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1. Diabetes and cardiovascular disease in older adults NSTL国家科技图书文献中心

Anika Bilal |  Richard Pratley -  《Annals of the New York Academy of Sciences》 - 2025,1543(Jan.) - 42~67 - 共26页

摘要:Abstract An aging population combined with a rapidly increasing prevalence of diabetes foreshadows a global epidemic of cardiovascular and kidney disease that threatens to halt improvements in life an...
关键词: cardiovascular disease |  chronic kidney disease |  diabetes |  heart failure |  newer antihyperglycemic drugs |  older adults

2. Cardiovascular outcomes with semaglutide by severity of chronic kidney disease in type 2 diabetes: the FLOW trial NSTL国家科技图书文献中心

Kenneth W Mahaffey |  Katherine R Tuttle... -  《European Heart Journal》 - 2025,46(12) - 1096~1108 - 共13页

摘要:Background and aims: In the FLOW trial, semaglutide reduced the risks of kidney and cardiovascular (CV) outcomes and death in participants with type 2 diabetes and chronic kidney disease (CKD). These ...
关键词: Cardiovascular outcomes; Chronic kidney disease; Semaglutide; Type 2 diabetes.

3. Safety and tolerability of semaglutide across the SUSTAIN and PIONEER phase IIIa clinical trial programmes NSTL国家科技图书文献中心

Vanita R. Aroda |  Umut Erhan... -  《Diabetes, obesity & metabolism.》 - 2023,25(5) - 1385~1397 - 共13页 - 被引量:5

摘要:Abstract Aim Glucagon‐like peptide‐1 receptor agonists improve glycaemic control: some are now available as oral and subcutaneous formulations, and some have indications for reducing cardiovascular ri...
关键词: antidiabetic drug |  GLP‐1 |  phase III study |  randomized trial |  type 2 diabetes

4. Prototype of an evidence-based tool to aid individualized treatment for type 2 diabetes SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

JohnB. Buse |  Ingrid Holst... -  《Diabetes, obesity & metabolism.》 - 2021,23(7) - 1666~1671 - 共6页

摘要:Data-driven tools are needed to inform individualized treatment decisions for people with type 2 diabetes (T2D). To show how treatment might be individualized, an interactive outline tool was develope...
关键词: antidiabes drug |  type 2 diabetes

5. Efficacy and safety of ertugliflozin in older patients with type 2 diabetes: A pooled analysis of phase III studies SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Richard Pratley |  Samuel Dagogo-Jack... -  《Diabetes, obesity & metabolism.》 - 2020,22(12) - 2276~2286 - 共11页

摘要:Aim: To assess the efficacy and safety of ertugliflozin in older patients with type 2 diabetes (T2D).Materials and methods: This is a post hoc analysis of patients with T2D aged less than 65 years and...
关键词: antidiabetic drug |  diabetes complications |  glycaemic control |  observational study |  SGLT2 inhibitor |  type 2 diabetes

6. Impaired Awareness of Hypoglycemia in Older Adults With Type 1 Diabetes: A Post Hoc Analysis of the WISDM Study NSTL国家科技图书文献中心

Anika Bilal |  Fanchao Yi... -  《Diabetes care》 - 2024,47(7) - 1202~1210 - 共9页

摘要:Objective: Up to one-third of older adults with type 1 diabetes experience impaired awareness of hypoglycemia (IAH), yet the factors associated with IAH remain underexplored in older adults. Research ...

8. Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes NSTL国家科技图书文献中心

Vlado Perkovic |  Katherine R. Tuttle... -  《The New England journal of medicine》 - 2024,391(2) - 109~121 - 共13页

摘要:BACKGROUND:Patients with type 2 diabetes and chronic kidney disease are at high risk for kidney failure, cardiovascular events, and death. Whether treatment with semaglutide would mitigate these risks...

9. Ertugliflozin and Slope of Chronic eGFR: Prespecifsed Analyses from the Randomized VERTIS CV Trial SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

David Z.I. Cherney |  Francesco Cosentino... -  《Clinical journal of the American Society of Nephrology: CJASN》 - 2021,16(9) - 1345~1354 - 共10页 - 被引量:22

摘要:Background and objectives A reduction in the rate of eGFR decline, with preservation of >0.75 ml/rnin per 1.73 m~2 per year, has been proposed as a surrogate for kidney disease progression. We report ...

10. Efficacy, safety and cardiovascular outcomes of once-daily oral semaglutide in patients with type 2 diabetes: The PIONEER programme SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Tina K.Thethi |  Richard Pratley... -  《Diabetes, obesity & metabolism.》 - 2020,22(8) - 1263~1277 - 共15页

摘要:Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are recommended for glycaemic management in patients with type 2 diabetes (T2D). Oral semaglutide, the first oral GLP-1RA, has recently been approv...
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