NSTL国家科技图书文献中心

1. Prevention of relapse to methamphetamine self-administration by environmental enrichment: involvement of glucocorticoid receptors SCIE Web of Science核心 NSTL国家科技图书文献中心

Nicolas, Celine | Hofford, Rebecca S.... - 《Psychopharmacology》 - 2022,239(4) - 1009～1018 - 共10页 - 被引量：3

摘要：Rationale In rodents, environmental enrichment (EE) produces both preventive and curative effects on drug addiction, and this effect is believed to depend at least in part on EE's actions on the stres...

关键词： Addiction | Environmental enrichment | Craving | Self-administration | Glucocorticoid receptors | STRESS | VULNERABILITY

2. Neuronal activity associated with cocaine preference: Effects of differential cocaine intake SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Chow, Jonathan J. | Hofford, Rebecca S.... - 《Neuropharmacology》 - 2021,184 - 共8页 - 被引量：3

摘要：Differences in overall cocaine intake can directly affect neuroadaptations, and this relationship can make it difficult to interpret neurobiological changes seen in drug-choice studies, since drug int...

关键词： Cocaine | Choice | Decision-making | Immunohistochemistry | In situ hybridization

3. Granulocyte-Colony Stimulating Factor Reduces Cocaine-Seeking and Downregulates Glutamatergic Synaptic Proteins in Medial Prefrontal Cortex SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Hofford, Rebecca S. | Euston, Tanner J.... - 《The Journal of neuroscience :》 - 2021,41(7) - 1553～1565 - 共13页 - 被引量：6

摘要：Psychostimulant use disorder is a major public health issue, and despite the scope of the problem there are currently no Food and Drug Administration (FDA)-approved treatments. There would be tremendo...

关键词： cocaine | cytokine | neuroimmune | reinstatement

4. Presence of a social peer enhances acquisition of remifentanil self-administration in male rats SCIE Web of Science核心 SCOPUS Scopus数据库 SSCI 社会科学引文索引 NSTL国家科技图书文献中心

Hofford, Rebecca S. | Bond, Paige N.... - 《Drug and alcohol dependence》 - 2020,213 - 共10页 - 被引量：4

摘要：Background: Social peers influence human drug use at every stage of addiction. Using a dual-compartment apparatus that allows for limited social contact, recent work has shown that cocaine self-admini...

关键词： Social | Remifentanil | Self-administration | Peer | Opioid

5. Neuroimmune mechanisms of psychostimulant and opioid use disorders SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Hofford, Rebecca S. | Russo, Scott J.... - 《The European Journal of Neuroscience》 - 2019,50(3/4) - 2562～2573 - 共12页 - 被引量：41

摘要：Substance use disorders are global health problems with few effective treatment options. Unfortunately, most potential pharmacological treatments are hindered by abuse potential of their own, limited ...

关键词： addiction | immune effects of drugs of abuse | inflammation | microbiome

6. The role of 'jackpot' stimuli in maladaptive decision-making: dissociable effects of D1/D2 receptor agonists and antagonists SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Smith, Aaron P. | Hofford, Rebecca S.... - 《Psychopharmacology》 - 2018,235(5) - 1427～1437 - 共11页 - 被引量：11

摘要：Laboratory experiments often model risk through a choice between a large, uncertain (LU) reward against a small, certain (SC) reward as an index of an individual's risk tolerance. An important factor ...

关键词： Discounting | Rat | Gambling | Dopamine | Suboptimal choice | Decision-making

7. Modified single prolonged stress reduces cocaine self-administration during acquisition regardless of rearing environment SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Hofford, Rebecca S. | Prendergast, Mark A.... - 《Behavioural Brain Research: An International Journal》 - 2018,338 - 143～152 - 共10页 - 被引量：7

摘要：Until recently, there were few rodent models available to study the interaction of post-traumatic stress disorder (PTSD) and drug taking. Like PTSD, single prolonged stress (SPS) produces hypothalamic...

关键词： Cocaine self-administration | Single prolonged stress | Isolation | Environmental enrichment | PTSD

8. Granulocyte Colony Stimulating Factor Enhances Reward Learning through Potentiation of Mesolimbic Dopamine System Function SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Kutlu, Munir Gunes | Brady, Lillian J.... - 《The Journal of Neuroscience: The Official Journal of the Society for Neuroscience》 - 2018,38(41) - 8845～8859 - 共15页 - 被引量：17

摘要：Deficits in motivation and cognition are hallmark symptoms of multiple psychiatric diseases. These symptoms are disruptive to quality of life and often do not improve with available medications. In re...

关键词： cytokine | dopamine | immune system | learning and memory | motivation | voltammetry

9. Rearing environment differentially modulates cocaine self-administration after opioid pretreatment: A behavioral economic analysis SCOPUS Scopus数据库 SCIE Web of Science核心 SSCI 社会科学引文索引 NSTL国家科技图书文献中心

Hofford, Rebecca S. | Beckmann, Joshua S.... - 《Drug and alcohol dependence》 - 2016,167 - 89～94 - 共6页 - 被引量：15

摘要：Background: Research has shown that previous experiences during development, especially if stressful, can alter an organism's response to opioids later in life. Given the previous literature on opioid...

关键词： Naltrexone | Morphine | Opioid | Environmental enrichment | Social isolation | Behavioral economics

10. Pharmacological manipulation of glucocorticoid receptors differentially affects cocaine self-administration in environmentally enriched and isolated rats SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Hofford, Rebecca S. | Prendergast, Mark A.... - 《Behavioural Brain Research: An International Journal》 - 2015,283 - 196～202 - 共7页 - 被引量：12

摘要：Social isolation rearing (isolated condition, IC) is used as a model of early life stress in rodents. Rats raised in this condition are often compared to rats raised in an environmentally enriched con...