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1. A novel fungal gene regulation system based on inducible VPR-dCas9 and nucleosome map-guided sgRNA positioning SCOPUS Scopus数据库 SCIE Web of Science核心 EI 工程索引 NSTL国家科技图书文献中心

Schuller, Andreas | Wolansky, Lisa ... - 《Applied Microbiology and Biotechnology》 - 2020,104(22) - 9801～9822 - 共22页

摘要：Programmable transcriptional regulation is a powerful tool to study gene functions. Current methods to selectively regulate target genes are mainly based on promoter exchange or on overexpressing tran...

关键词： dCas9 gene activation | Programmable transcriptional regulator | Aspergillus | Biosynthetic gene clusters | Genome-wide nucleosome positioning map

2. Regulation of a novel Fusarium cytokinin in Fusarium pseudograminearum SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Blum, Ailisa | Benfield, Aurelie H.... - 《Fungal Biology》 - 2019,123(3) - 255～266 - 共12页

摘要：Fusarium pseudograminearum is an agronomically important fungus, which infects many crop plants, including wheat, where it causes Fusarium crown rot. Like many other fungi, the Fusarium genus produces...

关键词： Hormone | Wheat | Cereal | Mycotoxin | GFP | Pathogen

3. Mechanistic Characterisation of Two Sesquiterpene Cyclases from the Plant Pathogenic Fungus Fusarium fujikuroi NSTL国家科技图书文献中心

Burkhardt, Immo | Siemon, Thomas ... - 《Angewandte Chemie》 - 2016,55(30) - 8748～8751 - 共4页

摘要：Two sesquiterpene cyclases from Fusarium fujikuroi were expressed in Escherichia coli and purified. The first enzyme was inactive because of a critical mutation, but activity was restored by sequence ...

关键词： enzyme mechanisms | Fusarium fujikuroi | isotopic labelling | NMR spectroscopy | terpenes

4. Genetic engineering, high resolution mass spectrometry and nuclear magnetic resonance spectroscopy elucidate the bikaverin biosynthetic pathway in Fusarium fujikuroi SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Arndt, Birgit | Studt, Lena ... - 《Fungal Genetics and Biology》 - 2015,84 - 26～36 - 共11页

摘要：Secondary metabolites of filamentous fungi can be highly bioactive, ranging from antibiotic to cancerogenic properties. In this study we were able to identify a new, yet unknown metabolite produced by...

关键词： Fusarium | Genomics | Bikaverin | Biosynthesis | Natural products | Mass spectrometry | NMR spectroscopy

5. Cyclic, Hydrophobic Hexapeptide Fusahexin Is the Product of a Nonribosomal Peptide Synthetase in Fusarium graminearum SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Westphal, Klaus R. | Bachleitner, Simone ... - 《Journal of natural products》 - 2021,84(8) - 2070～2080 - 共11页

摘要：The plant pathogenic fungus Fusarium graminearum is known to produce a wide array of secondary metabolites during plant infection. This includes several nonribosomal peptides. Recently, the fusaoctaxi...

6. Sound of silence: the beauvericin cluster in Fusarium fujikuroi is controlled by cluster-specific and global regulators mediated by H3K27 modification NSTL国家科技图书文献中心

Niehaus, Eva-Maria | Studt, Lena ... - 《Environmental microbiology》 - 2016,18(11) - 4282～4302 - 共21页

摘要：In this study, we compared the secondary metabolite profile of Fusarium fujikuroi and the histone deacetylase mutant Delta HDA1. We identified a novel peak in Delta HDA1, which was identified as beauv...

7. Knock-down of the methyltransferase Kmt6 relieves H3K27me3 and results in induction of cryptic and otherwise silent secondary metabolite gene clusters in Fusarium fujikuroi NSTL国家科技图书文献中心

Studt, Lena | Roesler, Sarah M.... - 《Environmental microbiology》 - 2016,18(11) - 4037～4054 - 共18页

摘要：Filamentous fungi produce a vast array of secondary metabolites (SMs) and some play a role in agriculture or pharmacology. Sequencing of the rice pathogen Fusarium fujikuroi revealed the presence of f...

8. The global regulator FfSge1 is required for expression of secondary metabolite gene clusters but not for pathogenicity in Fusarium fujikuroi SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Michielse, Caroline ... | Studt, Lena ... - 《Environmental microbiology》 - 2015,17(8) - 2690～2708 - 共19页

摘要：The plant pathogenic fungus Fusarium fujikuroi is the causal agent of bakanae disease on rice due to its ability to produce gibberellins. Besides these phytohormones, F.fujikuroi is able to produce se...

9. Secondary Metabolite Gene Regulation in Mycotoxigenic Fusarium Species: A Focus on Chromatin

Atanasoff-Kardjalief... | Studt, Lena - 《toxins》 - 2022,14(2) - 共29页

摘要：Fusarium is a species-rich group of mycotoxigenic plant pathogens that ranks as one of the most economically important fungal genera in the world. During growth and infection, they are able to produce...

关键词： fungal secondary metabolism | mycotoxins | histone post-translational modifications (histone marks) | transcription factors (TFs) | gene expression | GIBBERELLIN BIOSYNTHETIC-PATHWAY | HISTONE ACETYLTRANSFERASE | POLYKETIDE SYNTHASE | DNA METHYLATION | FUNCTIONAL-CHARACTERIZATION...

10. Biosynthesis of Fusapyrone Depends on the H3K9 Methyltransferase, FmKmt1, in Fusarium mangiferae

Atanasoff-Kardjalief... | Luenne, Friederike ... - 《Frontiers in fungal biology》 - 2021,2 - 共23页

摘要：The phytopathogenic fungus Fusarium mangiferae belongs to the Fusarium fujikuroi species complex (FFSC). Members of this group cause a wide spectrum of devastating diseases on diverse agricultural cro...

关键词： heterochromatin | histone PTMs | Fusarium mangiferae | Fusarium fujikuroi species complex | secondary metabolism | fusapyrone | deoxyfusapyrone | MANGO FLOWER MALFORMATION | 4'-PHOSPHOPANTETHEINYL TRANSFERASE | POLYKETIDE SYNTHASES...