NSTL国家科技图书文献中心

1. Stimulus effects of extremely low-frequency electric field exposure on calcium oscillations in a human cortical spheroid NSTL国家科技图书文献中心

Saito, Atsushi | Shiina, Takeo ... - 《Bioelectromagnetics.》 - 2025,46(1) - e22521～e22521 - 共13页

摘要：High-intensity, low-frequency (1 Hz to 100 kHz) electric and magnetic fields (EF and MF) cause electrical excitation of the nervous system via an induced EF (iEF) in living tissue. However, the biolog...

关键词： electric field | human cortical spheroid | low-frequency | nerve stimulation | neuronal activity

2. Real-world data on combination treatment with bedaquiline in patients with multidrug-resistant pulmonary tuberculosis in Japan: An interim analysis of post-marketing surveillance NSTL国家科技图书文献中心

Nakaya, Mako | Kamishima, Manami ... - 《Journal of infection and chemotherapy》 - 2025,31(4) - Article 102661～Article 102661 - 共8页

摘要：Background: An observational post-marketing surveillance (PMS) is being conducted to evaluate the long-term safety and effectiveness of bedaquiline as part of combination therapies in treating pulmona...

关键词： Bedaquiline | Japanese | Multidrug-resistant tuberculosis | Post-marketing surveillance | QT interval prolongation

3. Unfolded protein response modulates Tyrosinase levels and melanin production during melanogenesis NSTL国家科技图书文献中心

Yamazaki, Akari | Omura, Issei ... - 《Journal of dermatological science》 - 2025,117(2) - 36～44 - 共9页

摘要：Background: Melanocytes protect the body from ultraviolet radiation by synthesizing melanin. Tyrosinase, a key enzyme in melanin production, accumulates in the endoplasmic reticulum (ER) during melani...

关键词： Melanin production | Tyrosinase | Pigmentation disorders | Endoplasmic reticulum stress | Unfolded protein response

4. CREB3L1 /OASIS: cell cycle regulator and tumor suppressor NSTL国家科技图书文献中心

Saito, Atsushi | Omura, Issei ... - 《The FEBS journal》 - 2024,291(22) - 4853～4866 - 共14页

摘要：Cell cycle checkpoints detect DNA errors, eventually arresting the cell cycle to promote DNA repair. Failure of such cell cycle arrest causes aberrant cell proliferation, promoting the pathogenesis of...

关键词： astrocyte | cell cycle arrest | DNA damage | glioblastoma | methylation | OASIS | p21 | p53 | tumor suppressor | tumorigenesis

5. Physical Properties of Background Aerosols and Cloud Condensation Nuclei Measured in Kochi City in June 2010 and Its Implication for Planned and Inadvertent Cloud Modification NSTL国家科技图书文献中心

Yamashita, Katsuya | Kuo, Wei-Chen ... - 《Journal of the Meteorological Society of Japan》 - 2024,102(3) - 353～363 - 共11页

摘要：Background (BG) aerosol particles (APs) acting as cloud condensation nuclei (CCN) and/or ice nucleating particles (INPs) influence short-range precipitation forecasts and climate change projections by...

关键词： cloud condensation nuclei | characteristics of atmospheric aerosols | hygroscopic seeding | weather modification | SEEDING CONVECTIVE CLOUDS | PART 1 | HYGROSCOPICITY | NUCLEATION | PARTICLES | GROWTH...

6. Social defeat stress enhances the rewarding effects of cocaine through alpha1A adrenoceptors in the medial prefrontal cortex of mice NSTL国家科技图书文献中心

Saito, Atsushi | Murata, Haruka ... - 《Neuropharmacology》 - 2024,242 - 109757～109757 - 共6页

摘要：Various stressors potentiate the rewarding effects of cocaine and contribute to cocaine cravings. However, it remains unclear whether psychosocial stress enhances the rewarding effects of cocaine. Acc...

关键词： Social defeat stress | Noradrenaline | Cocaine | Conditioned place preference | alpha(1A) adrenoceptor | CONDITIONED PLACE PREFERENCE | CORTICOTROPIN-RELEASING-FACTOR | OBJECT RECOGNITION MEMORY | RECEPTOR MESSENGER-RNA | INDUCED REINSTATEMENT...

7. Periodontal regenerative therapy using recombinant human fibroblast growth factor (rhFGF)-2 in combination with carbonate apatite granules or rhFGF-2 alone: 12-month randomized controlled trial NSTL国家科技图书文献中心

Imamura, Kentaro | Yoshida, Wataru ... - 《Clinical oral investigations.》 - 2024,28(11) - Article: 574～Article: 574 - 共6页 - 被引量：1

摘要：Objectives This randomized controlled trial compared the outcomes of recombinant human fibroblast growth factor (rhFGF)-2 plus carbonate apatite (CO(3)Ap) granules with rhFGF-2 alone in the treatment ...

关键词： Fibroblast growth factor-2 | Carbonate apatite granules | Patient-reported outcome | Periodontal regeneration | Bone graft | QUALITY-OF-LIFE | INTRABONY DEFECTS | CLINICAL-OUTCOMES | SURGICAL APPROACH | BOVINE BONE...

8. A retrospective study of prognostic factors and prostate-specific antigen dynamics in Japanese patients with metastatic hormone-sensitive prostate cancer who received combined androgen blockade therapy with bicalutamide NSTL国家科技图书文献中心

Tashiro, Yu | Akamatsu, Shusuke ... - 《International journal of clinical oncology》 - 2024,29(10) - 1564～1573 - 共10页

摘要：Background This retrospective observational study explored the therapeutic potential of combined androgen blockade (CAB) with bicalutamide (Bic-CAB) as an initial treatment for metastatic hormone-sens...

关键词： Bicalutamide | Combined androgen blockage | Japan | Metastatic hormone-sensitive prostate cancer

9. Nuclear GAPDH in cortical microglia mediates cellular stress-induced cognitive inflexibility NSTL国家科技图书文献中心

Ramos, Adriana | Ishizuka, Koko ... - 《Molecular psychiatry》 - 2024,29(10) - 2967～2978 - 共12页 - 被引量：1

摘要：We report a mechanism that underlies stress-induced cognitive inflexibility at the molecular level. In a mouse model under subacute cellular stress in which deficits in rule shifting tasks were elicit...

关键词： SUPEROXIDE DISMUTASE-1 SOD1 | CEREBROSPINAL-FLUID | EXECUTIVE FUNCTION | ACTIVATION | SCHIZOPHRENIA | INFLAMMATION | FLEXIBILITY | DEFICITS | DEATH | NEUROPROTECTION

10. The effects of dental visits on the occurrence of acute hospitalization for systemic diseases among patients aged 75 years or older: A propensity score-matched study NSTL国家科技图书文献中心

Mitsutake, Seigo | Ishizaki, Tatsuro ... - 《Archives of Gerontology and Geriatrics: An International Journal Integrating Experimental, Clinical and Social Studies on Ageing》 - 2023,107 - 104876～104876 - 共7页 - 被引量：1

摘要：Background: Although several studies examined the association between oral status and the risk of systemic diseases, few have examined whether dental visits affect the occurrence of acute hospitalizat...

关键词： Admission | Big data | Dental care | Health services for the aged | PERIODONTAL-DISEASE | RISK-FACTORS | ORAL CARE | PNEUMONIA | ASSOCIATION | MORTALITY...