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1. Study on pro-inflammatory effect and mechanism of galectin-9 (LGALS9) in osteoarthritis: Exacerbating inflammatory response by activating JNK and ERK1/2 pathways NSTL国家科技图书文献中心

Ge, Lujie |  Lin, Changjian... -  《International Journal of Biological Macromolecules: Structure, Function and Interactions》 - 2024,280(Pt.1) - ARTN 135626～ - 共21页

摘要：Galectin-9 (LGALS9) plays an important role in the occurrence and development of many diseases, including immunity, infection, cancer, etc. Studies have found that LGALS9 can phosphorylate ERK1/2 in t...
关键词： Galectin-9 (LGALS9) |  Arthritis |  ERK1/2 pathways |  The pathogenesis of OA |  PROSTAGLANDIN E-2 |  NITRIC-OXIDE |  PATHOGENESIS |  PAIN |  HIP |  EPIDEMIOLOGY...
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2. LINC00665 aggravates the malignant phenotypes in chondrosarcoma cells through miR-665/FGF9 pathway NSTL国家科技图书文献中心

Qian, Jin |  Ge, Lujie... -  《International Journal of Biological Macromolecules: Structure, Function and Interactions》 - 2024,280(Pt.1) - ARTN 135727～ - 共13页

摘要：Long non-coding RNAs (lncRNAs) have been demonstrated to participate in a variety of physiological and pathological processes, including tumor initiation and development. Nevertheless, few of them hav...
关键词： LINC00665 |  Chondrosarcoma |  Proliferation |  miR-665 |  FGF9 |  LONG NONCODING RNA |  TARGETING FGF9 |  PROMOTES |  METASTASIS |  PROLIFERATION...
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3. LINC00665 aggravates the malignant phenotypes in chondrosarcoma cells through miR-665/FGF9 pathway NSTL国家科技图书文献中心

Qian, Jin |  Ge, Lujie... -  《International Journal of Biological Macromolecules》 - 2024,280(Pt.3) - 共13页

摘要：Long non-coding RNAs (lncRNAs) have been demonstrated to participate in a variety of physiological and pathological processes, including tumor initiation and development. Nevertheless, few of them hav...
关键词： LINC00665 |  Chondrosarcoma |  Proliferation |  miR-665 |  FGF9
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4. Self-Assembling Myristoylated Human alpha-Defensin 5 as a Next-Generation Nanobiotics Potentiates Therapeutic Efficacy in Bacterial Infection NSTL国家科技图书文献中心

Lei, Ruyi |  Hou, Jinchao... -  《ACS nano》 - 2018,12(6) - 5284～5296 - 共13页

摘要：The increasing prevalence of antibacterial resistance globally underscores the urgent need to the update of antibiotics. Here, we describe a strategy for inducing the self-assembly of a host defense a...
关键词： self-assembly |  antimicrobial peptide |  sepsis |  infection |  antibiotic resistance
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5. Nitidine Chloride Alleviates Inflammation and Cellular Senescence in Murine Osteoarthritis Through Scavenging ROS

Lin, Changjian |  Ge, Lujie... -  《Frontiers in Pharmacology》 - 2022,13 - 共15页

摘要：Osteoarthritis (OA) is one of the most common chronic musculoskeletal disorder worldwide, representing a major source of disability, pain and socioeconomic burden. Yet the effective pharmaceutical tre...
关键词： osteoarthritis |  nitidine chloride |  ROS |  senescence |  NLRP3 inflammasome |  MAPK |  NF-kappa B |  DRUG TARGET IDENTIFICATION |  POSTTRAUMATIC OSTEOARTHRITIS |  WEB SERVER...
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6. circFAM160A2 Promotes Mitochondrial Stabilization and Apoptosis Reduction in Osteoarthritis Chondrocytes by Targeting miR-505-3p and SIRT3

Bao, Jiapeng |  Lin, Changjian... -  《oxidative medicine and cellular longevity》 - 2021,2021 - 共13页

摘要：Competitive endogenous RNAs (ceRNAs), as a newly identified regulating mechanism, have been demonstrated to play a crucial role in various human diseases. An increasing number of recent studies have r...
关键词： ACTIVATION
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