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1. High CSF neurogranin level is related to lifetime reports of passive suicidal ideation in a population-based sample of older adults NSTL国家科技图书文献中心

Rymo, Irma |  Zetterberg, Henrik... -  《Journal of psychiatric research》 - 2025,181 - 340～347 - 共8页

摘要：Objective: To investigate the association of cerebrospinal fluid (CSF) levels of markers of synaptic dysfunction and neuronal damage, neurogranin (Ng) and neurofilament light chain (NfL), with suicida...
关键词： Synaptic dysfunction |  Cerebrospinal fluid biomarkers |  Suicidal ideation |  Older adults
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2. Data-driven evaluation of suitable immunogens for improved antibody selection NSTL国家科技图书文献中心

Waury, Katharina |  Kvartsberg, Hlin... -  《Protein science :》 - 2025,34(4) - e70100～e70100 - 共14页

摘要：Antibodies are indispensable in laboratory and clinical applications due to their high specificity and affinity for protein antigens. However, selecting the right protein fragments as immunogens for a...
关键词： antibody |  antigen |  disorder |  Human Protein Atlas |  immunogen |  protein structure
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3. Plasma brain-derived tau correlates with cerebral infarct volume NSTL国家科技图书文献中心

Gonzalez-Ortiz, Fern... |  Holmegaard, Lukas... -  《Journal of Internal Medicine》 - 2025,297(2) - 173～185 - 共13页

摘要：Background: A blood-based biomarker that accurately reflects neuronal injury in acute ischemic stroke could be an easily accessible and cost-effective complement to clinical and radiological evaluatio...
关键词： blood biomarkers |  brain-derived tau |  infarct volume |  stroke |  stroke severity |  brain‐derived tau
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4. Cerebrospinal fluid levels of NfM in relation to NfL and pNfH as prognostic markers in amyotrophic lateral sclerosis NSTL国家科技图书文献中心

Olofsson, Jennie |  Bergstrom, Sofia... -  《Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration》 - 2025,26(1/2) - 113～123 - 共11页

摘要：Objective: To evaluate the prognostic potential of neurofilament medium chain (NfM) in CSF from patients with ALS and explore its relationship with the extensively studied neurofilament light chain (N...
关键词： amyotrophic lateral sclerosis |  neurofilament medium |  survival |  progression |  cerebrospinal fluid
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5. Tau levels in platelets isolated from Huntington's disease patients serve as a biomarker of disease severity NSTL国家科技图书文献中心

Alpaugh, Melanie |  Lantero-Rodriguez, J...... -  《Journal of neurology》 - 2025,272(3) - Article 254～Article 254 - 共11页

摘要：Tau is a microtubule protein that is known to be hyperphosphorylated and to aggregate in several chronic neurodegenerative disorders. In many cases, in particular in Alzheimer's disease, the degree of...
关键词： Blood |  Plasma |  PBMC |  Cognition |  Phosphorylated tau |  NTA-tau
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6. Synaptosomal-Associated Protein 25 kDA (SNAP-25) Levels in Cerebrospinal Fluid: Implications for Alzheimer's Disease Diagnosis and Monitoring NSTL国家科技图书文献中心

Wolner, Sofia Hjorth |  Gleerup, Helena Soph...... -  《Synapse》 - 2025,79(2) - n/a～n/a - 共9页

摘要：Synaptic degeneration has been linked to cognitive decline. The presynaptic protein, synaptosomal-associated protein 25 kDA (SNAP-25), is crucial for synaptic transmission and has been suggested as a ...
关键词： Alzheimer's disease |  CSF |  diagnosis |  SNAP-25 |  SNAP‐25
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7. Loneliness and Biomarkers of Alzheimer's Disease, Axonal Damage, and Astrogliosis: A Coordinated Analysis of Two Longitudinal Cohorts NSTL国家科技图书文献中心

Terracciano, Antonio |  Walker, Keenan A.... -  《The journals of gerontology. Series B.Psychological sciences and social sciences》 - 2025,80(4) - gbaf006～gbaf006 - 共9页

摘要：Objectives Loneliness is associated with an elevated risk of dementia. There is mixed evidence from imaging studies on whether loneliness is associated with neuropathology in dementia-free adults. Thi...
关键词： Amyloid |  GFAP |  Lonely |  NfL |  Tau
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8. Strong diagnostic performance of plasma ptau217 for CSF biomarker-defined young-onset Alzheimer disease in a diagnostically heterogeneous clinical cohort NSTL国家科技图书文献中心

Eratne, Dhamidhu |  Li, Qiao-Xin... -  《Journal of neurology》 - 2025,272(1) - Article: 25～Article: 25 - 共12页

摘要：ObjectiveWe investigated diagnostic utility of phosphorylated tau 217 and 181 (ptau217, ptau181), glial fibrillary acidic protein (GFAP), amyloid beta 42 and 40 (A beta 42, A beta 40), and neurofilame...
关键词： ptau217 |  Alzheimer's disease |  Biomarker |  Diagnosis |  Dementia
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9. A prospective feasibility trial exploring novel biomarkers for neurotoxicity after isolated limb perfusion NSTL国家科技图书文献中心

Corderfeldt Keiller,... |  Axelsson, Markus... -  《Perfusion》 - 2024,39(8) - 1657～1666 - 共10页

摘要：Background: Isolated limb perfusion (ILP) is a regional cancer treatment in which high-dose chemotherapy is administered in an isolated extremity. The main side effect is regional toxicity, which occa...
关键词： extracorporeal circulation |  isolated limb perfusion |  neuroaxonal biomarkers |  regional toxicity |  simoa
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10. Plasma concentrations of glial fibrillary acidic protein, neurofilament light, and tau in Alexander disease NSTL国家科技图书文献中心

Ashton, Nicholas J. |  Di Molfetta, Gugliel...... -  《Neurological sciences》 - 2024,45(9) - 4519～4527 - 共9页 - 被引量：1

摘要：Introduction Alexander disease (AxD) is a rare leukodystrophy caused by dominant gain-of-function mutations in the gene encoding the astrocyte intermediate filament, glial fibrillary acidic protein (G...
关键词： GFAP |  Alexander disease |  Tau |  Neurofilaments |  Leukodystrophy |  Plasma |  BIOMARKER |  PREDICTION |  ONSET
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