment for a patient with

关键词： cancer disparities | glioblastoma | HIV | HIV latency | HIV reservoir | human immunodeficiency virus | immunotherapy | pembrolizumab | PD-1 | programmed cell death 1 inhibitor...

9. Friedman's Gradient-Boosting Algorithm Predicts Lactate-Pyruvate Ratio Trends in Cases of Intracerebral Hemorrhages NSTL国家科技图书文献中心

Kang J. | Shah I.... - 《World neurosurgery》 - 2024,187 - e620～e628 - 共9页

摘要：? 2024 Elsevier Inc.Objective: The local | effects of an intracerebral hemorrhage (ICH) on | surrounding brain tissue can be detected bedside using | multimodal brain monitoring techniques. The aim of this | study is to design a gradient boosting regression

关键词： Boostmtree | Cerebral microdialysis | Gradient boost | Intracerebral hemorrhage | Multimodal monitoring | Perihematomal zone of edema

10. Pure LATE-NC: Frequency, clinical impact, and the importance of considering APOE genotype when assessing this and other subtypes of non-Alzheimer's pathologies NSTL国家科技图书文献中心

Katsumata, Yuriko | Wu, Xian ... - 《Acta Neuropathologica》 - 2024,148(1) - Article: 66～Article: 66 - 共15页

摘要：Pure limbic-predominant age-related TDP-43 | encephalopathy neuropathologic changes (pure LATE-NC) is a term | used to describe brains with LATE-NC but lacking | intermediate or severe levels of Alzheimer's disease | neuropathologic changes (ADNC). Focusing on pure LATE-NC, we