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1. Expression profiles of antiviral response genes in chicken bursal cells stimulated with Toll-like receptor ligands SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Alkie, Tamiru Negash |  Paul, Michael St.... -  《Veterinary Immunology and Immunopathology》 - 2015,163(3/4) - 157~163 - 共7页 - 被引量:9

摘要:Cells of the adaptive immune system express Toll-like receptors (TLRs) and are able to respond to TLR ligands. With this in mind, the goal of the current study was to determine the expression of antiv...
关键词: Antiviral genes |  Chicken |  Bursal cells |  Toll-like receptor ligands

2. Deficiency of MALT1 Paracaspase Activity Results in Unbalanced Regulatory and Effector T and B Cell Responses Leading to Multiorgan Inflammation SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Bornancin, Frederic |  Renner, Florian... -  《The Journal of Immunology: Official Journal of the American Association of Immunologists》 - 2015,194(8) - 3723~3734 - 共12页 - 被引量:94

摘要:The paracaspase MALT1 plays an important role in immune receptor-driven signaling pathways leading to NF-kappa B activation. MALT1 promotes signaling by acting as a scaffold, recruiting downstream sig...

3. Ex vivo activation of the GCN2 pathway metabolically reprograms T cells, leading to enhanced adoptive cell therapy

Paul, Michael St. |  Saibil, Samuel D.... -  《Cell Reports Medicine》 - 2024,5(3) - 共17页 - 被引量:3

摘要:The manipulation of T cell metabolism to enhance anti -tumor activity is an area of active investigation. Here, we report that activating the amino acid starvation response in effector CD8 + T cells e...
关键词: KINASE GCN2 |  MEMORY |  AUTOPHAGY |  EXPRESSION |  INDUCTION |  SURVIVAL |  FITNESS
检索条件作者:Paul, Michael St.

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