NSTL国家科技图书文献中心

1. Learning latent causal factors from the intricate sensor feedback of contact-rich robotic assembly tasks NSTL国家科技图书文献中心

Chen, Yurou | Yu, Jiyang ... - 《Robotics and Autonomous Systems》 - 2025,183 - 共12页

摘要：Achieving precise robotic assembly is paramount for safety and performance in industrial settings. Conventional assembly methods require tedious manual adjustment of many parameters, and it is challen...

关键词： Causal inference | Reinforcement learning | Robotic manipulation | Nut insertion

2. SAMPO-P: A prototypical scale low-temperature experiment on two-layer melt pool heat transfer in LWR lower head NSTL国家科技图书文献中心

Guo, Pengya | Quan, Fengyang ... - 《Experimental Thermal and Fluid Science》 - 2025,160 - 共11页

摘要：To better understand the thermal behavior of a two-layer melt pool with a high Rayleigh number-a pattern observed in the RASPLAV study, which indicates a significant risk to pressure vessel integrity ...

关键词： Melt pool | In-vessel retention | Stratified | Two-layer | SAMPO

3. Impact of Age on Pharmacogenomics and Treatment Outcomes of B-Cell Acute Lymphoblastic Leukemia NSTL国家科技图书文献中心

Yoshimura, Satoshi | Li, Zhenhua ... - 《Journal of clinical oncology》 - 2024,42(29) - 3478～3490 - 共13页

摘要：PURPOSE Acute lymphoblastic leukemia (ALL) can occur across all age groups, with a strikingly higher cure rate in children compared with adults. However, the pharmacological basis of age-related diffe...

关键词： MINIMAL RESIDUAL DISEASE | VITRO DRUG-SENSITIVITY | RESISTANCE | CHEMOTHERAPY | PROGNOSIS | PATTERNS | CHILDREN | THERAPY | FUSION | ADULT

4. Folylpolyglutamate synthetase inactivation in relapsed ALL induces a druggable folate metabolic vulnerability NSTL国家科技图书文献中心

Li, Hui | Chen, Yao ... - 《Drug resistance updates》 - 2024,77 - 101141～101141 - 共15页

摘要：Aims: The antifolate methotrexate (MTX) is an anchor drug used in acute lymphoblastic leukemia (ALL) with poorly understood chemoresistance mechanisms in relapse. Herein we find decreased folate polyg...

关键词： Acute lymphoblastic leukemia | Methotrexate | Folylpoly-gamma-glutamate synthetase | Chemoresistance | Folate metabolic vulnerability

5. Research on the effect of heat pipe temperature oscillation on heat pipe cooled reactor operation EI 工程索引 NSTL国家科技图书文献中心

Guo, Yuchuan | Su, Zilin ... - 《Annals of nuclear energy》 - 2023,182(Mar.) - 109587.1～109587.11 - 共11页 - 被引量：7

摘要：Heat pipes have been recognized as the unique equipment of heat absorption for heat pipe cooled reactor. The operating characteristics of heat pipe have the direct effect on the operation of the react...

关键词： Heat pipe | Temperature oscillation | KRUSTY | Thermal diffusion

6. Conceptual design of megawatt-level mobile nuclear power system based on heat pipe cooled reactor NSTL国家科技图书文献中心

Guo, Yuchuan | Guo, Xiaoyu ... - 《Nuclear engineering and design》 - 2023,413(Nov.) - 1.1～1.11 - 共11页 - 被引量：2

摘要：Mobile nuclear power system has the advantages such as the well adaptability, the strong sustainability, and the convenient transportation, which can satisfy the energy demand of special environments ...

关键词： Mobile nuclear power system | Heat pipe cooled reactor | Combined cycle | Modular design

7. Spatiotemporal regulation of cholangiocarcinoma growth and dissemination by peritumoral myofibroblasts in a Vcam1-dependent manner NSTL国家科技图书文献中心

Tian, Cheng | Li, Liyuan ... - 《Oncogene》 - 2023,42(15) - 1196～1208 - 共13页 - 被引量：1

摘要：Intrahepatic cholangiocarcinoma (iCCA) is characterized by its highly desmoplastic stroma. Myofibroblasts (MFs) are present both within the tumor mass (intratumoral MFs, iMFs) and at the tumor border ...

关键词： HEPATIC STELLATE CELLS | HEPATOCELLULAR-CARCINOMA | CANCER | FIBROBLASTS | VCAM-1

8. Targeting DNA polymerase beta elicits synthetic lethality with mismatch repair deficiency in acute lymphoblastic leukemia NSTL国家科技图书文献中心

Teng, Ji-Yuan | Yang, Ding-Peng ... - 《Leukemia: Official journal of the Leukemia Society of America, Leukemia Research Fund, U.K》 - 2023,37(6) - 1204～1215 - 共12页 - 被引量：3

摘要：Mismatch repair (MMR) deficiency has been linked to thiopurine resistance and hypermutation in relapsed acute lymphoblastic leukemia (ALL). However, the repair mechanism of thiopurine-induced DNA dama...

关键词： BASE EXCISION-REPAIR | THIOPURINE RESISTANCE | OLEANOLIC ACID | CELLS | THERAPY | 6-THIOGUANINE | TRANSLESION | INHIBITION | MECHANISMS | DAMAGE

9. Genomic landscape of Down syndrome-associated acute lymphoblastic leukemia NSTL国家科技图书文献中心

Li, Zhenhua | Chang, Ti-Cheng ... - 《Blood: The Journal of the American Society of Hematology》 - 2023,142(2) - 172～184 - 共13页 - 被引量：3

摘要：Trisomy 21, the genetic cause of Down syndrome (DS), is the most common congenital chromosomal anomaly. It is associated with a 20-fold increased risk of acute lymphoblastic leukemia (ALL) during chil...

关键词： DOWN-SYNDROME | B-PROGENITOR | CRLF2 | TRANSLOCATIONS | DISEASE | IGF2BP1 | REARRANGEMENT | EXPRESSION | CANCER | IKZF1

10. Development of a seven-region lumped parameter nonlinear dynamic model for U-tube recirculation nuclear steam generator EI 工程索引 SCIE Web of Science核心 NSTL国家科技图书文献中心

Zhong, Xianping | Guo, Pengya ... - 《Annals of nuclear energy》 - 2022,174(Sep.) - 109190.1～109190.10 - 共10页 - 被引量：1

摘要：A lumped parameter nonlinear dynamic model for U-tube recirculation steam generator (UTSG) transient analysis is developed based on the conservation laws of mass, momentum and energy. UTSG is modeled ...