NSTL国家科技图书文献中心

1. Breast cancer surveillance for epithelial ovarian cancer patients with BRCA1 and BRCA2 pathogenic variants: a single-center retrospective study NSTL国家科技图书文献中心

Hasegawa-Minato, Jun... | Tochigi, Mikako ... - 《Japanese journal of clinical oncology.》 - 2025,55(5) - 484～489 - 共6页

摘要：Objectives To identify a method for breast cancer (BC) surveillance in patients with epithelial ovarian cancer (EOC) with germline BRCA1/2 pathogenic variants (gBRCA1/2m) and the incidence of BC after...

关键词： breast cancer | ovarian cancer | surveillance | BRCA | MRI

2. Coexisting germline variants of MLH1 and MSH6 in a patient with Lynch syndrome who had uterine and ovarian cancer NSTL国家科技图书文献中心

Umegaki, Sho | Takahashi, Masanobu ... - 《International Cancer Conference Journal》 - 2025,14(2) - 171 ～176 - 共6页

摘要：Lynch syndrome is an autosomal dominant disorder caused by a heterozygous pathogenic germline variant in mismatch repair (MMR) genes including MLH1, MSH2, MSH6, PMS2, and EPCAM. This disease often cau...

关键词： Lynch syndrome | MLH1 | MSH6 | BRCA1 | BRCA2

3. Long-Term and Short-Interval Assessment of Self-Reported Urinary and Sexual Functions after Nerve-Sparing Radical Hysterectomy: A Prospective Cohort Study NSTL国家科技图书文献中心

Ishibashi, Masumi | Niikura, Hitoshi ... - 《The Tohoku Journal of Experimental Medicine》 - 2024,263(1) - 1～9 - 共9页

摘要：The aim of this study was to determine the impact of nerve preservation confirmed by intraoperative electrical stimulation (IES) on subjective symptoms of urinary and sexual function in uterine cervic...

关键词： bladder function | intraoperative electrical stimulation | nerve-preserving radical hysterectomy | sexual function | uterine cervical cancer | INTRAOPERATIVE ELECTRICAL-STIMULATION | QUALITY-OF-LIFE | CERVICAL-CANCER | BLADDER FUNCTION | OUTCOMES...

4. A qualitative systematic review of the significance of adjuvant therapy in patients with low-risk endometrial cancer presenting positive peritoneal cytology: a relevant study to the guideline update for endometrial cancer by the Japan society of gynecologic oncology guideline committee NSTL国家科技图书文献中心

Shigeta, Shogo | Konno, Yosuke ... - 《Japanese journal of clinical oncology.》 - 2024,54(2) - 217～220 - 共4页 - 被引量：1

摘要：In association with an update of the Japan Society of Gynecologic Oncology clinical practice guidelines for endometrial cancer in 2023, a systematic review was conducted about the therapeutic benefit ...

关键词： chemotherapy | adjuvant | cytology | endometrial neoplasms | systematic review | prognosis | PROGNOSTIC-FACTORS | CARCINOMA | SURVIVAL

5. Lenvatinib plus Pembrolizumab Combination Therapy for Advanced or Recurrent Endometrial Cancer: A Single-Center, Retrospective Analysis NSTL国家科技图书文献中心

Tochigi, Mikako | Shigeta, Shogo ... - 《The Tohoku Journal of Experimental Medicine》 - 2024,262(2) - 85～95 - 共11页

摘要：A multi-kinase inhibitor, lenvatinib, plus an immune checkpoint inhibitor, pembrolizumab, became a viable therapeutic option for advanced or recurrent endometrial cancer in Japan by the end of 2021. T...

关键词： combination therapy | endometrial cancer | lenvatinib | pembrolizumab | relative dose intensity | PHASE-III TRIAL | GYNECOLOGIC-ONCOLOGY-GROUP | CARCINOMA | CISPLATIN | DOXORUBICIN...

6. Pretreatment systemic inflammatory markers predict survival in endometrial cancer: A Japanese Gynecologic Oncology Group 2043 exploratory data analysis NSTL国家科技图书文献中心

Nishio, Shin | Murotani, Kenta ... - 《Gynecologic Oncology》 - 2024,181 - 46～53 - 共8页

摘要：Objective. We investigated whether pretreatment systemic inflammatory markers are associated with sur-vival outcomes in patients with endometrial cancer (EC).Methods. Data from the Japanese Gynecologi...

关键词： Endometrial cancer | Neutrophil-to-lymphocyte ratio | Hemoglobin albumin lymphocyte and platelet (HALP) score

7. Assessing the Significance of Lymphadenectomy in Older Patients with Stage I Endometrial Cancer: A Single-Center, Retrospective Cohort Study NSTL国家科技图书文献中心

Hasegawa-Minato, Jun... | Shigeta, Shogo ... - 《The Tohoku Journal of Experimental Medicine》 - 2023,261(1) - 83～93 - 共11页 - 被引量：1

摘要：Advantages of lymphadenectomy for early stage endometrial cancer remain controversial. Lymphadenectomy had been routinely omitted for patients aged >= 70 years at our institute if lymph node metastasi...

关键词： endometrial neoplasm | lymph node excision | older individuals | prognosis | survival | LYMPH-NODE METASTASIS | LYMPHVASCULAR SPACE INVOLVEMENT | PARAAORTIC LYMPHADENECTOMY | PELVIC LYMPHADENECTOMY | RISK-FACTORS...

8. Retrospective analysis of local recurrence pattern by computed tomography image-guided intracavitary and interstitial brachytherapy for locally advanced cervical cancer in a single Japanese institution NSTL国家科技图书文献中心

Umezawa, Rei | Tokunaga, Hideki ... - 《Brachytherapy》 - 2023,22(4) - 477～486 - 共10页

摘要：PURPOSE: The purpose of this study was to investigate the treatment results with focus on local control (LC) by computed tomography (CT)-guided intracavity brachytherapy and interstitial brachytherapy...

关键词： Uterine cervical cancer | Intracavitary brachytherapy | Interstitial brachytherapy | Image-guided brachytherapy | Local control | DOSE-RATE BRACHYTHERAPY | ADAPTIVE BRACHYTHERAPY | RADIATION-THERAPY | ONCOLOGY-GROUP | TREATMENT TIME...

9. Veliparib with frontline chemotherapy and as maintenance in Japanese women with ovarian cancer: a subanalysis of efficacy, safety, and antiemetic use in the phase 3 VELIA trial NSTL国家科技图书文献中心

Mizuno, Mika | Ito, Kimihiko ... - 《International journal of clinical oncology》 - 2023,28(1) - 163～174 - 共12页 - 被引量：1

摘要：Background The phase 3 VELIA trial evaluated veliparib with carboplatin/paclitaxel and as maintenance in patients with high-grade serous ovarian carcinoma. Methods Patients with previously untreated s...

关键词： Ovarian cancer | PARP inhibitor | Veliparib | VELIA | Antiemetics | Japanese | CELL LUNG-CANCER | EPITHELIAL OVARIAN | FALLOPIAN-TUBE | FROZEN-SECTION...

10. Clinical issues of surgery for uterine endometrial cancer in Japan SCIE Web of Science核心 NSTL国家科技图书文献中心

Nagai, Tomoyuki | Shimada, Muneaki ... - 《Japanese journal of clinical oncology.》 - 2022,52(4) - 346～352 - 共7页

摘要：Objective The mainstay of treatment for uterine endometrial cancer is surgery, and recurrent-risk cases require multidisciplinary treatment, including surgery, chemotherapy and radiation therapy. Meth...

关键词： endometrial neoplasms | surgery | lymphadenectomy | sentinel lymph node | biomarker | LYMPH-NODE METASTASIS | TOTAL LAPAROSCOPIC HYSTERECTOMY | TOTAL ABDOMINAL HYSTERECTOMY | MINIMALLY INVASIVE SURGERY | PARAAORTIC LYMPHADENECTOMY...

摘要：Objectives To identify a method for breast cancer (BC) surveillance in patients with epithelial ovarian cancer (EOC) with germline BRCA1/2 pathogenic variants (gBRCA1/2m) and the incidence of BC after...

关键词： breast cancer | ovarian cancer | surveillance | BRCA | MRI

摘要：Lynch syndrome is an autosomal dominant disorder caused by a heterozygous pathogenic germline variant in mismatch repair (MMR) genes including MLH1, MSH2, MSH6, PMS2, and EPCAM. This disease often cau...

关键词： Lynch syndrome | MLH1 | MSH6 | BRCA1 | BRCA2

摘要：The aim of this study was to determine the impact of nerve preservation confirmed by intraoperative electrical stimulation (IES) on subjective symptoms of urinary and sexual function in uterine cervic...

关键词： bladder function | intraoperative electrical stimulation | nerve-preserving radical hysterectomy | sexual function | uterine cervical cancer | INTRAOPERATIVE ELECTRICAL-STIMULATION | QUALITY-OF-LIFE | CERVICAL-CANCER | BLADDER FUNCTION | OUTCOMES...

摘要：In association with an update of the Japan Society of Gynecologic Oncology clinical practice guidelines for endometrial cancer in 2023, a systematic review was conducted about the therapeutic benefit ...

关键词： chemotherapy | adjuvant | cytology | endometrial neoplasms | systematic review | prognosis | PROGNOSTIC-FACTORS | CARCINOMA | SURVIVAL

摘要：A multi-kinase inhibitor, lenvatinib, plus an immune checkpoint inhibitor, pembrolizumab, became a viable therapeutic option for advanced or recurrent endometrial cancer in Japan by the end of 2021. T...

关键词： combination therapy | endometrial cancer | lenvatinib | pembrolizumab | relative dose intensity | PHASE-III TRIAL | GYNECOLOGIC-ONCOLOGY-GROUP | CARCINOMA | CISPLATIN | DOXORUBICIN...

摘要：Objective. We investigated whether pretreatment systemic inflammatory markers are associated with sur-vival outcomes in patients with endometrial cancer (EC).Methods. Data from the Japanese Gynecologi...

关键词： Endometrial cancer | Neutrophil-to-lymphocyte ratio | Hemoglobin albumin lymphocyte and platelet (HALP) score

摘要：Advantages of lymphadenectomy for early stage endometrial cancer remain controversial. Lymphadenectomy had been routinely omitted for patients aged >= 70 years at our institute if lymph node metastasi...

关键词： endometrial neoplasm | lymph node excision | older individuals | prognosis | survival | LYMPH-NODE METASTASIS | LYMPHVASCULAR SPACE INVOLVEMENT | PARAAORTIC LYMPHADENECTOMY | PELVIC LYMPHADENECTOMY | RISK-FACTORS...

摘要：PURPOSE: The purpose of this study was to investigate the treatment results with focus on local control (LC) by computed tomography (CT)-guided intracavity brachytherapy and interstitial brachytherapy...

关键词： Uterine cervical cancer | Intracavitary brachytherapy | Interstitial brachytherapy | Image-guided brachytherapy | Local control | DOSE-RATE BRACHYTHERAPY | ADAPTIVE BRACHYTHERAPY | RADIATION-THERAPY | ONCOLOGY-GROUP | TREATMENT TIME...

摘要：Background The phase 3 VELIA trial evaluated veliparib with carboplatin/paclitaxel and as maintenance in patients with high-grade serous ovarian carcinoma. Methods Patients with previously untreated s...

关键词： Ovarian cancer | PARP inhibitor | Veliparib | VELIA | Antiemetics | Japanese | CELL LUNG-CANCER | EPITHELIAL OVARIAN | FALLOPIAN-TUBE | FROZEN-SECTION...

摘要：Objective The mainstay of treatment for uterine endometrial cancer is surgery, and recurrent-risk cases require multidisciplinary treatment, including surgery, chemotherapy and radiation therapy. Meth...

关键词： endometrial neoplasms | surgery | lymphadenectomy | sentinel lymph node | biomarker | LYMPH-NODE METASTASIS | TOTAL LAPAROSCOPIC HYSTERECTOMY | TOTAL ABDOMINAL HYSTERECTOMY | MINIMALLY INVASIVE SURGERY | PARAAORTIC LYMPHADENECTOMY...

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