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1. Randomized trial of switching from prescribed non-selective non-steroidal anti-inflammatory drugs to prescribed celecoxib: the Standard care vs. Celecoxib Outcome Trial (SCOT) SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

MacDonald, Thomas M. |  Hawkey, Chris J.... -  《European Heart Journal: The Journal of the European Society of Cardiology》 - 2017,38(23) - 1843~1850 - 共9页 - 被引量:22

摘要:Background Selective cyclooxygenase-2 inhibitors and conventional non-selective non-steroidal anti-inflammatory drugs (nsNSAIDs) have been associated with adverse cardiovascular (CV) effects. We compa...
关键词: NSAIDs |  Celecoxib |  Cardiovascular |  Arthritis

3. Long-term cardiovascular safety of febuxostat compared with allopurinol in patients with gout (FAST): a multicentre, prospective, randomised, open-label, non-inferiority trial SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Mackenzie, Isla S. |  Ford, Ian... -  《The Lancet》 - 2020,396(10264) - 1745~1757 - 共13页 - 被引量:136

摘要:Background Febuxostat and allopurinol are urate-lowering therapies used to treat patients with gout. Following concerns about the cardiovascular safety of febuxostat, the European Medicines Agency rec...

4. Methods of a large prospective, randomised, open-label, blinded end-point study comparing morning versus evening dosing in hypertensive patients: the Treatment In Morning versus Evening (TIME) study

Rorie, David A. |  Rogers, Amy... -  《bmj open》 - 2016,6(2) - 共10页 - 被引量:50

摘要:

Introduction: Nocturnal blood pressure (BP) appears to be a better predictor of cardiovascular outcome than daytime BP. The BP lowering effects of most antihypertensive t...

关键词: BLOOD-PRESSURE CONTROL |  CARDIOVASCULAR EVENTS |  RISK |  CHRONOTHERAPY |  PREDICTORS |  GUIDELINES |  STATEMENT |  PATTERN |  STROKE |  DEATH

5. Protocol of the Febuxostat versus Allopurinol Streamlined Trial (FAST): a large prospective, randomised, open, blinded endpoint study comparing the cardiovascular safety of allopurinol and febuxostat in the management of symptomatic hyperuricaemia

MacDonald, Thomas M. |  Ford, Ian... -  《bmj open》 - 2014,4(7) - 共7页 - 被引量:58

摘要:Introduction: Gout affects 2.5% of the UK's adult population and is now the most common type of inflammatory arthritis. The long-term management of gout requires reduction of serum urate levels and th...
关键词: SERUM URIC-ACID |  INDEPENDENT PREDICTOR |  GOUT |  EPIDEMIOLOGY |  MORTALITY |  RISK
检索条件作者:Findlay, Evelyn

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