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1. Immune determinants of CAR-T cell expansion in solid tumor patients receiving GD2 CAR-T cell therapy NSTL国家科技图书文献中心

Kaczanowska, Sabina |  Murty, Tara... -  《Cancer Cell》 - 2024,42(1) - 35~51 - 共17页 - 被引量:15

摘要:Chimeric antigen receptor T cells (CAR-Ts) have remarkable efficacy in liquid tumors, but limited responses in solid tumors. We conducted a Phase I trial (NCT02107963) of GD2 CAR-Ts (GD2-CAR.OX40.28.z...
关键词: Crystal L |  Mackall |  ANTITUMOR-ACTIVITY |  R PACKAGE |  CLASSIFICATION |  EXHAUSTION |  SURVIVAL |  OSTEOSARCOMA |  MACROPHAGES |  PERSISTENCE...

2. A 45-Amino-Acid Scaffold Mined from the PDB for High-Affinity Ligand Engineering NSTL国家科技图书文献中心

Kruziki, Max A. |  Bhatnagar, Sumit... -  《Chemistry & biology》 - 2015,22(7) - 946~956 - 共11页

摘要:Small protein ligands can provide superior physiological distribution compared with antibodies, and improved stability, production, and specific conjugation. Systematic evaluation of the PDB identifie...
检索条件作者:Duong, Vandon

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