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1. Post-Relapse Outcomes of Older Patients With NPM1 -Mutated AML Are Favorable With Allo Transplant in Second Remission NSTL国家科技图书文献中心

Frisch, Avraham |  Ganzel, Chezi... -  《European Journal of Haematology》 - 2025,114(4) - 641~649 - 共9页

摘要:Molecular assessment of measurable residual disease (MRD) in NPM1-mutated AML patients is a powerful prognostic tool to identify the risk of relapse. There is limited data regarding MRD-guided decisio...
关键词: Acute myeloid leukemia |  Measurable residual disease |  NPM1 |  relapse

2. CPX-351+/- gemtuzumab ozogamicin as induction therapy for adult patients with newly diagnosed, favourable-intermediate risk, FLT3-ITD negative, AML: A pilot study NSTL国家科技图书文献中心

Ganzel, Chezi |  Frisch, Avraham... -  《British Journal of Haematology》 - 2025,206(2) - 551~555 - 共5页

摘要:This pilot study evaluated CPX-351 in adults with newly diagnosed, favourable-intermediate risk, FLT3-ITD-negative AML. Twenty patients received CPX-351 for induction, with six also receiving gemtuzum...
关键词: AML |  cardiotoxicity |  CPX-351 |  gemtuzumab ozogamicin |  MRD |  vyxeos |  CPX‐351

3. Re-induction versus salvage for D14-resiudal acute myeloid leukemia: A retrospective multi-center study NSTL国家科技图书文献中心

Frisch, Avraham |  Aumann, Shlomzion... -  《Leukemia Research: A Forum for Studies on Leukemia and Normal Hemopoiesis》 - 2022,119 - 106902~106902 - 共7页

摘要:Remission assessment in acute myeloid leukemia has evolved over the recent years with the advent of molecular and flow-based minimal residual disease determination. Nonetheless, early time point such ...
关键词: D14 |  Acutemyeloidleukemia |  COLONY-STIMULATING FACTOR |  HIGH-DOSE CYTARABINE |  YOUNGER PATIENTS |  GEMTUZUMAB OZOGAMICIN |  COMPLETE REMISSION |  BLAST CLEARANCE |  OLDER PATIENTS |  G-CSF...

4. Gilteritinib monotherapy for relapsed/refractory FLT3 mutated acute myeloid leukemia: a real-world, multi-center, matched analysis SCIE Web of Science核心 NSTL国家科技图书文献中心

Shimony, Shai |  Canaani, Jonathan... -  《Annals of hematology》 - 2022,101(9) - 2001~2010 - 共10页

摘要:Patients with FLT3-mutated relapsed or refractory (R/R) acute myeloid leukemia (AML) have a dismal prognosis. Gilteritinib is a FLT3 tyrosine kinase inhibitor (TKI) recently approved for patients with...
关键词: Relapsed |  refractory AML |  FLT3 |  Gilteritinib |  MUTATIONS |  RECOMMENDATIONS |  CHEMOTHERAPY |  DIAGNOSIS |  PROGNOSIS

5. Venetoclax in combination with FLAG-IDA-based protocol for patients with acute myeloid leukemia: a real-world analysis SCIE Web of Science核心 NSTL国家科技图书文献中心

Wolach, Ofir |  Frisch, Avraham... -  《Annals of hematology》 - 2022,101(8) - 1719~1726 - 共8页

摘要:Venetoclax in combination with intensive therapies is explored in both the upfront and relapse/refractory (R/R) setting, and available data suggest that such regimens are effective albeit with added h...
关键词: High-risk AML |  Intensive chemotherapy |  Salvage |  Venetoclax |  RECOMMENDATIONS |  DIAGNOSIS

6. Midostaurin in combination with chemotherapy is most effective in patients with acute myeloid leukemia presenting with high FLT3-ITD allelic ratio who proceed to allogeneic stem cell transplantation while in first complete remission SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Ofran, Yishai |  Leiba, Ronit... -  《European Journal of Haematology》 - 2021,106(1) - 64~71 - 共8页

摘要:Objectives Midostaurin, a multikinase and FLT3 inhibitor, is the first non-chemotherapy agent approved and widely adopted for the treatment of FLT3-ITD acute myeloid leukemia (AML). Yet, its role in i...
关键词: acute myeloid leukemia |  allogeneic stem cell transplantation |  fms-like tyrosine kinase 3-internal tandem duplication |  midostaurin

7. How we treat older patients with acute myeloid leukaemia SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Frisch, Avraham |  Rowe, Jacob M.... -  《British Journal of Haematology》 - 2020,191(5) - 682~691 - 共10页

摘要:After decades when intensive chemotherapy remained the only effective anti-acute myeloid leukaemia (AML) treatment, a torrent of novel, less toxic agents are about to revolutionise AML therapy. Prolon...
关键词: acute myeloid leukaemia |  older adults |  molecular profile |  intensive chemotherapy |  novel agents

8. Midostaurin in combination with intensive chemotherapy is safe and associated with improved remission rates and higher transplantation rates in first remission-a multi-center historical control study SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Berger, Tamar |  Rozovski, Uri... -  《Annals of hematology》 - 2019,98(12) - 2711~2717 - 共7页

摘要:The addition of midostaurin, a FLT3-inhibitor, to intensive chemotherapy (IC) was previously shown to improve outcome of younger patients with FLT3-mutated AML. The toxicity and efficacy of adding mid...
关键词: Acute myeloid leukemia |  Midostaurin |  FLT3 mutation

9. Baseline Chest Computed Tomography for Early Diagnosis of Invasive Pulmonary Aspergillosis in Hemato-oncological Patients: A Prospective Cohort Study SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Bitterman, Roni |  Hardak, Emilia... -  《Clinical infectious diseases》 - 2019,69(10) - 1805~1808 - 共4页

摘要:Invasive pulmonary aspergillosis (IPA) has dire consequences in hemato-oncological patients. We report our experience with performing routine baseline chest computed tomography for early diagnosis of ...
关键词: invasive pulmonary aspergillosis |  invasive fungal infection |  baseline chest CT |  acute myeloid leukemia |  hematologic malignancy
检索条件作者:Frisch, Avraham

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