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1. Single-Administration Long-Acting Microarray Patch with Ultrahigh Loading Capacity and Multiple Releases of Thermally Stable Antibodies NSTL国家科技图书文献中心

Tran, Khanh T. M. |  Le, Thinh T.... -  《Molecular pharmaceutics》 - 2023,20(5) - 2352~2361 - 共10页 - 被引量:6

摘要:Current antibody (Ab) therapies require development of stable formulations and an optimal delivery system. Here, we present a new strategy to create a single-administration long-lasting Ab-delivery mi...
关键词: microarray patch |  fabrications |  therapeutic antibodies |  protein stabilization |  long-acting delivery |  DISSOLVING MICRONEEDLES |  SUSTAINED-RELEASE |  DRUG |  IGG |  DELIVERY...

2. Piezoelectric Nanofiber Membrane for Reusable, Stable, and Highly Functional Face Mask Filter with Long-Term Biodegradability SCIE Web of Science核心 EI 工程索引 NSTL国家科技图书文献中心

Le, Thinh T. |  Curry, Eli J.... -  《Advanced functional materials》 - 2022,32(20) - 2113040.1~2113040.13 - 共13页 - 被引量:49

摘要:The emergence of the SARS-CoV-2 pandemic and airborne particulate matter (PM) pollution has led to remarkably high demand for face masks. However, conventional respirators are intended for single use ...
关键词: biodegradable |  facemasks |  piezoelectric |  PLLA nanofibers |  reusable

3. Biodegradable nanofiber bone-tissue scaffold as remotely-controlled and self-powering electrical stimulator SCOPUS Scopus数据库 EI 工程索引 SCIE Web of Science核心 NSTL国家科技图书文献中心

Das, Ritopa |  Curry, Eli J.... -  《Nano Energy》 - 2020,76 - 共11页 - 被引量:64

摘要:Electrical stimulation (ES) has been shown to induce and enhance bone regeneration. By combining this treatment with tissue-engineering approaches (which rely on biomaterial scaffolds to construct art...
关键词: Biodegradable piezoelectric nanofibers |  Ultrasound |  Electrical stimulation |  Bone regeneration |  Tissue engineering

4. Biodegradable nanofiber-based piezoelectric transducer SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Curry, Eli J. |  Le, Thinh T.... -  《Proceedings of the National Academy of Sciences of the United States of America.》 - 2020,117(1) - 214~220 - 共7页 - 被引量:115

摘要:

Piezoelectric materials, a type of "smart" material that generates electricity while deforming and vice versa, have been used extensively for many important implantable m...

关键词: biodegradable |  piezoelectric |  PLLA |  pressure sensors |  ultrasound transducer |  FOCUSED ULTRASOUND |  BLOOD |  BRAIN |  MOLYBDENUM |  DELIVERY...

5. Osteo-inductive effect of piezoelectric stimulation from the poly(l-lactic acid) scaffolds

Das, Ritopa |  Le, Duong... -  《plos one》 - 2024,19(2) - 共17页

摘要:Piezoelectric biomaterials can generate piezoelectrical charges in response to mechanical activation. These generated charges can directly stimulate bone regeneration by triggering signaling pathway t...
关键词: BONE-FORMATION |  GROWTH-FACTOR |  OSTEOGENESIS |  EXPRESSION |  RELEASE |  BMP-2 |  FORCE |  BETA |  CELL

6. Highly piezoelectric, biodegradable, and flexible amino acid nanofibers for medical applications

Chorsi, Meysam T. |  Le, Thinh T.... -  《science advances》 - 2023,9(24) - 共18页

摘要:Amino acid crystals are an attractive piezoelectric material as they have an ultrahigh piezoelectric coefficient and have an appealing safety profile for medical implant applications. Unfortunately, s...
关键词: MECHANICAL-PROPERTIES |  NIOBIUM |  ULTRASOUND |  NANOGENERATORS |  ZIRCONIUM |  TOXICITY |  ANTIMONY |  GROWTH |  ENERGY |  FILMS

7. Injectable and biodegradable piezoelectric hydrogel for osteoarthritis treatment

Vinikoor, Tra |  Dzidotor, Godwin K.... -  《Nature Communications》 - 2023,14(1) - 共18页

摘要:Osteoarthritis affects millions of people worldwide but current treatments using analgesics or anti-inflammatory drugs only alleviate symptoms of this disease. Here, we present an injectable, biodegra...
关键词: MESENCHYMAL STEM-CELLS |  INTENSITY PULSED ULTRASOUND |  MURINE KNEE-JOINT |  CARTILAGE-REPAIR |  ELECTRICAL-STIMULATION |  ADIPOSE-TISSUE |  BONE-MARROW |  COLLAGEN |  CHONDROGENESIS |  EXPRESSION

8. Electrical Stimulation for Immune Modulation in Cancer Treatments

Das, Ritopa |  Langou, Sofia... -  《frontiers in bioengineering and biotechnology》 - 2022,9 - 共18页 - 被引量:8

摘要:Immunotherapy is becoming a very common treatment for cancer, using approaches like checkpoint inhibition, T cell transfer therapy, monoclonal antibodies and cancer vaccination. However, these approac...
关键词: immunotherapy |  electrical stimulation |  electroporation |  cancer treatment |  immunostimulant |  immunogenic cell death |  THERAPEUTIC MONOCLONAL-ANTIBODY |  LEVEL DIRECT-CURRENT |  TUMOR-CELL VACCINE |  DENDRITIC CELLS...

9. Exercise-induced piezoelectric stimulation for cartilage regeneration in rabbits

Liu, Yang |  Dzidotor, Godwin... -  《science translational medicine》 - 2022,14(627) - 共15页 - 被引量:116

摘要:More than 32.5 million American adults suffer from osteoarthritis, and current treatments including pain medicines and anti-inflammatory drugs only alleviate symptoms but do not cure the disease. Here...
关键词: AUTOLOGOUS CHONDROCYTE TRANSPLANTATION |  MESENCHYMAL STEM-CELLS |  ELECTRICAL-STIMULATION |  ARTICULAR-CARTILAGE |  CHONDROGENIC DIFFERENTIATION |  STROMAL CELLS |  BONE-MARROW |  KNEE-JOINT |  REPAIR |  IMPLANTATION
检索条件作者:Le, Thinh T.
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