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1. Development of an 18 F-labeled 5-aroylindole derivative for histone deacetylase 6 imaging in spinocerebellar ataxia NSTL国家科技图书文献中心

Yu, Hung-Man |  Lin, Kun-Liang... -  《Applied radiation and isotopes》 - 2025,217 - 共6页

摘要:Histone deacetylase 6 (HDAC6) is an enzyme crucial in epigenetic regulation and protein degradation, with implications in various cancers and neurodegenerative disorders. While HDAC6 is recognized as ...
关键词: Histone deacetylase 6 |  Spinocerebellar ataxia |  Positron emission tomography |  Epigenetic |  Fluorine-18

2. A novel 111indium-labeled dual carbonic anhydrase 9-targeted probe as a potential SPECT imaging radiotracer for detection of hypoxic colorectal cancer cells SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Guan, Siao-Syun |  Wu, Cheng-Tien... -  《European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V》 - 2021,168 - 38~52 - 共15页 - 被引量:1

摘要:Tumor hypoxia is a common feature in colorectal cancer (CRC), and is associated with resistance to radiotherapy and chemotherapy. Thus, a specifically targeted probe for the detection of hypoxic CRC c...
关键词: Colorectal cancer |  Tumor hypoxia |  Carbonic anhydrase 9-targeted probe |  Indium-111 label |  SPECT imaging

3. Ga-68-labelled NOTA-RGD-GE11 peptide for dual integrin and EGFR-targeted tumour imaging SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Chen, Chien-Jen |  Chan, Chen-Hsin... -  《Nuclear Medicine and Biology》 - 2019,68/69 - 22~30 - 共9页 - 被引量:13

摘要:Introduction: Multiple peptide receptors are co-expressed in many types of cancers. Arg-Gly-Asp (RGD) and GE11 peptides specifically target integrin alpha(v)beta(3)( )and EGFR, respectively. Recently,...
关键词: Heterodimer peptide |  Integrin alpha(v)beta(3) |  EGFR |  Ga-68 |  PET imaging

4. Power Flow and Generator-Converter Schemes Studies in Ship MVDC Distribution Systems NSTL国家科技图书文献中心

Su, Chun-Lien |  Lin, Kun-Liang... -  《IEEE Transactions on Industry Applications》 - 2016,52(1) - 50~59 - 共10页 - 被引量:15

摘要:The medium-voltage dc (MVDC) distribution system is a new shipboard power distribution technology that has been extensively discussed and studied by many shipbuilding corporations and ship-owners in r...
关键词: Industrial power systems |  load flow analysis |  marine vehicle power systems |  medium-voltage dc (MVDC) converter |  power system planning

5. Synthesis of Ga-68-labeled NOTA-RGD-GE11 heterodimeric peptide for dual integrin and epidermal growth factor receptor-targeted tumor imaging SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Yu, Hung-Man |  Chen, Jyun-Hong... -  《Journal of labelled compounds & radiopharmaceuticals.》 - 2015,58(7) - 299~303 - 共5页 - 被引量:14

摘要:Radiolabeled Arg-Gly-Asp (RGD) peptide analogs have been extensively studied for (v3) integrin-targeted angiogenesis imaging. According to recently presented evidence, the dodecapeptide GE11 has high ...
关键词: heterodimer peptide |  epidermal growth factor receptor (EGFR) |  integrin (v3) |  GE11 |  RGD |  positron emission tomography (PET) |  Ga-68

6. Corroboration of Zn(ii)-Mg(ii)-tertiary structure interplays essential for the optimal catalysis of a phosphorothiolate thiolesterase ribozyme SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Wang, Tzu-Pin |  Su, Yu-Chih... -  《RSC Advances》 - 2018,8(57) - 32775~32793 - 共19页

摘要:The TW17 ribozyme, a catalytic RNA selected from a pool of artificial RNA, is specific for the Zn2+-dependent hydrolysis of a phosphorothiolate thiolester bond. Here, we describe the organic synthesis...
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